{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T23:20:46Z","timestamp":1785885646983,"version":"3.56.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Foshan Hospital Of Traditional Chinese Medicine","award":["20233002"],"award-info":[{"award-number":["20233002"]}]},{"DOI":"10.13039\/501100011478","name":"Foshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["2220001005125"],"award-info":[{"award-number":["2220001005125"]}],"id":[{"id":"10.13039\/501100011478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011478","name":"Foshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["2220001005125"],"award-info":[{"award-number":["2220001005125"]}],"id":[{"id":"10.13039\/501100011478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011478","name":"Foshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["2220001005125"],"award-info":[{"award-number":["2220001005125"]}],"id":[{"id":"10.13039\/501100011478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011478","name":"Foshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["2220001005125"],"award-info":[{"award-number":["2220001005125"]}],"id":[{"id":"10.13039\/501100011478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011478","name":"Foshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["2220001005125"],"award-info":[{"award-number":["2220001005125"]}],"id":[{"id":"10.13039\/501100011478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011478","name":"Foshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["2220001005125"],"award-info":[{"award-number":["2220001005125"]}],"id":[{"id":"10.13039\/501100011478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011478","name":"Foshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["2220001005125"],"award-info":[{"award-number":["2220001005125"]}],"id":[{"id":"10.13039\/501100011478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011478","name":"Foshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["2220001005125"],"award-info":[{"award-number":["2220001005125"]}],"id":[{"id":"10.13039\/501100011478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011478","name":"Foshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["2220001005125"],"award-info":[{"award-number":["2220001005125"]}],"id":[{"id":"10.13039\/501100011478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011478","name":"Foshan Science and Technology Bureau","doi-asserted-by":"publisher","award":["2220001005125"],"award-info":[{"award-number":["2220001005125"]}],"id":[{"id":"10.13039\/501100011478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Gastroenterol"],"DOI":"10.1186\/s12876-025-03900-4","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T07:57:20Z","timestamp":1745913440000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Dysregulated gastric microbial communities and functional shifts in chronic atrophic versus non-atrophic gastritis: a Helicobacter pylori-Negative observational study"],"prefix":"10.1186","volume":"25","author":[{"given":"Hong","family":"Yao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"She","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingfeng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongsong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhong","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yubin","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianmin","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinfeng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengbin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"key":"3900_CR1","doi-asserted-by":"publisher","unstructured":"Dixon MF, Genta RM, Yardley JH et al. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994.[J]. American Journal of Surgical Pathology. 