{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T11:53:31Z","timestamp":1782215611349,"version":"3.54.5"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12879-017-2798-6","type":"journal-article","created":{"date-parts":[[2017,10,11]],"date-time":"2017-10-11T08:13:42Z","timestamp":1507709622000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Rational use of Xpert testing in patients with presumptive TB: clinicians should be encouraged to use the test-treat threshold"],"prefix":"10.1186","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1205-1484","authenticated-orcid":false,"given":"Tom","family":"Decroo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aquiles R.","family":"Henr\u00edquez-Trujillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"De Weggheleire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutgarde","family":"Lynen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,10,11]]},"reference":[{"issue":"1","key":"2798_CR1","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1186\/s12879-017-2534-2","volume":"17","author":"SM Hermans","year":"2017","unstructured":"Hermans SM, Babirye JA, Mbabazi O, Kakooza F, Colebunders R, Castelnuovo B, et al. Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert\u2122 MTB\/RIF era: a cohort study. BMC Infect Dis. 2017;17(1):433.","journal-title":"BMC Infect Dis"},{"issue":"7","key":"2798_CR2","doi-asserted-by":"crossref","first-page":"e008155","DOI":"10.1136\/bmjopen-2015-008155","volume":"5","author":"PF Whiting","year":"2015","unstructured":"Whiting PF, Davenport C, Jameson C, Burke M, Sterne JA, Hyde C, et al. How well do health professionals interpret diagnostic information? A systematic review. BMJ Open. 2015;5(7):e008155.","journal-title":"BMJ Open"},{"key":"2798_CR3","first-page":"CD009593","volume":"1","author":"KR Steingart","year":"2014","unstructured":"Steingart KR, Schiller I, Horne DJ, Pai M, Boehme CC, Dendukuri N. Xpert\u00ae MTB\/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database Syst Rev. 2014;1:CD009593.","journal-title":"Cochrane Database Syst Rev"},{"issue":"5","key":"2798_CR4","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1056\/NEJM197507312930505","volume":"293","author":"SG Pauker","year":"1975","unstructured":"Pauker SG, Kassirer JP. Therapeutic decision making: a cost-benefit analysis. N Engl J Med. 1975;293(5):229\u201334.","journal-title":"N Engl J Med"},{"issue":"1","key":"2798_CR5","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1177\/0272989X06297104","volume":"27","author":"P Basinga","year":"2007","unstructured":"Basinga P, Moreira J, Bisoffi Z, Bisig B, Van den Ende J. Why are clinicians reluctant to treat smear-negative tuberculosis? An inquiry about treatment thresholds in Rwanda. Med Decis Mak. 2007;27(1):53\u201360.","journal-title":"Med Decis Mak"},{"issue":"8","key":"2798_CR6","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1136\/jcp.26.8.555","volume":"26","author":"JM Wilson","year":"1973","unstructured":"Wilson JM. Current trends and problems in health screening. J Clin Pathol. 1973;26(8):555\u201363.","journal-title":"J Clin Pathol"},{"key":"2798_CR7","doi-asserted-by":"crossref","DOI":"10.1017\/CBO9781139506779","volume-title":"Decision making in health and medicine: integrating evidence and values","author":"MGM Hunink","year":"2014","unstructured":"Hunink MGM. Decision making in health and medicine: integrating evidence and values. 2nd ed. Cambridge: Cambridge University Press; 2014.","edition":"2"},{"issue":"3","key":"2798_CR8","doi-asserted-by":"crossref","first-page":"249","DOI":"10.5588\/ijtld.16.0801","volume":"21","author":"TH Boyles","year":"2017","unstructured":"Boyles TH. Why do clinical trials of Xpert\u00ae MTB\/RIF fail to show an effect on patient relevant outcomes? Int J Tuberc Lung Dis. 2017;21(3):249\u201350.","journal-title":"Int J Tuberc Lung Dis"},{"issue":"20","key":"2798_CR9","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1056\/NEJM198005153022003","volume":"302","author":"SG Pauker","year":"1980","unstructured":"Pauker SG, Kassirer JP. The threshold approach to clinical decision making. N Engl J Med. 1980;302(20):1109\u201317.","journal-title":"N Engl J Med"},{"issue":"9485","key":"2798_CR10","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/S0140-6736(05)67096-1","volume":"366","author":"J Van den Ende","year":"2005","unstructured":"Van den Ende J, Moreira J, Basinga P, Bisoffi Z. The trouble with likelihood ratios. Lancet. 2005;366(9485):548.","journal-title":"Lancet"},{"issue":"9469","key":"2798_CR11","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1016\/S0140-6736(05)66422-7","volume":"365","author":"DA Grimes","year":"2005","unstructured":"Grimes DA, Schulz KF. Refining clinical diagnosis with likelihood ratios. Lancet. 2005;365(9469):1500\u20135.","journal-title":"Lancet"},{"issue":"8","key":"2798_CR12","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1056\/NEJMoa0907488","volume":"362","author":"KP Cain","year":"2010","unstructured":"Cain KP, McCarthy KD, Heilig CM, Monkongdee P, Tasaneeyapan T, Kanara N, et al. An algorithm for tuberculosis screening and diagnosis in people with HIV. N Engl J Med. 2010;362(8):707\u201316.","journal-title":"N Engl J Med"},{"issue":"3","key":"2798_CR13","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/j.1365-2753.2006.00710.x","volume":"13","author":"J Van den Ende","year":"2007","unstructured":"Van den Ende J, Bisoffi Z, Van Puymbroek H, Van der Stuyft P, Van Gompel A, Derese A, et al. Bridging the gap between clinical practice and diagnostic clinical epidemiology: pilot experiences with a didactic model based on a logarithmic scale. J Eval Clin Pract. 2007;13(3):374\u201380.","journal-title":"J Eval Clin Pract"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-017-2798-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,10,11]],"date-time":"2017-10-11T08:13:46Z","timestamp":1507709626000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-017-2798-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,11]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["2798"],"URL":"https:\/\/doi.org\/10.1186\/s12879-017-2798-6","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,11]]},"article-number":"674"}}