{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T20:59:09Z","timestamp":1769201949011,"version":"3.49.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T00:00:00Z","timestamp":1564099200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T00:00:00Z","timestamp":1564099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12879-019-4219-5","type":"journal-article","created":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T09:02:44Z","timestamp":1564131764000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Clinical and microbiological characteristics and outcomes of community-acquired sepsis among adults: a single center, 1-year retrospective observational cohort study from Hungary"],"prefix":"10.1186","volume":"19","author":[{"given":"Balint Gergely","family":"Szabo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebeka","family":"Kiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin Szidonia","family":"Lenart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bence","family":"Marosi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eszter","family":"Vad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Botond","family":"Lakatos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9459-7316","authenticated-orcid":false,"given":"Eszter","family":"Ostorhazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,7,26]]},"reference":[{"issue":"4","key":"4219_CR1","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1007\/s00134-003-1662-x","volume":"29","author":"MM Levy","year":"2003","unstructured":"Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, et al. 2001 SCCM\/ESICM\/ACCP\/ATS\/SIS international Sepsis definitions conference. Intensive Care Med. 2003;29(4):530\u20138.","journal-title":"Intensive Care Med"},{"issue":"6","key":"4219_CR2","doi-asserted-by":"publisher","first-page":"1644","DOI":"10.1378\/chest.101.6.1644","volume":"101","author":"RC Bone","year":"1992","unstructured":"Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. Definitions for Sepsis and organ failure and guidelines for the use of innovative therapies in Sepsis. Chest. 1992;101(6):1644\u201355.","journal-title":"Chest"},{"issue":"8","key":"4219_CR3","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1001\/jama.2016.0287","volume":"315","author":"M Singer","year":"2016","unstructured":"Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for Sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801\u201310.","journal-title":"JAMA"},{"issue":"16","key":"4219_CR4","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1056\/NEJMoa022139","volume":"348","author":"GM Martin","year":"2003","unstructured":"Martin GM, Mannino DM, Eaton S, Moss M. The epidemiology of Sepsis in the United States from 1979 through 2000. N Engl J Med. 2003;348(16):1546\u201354.","journal-title":"N Engl J Med"},{"issue":"1","key":"4219_CR5","doi-asserted-by":"publisher","first-page":"4","DOI":"10.4161\/viru.27372","volume":"5","author":"FB Mayr","year":"2014","unstructured":"Mayr FB, Yende S, Angus DC. Epidemiology of severe sepsis. Virulence. 2014;5(1):4\u201311.","journal-title":"Virulence"},{"issue":"13","key":"4219_CR6","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.1001\/jama.2014.2637","volume":"311","author":"KM Kaukonen","year":"2014","unstructured":"Kaukonen KM, Bailey M, Suzuki S, Pilcher D, Bellomo R. Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000-2012. JAMA. 2014;311(13):1308\u201316.","journal-title":"JAMA"},{"key":"4219_CR7","volume-title":"CDC vital signs. Centers for Disease Control and Prevention","author":"Making Health Care Safer","year":"2016","unstructured":"Making Health Care Safer. Think sepsis. Time matters. In: CDC vital signs. Centers for Disease Control and Prevention; 2016. \n                              \n                                 https:\/\/www.cdc.gov\/vitalsigns\/pdf\/2016-08-vitalsigns.pdf\n                              \n                              \n                           . Accessed 10 Dec 2018."},{"key":"4219_CR8","unstructured":"Improving the prevention, diagnosis and clinical management of sepsis. In: Report by the secretariat. World Health Organization (Executive Board, 140.). 2017. \n                              \n                                 http:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/273181\/B140_12-en.pdf\n                              \n                              \n                           . Accessed 10 Dec 2018."},{"issue":"3","key":"4219_CR9","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1007\/s15010-008-8203-z","volume":"37","author":"R Beale","year":"2009","unstructured":"Beale R, Reinhart K, Brunkhorst FM, Dobb G, Levy M, Martin G, et al. Promoting global research excellence in severe Sepsis (PROGRESS): lessons from an international sepsis registry. Infection. 2009;37(3):222\u201332.","journal-title":"Infection"},{"issue":"2","key":"4219_CR10","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1007\/s00134-001-1143-z","volume":"28","author":"C Alberti","year":"2002","unstructured":"Alberti C, Brun-Buisson C, Burchardi H, Martin C, Goodman S, Artigas A, et al. Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study. Intensive Care Med. 2002;28(2):108\u201321.","journal-title":"Intensive Care Med"},{"issue":"2","key":"4219_CR11","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1111\/aas.12848","volume":"61","author":"S Nyg\u00e5rd","year":"2017","unstructured":"Nyg\u00e5rd S, Skrede S, Langeland N, Flaatten H. An observational study of community-acquired severe sepsis comparing intensive care and non-intensive care patients. Acta Anaesthesiol Scand. 2017;61(2):194\u2013204.","journal-title":"Acta Anaesthesiol Scand"},{"issue":"4","key":"4219_CR12","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.medcli.2016.04.015","volume":"147","author":"J Almirall","year":"2016","unstructured":"Almirall J, Guell E, Capdevila JA, Campins L, Palomera E, Martinez R, et al. Epidemiology of community-acquired severe sepsis. A population-based study. Med Clin (Barc). 2016;147(4):139\u201343.","journal-title":"Med Clin (Barc)"},{"issue":"3","key":"4219_CR13","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","volume":"18","author":"AP Magiorakos","year":"2012","unstructured":"Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18(3):268\u201381.","journal-title":"Clin Microbiol Infect"},{"issue":"5","key":"4219_CR14","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","volume":"40","author":"ME Charlson","year":"1987","unstructured":"Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying comorbidity development in longitudinal prognostic studies: development and validation. J Chron Dis. 1987;40(5):373\u201383.","journal-title":"J Chron Dis"},{"key":"4219_CR15","unstructured":"Bojer AK, Kov\u00e1cs M, Simor \u00c9, V\u00f6r\u00f6s Cs, Waffenschmidt J. 3. Orsz\u00e1gos adatok: 2011. \u00e9vi n\u00e9psz\u00e1ml\u00e1l\u00e1s. K\u00f6zponti Statisztikai Hivatal. 2013. \n                              https:\/\/www.ksh.hu\/docs\/hun\/xftp\/idoszaki\/nepsz2011\/nepsz_orsz_2011.pdf\n                              \n                           . Accessed 10 Dec 2018."},{"issue":"121","key":"4219_CR16","first-page":"1","volume":"14","author":"ST Nyg\u00e5rd","year":"2014","unstructured":"Nyg\u00e5rd ST, Langeland N, Flaatten HK, Fanebust R, Haugen O, Skrede S. Aetiology, antimicrobial therapy and outcome of patients with community acquired severe sepsis: a prospective study in a Norwegian university hospital. BMC Infect Dis. 2014;14(121):1\u201311.","journal-title":"BMC Infect Dis"},{"issue":"1","key":"4219_CR17","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1097\/CCM.0000000000000611","volume":"43","author":"DP Henriksen","year":"2015","unstructured":"Henriksen DP, Laursen CB, Jensen TG, Hallas J, Pedersen C, Lassen AT. Incidence rate of community-acquired sepsis among hospitalized acute medical patients-a population-based survey. Crit Care Med. 2015;43(1):13\u201321.","journal-title":"Crit Care Med"},{"issue":"7","key":"4219_CR18","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1097\/CCM.0000000000001666","volume":"44","author":"HE Wang","year":"2016","unstructured":"Wang HE, Donnelly JP, Griffin R, Levitan EB, Shapiro NI, Howard G, et al. Derivation of novel risk prediction scores for community-acquired Sepsis and severe Sepsis. Crit Care Med. 2016;44(7):1285\u201394.","journal-title":"Crit Care Med"},{"issue":"1","key":"4219_CR19","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2013-004283","volume":"4","author":"HE Wang","year":"2014","unstructured":"Wang HE, Szychowski JM, Griffin R, Safford MM, Shapiro NI, Howard G. Long-term mortality after community-acquired sepsis: a longitudinal population-based cohort study. BMJ Open. 2014;4(1):e004283.","journal-title":"BMJ Open"},{"issue":"4","key":"4219_CR20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0124838","volume":"10","author":"DP Henriksen","year":"2015","unstructured":"Henriksen DP, Pottegard A, Laursen CB, Jensen TG, Hallas J, Pedersen C, et al. Risk factors for hospitalization due to community-acquired sepsis - a population-based case-control study. PLoS One. 2015;10(4):e0124838.","journal-title":"PLoS One"},{"key":"4219_CR21","volume":"2012","author":"K Grozdanovski","year":"2012","unstructured":"Grozdanovski K, Milenkovic Z, Demiri I, Spasovska K. Prediction of outcome from community-acquired severe sepsis and septic shock in tertiary-care university hospital in a developing country. Crit Care Res Pract. 2012;2012:182324.","journal-title":"Crit Care Res Pract"},{"issue":"6","key":"4219_CR22","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1097\/MEJ.0000000000000379","volume":"24","author":"DP Henriksen","year":"2017","unstructured":"Henriksen DP, Pottegard A, Laursen CB, Jensen TG, Hallas J, Pedersen C, et al. Intermediate-term and long-term mortality among acute medical patients hospitalized with community-acquired sepsis: a population-based study. Eur J Emerg Med. 2017;24(6):404\u201310.","journal-title":"Eur J Emerg Med"},{"issue":"4","key":"4219_CR23","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/j.diagmicrobio.2013.08.009","volume":"77","author":"L De Bus","year":"2013","unstructured":"De Bus L, Coessens G, Boelens J, Claeys G, Decruyenaere J, Depuydt P. Microbial etiology and antimicrobial resistance in healthcare-associated versus community-acquired and hospital-acquired bloodstream infection in a tertiary care hospital. Diagn Microbiol Infect Dis. 2013;77(4):341\u20135.","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"5","key":"4219_CR24","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1016\/j.jiph.2014.12.003","volume":"8","author":"S Baharoon","year":"2015","unstructured":"Baharoon S, Telmesani A, Tamim H, Alsafi E, Aljohani S, Mahmoud E, et al. Community- versus nosocomial-acquired severe sepsis and septic shock in patients admitted to a tertiary intensive care in Saudi Arabia, etiology and outcome. J Infect Public Health. 