{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:51:32Z","timestamp":1791816692773,"version":"4.3.4"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"name":"Medical Faculty, Ume\u00e5 University"},{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Norrl\u00e4ndska hj\u00e4rtfonden"},{"DOI":"10.13039\/501100002960","name":"V\u00e4sterbotten L\u00e4ns Landsting","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002960","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009772","name":"Norrbottens l\u00e4ns landsting","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009772","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Anny & Ragnar Wikst\u00e9ns Foundation"},{"name":"County Councils of Northern Sweden (Visare Norr)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1186\/s12879-016-1879-2","type":"journal-article","created":{"date-parts":[[2016,10,13]],"date-time":"2016-10-13T11:35:08Z","timestamp":1476358508000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Human Puumala hantavirus infection in northern Sweden; increased seroprevalence and association to risk and health factors"],"prefix":"10.1186","volume":"16","author":[{"given":"Kristina","family":"Bergstedt Oscarsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alette","family":"Brorstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Baudin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Lindberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika","family":"Forss\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Evander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Eriksson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2018-8592","authenticated-orcid":false,"given":"Clas","family":"Ahlm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,10,13]]},"reference":[{"issue":"2","key":"1879_CR1","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1128\/CMR.00062-09","volume":"23","author":"CB Jonsson","year":"2010","unstructured":"Jonsson CB, Figueiredo LT, Vapalahti O. A global perspective on hantavirus ecology, epidemiology, and disease. Clin Microbiol Rev. 2010;23(2):412\u201341.","journal-title":"Clin Microbiol Rev"},{"issue":"10","key":"1879_CR2","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S1473-3099(03)00774-6","volume":"3","author":"O Vapalahti","year":"2003","unstructured":"Vapalahti O, Mustonen J, Lundkvist A, Henttonen H, Plyusnin A, Vaheri A. Hantavirus infections in Europe. Lancet Infect Dis. 2003;3(10):653\u201361.","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"1879_CR3","doi-asserted-by":"crossref","first-page":"179","DOI":"10.3109\/02813432.2010.506058","volume":"28","author":"A Brorstad","year":"2010","unstructured":"Brorstad A, Bergstedt-Oscarsson K, Ahlm C. Early diagnosis of hantavirus infection by family doctors can reduce inappropriate antibiotic use and hospitalization. Scand J Prim Health Care. 2010;28(3):179\u201384.","journal-title":"Scand J Prim Health Care"},{"issue":"4","key":"1879_CR4","doi-asserted-by":"crossref","first-page":"349","DOI":"10.3109\/00365549709011829","volume":"29","author":"C Ahlm","year":"1997","unstructured":"Ahlm C, Juto P, Stegmayr B, Settergren B, Wadell G, Tarnvik A, Elgh F. Prevalence of serum antibodies to hantaviruses in northern Sweden as measured by recombinant nucleocapsid proteins. Scand J Infect Dis. 1997;29(4):349\u201354.","journal-title":"Scand J Infect Dis"},{"issue":"1","key":"1879_CR5","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1017\/S0950268800051542","volume":"113","author":"C Ahlm","year":"1994","unstructured":"Ahlm C, Linderholm M, Juto P, Stegmayr B, Settergren B. Prevalence of serum IgG antibodies to Puumala virus (haemorrhagic fever with renal syndrome) in northern Sweden. Epidemiol Infect. 1994;113(1):129\u201336.","journal-title":"Epidemiol Infect"},{"issue":"5","key":"1879_CR6","doi-asserted-by":"crossref","first-page":"808","DOI":"10.3201\/eid1405.071124","volume":"14","author":"L Pettersson","year":"2008","unstructured":"Pettersson L, Boman J, Juto P, Evander M, Ahlm C. Outbreak of Puumala virus infection. Sweden Emerg Infect Dis. 2008;14(5):808\u201310.","journal-title":"Sweden Emerg Infect Dis"},{"issue":"10","key":"1879_CR7","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1017\/S0950268810000087","volume":"138","author":"P Makary","year":"2010","unstructured":"Makary P, Kanerva M, Ollgren J, Virtanen MJ, Vapalahti O, Lyytikainen O. Disease burden of Puumala virus infections, 1995\u20132008. Epidemiol Infect. 