{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T12:11:21Z","timestamp":1769170281609,"version":"3.49.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:00:00Z","timestamp":1741132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:00:00Z","timestamp":1741132800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Youth project of National Natural Science Foundation of China","award":["82204988"],"award-info":[{"award-number":["82204988"]}]},{"name":"Tianjin Administration of Traditional Chinese Medicine Youth project of China","award":["2021045"],"award-info":[{"award-number":["2021045"]}]},{"name":"Tianjin Administration of Traditional Chinese Medicine Youth project of China","award":["2021045"],"award-info":[{"award-number":["2021045"]}]},{"name":"Tianjin Administration of Traditional Chinese Medicine Youth project of China","award":["2021045"],"award-info":[{"award-number":["2021045"]}]},{"name":"Tianjin Administration of Traditional Chinese Medicine Youth project of China","award":["2021045"],"award-info":[{"award-number":["2021045"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of china","doi-asserted-by":"crossref","award":["82274253"],"award-info":[{"award-number":["82274253"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of china","doi-asserted-by":"crossref","award":["82274253"],"award-info":[{"award-number":["82274253"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of china","doi-asserted-by":"crossref","award":["82274253"],"award-info":[{"award-number":["82274253"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of china","doi-asserted-by":"crossref","award":["82274253"],"award-info":[{"award-number":["82274253"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of china","doi-asserted-by":"crossref","award":["82274253"],"award-info":[{"award-number":["82274253"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82074213"],"award-info":[{"award-number":["82074213"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82074213"],"award-info":[{"award-number":["82074213"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82074213"],"award-info":[{"award-number":["82074213"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82074213"],"award-info":[{"award-number":["82074213"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Gastroenterol"],"DOI":"10.1186\/s12876-025-03726-0","type":"journal-article","created":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T14:08:03Z","timestamp":1741183683000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The diagnostic criteria for psychosomatic research-revised (DCPR-R) in a National China multicenter cohort of patients with irritable bowel syndrome and overlapping gastroesophageal reflux disease"],"prefix":"10.1186","volume":"25","author":[{"given":"Peicai","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanping","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongmei","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanxia","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,3,5]]},"reference":[{"key":"3726_CR1","doi-asserted-by":"crossref","unstructured":"Sperber AD, Bangdiwala SI, Drossman DA, et al. Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study. Gastroenterology. 2021;160(1):99\u2013114.","DOI":"10.1053\/j.gastro.2020.04.014"},{"key":"3726_CR2","doi-asserted-by":"crossref","unstructured":"Huang KY, Wang FY, Lv M, et al. Irritable bowel syndrome: Epidemiology, overlap disorders, pathophysiology and treatment. World J Gastroenterol. 