1996;20(10):1161\u20131181.https:\/\/doi.org\/10.1148\/radiology.203.2.434","DOI":"10.1148\/radiology.203.2.434"},{"key":"3900_CR2","doi-asserted-by":"publisher","unstructured":"Tytgat GNJ. The Sydney System: endoscopic division. Endoscopic appearances in gastritis\/duodenitis. J Gastroenterol Hepatol 6: 223\u2013234[J]. Journal of Gastroenterology & Hepatology, 1991;6(3):223\u2013234.https:\/\/doi.org\/10.1111\/j.1440-1746.1991.tb01469.x","DOI":"10.1111\/j.1440-1746.1991.tb01469.x"},{"key":"3900_CR3","unstructured":"Correa P. Human gastric carcinogenesis: A multistep and multifactorial Process\u2014First American Cancer society award lecture on Cancer epidemiology and Prevention[J]. Cancer research, 1992;52(24):6735\u201340."},{"issue":"7","key":"3900_CR4","doi-asserted-by":"publisher","first-page":"3055","DOI":"10.1007\/s10620-021-07146-4","volume":"67","author":"YJ Hwang","year":"2022","unstructured":"Hwang YJ, Choi Y, Kim N, et al. The difference of endoscopic and histologic improvements of atrophic gastritis and intestinal metaplasia after Helicobacter pylori eradication. Dig Dis Sci. 2022;67(7):3055\u201366. https:\/\/doi.org\/10.1007\/s10620-021-07146-4. Epub 2021 Aug 7. PMID: 34365533.","journal-title":"Dig Dis Sci"},{"issue":"8","key":"3900_CR5","doi-asserted-by":"publisher","first-page":"e0255601","DOI":"10.1371\/journal.pone.0255601","volume":"16","author":"N Aumpan","year":"2021","unstructured":"Aumpan N, Vilaichone RK, Pornthisarn B, et al. Predictors for regression and progression of intestinal metaplasia (IM): A large population-based study from low prevalence area of gastric cancer (IM-predictor trial). PLoS ONE. 2021;16(8):e0255601. https:\/\/doi.org\/10.1371\/journal.pone.0255601. PMID: 34379655; PMCID: PMC8357097.","journal-title":"PLoS ONE"},{"key":"3900_CR6","doi-asserted-by":"publisher","unstructured":"Uemura N, Okamoto S, Yamamoto S et al. Helicobacter pylori infection and the development of gastric cancer. N. Engl. J. Med. 345, 784\u2013789[J]. New England Journal of Medicine. 2001;345(11):784\u2013789.https:\/\/doi.org\/10.1056\/NEJMoa001999","DOI":"10.1056\/NEJMoa001999"},{"key":"3900_CR7","doi-asserted-by":"publisher","unstructured":"Dias-J\u00e1come E, Lib\u00e2nio, Borges-Canha M, et al. Gastric microbiota and carcinogenesis: the role of non-Helicobacter pylori bacteria: a systematic review[J]. Revista Espa\u00f1ola De Enfermedades Digestivas. 2016;108. https:\/\/doi.org\/10.17235\/reed.2016.4261\/2016.","DOI":"10.17235\/reed.2016.4261\/2016"},{"key":"3900_CR8","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-020-06118-4","author":"W Ruan","year":"2020","unstructured":"Ruan W, Engevik MA, Spinler JK, et al. Exploration[J] Dig Dis Sci. 2020;65(3). https:\/\/doi.org\/10.1007\/s10620-020-06118-4. Healthy Human Gastrointestinal Microbiome: Composition and Function After a Decade of."},{"issue":"9","key":"3900_CR9","doi-asserted-by":"publisher","first-page":"gutjnl","DOI":"10.1136\/gutjnl-2019-318556","volume":"68","author":"AJ Scott","year":"2019","unstructured":"Scott AJ, Alexander JL, Merrifield CA, et al. International Cancer Microbiome consortium consensus statement on the role of the human Microbiome in carcinogenesis[J]. Gut. 2019;68(9):gutjnl\u20132019. https:\/\/doi.org\/10.1136\/gutjnl-2019-318556.","journal-title":"Gut"},{"issue":"7","key":"3900_CR10","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.3748\/wjg.v29.i7.1202","volume":"29","author":"D Nikitina","year":"2023","unstructured":"Nikitina D, Lehr K, Vilchez-Vargas R, et al. Comparison of genomic and transcriptional Microbiome analysis in gastric cancer patients and healthy individuals. World J Gastroenterol. 2023;29(7):1202\u201318. https:\/\/doi.org\/10.3748\/wjg.v29.i7.1202. PMID: 36926663; PMCID: PMC10011954.","journal-title":"World J Gastroenterol"},{"key":"3900_CR11","doi-asserted-by":"crossref","unstructured":"Yu T, Lu T, Deng W, et al. Microbiome and function alterations in the gastric mucosa of asymptomatic patients with Helicobacter. pylori infection[J]. Helicobacter; 2023.","DOI":"10.1111\/hel.12965"},{"issue":"3","key":"3900_CR12","doi-asserted-by":"publisher","first-page":"149","DOI":"10.3969\/j.issn.1008-7125.2023.03.004","volume":"28","author":"G Branch","year":"2023","unstructured":"Chinese Medical Association, Branch G, Association CM, Branch G, Collaborative Group on Digestive System Tumors, Jingyuan F, et al. Chinese guidelines for the diagnosis and treatment of chronic gastritis (2022, Shanghai) [J]. Gastroenterology. 