2015;8(5):418\u201324.","journal-title":"J Infect Public Health"},{"issue":"3","key":"4219_CR25","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1111\/j.1469-0691.2012.03776.x","volume":"19","author":"J Goncalves-Pereira","year":"2013","unstructured":"Goncalves-Pereira J, Povoa PR, Lobo C, Carneiro AH. Bloodstream infections as a marker of community-acquired sepsis severity. Results from the Portuguese community-acquired sepsis study (SACiUCI study). Clin Microbiol Infect. 2013;19(3):242\u20138.","journal-title":"Clin Microbiol Infect"},{"issue":"11","key":"4219_CR26","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.3346\/jkms.2012.27.11.1308","volume":"27","author":"DW Park","year":"2012","unstructured":"Park DW, Chun BC, Kim JM, Sohn JW, Peck KR, Kim YS, et al. Epidemiological and clinical characteristics of community-acquired severe sepsis and septic shock: a prospective observational study in 12 university hospitals in Korea. J Korean Med Sci. 2012;27(11):1308\u201314.","journal-title":"J Korean Med Sci"},{"issue":"8","key":"4219_CR27","doi-asserted-by":"publisher","first-page":"e781","DOI":"10.1016\/j.cmi.2015.05.018","volume":"21","author":"M Sogaard","year":"2015","unstructured":"Sogaard M, Thomsen RW, Bang RB, Schonheyder HC, Norgaard M. Trends in length of stay, mortality and readmission among patients with community-acquired bacteraemia. Clin Microbiol Infect. 2015;21(8):e781\u20137.","journal-title":"Clin Microbiol Infect"},{"key":"4219_CR28","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1186\/1471-2334-13-344","volume":"13","author":"P Retamar","year":"2013","unstructured":"Retamar P, Lopez-Prieto MD, Natera C, de Cueto M, Nuno E, Herrero M, Fernandez-Sanchez F, Munoz A, Tellez F, Becerril B, et al. Reappraisal of the outcome of healthcare-associated and community-acquired bacteramia: a prospective cohort study. BMC Infect Dis. 2013;13:344.","journal-title":"BMC Infect Dis"},{"issue":"126","key":"4219_CR29","first-page":"1","volume":"14","author":"JC Lim","year":"2014","unstructured":"Lim JC, Cheng AC, Kong DC, Peleg AY. Community-onset bloodstream infection with multidrug-resistant organisms: a matched case-control study. BMC Infect Dis. 2014;14(126):1\u20139.","journal-title":"BMC Infect Dis"},{"issue":"3","key":"4219_CR30","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.jiph.2014.01.001","volume":"7","author":"CM Wolfe","year":"2014","unstructured":"Wolfe CM, Cohen B, Larson E. Prevalence and risk factors for antibiotic-resistant community-associated bloodstream infections. J Infect Public Health. 2014;7(3):224\u201332.","journal-title":"J Infect Public Health"},{"issue":"1","key":"4219_CR31","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.ijantimicag.2016.09.032","volume":"49","author":"JR Zahar","year":"2017","unstructured":"Zahar JR, Lesprit P, Ruckly S, Eden A, Hikombo H, Bernard L, et al. Predominance of healthcare-associated cases among episodes of community-onset bacteraemia due to extended-spectrum beta-lactamase-producing Enterobacteriaceae. Int J Antimicrob Agents. 2017;49(1):67\u201373.","journal-title":"Int J Antimicrob Agents"},{"issue":"11","key":"4219_CR32","doi-asserted-by":"publisher","first-page":"2509","DOI":"10.1097\/01.CCM.0000287587.43801.9C","volume":"35","author":"SI Blot","year":"2007","unstructured":"Blot SI, Rodriguez A, Sole-Violan J, Blanquer J, Almirall J, Rello J, et al. Effects of delayed oxygenation assessment on time to antibiotic delivery and mortality in patients with severe community-acquired pneumonia. Crit Care Med. 2007;35(11):2509\u201314.","journal-title":"Crit Care Med"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-019-4219-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12879-019-4219-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-019-4219-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T23:06:27Z","timestamp":1595631987000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-019-4219-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,26]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["4219"],"URL":"https:\/\/doi.org\/10.1186\/s12879-019-4219-5","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,26]]},"assertion":[{"value":"8 February 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study protocol was in accordance with the Helsinki Declaration and international ethical standards. The study protocol has been approved and administrative permission to access raw data was granted by the Institutional Ethical Board of South Pest Central Hospital, National Institute of Hematology and Infectious Diseases (Issue No. IKEB\/37\/2016). Obtaining informed consent is not required for this type of study.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"584"}}