2023;29(26):4120\u20134135.","DOI":"10.3748\/wjg.v29.i26.4120"},{"key":"3726_CR3","doi-asserted-by":"crossref","unstructured":"Kutschke J, Harris JR, Bengtson MB. The relationships between IBS and perceptions of physical and mental health-a Norwegian twin study. BMC Gastroenterol. 2022;22(1):266.","DOI":"10.1186\/s12876-022-02340-8"},{"key":"3726_CR4","doi-asserted-by":"crossref","unstructured":"Drossman DA, Hasler WL. Rome IV-Functional GI Disorders: Disorders of Gut-Brain Interaction. Gastroenterology. 2016;150(6):1257-61.","DOI":"10.1053\/j.gastro.2016.03.035"},{"key":"3726_CR5","unstructured":"Barbara G, Feinle-Bisset C, Ghoshal UC, et al. The Intestinal Microenvironment and Functional Gastrointestinal Disorders. Gastroenterology. 2016:S0016-5085(16)00219-5."},{"key":"3726_CR6","doi-asserted-by":"crossref","unstructured":"Mayer EA, Labus J, Aziz Q, et al. Role of brain imaging in disorders of brain-gut interaction: a Rome Working Team Report. Gut. 2019;68(9):1701\u20131715.","DOI":"10.1136\/gutjnl-2019-318308"},{"key":"3726_CR7","doi-asserted-by":"crossref","unstructured":"de Bortoli N, Tolone S, Frazzoni M, et al. Gastroesophageal reflux disease, functional dyspepsia and irritable bowel syndrome: common overlapping gastrointestinal disorders. Ann Gastroenterol. 2018;31(6):639\u2013648.","DOI":"10.20524\/aog.2018.0314"},{"key":"3726_CR8","doi-asserted-by":"crossref","unstructured":"Eusebi LH, Ratnakumaran R, Yuan Y, et al. Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysis. Gut. 2018;67(3):430\u2013440.","DOI":"10.1136\/gutjnl-2016-313589"},{"key":"3726_CR9","doi-asserted-by":"crossref","unstructured":"El-Serag HB, Sweet S, Winchester CC, et al. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 2014;63(6):871\u2009\u2212\u200980.","DOI":"10.1136\/gutjnl-2012-304269"},{"key":"3726_CR10","doi-asserted-by":"crossref","unstructured":"Broderick R, Fuchs KH, Breithaupt W, et al. Clinical Presentation of Gastroesophageal Reflux Disease: A Prospective Study on Symptom Diversity and Modification of Questionnaire Application. Dig Dis. 2020;38(3):188\u2013195.","DOI":"10.1159\/000502796"},{"key":"3726_CR11","doi-asserted-by":"crossref","unstructured":"Katz PO, Gerson LB, Vela MF. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol. 2013;108(3):308\u2009\u2212\u200928; quiz 329.","DOI":"10.1038\/ajg.2012.444"},{"key":"3726_CR12","doi-asserted-by":"crossref","unstructured":"Savarino E, Bredenoord AJ, Fox M, et al. International Working Group for Disorders of Gastrointestinal Motility and Function. Expert consensus document: Advances in the physiological assessment and diagnosis of GERD. Nat Rev Gastroenterol Hepatol. 2017;14(11):665\u2013676.","DOI":"10.1038\/nrgastro.2017.130"},{"key":"3726_CR13","doi-asserted-by":"crossref","unstructured":"Alshammari SA, Almutairi MN, Alomar MO,et al. Overlap Between Gastroesophageal Reflux Disease and Irritable Bowel Syndrome and Its Impact on Quality of Life. Cureus. 2023;15(12):e50840","DOI":"10.7759\/cureus.50840"},{"key":"3726_CR14","doi-asserted-by":"crossref","unstructured":"de Bortoli N, Martinucci I, Bellini M, et al. Overlap of functional heartburn and gastroesophageal reflux disease with irritable bowel syndrome. World J Gastroenterol. 2013;19(35):5787-97.","DOI":"10.3748\/wjg.v19.i35.5787"},{"key":"3726_CR15","doi-asserted-by":"crossref","unstructured":"Zamani M, Alizadeh-Tabari S, Zamani V. Systematic review with meta-analysis: the prevalence of anxiety and depression in patients with irritable bowel syndrome. Aliment Pharmacol Ther. 2019;50(2):132\u2013143.","DOI":"10.1111\/apt.15325"},{"key":"3726_CR16","doi-asserted-by":"crossref","unstructured":"Lovell RM, Ford AC. Prevalence of gastro-esophageal reflux-type symptoms in individuals with irritable bowel syndrome in the community: a meta-analysis. Am J Gastroenterol. 