2023;28(3):149\u201380. https:\/\/doi.org\/10.3969\/j.issn.1008-7125.2023.03.004.","journal-title":"Gastroenterology"},{"issue":"3","key":"3900_CR13","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1038\/ismej.2015.131","volume":"10","author":"JB Logue","year":"2016","unstructured":"Logue JB, Stedmon CA, Kellerman AM, et al. Experimental insights into the importance of aquatic bacterial community composition to the degradation of dissolved organic matter. ISME J. 2016;10(3):533\u201345. https:\/\/doi.org\/10.1038\/ismej.2015.131. Epub 2015 Aug 21. PMID: 26296065; PMCID: PMC4817675.","journal-title":"ISME J"},{"issue":"7","key":"3900_CR14","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1038\/nmeth.3869","volume":"13","author":"BJ Callahan","year":"2016","unstructured":"Callahan BJ, McMurdie PJ, Rosen MJ, et al. DADA2: High-resolution sample inference from illumina amplicon data. Nat Methods. 2016;13(7):581\u20133. https:\/\/doi.org\/10.1038\/nmeth.3869. Epub 2016 May 23. PMID: 27214047; PMCID: PMC4927377.","journal-title":"Nat Methods"},{"issue":"9","key":"3900_CR15","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1038\/s41587-019-0252-6","volume":"37","author":"E Bolyen","year":"2019","unstructured":"Bolyen E, Rideout JR, Dillon MR, et al. Author correction: reproducible, interactive, scalable and extensible Microbiome data science using QIIME 2. Nat Biotechnol. 2019;37(9):1091. https:\/\/doi.org\/10.1038\/s41587-019-0252-6. Erratum for: Nat Biotechnol. 2019;37(8):852\u2013857. PMID: 31399723.","journal-title":"Nat Biotechnol"},{"key":"3900_CR16","doi-asserted-by":"publisher","unstructured":"Correa P, Piazuelo MB, Camargo MC. The future of gastric cancer prevention. Gastric Cancer. 2004;7(1):9\u201316. https:\/\/doi.org\/10.1007\/s10120-003-0265-0. PMID: 15052434.","DOI":"10.1007\/s10120-003-0265-0"},{"issue":"12","key":"3900_CR17","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1136\/gutjnl-2020-320839","volume":"69","author":"AC Ford","year":"2020","unstructured":"Ford AC, Yuan Y, Moayyedi P. Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis. Gut. 2020;69(12):2113\u201321. https:\/\/doi.org\/10.1136\/gutjnl-2020-320839. Epub 2020 Mar 23. PMID: 32205420.","journal-title":"Gut"},{"key":"3900_CR18","doi-asserted-by":"publisher","unstructured":"Sung JJ, Lin SR, Ching JY et al. Atrophy and intestinal metaplasia one year after cure of H. pylori infection: a prospective, randomized study. Gastroenterology. 2000;119(1):7\u201314. https:\/\/doi.org\/10.1053\/gast.2000.8550. PMID: 10889149.","DOI":"10.1053\/gast.2000.8550"},{"issue":"1","key":"3900_CR19","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1053\/j.gastro.2010.09.048","volume":"140","author":"JL Lofgren","year":"2011","unstructured":"Lofgren JL, Whary MT, Ge Z, et al. Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia. Gastroenterology. 2011;140(1):210\u201320. https:\/\/doi.org\/10.1053\/j.gastro.2010.09.048. Epub 2010 Oct 13. PMID: 20950613; PMCID: PMC3006487.","journal-title":"Gastroenterology"},{"issue":"7","key":"3900_CR20","doi-asserted-by":"publisher","first-page":"1266","DOI":"10.1136\/gutjnl-2021-324489","volume":"71","author":"SK Kwon","year":"2022","unstructured":"Kwon SK, Park JC, Kim KH, et al. Human gastric microbiota transplantation recapitulates premalignant lesions in germ-free mice. Gut. 2022;71(7):1266\u201376. https:\/\/doi.org\/10.1136\/gutjnl-2021-324489. Epub 2021 Aug 13. PMID: 34389621.","journal-title":"Gut"},{"issue":"1","key":"3900_CR21","doi-asserted-by":"publisher","first-page":"e0077221","DOI":"10.1128\/msphere.00772-21","volume":"7","author":"Z Shen","year":"2022","unstructured":"Shen Z, Dzink-Fox J, Feng Y, et al. Gastric Non-Helicobacter pylori Urease-Positive Staphylococcus epidermidis and Streptococcus salivarius isolated from humans have contrasting effects on H. pylori-Associated gastric pathology and host immune responses in a murine model of gastric Cancer. mSphere. 