{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T02:29:48Z","timestamp":1787884188665,"version":"build-2784847793"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T00:00:00Z","timestamp":1764892800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T00:00:00Z","timestamp":1764892800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"the Discipline Promotion Programme of Shanghai Fourth People\u2019s Hospital","award":["SY-XKZT-2024-2003"],"award-info":[{"award-number":["SY-XKZT-2024-2003"]}]},{"name":"the Discipline Promotion Programme of Shanghai Fourth People\u2019s Hospital","award":["SY-XKZT-2020-1010"],"award-info":[{"award-number":["SY-XKZT-2020-1010"]}]},{"name":"Startup Foundation for Scientific Research of Shanghai Fourth People\u2019s Hospital","award":["sykyqd01601"],"award-info":[{"award-number":["sykyqd01601"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Geriatr"],"DOI":"10.1186\/s12877-025-06546-9","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T13:45:25Z","timestamp":1764942325000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Associations of high protein supplements with gut microbiota and skeletal muscle mass in hospitalized older people"],"prefix":"10.1186","volume":"25","author":[{"given":"Ying","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuezhu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Ran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueneng","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongqiang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huajun","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,5]]},"reference":[{"issue":"6","key":"6546_CR1","doi-asserted-by":"crossref","first-page":"2586","DOI":"10.1002\/jcsm.13602","volume":"15","author":"DAM Saez","year":"2024","unstructured":"Saez DAM, Martinez-Velilla N, Zambom-Ferraresi F, et al. Short-Term multicomponent exercise impact on muscle function and structure in hospitalized older at risk of acute Sarcopenia[J]. J Cachexia Sarcopenia Muscle. 2024;15(6):2586\u201394.","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"2","key":"6546_CR2","doi-asserted-by":"crossref","first-page":"465","DOI":"10.3945\/ajcn.115.112359","volume":"103","author":"KL English","year":"2016","unstructured":"English KL, Mettler JA, Ellison JB, et al. Leucine partially protects muscle mass and function during bed rest in middle-aged adults[J]. Am J Clin Nutr. 2016;103(2):465\u201373.","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"6546_CR3","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/ageing\/afy169","volume":"48","author":"AJ Cruz-Jentoft","year":"2019","unstructured":"Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis[J]. Age Ageing. 2019;48(1):16\u201331.","journal-title":"Age Ageing"},{"issue":"1","key":"6546_CR4","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1017\/S0029665113003698","volume":"73","author":"AA Welch","year":"2014","unstructured":"Welch AA. Nutritional influences on age-related skeletal muscle loss[J]. Proc Nutr Soc. 2014;73(1):16\u201333.","journal-title":"Proc Nutr Soc"},{"issue":"1","key":"6546_CR5","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1152\/japplphysiol.00363.2020","volume":"131","author":"U Marusic","year":"2021","unstructured":"Marusic U, Narici M, Simunic B, et al. Nonuniform loss of muscle strength and atrophy during bed rest: a systematic review[J]. J Appl Physiol (1985). 2021;131(1):194\u2013206.","journal-title":"J Appl Physiol (1985)"},{"issue":"4","key":"6546_CR6","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1152\/japplphysiol.00847.2019","volume":"128","author":"EJ Arentson-Lantz","year":"2020","unstructured":"Arentson-Lantz EJ, Fiebig KN, Anderson-Catania KJ, et al. Countering disuse atrophy in older adults with low-volume leucine supplementation[J]. J Appl Physiol (1985). 