{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T12:04:55Z","timestamp":1768478695785,"version":"3.49.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Cienciativa of CONCYTEC Peru","award":["N\u00b0 193-2015-FONDECYT"],"award-info":[{"award-number":["N\u00b0 193-2015-FONDECYT"]}]},{"name":"Cienciativa of CONCYTEC Peru","award":["N\u00b0 164-2016-FONDECYT"],"award-info":[{"award-number":["N\u00b0 164-2016-FONDECYT"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s12879-018-3541-7","type":"journal-article","created":{"date-parts":[[2018,12,4]],"date-time":"2018-12-04T13:20:07Z","timestamp":1543929607000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Molecular detection and clinical characteristics of Bartonella bacilliformis, Leptospira spp., and Rickettsia spp. in the Southeastern Peruvian Amazon basin"],"prefix":"10.1186","volume":"18","author":[{"given":"Fiorella","family":"Ricapa-Antay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katia","family":"Diaz-Melon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilmer","family":"Silva-Caso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis J.","family":"del Valle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel Angel","family":"Aguilar-Luis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Vasquez-Achaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Palomares-Reyes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Weilg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongmei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Manrique","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juana","family":"del Valle-Mendoza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,12,4]]},"reference":[{"key":"3541_CR1","doi-asserted-by":"publisher","first-page":"472","DOI":"10.4269\/ajtmh.12-0373","volume":"88","author":"OD Lorenzi","year":"2013","unstructured":"Lorenzi OD, Gregory CJ. Santiago LM Acosta H, Galarza IE, Saint Luke\u2019s acute febrile illness investigation tea, et al. acute febrile illness surveillance in a tertiary hospital emergency department: comparison of influenza and dengue virus infections. Am J Trop Med Hyg. 2013;88:472\u201380.","journal-title":"Am J Trop Med Hyg"},{"issue":"2","key":"3541_CR2","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1093\/jpids\/piw016","volume":"5","author":"PY Iroh Tam","year":"2016","unstructured":"Iroh Tam PY, Obaro SK, Storch G. Challenges in the etiology and diagnosis of acute febrile illness in children in low- and middle-income countries. J Pediatric Infect Dis Soc. 2016;5(2):190\u2013205.","journal-title":"J Pediatric Infect Dis Soc."},{"issue":"7","key":"3541_CR3","doi-asserted-by":"publisher","first-page":"e2331","DOI":"10.1371\/journal.pntd.0002331","volume":"7","author":"M Capeding","year":"2013","unstructured":"Capeding M, Chua M, Hadinegoro S, Hussain I, Nallusamy R, Pitisuttithum P, et al. Dengue and other common causes of acute febrile illness in Asia: an active surveillance study in children. PLoS Negl Trop Dis. 2013;7(7):e2331.","journal-title":"PLoS Negl Trop Dis"},{"issue":"8","key":"3541_CR4","doi-asserted-by":"publisher","first-page":"e787","DOI":"10.1371\/journal.pntd.0000787","volume":"4","author":"BM Forshey","year":"2010","unstructured":"Forshey BM, Guevara C, Laguna-Torres VA, Cespedes M, Vargas J, Gianella A, et al. Arboviral etiologies of acute febrile illnesses in