2022;7(1):e0077221. https:\/\/doi.org\/10.1128\/msphere.00772-21. Epub 2022 Feb 9. PMID: 35138124; PMCID: PMC8826947.","journal-title":"mSphere"},{"issue":"6","key":"3900_CR22","doi-asserted-by":"publisher","first-page":"484","DOI":"10.3390\/antibiotics13060484","volume":"13","author":"C Sgamato","year":"2024","unstructured":"Sgamato C, Rocco A, Compare D, et al. Exploring the link between Helicobacter pylori, gastric microbiota and gastric Cancer. Antibiot (Basel). 2024;13(6):484. https:\/\/doi.org\/10.3390\/antibiotics13060484. PMID: 38927151; PMCID: PMC11201017.","journal-title":"Antibiot (Basel)"},{"key":"3900_CR23","doi-asserted-by":"publisher","unstructured":"Wang Z, Gao X, Zeng R, et al. Changes of the gastric mucosal Microbiome associated with histological stages of gastric Carcinogenesis[J]. Front Microbiol. 2020;11. https:\/\/doi.org\/10.3389\/fmicb.2020.00997.","DOI":"10.3389\/fmicb.2020.00997"},{"key":"3900_CR24","doi-asserted-by":"publisher","unstructured":"He C, Peng C, Lu N et al. Convergent dysbiosis of gastric mucosa and fluid microbiome during stomach carcinogenesis. Gastric Cancer. 2022;25(5):837\u2013849. https:\/\/doi.org\/10.1007\/s10120-022-01302-z. Epub 2022 Jun 4. PMID: 35661945.","DOI":"10.1007\/s10120-022-01302-z"},{"issue":"28","key":"3900_CR25","doi-asserted-by":"publisher","first-page":"3599","DOI":"10.1038\/s41388-022-02377-9","volume":"41","author":"C Liu","year":"2022","unstructured":"Liu C, Ng SK, Ding Y, et al. Meta-analysis of mucosal microbiota reveals universal microbial signatures and dysbiosis in gastric carcinogenesis. Oncogene. 2022;41(28):3599\u2013610. https:\/\/doi.org\/10.1038\/s41388-022-02377-9. Epub 2022 Jun 9. PMID: 35680985; PMCID: PMC9270228.","journal-title":"Oncogene"},{"key":"3900_CR26","doi-asserted-by":"publisher","first-page":"1105811","DOI":"10.3389\/fcimb.2022.1105811","volume":"12","author":"Y Guo","year":"2023","unstructured":"Guo Y, Cao XS, Zhou MG, et al. Gastric microbiota in gastric cancer: different roles of Helicobacter pylori and other microbes. Front Cell Infect Microbiol. 2023;12:1105811. https:\/\/doi.org\/10.3389\/fcimb.2022.1105811. PMID: 36704105; PMCID: PMC9871904.","journal-title":"Front Cell Infect Microbiol"},{"issue":"3","key":"3900_CR27","doi-asserted-by":"publisher","first-page":"365","DOI":"10.3748\/wjg.v28.i3.365","volume":"28","author":"QH Sun","year":"2022","unstructured":"Sun QH, Zhang J, Shi YY, et al. Microbiome changes in the gastric mucosa and gastric juice in different histological stages of Helicobacter pylori-negative gastric cancers. World J Gastroenterol. 2022;28(3):365\u201380. https:\/\/doi.org\/10.3748\/wjg.v28.i3.365. PMID: 35110955; PMCID: PMC8771614.","journal-title":"World J Gastroenterol"},{"issue":"1","key":"3900_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1631\/jzus.B2100182","volume":"23","author":"Y Lu","year":"2022","unstructured":"Lu Y, Liu H, Mao Y, et al. A comprehensive update: Gastrointestinal microflora, gastric cancer and gastric premalignant condition, and intervention by traditional Chinese medicine. J Zhejiang Univ Sci B. 2022;23(1):1\u201318. https:\/\/doi.org\/10.1631\/jzus.B2100182. PMID: 35029085; PMCID: PMC8758937.","journal-title":"J Zhejiang Univ Sci B"},{"issue":"2","key":"3900_CR29","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.euo.2023.02.004","volume":"6","author":"L Bukavina","year":"2023","unstructured":"Bukavina L, Isali I, Ginwala R, et al. Global Meta-analysis of urine microbiome: colonization of polycyclic aromatic Hydrocarbon-degrading Bacteria among bladder Cancer patients. Eur Urol Oncol. 