2010;138(10):1484\u201392.","journal-title":"Epidemiol Infect"},{"issue":"11","key":"1879_CR8","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1086\/516786","volume":"195","author":"M Ferr\u00e9s","year":"2007","unstructured":"Ferr\u00e9s M, Vial P, Marco C, Yanez L, Godoy P, Castillo C, Hjelle B, Delgado I, Lee SJ, Mertz GJ, et al. Prospective evaluation of household contacts of persons with hantavirus cardiopulmonary syndrome in chile. J Infect Dis. 2007;195(11):1563\u201371.","journal-title":"J Infect Dis"},{"issue":"3","key":"1879_CR9","doi-asserted-by":"crossref","first-page":"406","DOI":"10.3201\/eid1403.071242","volume":"14","author":"L Pettersson","year":"2008","unstructured":"Pettersson L, Klingstrom J, Hardestam J, Lundkvist A, Ahlm C, Evander M. Hantavirus RNA in saliva from patients with hemorrhagic fever with renal syndrome. Emerg Infect Dis. 2008;14(3):406\u201311.","journal-title":"Emerg Infect Dis"},{"issue":"2","key":"1879_CR10","doi-asserted-by":"crossref","first-page":"104","DOI":"10.5271\/sjweh.286","volume":"24","author":"C Ahlm","year":"1998","unstructured":"Ahlm C, Thelin A, Elgh F, Juto P, Stiernstrom EL, Holmberg S, Tarnvik A. Prevalence of antibodies specific to Puumala virus among farmers in Sweden. Scand J Work Environ Health. 1998;24(2):104\u20138.","journal-title":"Scand J Work Environ Health"},{"issue":"11","key":"1879_CR11","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.3201\/eid0911.030275","volume":"9","author":"GE Olsson","year":"2003","unstructured":"Olsson GE, Dalerum F, Hornfeldt B, Elgh F, Palo TR, Juto P, Ahlm C. Human hantavirus infections, Sweden. Emerg Infect Dis. 2003;9(11):1395\u2013401.","journal-title":"Emerg Infect Dis"},{"key":"1879_CR12","doi-asserted-by":"crossref","first-page":"27698","DOI":"10.3402\/iee.v5.27698","volume":"5","author":"A Gherasim","year":"2015","unstructured":"Gherasim A, Hjertqvist M, Lundkvist A, Kuhlmann-Berenzon S, Carlson JV, Stenmark S, Widerstrom M, Osterlund A, Boman H, Ahlm C, et al. Risk factors and potential preventive measures for nephropatia epidemica in Sweden 2011\u20132012: a case-control study. Infection Ecol Epidemiol. 2015;5:27698.","journal-title":"Infection Ecol Epidemiol"},{"issue":"4","key":"1879_CR13","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1017\/S095026880999077X","volume":"138","author":"K Vapalahti","year":"2010","unstructured":"Vapalahti K, Virtala AM, Vaheri A, Vapalahti O. Case-control study on Puumala virus infection: smoking is a risk factor. Epidemiol Infect. 2010;138(4):576\u201384.","journal-title":"Epidemiol Infect"},{"key":"1879_CR14","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1186\/1471-2334-13-501","volume":"13","author":"J Rasmuson","year":"2013","unstructured":"Rasmuson J, Lindqvist P, Sorensen K, Hedstrom M, Blomberg A, Ahlm C. Cardiopulmonary involvement in Puumala hantavirus infection. BMC Infect Dis. 2013;13:501.","journal-title":"BMC Infect Dis"},{"issue":"12","key":"1879_CR15","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1161\/CIRCULATIONAHA.113.001870","volume":"129","author":"AM Connolly-Andersen","year":"2014","unstructured":"Connolly-Andersen AM, Hammargren E, Whitaker H, Eliasson M, Holmgren L, Klingstrom J, Ahlm C. Increased risk of acute myocardial infarction and stroke during hemorrhagic fever with renal syndrome: a self-controlled case series study. Circulation. 2014;129(12):1295\u2013302.","journal-title":"Circulation"},{"issue":"6","key":"1879_CR16","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1007\/s10096-010-0918-y","volume":"29","author":"S M\u00e4kel\u00e4","year":"2010","unstructured":"M\u00e4kel\u00e4 S, Jaatinen P, Miettinen M, Salmi J, Ala-Houhala I, Huhtala H, Hurme M, Porsti I, Vaheri A, Mustonen J. Hormonal deficiencies during and after Puumala hantavirus infection. Eur J Clin Microbiol Infect Dis. 2010;29(6):705\u201313.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"11","key":"1879_CR17","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1038\/sj.ki.5000334","volume":"69","author":"MH Miettinen","year":"2006","unstructured":"Miettinen MH, M\u00e4kel\u00e4 SM, Ala-Houhala IO, Huhtala HS, Koobi T, Vaheri AI, Pasternack AI, Porsti IH, Mustonen JT. Ten-year prognosis of Puumala hantavirus-induced acute interstitial nephritis. Kidney Int. 2006;69(11):2043\u20138.","journal-title":"Kidney Int"},{"issue":"4","key":"1879_CR18","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1046\/j.1523-1755.2000.00332.x","volume":"58","author":"S M\u00e4kel\u00e4","year":"2000","unstructured":"M\u00e4kel\u00e4 S, Ala-Houhala I, Mustonen J, Koivisto AM, Kouri T, Turjanmaa V, Vapalahti O, Vaheri A, Pasternack A. Renal function and blood pressure five years after puumala virus-induced nephropathy. Kidney Int. 2000;58(4):1711\u20138.","journal-title":"Kidney Int"},{"issue":"3\u20134","key":"1879_CR19","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/BF01309472","volume":"137","author":"B Niklasson","year":"1994","unstructured":"Niklasson B, Hellsten G, LeDuc J. Hemorrhagic fever with renal syndrome: a study of sequelae following nephropathia epidemica. Arch Virol. 