{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T18:13:10Z","timestamp":1789495990117,"version":"build-2803163510"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:00:00Z","timestamp":1716854400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:00:00Z","timestamp":1716854400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Gastroenterol"],"abstract":"Abstract<\/jats:title>\n Background<\/jats:title>\n Colorectal cancer (CRC) is the third leading cause of cancer and the second cause of cancer-related deaths in the world. Despite the infrastructure and the availability of organized screening programs, participation in their screening programs is less than the set goals. Considering the importance of informing the society about the prevention and early detection of colorectal cancer symptoms and the positive impact of mobile health technologies, the present research was conducted with the aim of designing and evaluating a colon cancer mobile application.<\/jats:p>\n <\/jats:sec>\n Methods<\/jats:title>\n The present research was conducted in two phases: software design and evaluation. In the first phase, the software was prepared using the cascade method. First, all the educational content related to colorectal cancer was collected through an expert panel with the participation of 10 specialists. Then the software was evaluated with alpha and beta testing, and the initial version was approved by users in terms of simplicity and usability. In the second phase, a parallel clinical randomized trial study was conducted with the aim of investigating the effect of a colon cancer mobile application on the early detection of colorectal cancer. In this stage, 204 volunteers participated; inclusion criteria were age 18\u201385 years, owning a smartphone and the ability to read and write. Participants were randomized into control and intervention groups. The intervention group was educated with the colon cancer application for education about colorectal cancer, and the control group was educated with a pamphlet. After education, both groups were screened for colorectal cancer symptoms, and the results were compared.<\/jats:p>\n <\/jats:sec>\n Results<\/jats:title>\n In the software evaluation phase, the application was used by 204 users. In this stage, 84 (41.2%) women and 120 (58.8%) men, with an average (Standard Deviation) age of 47.53 (13.68) participated. Participants were randomized in two groups, 103 people with an average (Standard Deviation) age of 47.62 (14.65) in intervention group and 101 people with an average (Standard Deviation) age of 47.44 (12.70) in control group. There were no significant differences between the demographic characteristics of age, gender, marriage, occupation, instruction level, digestive disease history, cancer history, cancer risk factors, and family history of cancer between the two groups (P<\/jats:italic>\u2009>\u20090.05). The Mann-Whitney U test indicated that there is a significant difference between the two groups of participants in self-assessment, willingness to do the screening, and the results of the assessment of colorectal cancer (P<\/jats:italic>\u2009<\u20090.05).<\/jats:p>\n <\/jats:sec>\n Conclusion<\/jats:title>\n The results of the research indicated the positive impact of the Colon Cancer Application on the abilities of the users of self-assessment of colon cancer. Therefore, based on the findings, it can be concluded that the use of the colon cancer mobile application is effective for colon cancer prevention and self-care.<\/jats:p>\n <\/jats:sec>\n Trial registration<\/jats:title>\n This study was registered in the Iranian Registry of Clinical Trials (https:\/\/irct.behdasht.gov.ir<\/jats:ext-link>) on 13\/2\/2024, with the IRCT ID: IRCT20210131050189N9.<\/jats:p>\n <\/jats:sec>","DOI":"10.1186\/s12876-024-03275-y","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T13:03:06Z","timestamp":1716901386000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Design and evaluation of a colon cancer mobile application"],"prefix":"10.1186","volume":"24","author":[{"given":"Amir","family":"Sadeghi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiva","family":"Salar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pardis Ketabi","family":"Moghadam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makan","family":"Cheraghpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raziyeh","family":"Ghafouri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,28]]},"reference":[{"issue":"1","key":"3275_CR1","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1038\/s41746-023-00786-y","volume":"6","author":"Y Zhu","year":"2023","unstructured":"Zhu Y, Zhang D-F, Wu H-L, Fu P-Y, Feng L, Zhuang K, et al. 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This is the online certificate of research ethical code: .This study was registered in the Iranian Registry of Clinical Trials () on February 13, 2024, with the IRCT ID: IRCT20210131050189N9.To observe the ethical considerations, hospitals were directed to agree to be part of the study; the research goals and procedures were elucidated to the participants; they were assured of information anonymity and confidentiality; and informed written consent was obtained from each participant and documented it. They participated in the study voluntarily and could leave the study at any stage.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"185"}}