2012;107(12):1793\u2009\u2212\u2009801; quiz 1802.","DOI":"10.1038\/ajg.2012.336"},{"key":"3726_CR17","doi-asserted-by":"crossref","unstructured":"Lee SW, Chang CS. Impact of Overlapping Functional Gastrointestinal Disorders on the Quality of Life in Patients With Gastroesophageal Reflux Disease. J Neurogastroenterol Motil. 2021;27(2):176\u2013184.","DOI":"10.5056\/jnm19006"},{"key":"3726_CR18","doi-asserted-by":"crossref","unstructured":"Porcelli P, Guidi J. The Clinical Utility of the Diagnostic Criteria for Psychosomatic Research: A Review of Studies. Psychother Psychosom. 2015;84(5):265\u2009\u2212\u200972.","DOI":"10.1159\/000430788"},{"key":"3726_CR19","doi-asserted-by":"crossref","unstructured":"Fava GA, Freyberger HJ, Bech P, et al. Diagnostic criteria for use in psychosomatic research. Psychother Psychosom. 1995;63(1):1\u20138.","DOI":"10.1159\/000288931"},{"key":"3726_CR20","doi-asserted-by":"crossref","unstructured":"Fava GA, Cosci F, Sonino N. Current Psychosomatic Practice. Psychother Psychosom. 2017;86(1):13\u201330.","DOI":"10.1159\/000448856"},{"key":"3726_CR21","doi-asserted-by":"crossref","unstructured":"Porcelli P, De Carne M, Todarello O. Prediction of treatment outcome of patients with functional gastrointestinal disorders by the diagnostic criteria for psychosomatic research. Psychother Psychosom. 2004;73(3):166\u2009\u2212\u200973.","DOI":"10.1159\/000076454"},{"key":"3726_CR22","doi-asserted-by":"crossref","unstructured":"Gostoli S, Montecchiarini M, Urgese A, et al. The clinical utility of a comprehensive psychosomatic assessment in the program for colorectal cancer prevention: a cross-sectional study. Sci Rep. 2021;11(1):15575.","DOI":"10.1038\/s41598-021-95171-8"},{"key":"3726_CR23","doi-asserted-by":"crossref","unstructured":"Porcelli P, De Carne M, Leandro G. Distinct associations of DSM-5 Somatic Symptom Disorder, the Diagnostic Criteria for Psychosomatic Research-Revised (DCPR-R) and symptom severity in patients with irritable bowel syndrome. Gen Hosp Psychiatry. 2020;64:56\u201362.","DOI":"10.1016\/j.genhosppsych.2020.03.004"},{"key":"3726_CR24","doi-asserted-by":"crossref","unstructured":"Cosci F, Svicher A, Romanazzo S, et al. Criterion-related validity in a sample of migraine outpatients: the diagnostic criteria for psychosomatic research. CNS Spectr. 2020;25(4):545\u2013551.","DOI":"10.1017\/S1092852919001536"},{"key":"3726_CR25","doi-asserted-by":"crossref","unstructured":"Grayson M. Irritable bowel syndrome. Nature. 2016;533(7603):S101.","DOI":"10.1038\/533S101a"},{"key":"3726_CR26","doi-asserted-by":"crossref","unstructured":"Whitehead WE, Palsson OS, Simr\u00e9n M. Irritable bowel syndrome: what do the new Rome IV diagnostic guidelines mean for patient management? Expert Rev Gastroenterol Hepatol. 2017;11(4):281\u2013283.","DOI":"10.1080\/17474124.2017.1292130"},{"key":"3726_CR27","doi-asserted-by":"crossref","unstructured":"Jones R, Junghard O, Dent J, Vet al. Development of the GerdQ, a tool for the diagnosis and management of gastro-oesophageal reflux disease in primary care. Aliment Pharmacol Ther. 2009;30(10):1030-8.","DOI":"10.1111\/j.1365-2036.2009.04142.x"},{"key":"3726_CR28","doi-asserted-by":"crossref","unstructured":"Bai Y, Du Y, Zou D, et al. Gastroesophageal Reflux Disease Questionnaire (GerdQ) in real-world practice: a national multicenter survey on 8065 patients. J Gastroenterol Hepatol. 