{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T11:10:54Z","timestamp":1772190654287,"version":"3.50.1"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:00:00Z","timestamp":1769817600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Geriatr"],"DOI":"10.1186\/s12877-026-07087-5","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T12:46:13Z","timestamp":1769863573000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Construction and validation of a diagnostic model for acute suppurative cholecystitis in older patients: LASSO-Logistic regression analysis using readily available clinical indicators"],"prefix":"10.1186","volume":"26","author":[{"given":"Hong-Yu","family":"Long","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo-Dong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bai-Qing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,31]]},"reference":[{"key":"7087_CR1","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s12875-023-01964-3","volume":"24","author":"E Escourrou","year":"2023","unstructured":"Escourrou E, Joyeux T, Guilhem M, et al. How general practitioners perceive the aging trajectory of oldest-old - A qualitative study. BMC Prim Care. 2023;24:5. https:\/\/doi.org\/10.1186\/s12875-023-01964-3.","journal-title":"BMC Prim Care"},{"key":"7087_CR2","doi-asserted-by":"publisher","first-page":"735","DOI":"10.21037\/atm-21-6186","volume":"10","author":"Y Song","year":"2022","unstructured":"Song Y, Ma Y, Xie F-C, et al. Age, gender, geographic and clinical differences for gallstones in china: a nationwide study. Ann Transl Med. 2022;10:735. https:\/\/doi.org\/10.21037\/atm-21-6186.","journal-title":"Ann Transl Med"},{"key":"7087_CR3","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/s13017-019-0224-7","volume":"14","author":"M Pisano","year":"2019","unstructured":"Pisano M, Ceresoli M, Cimbanassi S, et al. 2017 WSES and SICG guidelines on acute calcolous cholecystitis in elderly population. World J Emerg Surg. 2019;14:10. https:\/\/doi.org\/10.1186\/s13017-019-0224-7.","journal-title":"World J Emerg Surg"},{"key":"7087_CR4","doi-asserted-by":"publisher","first-page":"4078","DOI":"10.1007\/s00464-018-6092-5","volume":"32","author":"T Wiggins","year":"2018","unstructured":"Wiggins T, Markar SR, Mackenzie H, et al. Evolution in the management of acute cholecystitis in the elderly: population-based cohort study. Surg Endosc. 2018;32:4078\u201386. https:\/\/doi.org\/10.1007\/s00464-018-6092-5.","journal-title":"Surg Endosc"},{"key":"7087_CR5","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1001\/jama.2022.2350","volume":"327","author":"JR Gallaher","year":"2022","unstructured":"Gallaher JR, Charles A. Acute cholecystitis: A review. JAMA. 2022;327:965\u201375. https:\/\/doi.org\/10.1001\/jama.2022.2350.","journal-title":"JAMA"},{"key":"7087_CR6","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.pain.2006.12.009","volume":"129","author":"J \u017byczkowska","year":"2007","unstructured":"\u017byczkowska J, Szczerbi\u0144ska K, Jantzi MR, Hirdes JP. Pain among the oldest old in community and institutional settings. Pain. 2007;129:167\u201376. https:\/\/doi.org\/10.1016\/j.pain.2006.12.009.","journal-title":"Pain"},{"key":"7087_CR7","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1002\/jhbp.515","volume":"25","author":"M Yokoe","year":"2018","unstructured":"Yokoe M, Hata J, Takada T, et al. Tokyo guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepato-Biliary-Pancreat Sci. 2018;25:41\u201354. https:\/\/doi.org\/10.1002\/jhbp.515.","journal-title":"J Hepato-Biliary-Pancreat Sci"},{"key":"7087_CR8","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1002\/jhbp.516","volume":"25","author":"K Okamoto","year":"2018","unstructured":"Okamoto K, Suzuki K, Takada T, et al. Tokyo guidelines 2018: flowchart for the management of acute cholecystitis. J Hepato-Biliary-Pancreat Sci. 2018;25:55\u201372. https:\/\/doi.org\/10.1002\/jhbp.516.","journal-title":"J Hepato-Biliary-Pancreat Sci"},{"key":"7087_CR9","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1007\/s00464-018-6281-2","volume":"33","author":"EA Griffiths","year":"2019","unstructured":"Griffiths EA, Hodson J, Vohra RS, et al. Utilisation of an operative difficulty grading scale for laparoscopic cholecystectomy. Surg Endosc. 