{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T10:40:31Z","timestamp":1789123231879,"version":"build-2803163510"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T00:00:00Z","timestamp":1698969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T00:00:00Z","timestamp":1698969600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"the major technology application and demonstration project, Chengdu Science and Technology Bureau","award":["2021-YF09-00050-SN"],"award-info":[{"award-number":["2021-YF09-00050-SN"]}]},{"name":"1\u00b73\u00b75 Project for Disciplines of Excellence\u2013Clinical Research Incubation Project, West China Hospital, Sichuan University","award":["2020HXFH039"],"award-info":[{"award-number":["2020HXFH039"]}]},{"name":"1\u00b73\u00b75 Project for Disciplines of Excellence\u2013Clinical Research Incubation Project, West China Hospital, Sichuan University","award":["2020HXFH054"],"award-info":[{"award-number":["2020HXFH054"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Gastroenterol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Appendiceal bleeding is a rare cause of lower gastrointestinal bleeding, could be overlooked and diagnosed as obscure gastrointestinal bleeding. Due to limited real-world cases, the optimized management of appendiceal bleeding is unclear. We here shared our experiences in the past 20 years.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A retrospective study was conducted at West China Hospital of Sichuan University. We reviewed data of 28,175 colonoscopies from 43,095 gastrointestinal bleeding patients between June 2003 and June 2023. Six patients diagnosed as appendiceal bleeding were included. Data including symptoms, laboratory tests, imaging results, endoscopic findings, treatment and prognosis were collected and analyzed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Appendiceal bleeding accounts for 0.014% in gastrointestinal bleeding patients. Of the six patients, five were male, with a mean age of 48.5 years. Hematochezia was the most common symptom. The etiology included appendiceal angiodysplasia, appendicitis and appendectomy associated bleeding. Hemostasis was achieved by appendectomy, endoscopic therapy or medication according to different cases. One patient did not receive any treatment because of self-limiting bleeding.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The diagnosis of appendiceal bleeding is challenging, repeated flushing during endoscopy is helpful. Appendectomy is the priority option for treatment as well as the etiology clarification, therapeutic endoscopy and medication could be considered case by case.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12876-023-03025-6","type":"journal-article","created":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T13:02:24Z","timestamp":1699016544000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Clinical features, treatments and prognosis of appendiceal bleeding: a case series study"],"prefix":"10.1186","volume":"23","author":[{"given":"Xiao-cun","family":"Xing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-lin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,3]]},"reference":[{"key":"3025_CR1","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1186\/s40792-021-01234-3","volume":"7","author":"Y Maeda","year":"2013","unstructured":"Maeda Y, Saito S, Ohuchi M, Tamaoki Y, Nasu J, Baba H. Appendiceal bleeding in an elderly male: a case report and a review of the literature. Surg Case Rep. 2013;7:147.","journal-title":"Surg Case Rep"},{"key":"3025_CR2","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.ijscr.2017.06.038","volume":"39","author":"Z Shen","year":"2017","unstructured":"Shen Z, Huang YZ, Ning LM, Gao HC, Wang W. A case of lower digestive tract Hemorrhage caused by Appendicitis in China. Int J Surg Case Rep. 2017;39:34\u20135.","journal-title":"Int J Surg Case Rep"},{"key":"3025_CR3","doi-asserted-by":"publisher","first-page":"117","DOI":"10.3393\/ac.2016.32.3.117","volume":"32","author":"JM Choi","year":"2016","unstructured":"Choi JM, Lee SH, Lee SH, Ahn BK, Baek SU. Hematochezia due to angiodysplasia of the appendix. 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Informed consents were obtained from the patients.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Xiao-cun Xing, Jin-lin Yang and Xue Xiao have declared no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"377"}}