{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:28:23Z","timestamp":1787020103636,"version":"build-2736575974"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T00:00:00Z","timestamp":1706572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T00:00:00Z","timestamp":1706572800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Geriatr"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Iron deficiency (ID) is often associated with other comorbidities in older patients and is a factor of morbimortality. However, the prevalence of ID remains poorly documented in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The CARENFER PA study was a French multicenter cross-sectional study whose objective was to evaluate ID in patients (&gt;\u200975\u00a0years) admitted to a geriatric unit. The primary endpoint was the ID prevalence defined as: serum ferritin\u2009&lt;\u2009100\u00a0\u00b5g\/L and\/or transferrin saturation coefficient (TSAT)\u2009&lt;\u200920%. The Short Physical Performance Battery (SPPB) test was used to identify older patients at high risk of adverse events (e.g., disability, falls, hospitalization, death).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 888 patients (mean age, 85.2\u00a0years; women, 63.5%) from 16 French centers were included from October 2022 to December 2022. The prevalence of ID was 57.6% (95% CI, 54.3\u201360.9) in the cohort of older patients (62.6% in anemic and 53.3% in non-anemic patients;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0062). ID prevalence increased significantly with the presence of more than three comorbidities (65.6% vs. 55.9%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0274), CRP\u2009\u2265\u200912\u00a0mg\/L (73.0% vs. 49.3%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and treatment that may influence ID\/anemia (60.5% vs. 49.6%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0042). In multivariate analysis, only CRP\u2009\u2265\u200912\u00a0mg\/L was an independent predictive factor of ID (odds ratio, 2.78; 95% CI, 1.92\u20134.08;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). SPPB scores were low (0\u20136) in 60.5% of patients with ID versus 48.6% of patients without ID (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0076).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>More than half of older patients had ID, including non-anemic patients. ID was associated with the presence of inflammation and a low SPPB score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>NCT05514951.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12877-024-04719-6","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T20:02:51Z","timestamp":1706558571000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Prevalence of iron deficiency in patients admitted to a geriatric unit: a multicenter cross-sectional study"],"prefix":"10.1186","volume":"24","author":[{"given":"Bertrand","family":"Foug\u00e8re","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Puisieux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Chevalet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9dric","family":"Annweiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emeline","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Joly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Blanc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelghani EL","family":"Azouzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Desr\u00e9-Follet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrice","family":"Cacoub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the CARENFER PA study group*","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Sophie","family":"Billet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florent","family":"Fiasson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Garnier-Crussard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Goidin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Paccalin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Parnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikel","family":"Sarasibar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,30]]},"reference":[{"key":"4719_CR1","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1182\/blood-2018-05-815944","volume":"133","author":"C Camaschella","year":"2019","unstructured":"Camaschella C. 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El Azouzi: no conflict of interest.V. Desr\u00e9-Follet: employee of CSL Vifor, France.P. Cacoub: consultancies, honoraria, advisory board, speakers\u2019 fees: Alnylam, Innotech, Mylan, Pfizer, Servier, and Vifor.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"112"}}