Western South America, 2000-2007. PLoS Negl Trop Dis. 2010;4(8):e787.","journal-title":"PLoS Negl Trop Dis"},{"issue":"8","key":"3541_CR5","doi-asserted-by":"publisher","first-page":"e787","DOI":"10.1371\/journal.pntd.0000787","volume":"4","author":"Brett M. Forshey","year":"2010","unstructured":"Forshey BM, Guevara C, Laguna-Torres VA, Cespedes M, Vargas J, Gianella A, Vallejo E, Madrid C, Aguayo N, Gotuzzo E, Suarez V, Morales AM, Beingolea L, Reyes N, Perez J, Negrete M, Rocha C, Morrison AC, Russell KL, Blair PJ, Olson JG, Kochel TJ; NMRCD Febrile Surveillance Working Group. Arboviral etiologies of\u00a0\u00a0acute febrile illnesses in Western South America, 2000-2007. PLoS Negl Trop Dis.\u00a0\u00a02010;4(8):e787.","journal-title":"PLoS Neglected Tropical Diseases"},{"key":"3541_CR6","unstructured":"Red Nacional de Epidemiologia (RENACE). Casos de Dengue por Departamentos Peru 2016. [Internet]. Lima, Per\u00fa. Direcci\u00f3n General de Epidemiolog\u00eda (DGE). [Accessed on 29 Oct 2016; Cited on November 09, 2016] Available at: \n                    http:\/\/www.dge.gob.pe\/portal\/docs\/vigilancia\/sala\/2016\/SE01\/dengue.pdf"},{"key":"3541_CR7","unstructured":"Red Nacional de Epidemiologia (RENACE) Vigilancia del s\u00edndrome febril en \u00e1reas de alto riesgo de transmisi\u00f3n de enfermedades infeccionsas de impacto en salud publica en el Peru. [Internet]. Lima, Per\u00fa. Oficina General de Epidemiolog\u00eda (OGE). [Accessed on 09 Nov 2016; Cited on November 10, 2016] Available at: \n                    http:\/\/www.dge.gob.pe\/publicaciones\/pub_invepi\/iepi05.pdf"},{"issue":"6","key":"3541_CR8","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.3201\/eid1006.030660","volume":"10","author":"M Johnson","year":"2004","unstructured":"Johnson M, Smith H, Joseph P, Gilman R, Bautista C, Campos K, et al. Environmental Exposure and Leptospirosis, Peru. Emerg Infect Dis. 2004;10(6):1016\u201322.","journal-title":"Emerg Infect Dis"},{"issue":"4","key":"3541_CR9","first-page":"180","volume":"20","author":"M Cespedes","year":"2003","unstructured":"Cespedes M, Ormaeche M, Condori P, Balda L, Glenny M. Prevalencia de Leptospirosis y Factores de Riesgo en Personas con Antecedentes de Fiebre en la Provincia de Manu, Madre de Dios, Peru. Rev Peru Med Exp Salud Publica. 2003;20(4):180\u20135.","journal-title":"Rev Peru Med Exp Salud Publica"},{"issue":"7","key":"3541_CR10","doi-asserted-by":"publisher","first-page":"e0004843","DOI":"10.1371\/journal.pntd.0004843","volume":"10","author":"C Kocher","year":"2016","unstructured":"Kocher C, Morrison AC, Leguia M, Loyola S, Castillo R, Galvez H, et al. Rickettsial disease in the Peruvian Amazon Basin. PLoS Negl Trop Dis. 2016;10(7):e0004843.","journal-title":"PLoS Negl Trop Dis"},{"issue":"8","key":"3541_CR11","doi-asserted-by":"publisher","first-page":"1389","DOI":"10.3201\/eid2308.170050","volume":"23","author":"C Kocher","year":"2017","unstructured":"Kocher C, Jiang J, Morrison AC, Castillo R, Leguia M, Loyola S, et al. Serologic evidence of scrub typhus in the Peruvian Amazon. Emerg Infect Dis. 2017;23(8):1389\u201391.","journal-title":"Emerg Infect Dis"},{"issue":"2","key":"3541_CR12","doi-asserted-by":"publisher","first-page":"380","DOI":"10.17843\/rpmesp.2016.332.2098","volume":"33","author":"M Garc\u00eda","year":"2016","unstructured":"Garc\u00eda M, Merino N, Figueroa D, Marcelo A, Tineo V, Manrique C, et al. Detection of Oropouche viral circulation in Madre de Dios region, Peru (December 2015 to January 2016). Rev Peru Med Exp Salud Publica. 