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The pretest studies were approved by the responsible ethics committee of the German Federal States of each of the 18 study centers (such as for Augsburg: Ethics Committee of the State Board of Physicians of the German federal state of Bavaria; Bremen: Ethics Committee of the University of Bremen; Essen: Ethics Committee of the University Clinics of Essen; Hannover: Ethics Committee of the State Board of Physicians of the German federal state of Lower Saxony; Hamburg: Ethics Committee of the State Board of Physicians of the federal state of Hamburg; and Heidelberg: Ethics Committee of the Medical Faculty of Heidelberg). 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