{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:05:51Z","timestamp":1792188351526,"version":"4.4.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T00:00:00Z","timestamp":1566950400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T00:00:00Z","timestamp":1566950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12879-019-4394-4","type":"journal-article","created":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T10:05:25Z","timestamp":1566986725000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Risk factors for mortality in patients with Stenotrophomonas maltophilia bacteremia and clinical impact of quinolone\u2013resistant strains"],"prefix":"10.1186","volume":"19","author":[{"given":"Eun Jin","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Chan","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Young","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4025-4542","authenticated-orcid":false,"given":"Su Jin","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nam Su","family":"Ku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Yong","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joon-Sup","family":"Yeom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Goo","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,8,28]]},"reference":[{"issue":"1","key":"4394_CR1","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1128\/CMR.11.1.57","volume":"11","author":"M Denton","year":"1998","unstructured":"Denton M, Kerr KG. Microbiological and clinical aspects of infection associated with Stenotrophomonas maltophilia. Clin Microbiol Rev. 1998;11(1):57\u201380.","journal-title":"Clin Microbiol Rev"},{"issue":"1","key":"4394_CR2","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1111\/j.1365-2672.2005.02573.x","volume":"99","author":"D Hoefel","year":"2005","unstructured":"Hoefel D, Monis PT, Grooby WL, Andrews S, Saint CP. Profiling bacterial survival through a water treatment process and subsequent distribution system. J Appl Microbiol. 2005;99(1):175\u201386.","journal-title":"J Appl Microbiol"},{"issue":"9","key":"4394_CR3","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.2217\/fmb.09.84","volume":"4","author":"ME Falagas","year":"2009","unstructured":"Falagas ME, Kastoris AC, Vouloumanou EK, Rafailidis PI, Kapaskelis AM, Dimopoulos G. Attributable mortality of Stenotrophomonas maltophilia infections: a systematic review of the literature. Future Microbiol. 2009;4(9):1103\u20139.","journal-title":"Future Microbiol"},{"issue":"3","key":"4394_CR4","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1086\/314043","volume":"31","author":"A Micozzi","year":"2000","unstructured":"Micozzi A, Venditti M, Monaco M, Friedrich A, Taglietti F, Santilli S, et al. Bacteremia due to Stenotrophomonas maltophilia in patients with hematologic malignancies. Clin Infect Dis. 2000;31(3):705\u201311.","journal-title":"Clin Infect Dis"},{"issue":"1","key":"4394_CR5","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1086\/313591","volume":"30","author":"JA Labarca","year":"2000","unstructured":"Labarca JA, Leber AL, Kern VL, Territo MC, Brankovic LE, Bruckner DA, et al. Outbreak of Stenotrophomonas maltophilia bacteremia in allogenic bone marrow transplant patients: role of severe neutropenia and mucositis. Clin Infect Dis. 2000;30(1):195\u20137.","journal-title":"Clin Infect Dis"},{"issue":"Suppl 2","key":"4394_CR6","doi-asserted-by":"publisher","first-page":"S104","DOI":"10.1086\/320183","volume":"32","author":"AC Gales","year":"2001","unstructured":"Gales AC, Jones RN, Forward KR, Linares J, Sader HS, Verhoef J. Emerging importance of multidrug-resistant Acinetobacter species and Stenotrophomonas maltophilia as pathogens in seriously ill patients: geographic patterns, epidemiological features, and trends in the SENTRY antimicrobial surveillance program (1997-1999). Clin Infect Dis. 2001;32(Suppl 2):S104\u201313.","journal-title":"Clin Infect Dis"},{"issue":"2","key":"4394_CR7","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1128\/AAC.44.2.287-293.2000","volume":"44","author":"L Zhang","year":"2000","unstructured":"Zhang L, Li XZ, Poole K. Multiple antibiotic resistance in Stenotrophomonas maltophilia: involvement of a multidrug efflux system. Antimicrob Agents Chemother. 2000;44(2):287\u201393.","journal-title":"Antimicrob Agents Chemother"},{"issue":"5","key":"4394_CR8","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1128\/AAC.41.5.1140","volume":"41","author":"A Alonso","year":"1997","unstructured":"Alonso A, Martinez JL. Multiple antibiotic resistance in Stenotrophomonas maltophilia. Antimicrob Agents Chemother. 