2016;33(2):380\u20131.","journal-title":"Rev Peru Med Exp Salud Publica"},{"issue":"5","key":"3541_CR13","doi-asserted-by":"publisher","first-page":"710","DOI":"10.4269\/ajtmh.1998.59.710","volume":"59","author":"KJ Baisley","year":"1998","unstructured":"Baisley KJ, Watts DM, Munstermann LE, Wilson ML. Epidemiology of endemic Oropouche virus transmission in upper Amazonian Peru. Am J Trop Med Hyg. 1998;59(5):710\u20136.","journal-title":"Am J Trop Med Hyg"},{"issue":"2","key":"3541_CR14","first-page":"172","volume":"24","author":"P Aguilar-Le\u00f3n","year":"2016","unstructured":"Aguilar-Le\u00f3n P, Bazalar-Palacios S, Rodriguez-Leyth H. The outbreak of Zika virus in the Americas: actions and challenges in Per\u00f9. Infez Med. 2016;24(2):172\u20133.","journal-title":"Infez Med"},{"issue":"10","key":"3541_CR15","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1016\/j.apjtm.2016.07.030","volume":"9","author":"S Levy-Blitchtein","year":"2016","unstructured":"Levy-Blitchtein S, Del Valle-Mendoza J. Zika virus is arriving at the American continent. Asian Pac J Trop Med. 2016;9(10):1019\u201321.","journal-title":"Asian Pac J Trop Med"},{"key":"3541_CR16","unstructured":"Ministerio de Salud (MINSA). Minsa emite alerta epidemiol\u00f3gica ante circulaci\u00f3n del virus Zika en pa\u00edses de America del Sur. [Internet]. Lima, Per\u00fa. Direcci\u00f3n General de Epidemiolog\u00eda (DGE). [Accessed on 29 Oct 2016; Cited on November 11, 2016] Available at: \n                    http:\/\/www.minsa.gob.pe\/?op=51&nota=17016"},{"key":"3541_CR17","unstructured":"Ministerio de Salud (MINSA). Mapa de Leptospirosis por distritos Per\u00fa 2017. [Internet]. Lima, Per\u00fa. Direcci\u00f3n General de Epidemiolog\u00eda (DGE). [Accessed on 12 Oct 2017; Cited on October 11, 2016] Available at: \n                    http:\/\/www.dge.gob.pe\/portal\/docs\/vigilancia\/sala\/2017\/SE09\/leptospirosis.pdf"},{"issue":"1","key":"3541_CR18","first-page":"99","volume":"24","author":"C Ramal","year":"2007","unstructured":"Ramal C, D\u00edaz E, L\u00f3pez J. Rickettsiosis, enfermedad emergente en Loreto. Evidencia sexol\u00f3gica de 20 casos. Peru. Rev Peru Med Exp Salud Publica. 2007;24(1):99\u2013100.","journal-title":"Rev Peru Med Exp Salud Publica"},{"issue":"3","key":"3541_CR19","doi-asserted-by":"publisher","first-page":"e92283","DOI":"10.1371\/journal.pone.0092283","volume":"9","author":"J Valle-Mendoza Del","year":"2014","unstructured":"Del Valle-Mendoza J, Silva-Caso W, Tinco-Valdez C, Pons M, Del Valle L, Ore V, et al. Diagnosis of Carrion\u2019s disease by direct blood PCR in thin blood smear negative samples. PLoS One. 2014;9(3):e92283.","journal-title":"PLoS One"},{"key":"3541_CR20","unstructured":"Anaya E, Cespedes M, Mostorino R. Bartonellosis en Madre de Dios [Internet]. Lima, Peru. Repositorio del Instituto Nacional de Salud. [Accessed on 12 Oct 2017; Cited on October 16, 2017] Available at: \n                    http:\/\/repositorio.ins.gob.pe\/handle\/INS\/802"},{"issue":"3","key":"3541_CR21","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.jgar.2015.05.004","volume":"3","author":"W Silva-Caso","year":"2015","unstructured":"Silva-Caso W, Pons M, Ruiz J, Del Valle-Mendoza J. Antibiotic resistance in Bartonella bacilliformis clinical isolates from an endemic area of Peru. J Glob Antimicrob Resist. 