2023;6(2):190\u2013203. https:\/\/doi.org\/10.1016\/j.euo.2023.02.004. Epub 2023 Mar 1. PMID: 36868921.","journal-title":"Eur Urol Oncol"},{"key":"3900_CR30","doi-asserted-by":"publisher","first-page":"130608","DOI":"10.1016\/j.chemosphere.2021.130608","volume":"280","author":"N Premnath","year":"2021","unstructured":"Premnath N, Mohanrasu K, Guru Raj Rao R, et al. A crucial review on polycyclic aromatic Hydrocarbons-Environmental occurrence and strategies for microbial degradation. Chemosphere. 2021;280:130608. https:\/\/doi.org\/10.1016\/j.chemosphere.2021.130608. Epub 2021 Apr 28. PMID: 33962296.","journal-title":"Chemosphere"},{"key":"3900_CR31","doi-asserted-by":"publisher","first-page":"749207","DOI":"10.3389\/fcimb.2021.749207","volume":"11","author":"D Liu","year":"2021","unstructured":"Liu D, Chen S, Gou Y, et al. Gastrointestinal microbiota changes in patients with gastric precancerous lesions. Front Cell Infect Microbiol. 2021;11:749207. https:\/\/doi.org\/10.3389\/fcimb.2021.749207. PMID: 34956928; PMCID: PMC8695999.","journal-title":"Front Cell Infect Microbiol"},{"issue":"9","key":"3900_CR32","doi-asserted-by":"publisher","first-page":"1572","DOI":"10.1136\/gutjnl-2019-319826","volume":"69","author":"JJY Sung","year":"2020","unstructured":"Sung JJY, Coker OO, Chu E, et al. Gastric microbes associated with gastric inflammation, atrophy and intestinal metaplasia 1 year after Helicobacter pylori eradication. Gut. 2020;69(9):1572\u201380. https:\/\/doi.org\/10.1136\/gutjnl-2019-319826. Epub 2020 Jan 23. PMID: 31974133; PMCID: PMC7456733.","journal-title":"Gut"},{"key":"3900_CR33","doi-asserted-by":"publisher","first-page":"104711","DOI":"10.1016\/j.micpath.2020.104711","volume":"150","author":"HN Fan","year":"2021","unstructured":"Fan HN, Zhu P, Zhang J, et al. Mucosal Microbiome dysbiosis associated with duodenum bulb inflammation. Microb Pathog. 2021;150:104711. https:\/\/doi.org\/10.1016\/j.micpath.2020.104711. Epub 2020 Dec 29. PMID: 33385493.","journal-title":"Microb Pathog"},{"key":"3900_CR34","doi-asserted-by":"publisher","first-page":"20701","DOI":"10.1038\/srep20701","volume":"6","author":"CH Tseng","year":"2016","unstructured":"Tseng CH, Lin JT, Ho HJ, et al. Gastric microbiota and predicted gene functions are altered after subtotal gastrectomy in patients with gastric cancer. Sci Rep. 2016;6:20701. https:\/\/doi.org\/10.1038\/srep20701. PMID: 26860194; PMCID: PMC4748256.","journal-title":"Sci Rep"}],"container-title":["BMC Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12876-025-03900-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12876-025-03900-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12876-025-03900-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T07:57:26Z","timestamp":1745913446000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/10.1186\/s12876-025-03900-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,29]]},"references-count":34,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3900"],"URL":"https:\/\/doi.org\/10.1186\/s12876-025-03900-4","relation":{"references":[{"id-type":"doi","id":"10.1007\/s10620-020-06118-4","asserted-by":"subject"}]},"ISSN":["1471-230X"],"issn-type":[{"value":"1471-230X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,29]]},"assertion":[{"value":"28 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was conducted in accordance with the ethical principles of the Declaration of Helsinki (2013 version). The study protocol obtained prior approval from the Ethics Committee of Foshan Hospital of Traditional Chinese Medicine (Approval No. KY[2022]165). Written informed consent was obtained from all individual participants after they were fully informed about the study purpose, procedures, and potential risks (in accordance with Declaration of Helsinki paragraphs 15, 22\u201324).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"All sequencing results were submitted to NCBI with PRJNA1113136 (RUN37597816\u2013RUN37597852). This database is now accessible, allowing you to link to the website for inquiries ().","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Repositories"}}],"article-number":"304"}}