2020;128(4):967\u201377.","journal-title":"J Appl Physiol (1985)"},{"issue":"3","key":"6546_CR7","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.clnu.2020.08.017","volume":"40","author":"CC Lin","year":"2021","unstructured":"Lin CC, Shih MH, Chen CD, et al. Effects of adequate dietary protein with Whey protein, leucine, and vitamin D supplementation on sarcopenia in older adults: an open-label, parallel-group study[J]. Clin Nutr. 2021;40(3):1323\u20139.","journal-title":"Clin Nutr"},{"issue":"5","key":"6546_CR8","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1093\/ajcn\/nqy214","volume":"108","author":"Y Park","year":"2018","unstructured":"Park Y, Choi JE, Hwang HS. Protein supplementation improves muscle mass and physical performance in undernourished prefrail and frail elderly subjects: a randomized, double-blind, placebo-controlled trial[J]. Am J Clin Nutr. 2018;108(5):1026\u201333.","journal-title":"Am J Clin Nutr"},{"issue":"5","key":"6546_CR9","doi-asserted-by":"crossref","first-page":"997","DOI":"10.3945\/ajcn.110.008102","volume":"93","author":"B Pennings","year":"2011","unstructured":"Pennings B, Boirie Y, Senden JM, et al. Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men[J]. Am J Clin Nutr. 2011;93(5):997\u20131005.","journal-title":"Am J Clin Nutr"},{"key":"6546_CR10","doi-asserted-by":"crossref","unstructured":"Trommelen J, Weijzen M, van Kranenburg J et al. Casein protein processing strongly modulates Post-Prandial plasma amino acid responses in vivo in Humans[J]. Nutrients, 2020,12(8).","DOI":"10.3390\/nu12082299"},{"issue":"26","key":"6546_CR11","doi-asserted-by":"crossref","first-page":"14930","DOI":"10.1073\/pnas.94.26.14930","volume":"94","author":"Y Boirie","year":"1997","unstructured":"Boirie Y, Dangin M, Gachon P, et al. Slow and fast dietary proteins differently modulate postprandial protein accretion[J]. Proc Natl Acad Sci U S A. 1997;94(26):14930\u20135.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6","key":"6546_CR12","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1002\/jcsm.12784","volume":"12","author":"C Liu","year":"2021","unstructured":"Liu C, Cheung WH, Li J, et al. Understanding the gut microbiota and sarcopenia: a systematic review[J]. J Cachexia Sarcopenia Muscle. 2021;12(6):1393\u2013407.","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"5","key":"6546_CR13","first-page":"100479","volume":"4","author":"S Chen","year":"2023","unstructured":"Chen S, Zhang P, Duan H, et al. Gut microbiota in muscular atrophy development, progression, and treatment: new therapeutic targets and opportunities[J]. Innov (Camb). 2023;4(5):100479.","journal-title":"Innov (Camb)"},{"key":"6546_CR14","doi-asserted-by":"crossref","first-page":"101739","DOI":"10.1016\/j.arr.2022.101739","volume":"81","author":"T Zhang","year":"2022","unstructured":"Zhang T, Cheng JK, Hu YM. Gut microbiota as a promising therapeutic target for age-related sarcopenia[J]. Ageing Res Rev. 2022;81:101739.","journal-title":"Ageing Res Rev"},{"issue":"1","key":"6546_CR15","doi-asserted-by":"crossref","first-page":"4","DOI":"10.4161\/gmic.19320","volume":"3","author":"HJ Wu","year":"2012","unstructured":"Wu HJ, Wu E. The role of gut microbiota in immune homeostasis and autoimmunity[J]. Gut Microbes. 2012;3(1):4\u201314.","journal-title":"Gut Microbes"},{"issue":"3","key":"6546_CR16","doi-asserted-by":"crossref","first-page":"830","DOI":"10.3945\/ajcn.115.113357","volume":"103","author":"M Rondanelli","year":"2016","unstructured":"Rondanelli M, Klersy C, Terracol G, et al. Whey protein, amino acids, and vitamin D supplementation with physical activity increases fat-free mass and strength, functionality, and quality of life and decreases inflammation in sarcopenic elderly[J]. Am J Clin Nutr. 2016;103(3):830\u201340.","journal-title":"Am J Clin Nutr"},{"issue":"3","key":"6546_CR17","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jamda.2019.12.012","volume":"21","author":"LK Chen","year":"2020","unstructured":"Chen LK, Woo J, Assantachai P, et al. Asian working group for sarcopenia: 2019 consensus update on sarcopenia diagnosis and Treatment[J]. J Am Med Dir Assoc. 2020;21(3):300\u20137.","journal-title":"J Am Med Dir Assoc"},{"key":"6546_CR18","doi-asserted-by":"crossref","first-page":"2890","DOI":"10.3389\/fmicb.2018.02890","volume":"9","author":"J Bao","year":"2018","unstructured":"Bao J, Zheng H, Wang Y, et al. Echinococcus granulosus infection results in an increase in Eisenbergiella and parabacteroides genera in the gut of Mice[J]. Front Microbiol. 2018;9:2890.","journal-title":"Front Microbiol"},{"issue":"5","key":"6546_CR19","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1152\/japplphysiol.91351.2008","volume":"106","author":"NA Burd","year":"2009","unstructured":"Burd NA, Tang JE, Moore DR, et al. Exercise training and protein metabolism: influences of contraction, protein intake, and sex-based differences[J]. J Appl Physiol (1985). 