2015;3(3):222\u20133.","journal-title":"J Glob Antimicrob Resist"},{"issue":"1","key":"3541_CR22","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1186\/s40249-016-0197-7","volume":"5","author":"C Gomes","year":"2016","unstructured":"Gomes C, Pons M, Del Valle-Mendoza J, Ruiz J. Carrion\u2019s disease: an eradicable illness? Infect Dis Poverty. 2016;5(1):105.","journal-title":"Infect Dis Poverty"},{"issue":"3","key":"3541_CR23","doi-asserted-by":"publisher","first-page":"e0004529","DOI":"10.1371\/journal.pntd.0004529","volume":"10","author":"C Gomes","year":"2016","unstructured":"Gomes C, Martinez-Puchol S, Pons M, Bazan J, Tinco C, Del Valle J. Evaluation of PCR approaches for detection of Bartonella bacilliformis in blood samples. PLoS Negl Trop Dis. 2016;10(3):e0004529.","journal-title":"PLoS Negl Trop Dis"},{"issue":"2","key":"3541_CR24","doi-asserted-by":"publisher","first-page":"380","DOI":"10.17843\/rpmesp.2014.312.63","volume":"31","author":"A Huerta","year":"2014","unstructured":"Huerta A, Salas M, Yarinsueca J, Magui\u00f1a C. Carri\u00f3n\u2019s disease complicated with severe acute leptospirosis: a case report. Rev Peru Med Exp Salud Publica. 2014;31(2):380\u20134.","journal-title":"Rev Peru Med Exp Salud Publica"},{"issue":"11","key":"3541_CR25","doi-asserted-by":"publisher","first-page":"e0187897","DOI":"10.1371\/journal.pone.0187897","volume":"12","author":"C Alva-Urcia","year":"2017","unstructured":"Alva-Urcia C, Aguilar-Luis M, Palomares-Reyes C, Silva-Caso W, Suarez-Ognio L, Weilg P, et al. Emerging and reemerging arboviruses: a new threat in eastern Peru. PLoS One. 2017;12(11):e0187897.","journal-title":"PLoS One"},{"issue":"2","key":"3541_CR26","first-page":"427","volume":"42","author":"DM Li","year":"2015","unstructured":"Li DM, Liu YY, Du PC, Song XP, Liu QY. Detection of Bartonella bacilliformis by real-time PCR with TaqMan-MGB probe. Microbiol China. 2015;42(2):427\u201335.","journal-title":"Microbiol China"},{"issue":"1","key":"3541_CR27","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1128\/JCM.01723-12","volume":"51","author":"CY Kato","year":"2013","unstructured":"Kato CY, Chung IH, Robinson LK, Austin AL, Dasch GA, Massung RF. Assessment of real-time PCR assay for detection of rickettsia spp. and rickettsia rickettsii in banked clinical samples. J Clin Microbiol. 2013;51(1):314\u20137.","journal-title":"J Clin Microbiol"},{"key":"3541_CR28","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.diagmicrobio.2009.03.014","volume":"64","author":"RA Stoddard","year":"2009","unstructured":"Stoddard RA, Gee JE, Wilkins PP, McCaustland K, Hoffmaster AR. Detection of pathogenic Leptospira spp. through TaqMan polymerase chain reaction targeting the LipL32 gene. Diagn Microbiol Infect Dis. 2009;64:247\u201355.","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"8","key":"3541_CR29","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1016\/j.cmi.2018.05.001","volume":"24","author":"J Moreira","year":"2018","unstructured":"Moreira J, Bressan CS, Brasil P, Siqueira AM. Epidemiology of acute febrile illness in Latin America. Clin Microbiol Infect. 