2019;33:110\u201321. https:\/\/doi.org\/10.1007\/s00464-018-6281-2.","journal-title":"Surg Endosc"},{"key":"7087_CR10","doi-asserted-by":"publisher","first-page":"5434","DOI":"10.1007\/s00261-021-03160-2","volume":"46","author":"D Lee","year":"2021","unstructured":"Lee D, Appel S, Nunes L. CT findings and outcomes of acute cholecystitis: is additional ultrasound necessary? Abdom Radiol. 2021;46:5434\u201342. https:\/\/doi.org\/10.1007\/s00261-021-03160-2.","journal-title":"Abdom Radiol"},{"key":"7087_CR11","doi-asserted-by":"publisher","first-page":"6447","DOI":"10.1007\/s00330-019-06258-w","volume":"29","author":"JH Min","year":"2019","unstructured":"Min JH, Shin KS, Lee JE, et al. Combination of CT findings can reliably predict radiolucent common bile duct stones: a novel approach using a CT-based nomogram. Eur Radiol. 2019;29:6447\u201357. https:\/\/doi.org\/10.1007\/s00330-019-06258-w.","journal-title":"Eur Radiol"},{"key":"7087_CR12","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.23.30037","author":"M Js","year":"2024","unstructured":"Js M, Rj M. Risk of acute kidney injury following IV iodinated contrast media exposure: 2023 Update, from the AJR special series on contrast media. AJR Am J Roentgenol. 2024;223. https:\/\/doi.org\/10.2214\/AJR.23.30037.","journal-title":"AJR Am J Roentgenol"},{"key":"7087_CR13","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.ejrad.2019.03.008","volume":"116","author":"A-L Faucon","year":"2019","unstructured":"Faucon A-L, Bobrie G, Cl\u00e9ment O. Nephrotoxicity of iodinated contrast media: from pathophysiology to prevention strategies. Eur J Radiol. 2019;116:231\u201341. https:\/\/doi.org\/10.1016\/j.ejrad.2019.03.008.","journal-title":"Eur J Radiol"},{"key":"7087_CR14","doi-asserted-by":"publisher","unstructured":"Fanciulli G, Favara G, Maugeri A, et al. Comparing percutaneous treatment and cholecystectomy outcomes in acute cholecystitis patients: a systematic review and meta-analysis. World J Emerg Surg. 2025;20. https:\/\/doi.org\/10.1186\/s13017-025-00622-6.","DOI":"10.1186\/s13017-025-00622-6"},{"key":"7087_CR15","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1001\/jamasurg.2025.0729","volume":"160","author":"RC Acker","year":"2025","unstructured":"Acker RC, Ginzberg SP, Sharpe J, et al. Operative vs nonoperative treatment of acute cholecystitis in older adults with Multimorbidity. JAMA Surg. 2025;160:656\u201364. https:\/\/doi.org\/10.1001\/jamasurg.2025.0729.","journal-title":"JAMA Surg"},{"key":"7087_CR16","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1186\/s12876-022-02224-x","volume":"22","author":"B-Q Chen","year":"2022","unstructured":"Chen B-Q, Xie F, Chen G-D, et al. Value of nonenhanced CT combined with laboratory examinations in the diagnosis of acute suppurative cholecystitis treated with percutaneous cholecystostomy: a retrospective study. BMC Gastroenterol. 2022;22:155. https:\/\/doi.org\/10.1186\/s12876-022-02224-x.","journal-title":"BMC Gastroenterol"},{"key":"7087_CR17","doi-asserted-by":"publisher","first-page":"4765","DOI":"10.48550\/arXiv.1705.07874","volume":"30","author":"SM Lundberg","year":"2017","unstructured":"Lundberg SM, Lee SI. A unified approach to interpreting model predictions. Adv Neural Inf Process Syst. 2017;30:4765\u201374. https:\/\/doi.org\/10.48550\/arXiv.1705.07874.","journal-title":"Adv Neural Inf Process Syst"},{"key":"7087_CR18","doi-asserted-by":"publisher","first-page":"595","DOI":"10.3390\/pr11020595","volume":"11","author":"TAA Abdullah","year":"2023","unstructured":"Abdullah TAA, Zahid MSM, Ali W, Ul Hassan S. B-LIME: an improvement of LIME for interpretable deep learning classification of cardiac arrhythmia from ECG signals. PROCESSES. 2023;11:595. https:\/\/doi.org\/10.3390\/pr11020595.","journal-title":"PROCESSES"},{"key":"7087_CR19","doi-asserted-by":"publisher","first-page":"52641","DOI":"10.1109\/ACCESS.2024.3384277","volume":"12","author":"TAA Abdullah","year":"2024","unstructured":"Abdullah TAA, Zahid MSM, Turki AF, et al. Sig-Lime: A Signal-Based enhancement of lime explanation technique. IEEE ACCESS. 