2009;106(5):1692\u2013701.","journal-title":"J Appl Physiol (1985)"},{"key":"6546_CR20","doi-asserted-by":"crossref","unstructured":"Liao CD, Huang SW, Chen HC et al. Comparative efficacy of different protein supplements on muscle Mass, Strength, and physical indices of sarcopenia among Community-Dwelling, hospitalized or institutionalized older adults undergoing resistance training: A network Meta-Analysis of randomized controlled Trials[J]. Nutrients, 2024,16(7).","DOI":"10.3390\/nu16070941"},{"key":"6546_CR21","doi-asserted-by":"crossref","unstructured":"Cereda E, Pisati R, Rondanelli M et al. Whey Protein, Leucine- and Vitamin-D-Enriched oral nutritional supplementation for the treatment of Sarcopenia[J]. Nutrients, 2022,14(7).","DOI":"10.3390\/nu14071524"},{"issue":"1","key":"6546_CR22","first-page":"37","volume":"21","author":"Y Boirie","year":"2018","unstructured":"Boirie Y, Guillet C. Fast digestive proteins and sarcopenia of aging[J]. Curr Opin Clin Nutr Metab Care. 2018;21(1):37\u201341.","journal-title":"Curr Opin Clin Nutr Metab Care"},{"issue":"8","key":"6546_CR23","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1093\/jn\/nxaa024","volume":"150","author":"S Gorissen","year":"2020","unstructured":"Gorissen S, Trommelen J, Kouw I, et al. Protein Type, protein Dose, and age modulate dietary protein digestion and phenylalanine absorption kinetics and plasma phenylalanine availability in Humans[J]. J Nutr. 2020;150(8):2041\u201350.","journal-title":"J Nutr"},{"key":"6546_CR24","doi-asserted-by":"crossref","unstructured":"Zanini B, Simonetto A, Zubani M et al. The effects of Cow-Milk protein supplementation in elderly population: systematic review and narrative Synthesis[J]. Nutrients, 2020,12(9).","DOI":"10.3390\/nu12092548"},{"issue":"2","key":"6546_CR25","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1093\/jn\/nxy244","volume":"149","author":"TA Churchward-Venne","year":"2019","unstructured":"Churchward-Venne TA, Pinckaers P, Smeets J, et al. Myofibrillar and mitochondrial protein synthesis rates do not differ in young men following the ingestion of carbohydrate with milk protein, Whey, or micellar casein after concurrent Resistance- and Endurance-Type Exercise[J]. J Nutr. 2019;149(2):198\u2013209.","journal-title":"J Nutr"},{"issue":"1","key":"6546_CR26","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1093\/gerona\/glu103","volume":"70","author":"DR Moore","year":"2015","unstructured":"Moore DR, Churchward-Venne TA, Witard O, et al. Protein ingestion to stimulate myofibrillar protein synthesis requires greater relative protein intakes in healthy older versus younger men[J]. J Gerontol Biol Sci Med Sci. 2015;70(1):57\u201362.","journal-title":"J Gerontol Biol Sci Med Sci"},{"issue":"5","key":"6546_CR27","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1002\/jcsm.13541","volume":"15","author":"YX Luo","year":"2024","unstructured":"Luo YX, Zhou XH, Heng T, et al. Bidirectional transitions of sarcopenia States in older adults: the longitudinal evidence from CHARLS[J]. J Cachexia Sarcopenia Muscle. 2024;15(5):1915\u201329.","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"6546_CR28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.nut.2018.11.020","volume":"62","author":"D Spira","year":"2019","unstructured":"Spira D, Buchmann N, Konig M, et al. Sex-specific differences in the association of vitamin D with low lean mass and frailty: results from the Berlin aging study II[J]. Nutrition. 2019;62:1\u20136.","journal-title":"Nutrition"},{"issue":"1","key":"6546_CR29","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1186\/s12877-022-03577-4","volume":"22","author":"S Jia","year":"2022","unstructured":"Jia S, Zhao W, Hu F, et al. Sex differences in the association of physical activity levels and vitamin D with obesity, sarcopenia, and sarcopenic obesity: a cross-sectional study[J]. BMC Geriatr. 2022;22(1):898.","journal-title":"BMC Geriatr"},{"issue":"4","key":"6546_CR30","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1002\/jcsm.13498","volume":"15","author":"M Midttun","year":"2024","unstructured":"Midttun M, Overgaard K, Zerahn B, et al. Beneficial effects of exercise, testosterone, vitamin D, calcium and protein in older men-A randomized clinical trial[J]. J Cachexia Sarcopenia Muscle. 