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Many elderly patients make severe mistakes which impede adequate drug delivery to the bronchioles. This multimodal training program was designed to reduce the number of handling mistakes of inhaler devices.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>From October 1, 2016 to September 30, 2017, a prospective intervention study was conducted in 38 in-patients <jats:underline>&gt;<\/jats:underline>\u200965\u2009years (median age 79\u2009years) with previously diagnosed COPD. The effect of an 8-day intervention comprising daily counselling and video demonstration according to the recommendations of the German Airway League on the frequency of mistakes during handling of inhaler devices, the forced expiratory volume in 1\u2009s (FEV1), the forced vital capacity (FVC) and the perception of symptoms (COPD Assessment Test, CAT) were studied. Measurements on days 1 and 8 were compared by Wilcoxon signed rank test.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The number of handling mistakes per patient decreased as a consequence of the intervention from 3.0 (0\u20137) to 0.5 (0\u20136) [median (minimum-maximum; <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.0001)]. The CAT Score decreased from 19.5 (14\/24) to 14.5 (10.75\/21) [median (25.\/75. percentile; <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.0001) indicating a substantial reduction of clinical symptoms. Conversely, FEV1 and FVC only slightly increased (difference statistically not significant). At study entry, the number of handling mistakes was inversely correlated with the Mini Mental Status Test (MMST) score (<jats:italic>p<\/jats:italic>\u00a0=\u20090.01). The reduction of the number of handling mistakes during the intervention was not correlated with the MMST.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>In COPD, intensive training for 8\u2009days improved the handling of inhalers and reduced clinical symptoms in geriatric patients. Patients with cognitive abnormalities also benefitted from this intervention.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Trial registration<\/jats:title>\n<jats:p>German Clinical Trials Registry <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.drks.de\/drks_web\/navigate.do?navigationId=trial.HTML&amp;TRIAL_ID=DRKS00023196\">DRKS00023196<\/jats:ext-link>, date of registration September 29, 2020 (retrospectively registered).<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s12877-020-01804-4","type":"journal-article","created":{"date-parts":[[2020,10,9]],"date-time":"2020-10-09T13:03:00Z","timestamp":1602248580000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Training improves the handling of inhaler devices and reduces the severity of symptoms in geriatric patients suffering from chronic-obstructive pulmonary disease"],"prefix":"10.1186","volume":"20","author":[{"given":"Marie-Christine","family":"Luley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Loleit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elmar","family":"Knopf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marija","family":"Djukic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl-Peter","family":"Cri\u00e9e","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8316-995X","authenticated-orcid":false,"given":"Roland","family":"Nau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,9]]},"reference":[{"key":"1804_CR1","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1016\/S0140-6736(07)61377-4","volume":"370","author":"AS Buist","year":"2007","unstructured":"Buist AS, McBurnie MA, Vollmer WM, Gillespie S, Burney P, Mannino DM, Menezes AM, Sullivan SD, Lee TA, Weiss KB. 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All patients gave their written informed consent to participate in this study. An overseeing mental health expert ruled that all adult patients and participants have been deemed capable of ethically and medically consenting for their participation in the research presented in this manuscript.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors declare that they have no commercial conflicts of interest\/competing interests in this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"398"}}