2024;12:52641\u201358. https:\/\/doi.org\/10.1109\/ACCESS.2024.3384277.","journal-title":"IEEE ACCESS"},{"key":"7087_CR20","doi-asserted-by":"publisher","first-page":"109569","DOI":"10.1016\/j.compbiomed.2024.109569","volume":"185","author":"SU Hassan","year":"2025","unstructured":"Hassan SU, Abdulkadir SJ, Zahid MSM, Al-Selwi SM. Local interpretable model-agnostic explanation approach for medical imaging analysis: A systematic literature review. Comput Biol Med. 2025;185:109569. https:\/\/doi.org\/10.1016\/j.compbiomed.2024.109569.","journal-title":"Comput Biol Med"},{"key":"7087_CR21","doi-asserted-by":"publisher","first-page":"5282","DOI":"10.3748\/wjg.14.5282","volume":"14","author":"D Festi","year":"2008","unstructured":"Festi D, Dormi A, Capodicasa S, et al. Incidence of gallstone disease in italy: results from a multicenter, population-based Italian study (the MICOL project). World J Gastroenterol. 2008;14:5282. https:\/\/doi.org\/10.3748\/wjg.14.5282.","journal-title":"World J Gastroenterol"},{"key":"7087_CR22","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.2214\/AJR.09.3640","volume":"194","author":"JS Shakespear","year":"2010","unstructured":"Shakespear JS, Shaaban AM, Rezvani M. CT findings of acute cholecystitis and its complications. AJR Am J Roentgenol. 2010;194:1523\u20139. https:\/\/doi.org\/10.2214\/AJR.09.3640.","journal-title":"AJR Am J Roentgenol"},{"key":"7087_CR23","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1007\/s40520-015-0361-0","volume":"27","author":"PC Ambe","year":"2015","unstructured":"Ambe PC, Weber SA, Christ H, Wassenberg D. Primary cholecystectomy is feasible in elderly patients with acute cholecystitis. Aging Clin Exp Res. 2015;27:921\u20136. https:\/\/doi.org\/10.1007\/s40520-015-0361-0.","journal-title":"Aging Clin Exp Res"},{"key":"7087_CR24","doi-asserted-by":"publisher","unstructured":"Canakis A, Tugarinov N, Deliwala S, et al. Clinical outcomes of EUS-guided gallbladder drainage in patients with acute cholecystitis with \u2265\u20091 year of follow-up: a systematic review and meta-analysis. Gastrointest Endosc. 2025;S0016510725018450. https:\/\/doi.org\/10.1016\/j.gie.2025.07.025.","DOI":"10.1016\/j.gie.2025.07.025"},{"key":"7087_CR25","doi-asserted-by":"publisher","first-page":"175628482513753","DOI":"10.1177\/17562848251375376","volume":"18","author":"R Pawa","year":"2025","unstructured":"Pawa R, Koutlas N, Cecil A, et al. EUS-guided gallbladder drainage versus percutaneous gallbladder drainage in high-risk patients with acute cholecystitis: a propensity score-matched analysis. Th Adv Gastroenterol. 2025;18:17562848251375376. https:\/\/doi.org\/10.1177\/17562848251375376. Published 2025 Sep 18.","journal-title":"Th Adv Gastroenterol"},{"key":"7087_CR26","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1111\/den.14946","volume":"37","author":"JCY Fok","year":"2025","unstructured":"Fok JCY, Teoh AYB, Chan SM. Endoscopic ultrasound-guided gallbladder drainage for acute cholecystitis. Dig Endosc. 2025;37:93\u2013102. https:\/\/doi.org\/10.1111\/den.14946.","journal-title":"Dig Endosc"},{"key":"7087_CR27","doi-asserted-by":"publisher","first-page":"a","DOI":"10.1055\/a-2521-0084","volume":"13","author":"C Pan","year":"2025","unstructured":"Pan C, Ramai D, Beran A, et al. Endoscopic transpapillary gallbladder stenting vs percutaneous cholecystostomy for managing acute cholecystitis: nationwide propensity score study. Endosc Int Open. 2025;13:a\u20132521. https:\/\/doi.org\/10.1055\/a-2521-0084.","journal-title":"Endosc Int Open"}],"container-title":["BMC Geriatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12877-026-07087-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12877-026-07087-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12877-026-07087-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T10:07:37Z","timestamp":1772186857000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12877-026-07087-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,31]]},"references-count":27,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["7087"],"URL":"https:\/\/doi.org\/10.1186\/s12877-026-07087-5","relation":{},"ISSN":["1471-2318"],"issn-type":[{"value":"1471-2318","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,31]]},"assertion":[{"value":"20 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This retrospective multicenter study was approved by the ethics committees of all participating hospitals (IRB numbers: 2023K047 and LLSC-2025-LW-01). Given the retrospective nature of the study, the requirement for written informed consent was waived.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"275"}}