2024;15(4):1451\u201362.","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"8","key":"6546_CR31","doi-asserted-by":"crossref","first-page":"4077","DOI":"10.1007\/s00394-022-02941-9","volume":"61","author":"L Chen","year":"2022","unstructured":"Chen L, Ming J, Chen T, et al. Association between dietary inflammatory index score and muscle mass and strength in older adults: a study from National health and nutrition examination survey (NHANES) 1999\u20132002[J]. Eur J Nutr. 2022;61(8):4077\u201389.","journal-title":"Eur J Nutr"},{"key":"6546_CR32","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jot.2017.05.006","volume":"10","author":"J Wang","year":"2017","unstructured":"Wang J, Leung KS, Chow SK, et al. Inflammation and age-associated skeletal muscle deterioration (sarcopaenia)[J]. J Orthop Translat. 2017;10:94\u2013101.","journal-title":"J Orthop Translat"},{"issue":"3","key":"6546_CR33","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.gerinurse.2014.02.001","volume":"35","author":"CH Wang","year":"2014","unstructured":"Wang CH, Chung MH, Chan P, et al. Effects of endurance exercise training on risk components for metabolic syndrome, interleukin-6, and the exercise capacity of postmenopausal women[J]. Geriatr Nurs. 2014;35(3):212\u20138.","journal-title":"Geriatr Nurs"},{"key":"6546_CR34","doi-asserted-by":"crossref","unstructured":"Remelli F, Vitali A, Zurlo A et al. Vitamin D deficiency and sarcopenia in older Persons[J]. Nutrients, 2019,11(12).","DOI":"10.3390\/nu11122861"},{"key":"6546_CR35","doi-asserted-by":"crossref","unstructured":"Granic A, Hill TR, Davies K et al. Vitamin D Status, muscle strength and physical performance decline in very old adults: A prospective Study[J]. Nutrients, 2017,9(4).","DOI":"10.3390\/nu9040379"},{"key":"6546_CR36","doi-asserted-by":"crossref","unstructured":"Wang H, Lv X, Zhao S et al. Weight loss promotion in individuals with obesity through gut microbiota alterations with a multiphase modified ketogenic Diet[J]. Nutrients, 2023,15(19).","DOI":"10.3390\/nu15194163"},{"issue":"1","key":"6546_CR37","doi-asserted-by":"crossref","first-page":"4477","DOI":"10.1038\/s41467-022-32015-7","volume":"13","author":"K Hosomi","year":"2022","unstructured":"Hosomi K, Saito M, Park J, et al. Oral administration of blautia Wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota[J]. Nat Commun. 2022;13(1):4477.","journal-title":"Nat Commun"},{"issue":"1","key":"6546_CR38","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.cell.2020.08.039","volume":"183","author":"A Reddy","year":"2020","unstructured":"Reddy A, Bozi L, Yaghi OK, et al. pH-Gated succinate secretion regulates muscle remodeling in response to Exercise[J]. Cell. 2020;183(1):62\u201375.","journal-title":"Cell"},{"issue":"1","key":"6546_CR39","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1038\/s41467-024-45636-x","volume":"15","author":"Y Zhang","year":"2024","unstructured":"Zhang Y, Tu S, Ji X, et al. Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway[J]. Nat Commun. 2024;15(1):1333.","journal-title":"Nat Commun"},{"issue":"9","key":"6546_CR40","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1099\/mic.0.000515","volume":"163","author":"D Hatziioanou","year":"2017","unstructured":"Hatziioanou D, Gherghisan-Filip C, Saalbach G, et al. Discovery of a novel lantibiotic Nisin O from blautia obeum A2-162, isolated from the human Gastrointestinal tract[J]. Microbiol (Reading). 2017;163(9):1292\u2013305.","journal-title":"Microbiol (Reading)"},{"issue":"10","key":"6546_CR41","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1136\/gutjnl-2018-317842","volume":"68","author":"BH Mullish","year":"2019","unstructured":"Mullish BH, McDonald J, Pechlivanis A, et al. Microbial bile salt hydrolases mediate the efficacy of faecal microbiota transplant in the treatment of recurrent clostridioides difficile infection[J]. Gut. 2019;68(10):1791\u2013800.","journal-title":"Gut"},{"issue":"1","key":"6546_CR42","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1186\/s40001-023-01432-9","volume":"28","author":"MJ Fernandez-Cotarelo","year":"2023","unstructured":"Fernandez-Cotarelo MJ, Jackson-Akers JY, Nagy-Agren SE, et al. Interaction of clostridioides difficile infection with frailty and cognition in the elderly: a narrative review[J]. Eur J Med Res. 2023;28(1):439.","journal-title":"Eur J Med Res"},{"issue":"6","key":"6546_CR43","first-page":"e253122","volume":"10","author":"SW Ryu","year":"2022","unstructured":"Ryu SW, Kim JS, Oh BS, et al. Gut microbiota Eubacterium callanderi exerts Anti-Colorectal cancer Activity[J]. Microbiol Spectr. 