2018;24(8):827\u201335.","journal-title":"Clin Microbiol Infect"},{"key":"3541_CR30","doi-asserted-by":"publisher","first-page":"e1819","DOI":"10.1371\/journal.pntd.0001819","volume":"6","author":"N Sanchez Clemente","year":"2012","unstructured":"Sanchez Clemente N, Ugarte-Gil CA, Sol\u00f3rzano N, Magui\u00f1a C, Pachas P, et al. Bartonella bacilliformis: a systematic review of the literature to guide the research agenda for elimination. PLoS Negl Trop Dis. 2012;6:e1819.","journal-title":"PLoS Negl Trop Dis"},{"key":"3541_CR31","doi-asserted-by":"publisher","first-page":"344","DOI":"10.4269\/ajtmh.1999.61.344","volume":"61","author":"BA Ellis","year":"1999","unstructured":"Ellis BA, Rotz LD, Leake JAD, Samalvides F, Bernable J. An outbreak of acute Bartonellosis (Oroya fever) in the Urubamba region of Peru, 1998. Am J Trop Med Hyg. 1999;61:344\u20139.","journal-title":"Am J Trop Med Hyg"},{"key":"3541_CR32","volume-title":"Enfermedad de Carri\u00f3n (Bartonelosis) en el Per\u00fa","author":"P Pachas","year":"2001","unstructured":"Pachas P. Enfermedad de Carri\u00f3n (Bartonelosis) en el Per\u00fa. Lima: Ministerio de Salud, OGE, INS; 2001. \n                    http:\/\/bvs.minsa.gob.pe\/local\/ogei\/790_ms-oge110.pdf"},{"key":"3541_CR33","doi-asserted-by":"crossref","unstructured":"Silva-Caso W, Mazulis F, Weilg C, Aguilar-Luis MA, Sandoval I, Correa-Nu\u00f1ez G, Li D, Song X, Liu Q, Del Valle-Mendoza J. Co-infection with Bartonella bacilliformis and Mycobacterium spp. in a coastal region of Peru. BMC Res Notes. 2017;10(1):656.\u00a0","DOI":"10.1186\/s13104-017-2977-y"},{"key":"3541_CR34","unstructured":"Centro Nacional De Epidemiolog\u00cda, Prevenci\u00f3n Y Con. N\u00famero de casos de enfermedad de Carri\u00f3n, Per\u00fa 2013\u20132018* [Internet]. DGE.GOB.PE. 2018 [cited 1 May 2018]. Available from: \n                    http:\/\/www.dge.gob.pe\/portal\/docs\/vigilancia\/sala\/2018\/SE15\/carrion.pdf"},{"key":"3541_CR35","unstructured":"Abela-Ridder B, Berthrat E, Durski K. Global burden of Human Leptospirosis and cross-sectoral interventions for its prevention and control [Internet]. Prince Mahidol Award Conference. 2018 [cited 1 May 2018]. Available from: \n                    http:\/\/www.pmaconference.mahidol.ac.th\/dmdocuments\/2013-PMAC-Poster-P9-Bernadette%20Abela-Ridder.pdf"},{"key":"3541_CR36","unstructured":"N\u00famero de casos de leptospirosis, Per\u00fa 2013\u20132018* [Internet]. DGE.GOB.PE. 2018 [cited 1 May 2018]. Available from: \n                    http:\/\/www.dge.gob.pe\/portal\/docs\/vigilancia\/sala\/2018\/SE15\/leptospirosis.pdf"},{"issue":"6","key":"3541_CR37","doi-asserted-by":"publisher","first-page":"e0003866","DOI":"10.1371\/journal.pntd.0003866","volume":"9","author":"A Taylor","year":"2015","unstructured":"Taylor A, Paris D, Newton PA. Systematic review of the mortality from untreated leptospirosis. PLoS Negl Trop Dis. 2015;9(6):e0003866.","journal-title":"PLoS Negl Trop Dis"},{"key":"3541_CR38","doi-asserted-by":"publisher","first-page":"e1991","DOI":"10.1371\/journal.pntd.0001991","volume":"7","author":"S Tubiana","year":"2013","unstructured":"Tubiana S, Mikulski M, Becam J, et al. Risk factors and predictors of severe leptospirosis in New Caledonia. PLoS Negl Trop Dis. 2013;7:e1991.","journal-title":"PLoS Negl Trop Dis"},{"key":"3541_CR39","doi-asserted-by":"publisher","first-page":"537","DOI":"10.2217\/fmb.14.141","volume":"10","author":"A Luce-Fedrow","year":"2015","unstructured":"Luce-Fedrow A, Mullins K, Kostik AP, St John HK, Jiang J, et al. Strategies for detecting rickettsiae and diagnosing rickettsial diseases. Future Microbiol. 