1997;41(5):1140\u20132.","journal-title":"Antimicrob Agents Chemother"},{"issue":"5","key":"4394_CR9","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/S1473-3099(09)70083-0","volume":"9","author":"WJ Looney","year":"2009","unstructured":"Looney WJ, Narita M, Muhlemann K. Stenotrophomonas maltophilia: an emerging opportunist human pathogen. Lancet Infect Dis. 2009;9(5):312\u201323.","journal-title":"Lancet Infect Dis"},{"key":"4394_CR10","doi-asserted-by":"publisher","first-page":"658","DOI":"10.3389\/fmicb.2015.00658","volume":"6","author":"MB Sanchez","year":"2015","unstructured":"Sanchez MB. Antibiotic resistance in the opportunistic pathogen Stenotrophomonas maltophilia. Front Microbiol. 2015;6:658.","journal-title":"Front Microbiol"},{"issue":"4","key":"4394_CR11","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1007\/s10096-007-0279-3","volume":"26","author":"AC Nicodemo","year":"2007","unstructured":"Nicodemo AC, Paez JI. Antimicrobial therapy for Stenotrophomonas maltophilia infections. Eur J Clin Microbiol Infect Dis. 2007;26(4):229\u201337.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"1","key":"4394_CR12","doi-asserted-by":"publisher","first-page":"62","DOI":"10.3346\/jkms.2013.28.1.62","volume":"28","author":"HS Chung","year":"2013","unstructured":"Chung HS, Hong SG, Kim YR, Shin KS, Whang DH, Ahn JY, et al. Antimicrobial susceptibility of stenotrophomonas maltophilia isolates from Korea, and the activity of antimicrobial combinations against the isolates. J Korean Med Sci. 2013;28(1):62\u20136.","journal-title":"J Korean Med Sci"},{"issue":"1","key":"4394_CR13","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1128\/AAC.01682-13","volume":"58","author":"SY Cho","year":"2014","unstructured":"Cho SY, Kang CI, Kim J, Ha YE, Chung DR, Lee NY, et al. Can levofloxacin be a useful alternative to trimethoprim-sulfamethoxazole for treating Stenotrophomonas maltophilia bacteremia? Antimicrob Agents Chemother. 2014;58(1):581\u20133.","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"4394_CR14","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1093\/jac\/45.1.115","volume":"45","author":"G Bonfiglio","year":"2000","unstructured":"Bonfiglio G, Cascone C, Azzarelli C, Cafiso V, Marchetti F, Stefani S. Levofloxacin in vitro activity and time-kill evaluation of Stenotrophomonas maltophilia clinical isolates. J Antimicrob Chemother. 2000;45(1):115\u20137.","journal-title":"J Antimicrob Chemother"},{"issue":"1","key":"4394_CR15","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1128\/AAC.01324-13","volume":"58","author":"YL Wang","year":"2014","unstructured":"Wang YL, Scipione MR, Dubrovskaya Y, Papadopoulos J. Monotherapy with fluoroquinolone or trimethoprim-sulfamethoxazole for treatment of Stenotrophomonas maltophilia infections. Antimicrob Agents Chemother. 2014;58(1):176\u201382.","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"4394_CR16","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.jmii.2012.08.014","volume":"47","author":"YT Chang","year":"2014","unstructured":"Chang YT, Lin CY, Lu PL, Lai CC, Chen TC, Chen CY, et al. Stenotrophomonas maltophilia bloodstream infection: comparison between community-onset and hospital-acquired infections. Wei mian yu gan ran za zhi. 2014;47(1):28\u201335.","journal-title":"Wei mian yu gan ran za zhi"},{"issue":"3","key":"4394_CR17","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.jmii.2013.09.005","volume":"48","author":"CJ Pien","year":"2015","unstructured":"Pien CJ, Kuo HY, Chang SW, Chen PR, Yeh HW, Liu CC, et al. Risk factors for levofloxacin resistance in Stenotrophomonas maltophilia from respiratory tract in a regional hospital. Wei mian yu gan ran za zhi. 2015;48(3):291\u20135.","journal-title":"Wei mian yu gan ran za zhi"},{"issue":"2","key":"4394_CR18","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.jmii.2011.09.028","volume":"45","author":"H Wu","year":"2012","unstructured":"Wu H, Wang JT, Shiau YR, Wang HY, Lauderdale TL, Chang SC. A multicenter surveillance of antimicrobial resistance on Stenotrophomonas maltophilia in Taiwan. Wei mian yu gan ran za zhi. 2012;45(2):120\u20136.","journal-title":"Wei mian yu gan ran za zhi"},{"issue":"5","key":"4394_CR19","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.ajic.2008.03.002","volume":"36","author":"TC Horan","year":"2008","unstructured":"Horan TC, Andrus M, Dudeck MA. CDC\/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control. 2008;36(5):309\u201332.","journal-title":"Am J Infect Control"},{"issue":"3","key":"4394_CR20","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1086\/519283","volume":"45","author":"JC McGregor","year":"2007","unstructured":"McGregor JC, Rich SE, Harris AD, Perencevich EN, Osih R, Lodise TP Jr, et al. A systematic review of the methods used to assess the association between appropriate antibiotic therapy and mortality in bacteremic patients. Clin Infect Dis. 2007;45(3):329\u201337.","journal-title":"Clin Infect Dis"},{"issue":"5","key":"4394_CR21","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","volume":"40","author":"ME Charlson","year":"1987","unstructured":"Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373\u201383.","journal-title":"J Chronic Dis"},{"key":"4394_CR22","volume-title":"Clinical and laboratory standards institute. Performance standards for antimicrobial susceptibility testing; 25th informational supplement","author":"JB Patel","year":"2015","unstructured":"Patel JB, Cockerill FR III, Bradford PA, Eliopoulos GM, Hindler JA, Jenkins SG, et al. Clinical and laboratory standards institute. Performance standards for antimicrobial susceptibility testing; 25th informational supplementvol. 