2022;10(6):e253122.","journal-title":"Microbiol Spectr"},{"issue":"3","key":"6546_CR44","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.aninu.2015.08.008","volume":"1","author":"M Watford","year":"2015","unstructured":"Watford M. Glutamine and glutamate: nonessential or essential amino acids?[J]. Anim Nutr. 2015;1(3):119\u201322.","journal-title":"Anim Nutr"},{"key":"6546_CR45","doi-asserted-by":"crossref","unstructured":"Wang X, Zong X, Ye M et al. Lysine distinctively manipulates myogenic regulatory factors and Wnt\/Ca(2+) pathway in slow and fast Muscles, and their satellite cells of postnatal Piglets[J]. Cells, 2024,13(7).","DOI":"10.3390\/cells13070650"},{"issue":"11","key":"6546_CR46","doi-asserted-by":"crossref","first-page":"e12891","DOI":"10.1111\/cpr.12891","volume":"53","author":"Y Ouyang","year":"2020","unstructured":"Ouyang Y, Wu Q, Li J, et al. S-adenosylmethionine: A metabolite critical to the regulation of autophagy[J]. Cell Prolif. 2020;53(11):e12891.","journal-title":"Cell Prolif"},{"key":"6546_CR47","doi-asserted-by":"crossref","unstructured":"Valentim MA, Brahmbhatt AN, Tupling AR. Skeletal and cardiac muscle calcium transport regulation in health and disease[J]. Biosci Rep, 2022,42(12).","DOI":"10.1042\/BSR20211997"},{"issue":"4","key":"6546_CR48","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1210\/er.2017-00246","volume":"39","author":"JW Rich-Edwards","year":"2018","unstructured":"Rich-Edwards JW, Kaiser UB, Chen GL, et al. Sex and gender differences research design for Basic, Clinical, and population studies: essentials for Investigators[J]. Endocr Rev. 2018;39(4):424\u201339.","journal-title":"Endocr Rev"},{"issue":"1","key":"6546_CR49","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1186\/s12877-022-03019-1","volume":"22","author":"Y Huh","year":"2022","unstructured":"Huh Y, Son KY. Association between total protein intake and low muscle mass in Korean adults[J]. BMC Geriatr. 2022;22(1):319.","journal-title":"BMC Geriatr"},{"issue":"1","key":"6546_CR50","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1093\/ajcn\/87.1.150","volume":"87","author":"DK Houston","year":"2008","unstructured":"Houston DK, Nicklas BJ, Ding J, et al. Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and body composition (Health ABC) Study[J]. Am J Clin Nutr. 2008;87(1):150\u20135.","journal-title":"Am J Clin Nutr"}],"container-title":["BMC Geriatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12877-025-06546-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12877-025-06546-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12877-025-06546-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T08:26:53Z","timestamp":1771403213000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12877-025-06546-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,5]]},"references-count":50,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["6546"],"URL":"https:\/\/doi.org\/10.1186\/s12877-025-06546-9","relation":{},"ISSN":["1471-2318"],"issn-type":[{"value":"1471-2318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,5]]},"assertion":[{"value":"12 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 February 2026","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The original online version of this article was revised: Ying Chen and Yuezhu Wang should have been denoted as equally contributing authors.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was conducted in accordance with the principles of the Helsinki Declaration and approved by ethics committee of Shanghai Fourth People\u2019s Hospital (2021114-001). Informed consent was obtained from all individual participants included in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval\u00a0<!--Emphasis Type='Bold' removed-->and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"998"}}