1994;137(3\u20134):241\u20137.","journal-title":"Arch Virol"},{"issue":"3 Suppl 1","key":"1879_CR20","first-page":"S29","volume":"18","author":"S Bothig","year":"1989","unstructured":"Bothig S. WHO MONICA Project: objectives and design. Int J Epidemiol. 1989;18(3 Suppl 1):S29\u201337.","journal-title":"Int J Epidemiol"},{"key":"1879_CR21","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/14034950310001441","volume":"61","author":"B Stegmayr","year":"2003","unstructured":"Stegmayr B, Lundberg V, Asplund K. The events registration and survey procedures in the Northern Sweden MONICA Project. Scand J Public Health Suppl. 2003;61:9\u201317.","journal-title":"Scand J Public Health Suppl"},{"key":"1879_CR22","unstructured":"SCB. Folk- och bostadsr\u00e4kningen 1985; Yrke och socioekonomisk indelning (SEI). Stockholm: Statistiska Centralbyr\u00e5n; 1989."},{"issue":"4","key":"1879_CR23","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1080\/14034940510032301","volume":"33","author":"B Stegmayr","year":"2005","unstructured":"Stegmayr B, Eliasson M, Rodu B. The decline of smoking in northern Sweden. Scand J Public Health. 2005;33(4):321\u20134. discussion 243.","journal-title":"Scand J Public Health"},{"issue":"1","key":"1879_CR24","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.virusres.2008.06.003","volume":"137","author":"M Lindkvist","year":"2008","unstructured":"Lindkvist M, Naslund J, Ahlm C, Bucht G. Cross-reactive and serospecific epitopes of nucleocapsid proteins of three hantaviruses: prospects for new diagnostic tools. Virus Res. 2008;137(1):97\u2013105.","journal-title":"Virus Res"},{"issue":"20","key":"1879_CR25","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1001\/archinte.164.20.2206","volume":"164","author":"L Arcavi","year":"2004","unstructured":"Arcavi L, Benowitz NL. Cigarette smoking and infection. Arch Intern Med. 2004;164(20):2206\u201316.","journal-title":"Arch Intern Med"},{"key":"1879_CR26","unstructured":"LRF. The invisible entrepreneur. Gender and management in the green industry. Stockholm: Lantbrukarnas Riksf\u00f6rbunds J\u00e4mst\u00e4lldhetsakademi; 2009."},{"key":"1879_CR27","unstructured":"Jordbruksverket. Statistikrapport 2011:5; The development of male and female participation in the managing of agricultural holdings in Sweden 1999\u20132010. J\u00f6nk\u00f6ping: Statens Jordbruksverk; 2011."},{"issue":"2","key":"1879_CR28","doi-asserted-by":"crossref","first-page":"c115","DOI":"10.1159\/000213899","volume":"112","author":"MH Miettinen","year":"2009","unstructured":"Miettinen MH, M\u00e4kel\u00e4 SM, Ala-Houhala IO, Huhtala HS, Koobi T, Vaheri AI, Pasternack AI, Porsti IH, Mustonen JT. Tubular proteinuria and glomerular filtration 6\u00a0years after puumala hantavirus-induced acute interstitial nephritis. Nephron Clin Pract. 2009;112(2):c115\u201320.","journal-title":"Nephron Clin Pract"},{"issue":"12","key":"1879_CR29","doi-asserted-by":"crossref","first-page":"3264","DOI":"10.1128\/JCM.35.12.3264-3268.1997","volume":"35","author":"KB Sjolander","year":"1997","unstructured":"Sjolander KB, Elgh F, Kallio-Kokko H, Vapalahti O, Hagglund M, Palmcrantz V, Juto P, Vaheri A, Niklasson B, Lundkvist A. Evaluation of serological methods for diagnosis of Puumala hantavirus infection (nephropathia epidemica). J Clin Microbiol. 1997;35(12):3264\u20138.","journal-title":"J Clin Microbiol"},{"issue":"2","key":"1879_CR30","doi-asserted-by":"crossref","first-page":"c89","DOI":"10.1159\/000314657","volume":"116","author":"MH Miettinen","year":"2010","unstructured":"Miettinen MH, M\u00e4kel\u00e4 SM, Ala-Houhala IO, Huhtala HS, Hurme MA, Koobi T, Partanen JA, Pasternack AI, Vaheri A, Porsti IH, et al. The severity of acute Puumala hantavirus infection does not predict the long-term outcome of patients. Nephron Clin Pract. 2010;116(2):c89\u201394.","journal-title":"Nephron Clin Pract"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-016-1879-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T16:34:33Z","timestamp":1601138073000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-016-1879-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,13]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["1879"],"URL":"https:\/\/doi.org\/10.1186\/s12879-016-1879-2","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,13]]},"article-number":"566"}}