35 Number 3: CLSI; 2015: (Document M100-S124) CLSI; 2015."},{"issue":"2","key":"4394_CR23","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.jhin.2008.05.020","volume":"70","author":"JI Paez","year":"2008","unstructured":"Paez JI, Costa SF. Risk factors associated with mortality of infections caused by Stenotrophomonas maltophilia: a systematic review. J Hosp Infect. 2008;70(2):101\u20138.","journal-title":"J Hosp Infect"},{"issue":"4","key":"4394_CR24","doi-asserted-by":"publisher","first-page":"987","DOI":"10.3349\/ymj.2014.55.4.987","volume":"55","author":"JH Baek","year":"2014","unstructured":"Baek JH, Kim CO, Jeong SJ, Ku NS, Han SH, Choi JY, et al. Clinical factors associated with acquisition of resistance to levofloxacin in Stenotrophomonas maltophilia. Yonsei Med J. 2014;55(4):987\u201393.","journal-title":"Yonsei Med J"},{"issue":"1","key":"4394_CR25","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.ajic.2017.07.003","volume":"46","author":"Hsuan-Yin Ma","year":"2018","unstructured":"Ma HY, Hung IC, Huang YH, Chang YY, Sheng WH, Wang JT, et al. Prognostic factors of health care-associated bloodstream infection in adult patients >\/=40 years of age. Am J Infect Control. 2018;46(1):111\u20134.","journal-title":"American Journal of Infection Control"},{"issue":"5","key":"4394_CR26","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1007\/s10096-010-0882-6","volume":"29","author":"H Araoka","year":"2010","unstructured":"Araoka H, Baba M, Yoneyama A. Risk factors for mortality among patients with Stenotrophomonas maltophilia bacteremia in Tokyo, Japan, 1996-2009. Eur J Clin Microbiol Infect Dis. 2010;29(5):605\u20138.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"1","key":"4394_CR27","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1053\/jinf.2002.0978","volume":"45","author":"ND Friedman","year":"2002","unstructured":"Friedman ND, Korman TM, Fairley CK, Franklin JC, Spelman DW. Bacteraemia due to Stenotrophomonas maltophilia: an analysis of 45 episodes. J Infect. 2002;45(1):47\u201353.","journal-title":"J Infect"},{"issue":"31","key":"4394_CR28","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000004375","volume":"95","author":"YD Jeon","year":"2016","unstructured":"Jeon YD, Jeong WY, Kim MH, Jung IY, Ahn MY, Ann HW, et al. Risk factors for mortality in patients with Stenotrophomonas maltophilia bacteremia. Medicine. 2016;95(31):e4375.","journal-title":"Medicine"},{"issue":"2","key":"4394_CR29","doi-asserted-by":"publisher","first-page":"137","DOI":"10.2169\/internalmedicine.56.6141","volume":"56","author":"H Ebara","year":"2017","unstructured":"Ebara H, Hagiya H, Haruki Y, Kondo E, Otsuka F. Clinical characteristics of Stenotrophomonas maltophilia bacteremia: a regional report and a review of a Japanese case series. Internal Med. 2017;56(2):137\u201342.","journal-title":"Internal Med"},{"issue":"1","key":"4394_CR30","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1179\/joc.1999.11.1.28","volume":"11","author":"SC Sanyal","year":"1999","unstructured":"Sanyal SC, Mokaddas EM. The increase in carbapenem use and emergence of Stenotrophomonas maltophilia as an important nosocomial pathogen. J Chemother. 1999;11(1):28\u201333.","journal-title":"J Chemother"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-019-4394-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12879-019-4394-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-019-4394-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T19:08:48Z","timestamp":1598468928000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-019-4394-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,28]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["4394"],"URL":"https:\/\/doi.org\/10.1186\/s12879-019-4394-4","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,28]]},"assertion":[{"value":"26 March 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was approved by the institutional review board of the Yonsei University Health System Clinical Trial Center. The informed consent was waived because this study was a retrospective study with review of related data through the electronic medical record. The datasets used and\/or analyzed during the current study available from the corresponding author on reasonable request.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"754"}}