{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T04:26:04Z","timestamp":1758860764374},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1186\/s12879-015-1276-2","type":"journal-article","created":{"date-parts":[[2015,12,8]],"date-time":"2015-12-08T23:48:58Z","timestamp":1449618538000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Improving the radical cure of vivax malaria (IMPROV): a study protocol for a multicentre randomised, placebo-controlled comparison of short and long course primaquine regimens"],"prefix":"10.1186","volume":"15","author":[{"name":"The IMPROV Study Group","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,12,7]]},"reference":[{"issue":"3","key":"1276_CR1","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.bcmd.2008.12.005","volume":"42","author":"ET Nkhoma","year":"2009","unstructured":"Nkhoma ET, Poole C, Vannappagari V, Hall SA, Beutler E. The global prevalence of glucose-6-phosphate dehydrogenase deficiency: a systematic review and meta-analysis. Blood Cells Mol Dis. 2009;42(3):267\u201378.","journal-title":"Blood Cells Mol Dis"},{"issue":"5","key":"1276_CR2","first-page":"349","volume":"95","author":"PA Reeve","year":"1992","unstructured":"Reeve PA, Toaliu H, Kaneko A, Hall JJ, Ganczakowski M. Acute intravascular haemolysis in Vanuatu following a single dose of primaquine in individuals with glucose-6-phosphate dehydrogenase deficiency. J Trop Med Hyg. 1992;95(5):349\u201351.","journal-title":"J Trop Med Hyg"},{"issue":"9","key":"1276_CR3","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1086\/424663","volume":"39","author":"JK Baird","year":"2004","unstructured":"Baird JK, Hoffman SL. Primaquine therapy for malaria. Clin Infect Dis. 2004;39(9):1336\u201345.","journal-title":"Clin Infect Dis"},{"key":"1276_CR4","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1186\/1475-2875-10-297","volume":"10","author":"NJ White","year":"2011","unstructured":"White NJ. Determinants of relapse periodicity in Plasmodium vivax malaria. Malar J. 2011;10:297.","journal-title":"Malar J"},{"issue":"5","key":"1276_CR5","doi-asserted-by":"crossref","first-page":"736","DOI":"10.4269\/ajtmh.2008.78.736","volume":"78","author":"S Krudsood","year":"2008","unstructured":"Krudsood S, Tangpukdee N, Wilairatana P, Phophak N, Baird JK, Brittenham GM, et al. High-dose primaquine regimens against relapse of Plasmodium vivax malaria. Am J Trop Med Hyg. 2008;78(5):736\u201340.","journal-title":"Am J Trop Med Hyg"},{"key":"1276_CR6","first-page":"621","volume":"22","author":"AS Alving","year":"1960","unstructured":"Alving AS, Johnson CF, Tarlov AR, Brewer GJ, Kellermeyer RW, Carson PE. Mitigation of the haemolytic effect of primaquine and enhancement of its action against exoerythrocytic forms of the Chesson strain of Piasmodium vivax by intermittent regimens of drug administration: a preliminary report. Bull World Health Organ. 1960;22:621\u201331.","journal-title":"Bull World Health Organ"},{"issue":"8","key":"1276_CR7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0002861","volume":"3","author":"T Leslie","year":"2008","unstructured":"Leslie T, Mayan I, Mohammed N, Erasmus P, Kolaczinski J, Whitty CJ, et al. A randomised trial of an eight-week, once weekly primaquine regimen to prevent relapse of Plasmodium vivax in Northwest Frontier Province, Pakistan. PLoS One. 2008;3(8), e2861.","journal-title":"PLoS One"},{"issue":"3","key":"1276_CR8","first-page":"391","volume":"59","author":"DF Clyde","year":"1981","unstructured":"Clyde DF. Clinical problems associated with the use of primaquine as a tissue schizontocidal and gametocytocidal drug. Bull World Health Organ. 1981;59(3):391\u20135.","journal-title":"Bull World Health Organ"},{"issue":"1","key":"1276_CR9","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.pt.2010.08.005","volume":"27","author":"JK Baird","year":"2011","unstructured":"Baird JK, Surjadjaja C. Consideration of ethics in primaquine therapy against malaria transmission. Trends Parasitol. 2011;27(1):11\u20136.","journal-title":"Trends Parasitol"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-015-1276-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T07:48:01Z","timestamp":1567410481000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.biomedcentral.com\/1471-2334\/15\/558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["1276"],"URL":"https:\/\/doi.org\/10.1186\/s12879-015-1276-2","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12]]},"article-number":"558"}}