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The association between OH and, to a lesser extent, OHT with geriatric syndromes is controversial and little investigated.<\/jats:p>\n                <jats:p>Our objective was to assess the association between orthostatic blood pressure dysregulation and geriatric syndromes in an ambulatory outpatient population.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This observational study included all outpatients for whom a one-visit comprehensive geriatric assessment was performed during a year. OH was defined as a decrease of at least 20\u00a0mmHg in systolic blood pressure (SBP) and\/or 10\u00a0mmHg in diastolic blood pressure (DBP) after 1 or 3\u00a0min of standing. OHT was defined as an increase of more than 20\u00a0mmHg in SBP after 1 or 3\u00a0min of standing. Comorbidities, drugs regimen, a history of previous falls, nutritional, frailty, functional and cognitive status were compared between patients with OHT or OH and controls (NOR).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Five hundred thirty patients (mean age: 82.9\u2009\u00b1\u20095.1\u00a0years) were included. 19.6% had an OH and 22.3% an OHT. OHT patients were more frequently female, had more diabetes and a lower resting SBP than patients with NOR. OH patients had a higher resting SBP than NOR. After adjusting for age, sex, resting SBP and diabetes, OHT was associated with a low walking speed (OR\u2009=\u20091.332[1.009\u20131.758]; <jats:italic>p<\/jats:italic>\u2009=\u20090.043) and severe cognitive impairment at MMSe score (OR\u2009=\u20091.629[1.070\u20131.956]; <jats:italic>p<\/jats:italic>\u2009=\u20090.016) compared to NOR. Conversely, OH was associated with a lower grip strength (<jats:italic>p<\/jats:italic>\u2009=\u20090.016) than NOR.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>OHT and OH are common in elderly but associated with different geriatric phenotypes.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12877-022-02844-8","type":"journal-article","created":{"date-parts":[[2022,2,26]],"date-time":"2022-02-26T06:02:48Z","timestamp":1645855368000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Association between orthostatic blood pressure dysregulation and geriatric syndromes: a cross-sectional study"],"prefix":"10.1186","volume":"22","author":[{"given":"Fr\u00e9d\u00e9ric","family":"Roca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Rougette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Zmuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle","family":"Noel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sol\u00e8ne","family":"Larose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Bordage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Chassagne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,2,26]]},"reference":[{"key":"2844_CR1","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1161\/CIRCULATIONAHA.105.598722","volume":"114","author":"KM Rose","year":"2006","unstructured":"Rose KM, Eigenbrodt ML, Biga RL, Couper DJ, Light KC, Sharrett AR, et al. 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Curr Hypertens Rep. 2017;19:24.","journal-title":"Curr Hypertens Rep"}],"container-title":["BMC Geriatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12877-022-02844-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12877-022-02844-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12877-022-02844-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,26]],"date-time":"2022-02-26T06:03:36Z","timestamp":1645855416000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgeriatr.biomedcentral.com\/articles\/10.1186\/s12877-022-02844-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,26]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["2844"],"URL":"https:\/\/doi.org\/10.1186\/s12877-022-02844-8","relation":{},"ISSN":["1471-2318"],"issn-type":[{"value":"1471-2318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,26]]},"assertion":[{"value":"20 June 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 January 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 February 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the Rouen University Hospital local ethic committee (\u201cCommission de qualification du CHU de ROUEN\u201d) and was registered under the identification number 2018\/0414\/OB. Patients was informed that their personal data could be used for research and verbal informed consent was obtained in accordance with the French legislation. This verbal informed consent was approved by our local ethic committee (\u201cCommission de qualification du CHU de ROUEN\u201d). According to the French Jard\u00e9\u2019s Law about non interventional research, only verbal informed consent is necessary when the research is performed on medical records. In case of opposition, patient\u2019s data were not included in the study. All methods were carried out in accordance with relevant guidelines and regulations (declaration of Helsinki).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"157"}}