2015;10:537\u201364.","journal-title":"Future Microbiol"},{"issue":"4","key":"3541_CR40","doi-asserted-by":"publisher","first-page":"683","DOI":"10.4269\/ajtmh.2010.09-0355","volume":"82","author":"B Forshey","year":"2010","unstructured":"Forshey B, Stewart A, Morrison A, Galvez H, Rocha C, Astete H, et al. Epidemiology of spotted fever group and typhus group Rickettsial infection in the Amazon Basin of Peru. Am J Trop Med Hyg. 2010;82(4):683\u201390.","journal-title":"Am J Trop Med Hyg"},{"issue":"1","key":"3541_CR41","doi-asserted-by":"publisher","first-page":"76","DOI":"10.17843\/rpmesp.2017.341.2769","volume":"34","author":"R Palacios-Salvatierra","year":"2017","unstructured":"Palacios-Salvatierra R, Anaya-Ram\u00edrez E, Juscamayta-L\u00f3pez J, C\u00e1ceres-Rey O, Mendoza-Uribe L, Mosquera-Visaloth P, Concei\u00e7\u00e3o-Silva F. Perfil epidemiol\u00f3gico y molecular de Rickettsiosis en localidades de frontera peruana. Revista Peruana De Medicina Experimental Y Salud P\u00faBlica. 2017;34(1):76\u201384.","journal-title":"Revista Peruana De Medicina Experimental Y Salud P\u00faBlica"},{"issue":"1","key":"3541_CR42","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1186\/s12879-017-2239-6","volume":"17","author":"L Faruque","year":"2017","unstructured":"Faruque L, Zaman R, Gurley E, Massung R, Alamgir A, Galloway R, et al. Prevalence and clinical presentation of rickettsia, Coxiella, Leptospira, Bartonella and chikungunya virus infections among hospital-based febrile patients from December 2008 to November 2009 in Bangladesh. BMC Infect Dis. 2017;17(1):141.","journal-title":"BMC Infect Dis"},{"issue":"5","key":"3541_CR43","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1097\/QCO.0b013e328363811b","volume":"26","author":"L Blanton","year":"2013","unstructured":"Blanton L. Rickettsial infections in the tropics and in the traveler. Curr Opin Infect Dis. 2013;26(5):435\u201340.","journal-title":"Curr Opin Infect Dis"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-018-3541-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12879-018-3541-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-018-3541-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T00:08:29Z","timestamp":1575418109000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-018-3541-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["3541"],"URL":"https:\/\/doi.org\/10.1186\/s12879-018-3541-7","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"11 May 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 November 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 December 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study has been approved by two independent Ethics Committees from <i>Universidad Peruana de Ciencias Aplicadas<\/i> and <i>Hospital Regional de Cajamarca.<\/i> A written informed consent was signed before enrollment; for participants under 18\u2009years old the informed consent was signed by their respective guardians before enrollment.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not Applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"On behalf of all authors, the corresponding author states that there are no conflicts of interest or funding related to this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"618"}}