2013;28(4):626\u2009\u2212\u200931.","DOI":"10.1111\/jgh.12125"},{"key":"3726_CR29","doi-asserted-by":"crossref","unstructured":"Piolanti A, Offidani E, Guidi J, et al. Use of the Psychosocial Index: A Sensitive Tool in Research and Practice. Psychother Psychosom. 2016;85(6):337\u2013345.","DOI":"10.1159\/000447760"},{"key":"3726_CR30","doi-asserted-by":"crossref","unstructured":"Li L, Peng T, Liu R, et al. Development of the psychosomatic symptom scale (PSSS) and assessment of its reliability and validity in general hospital patients in China. Gen Hosp Psychiatry. 2020;64:1\u20138.","DOI":"10.1016\/j.genhosppsych.2020.01.008"},{"key":"3726_CR31","doi-asserted-by":"crossref","unstructured":"Topp CW, \u00d8stergaard SD, S\u00f8ndergaard S, et al. The WHO-5 Well-Being Index: a systematic review of the literature. Psychother Psychosom. 2015;84(3):167\u2009\u2212\u200976.","DOI":"10.1159\/000376585"},{"key":"3726_CR32","doi-asserted-by":"crossref","unstructured":"Zhang Y, Wang X, Carrozzino D, et al. Clinimetric properties of the Chinese version of the Euthymia Scale. Clin Psychol Psychother. 2022;29(1):360\u2013366.","DOI":"10.1002\/cpp.2592"},{"key":"3726_CR33","doi-asserted-by":"crossref","unstructured":"Levis B, Benedetti A, Thombs BD; DEPRESsion Screening Data (DEPRESSD) Collaboration. Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis. BMJ. 2019;365:l1476.","DOI":"10.1136\/bmj.l1476"},{"key":"3726_CR34","doi-asserted-by":"crossref","unstructured":"Yrd-Bredbenner C, Eck K, Quick V. GAD-7, GAD-2, and GAD-mini: Psychometric properties and norms of university students in the United States. Gen Hosp Psychiatry. 2021;69:61\u201366.","DOI":"10.1016\/j.genhosppsych.2021.01.002"},{"key":"3726_CR35","doi-asserted-by":"crossref","unstructured":"Pourhoseingholi A, Vahedi M, Pourhoseingholi MA, et al. Irritable bowel syndrome, gastro-oesophageal reflux disease and dyspepsia: overlap analysis using loglinear models. Arab J Gastroenterol. 2012;13(1):20\u2009\u2212\u20093.","DOI":"10.1016\/j.ajg.2012.02.005"},{"key":"3726_CR36","doi-asserted-by":"crossref","unstructured":"Gasiorowska A, Poh CH, Fass R. Gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS)--is it one disease or an overlap of two disorders? Dig Dis Sci. 2009;54(9):1829-34.","DOI":"10.1007\/s10620-008-0594-2"},{"key":"3726_CR37","unstructured":"Drossman DA. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. Gastroenterology. 2016; 19:S0016-5085(16)00223-7."},{"key":"3726_CR38","doi-asserted-by":"crossref","unstructured":"Jung HK, Tae CH, Song KH, et al. Korean Society of Neurogastroenterology and Motility. 2020 Seoul Consensus on the Diagnosis and Management of Gastroesophageal Reflux Disease. J Neurogastroenterol Motil. 2021;27(4):453\u2013481.","DOI":"10.5056\/jnm21077"},{"key":"3726_CR39","doi-asserted-by":"crossref","unstructured":"Lei WY, Chang WC, Wen SH, et al. Impact of concomitant dyspepsia and irritable bowel syndrome on symptom burden in patients with gastroesophageal reflux disease. J Formos Med Assoc. 2019;118(4):797\u2013806.","DOI":"10.1016\/j.jfma.2018.12.002"},{"key":"3726_CR40","doi-asserted-by":"crossref","unstructured":"Heading RC, M\u00f6nnikes H, Tholen A, et al. Prediction of response to PPI therapy and factors influencing treatment outcome in patients with GORD: a prospective pragmatic trial using pantoprazole. BMC Gastroenterol. 2011;11:52.","DOI":"10.1186\/1471-230X-11-52"},{"key":"3726_CR41","doi-asserted-by":"crossref","unstructured":"Katz PO, Gerson LB, Vela MF. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol. 2013;108(3):308\u2009\u2212\u200928; quiz 329.","DOI":"10.1038\/ajg.2012.444"},{"key":"3726_CR42","doi-asserted-by":"crossref","unstructured":"Sanna L, Stuart AL, Berk M, et al. Gastro oesophageal reflux disease (GORD)-related symptoms and its association with mood and anxiety disorders and psychological symptomology: a population-based study in women. BMC Psychiatry. 2013;13:194.","DOI":"10.1186\/1471-244X-13-194"},{"key":"3726_CR43","doi-asserted-by":"crossref","unstructured":"Chey WD, Kurlander J, Eswaran S. Irritable bowel syndrome: a clinical review. JAMA. 2015;313(9):949\u2009\u2212\u200958.","DOI":"10.1001\/jama.2015.0954"},{"key":"3726_CR44","doi-asserted-by":"crossref","unstructured":"Fava GA, Cosci F, Sonino N. Current Psychosomatic Practice. Psychother Psychosom. 2017;86(1):13\u201330.","DOI":"10.1159\/000448856"},{"key":"3726_CR45","doi-asserted-by":"crossref","unstructured":"Henningsen P. Management of somatic symptom disorder. Dialogues Clin Neurosci. 2018;20(1):23\u201331.","DOI":"10.31887\/DCNS.2018.20.1\/phenningsen"},{"key":"3726_CR46","doi-asserted-by":"crossref","unstructured":"Simr\u00e9n M, Tack J. New treatments and therapeutic targets for IBS and other functional bowel disorders. Nat Rev Gastroenterol Hepatol. 2018;15(10):589\u2013605.","DOI":"10.1038\/s41575-018-0034-5"},{"key":"3726_CR47","doi-asserted-by":"crossref","unstructured":"Porcelli P, Rafanelli C. Criteria for psychosomatic research (DCPR) in the medical setting. Curr Psychiatry Rep. 2010;12(3):246\u2009\u2212\u200954.","DOI":"10.1007\/s11920-010-0104-z"},{"key":"3726_CR48","doi-asserted-by":"crossref","unstructured":"Xu W, Jiang W, Ding R, et al. Study of Rates and Factors Associated to Psychosomatic Syndromes Assessed Using the Diagnostic Criteria for Psychosomatic Research across Different Clinical Settings. Psychother Psychosom. 2024;93(6):386\u2013396.","DOI":"10.1159\/000541404"},{"key":"3726_CR49","doi-asserted-by":"crossref","unstructured":"Porcelli P, Todarello O. Psychological factors affecting functional gastrointestinal disorders. Adv Psychosom Med. 2007;28:34\u201356.","DOI":"10.1159\/000106796"},{"key":"3726_CR50","doi-asserted-by":"crossref","unstructured":"Huang WL, Liao SC. Subgrouping Somatic Symptom Disorder: An Analysis Based on the Diagnostic Criteria for Psychosomatic Research. Psychother Psychosom. 2018;87(5):316\u2013318.","DOI":"10.1159\/000492227"}],"container-title":["BMC Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12876-025-03726-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12876-025-03726-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12876-025-03726-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T14:08:38Z","timestamp":1741183718000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/10.1186\/s12876-025-03726-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,5]]},"references-count":50,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3726"],"URL":"https:\/\/doi.org\/10.1186\/s12876-025-03726-0","relation":{},"ISSN":["1471-230X"],"issn-type":[{"value":"1471-230X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,5]]},"assertion":[{"value":"25 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 March 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The studies involving human participants were reviewed and approved by the IEC for Clinical Research of Zhongda Hospital, Affiliated with Southeast University (2021ZDSYLL349-P02).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The patients\/participants provided their written informed consent to participate in this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}],"article-number":"136"}}