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Providing updated serologic data can improve both surveillance and disease control programs. This study is aimed to determine the seroprevalence of markers for viral hepatitis (A, B, C, D and E) and the epidemiology of such infections in the general population of southern Iran\u2019s Hormozgan province.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Between 2016 and 2017, a total of 562 individuals with ages ranging from 1 to 86\u2009years, who visited governmental public laboratories for routine check-ups, were tested for the presence of serological markers to hepatitis virus types A to E using enzyme-linked immunosorbent assays.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The overall anti-hepatitis A virus (HAV) antibody seroprevalence was 93.2% (524\/562). The prevalence of anti-hepatitis E virus (HEV) antibodies was 15.8% (89\/562) among which 1.6% (9\/562) of the seropositive individuals also had evidence of recent exposure to the virus (IgM positivity). Two and a half percent (14\/562) were positive for hepatitis B surface (HBs) antigen, whereas 11.6% (65\/562) tested positive for anti-hepatitis B core (HBc) antibodies. Among anti-HBc positive patients, 11% (7\/65) had HBs Ag and 5% (3\/65) were positive for anti-hepatitis D virus (HDV) antibodies. The prevalence of anti-hepatitis C virus (HCV) antibodies was 0.7% (4\/562). The seroprevalence of anti-HAV, HEV IgG, anti-HBc antibodies, and HBs Ag increased with age.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The present study confirms a high seroprevalence of HAV infection among the examined population and reveals high levels of endemicity for HEV in the region. Planned vaccination policies against HAV should be considered in all parts of Iran. In addition, improvements on public sanitation and hygiene management of drinking water sources for the studied area are recommended.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12879-019-4661-4","type":"journal-article","created":{"date-parts":[[2019,12,3]],"date-time":"2019-12-03T06:03:11Z","timestamp":1575352991000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Seroprevalence of viral hepatitis A, B, C, D and E viruses in the Hormozgan province southern Iran"],"prefix":"10.1186","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1691-6123","authenticated-orcid":false,"given":"Mohammad Amin","family":"Behzadi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9211-6160","authenticated-orcid":false,"given":"Victor Hugo","family":"Leyva-Grado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0988-0852","authenticated-orcid":false,"given":"Mandana","family":"Namayandeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5853-1494","authenticated-orcid":false,"given":"Atoosa","family":"Ziyaeyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0895-6782","authenticated-orcid":false,"given":"Roya","family":"Feyznezhad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5596-2384","authenticated-orcid":false,"given":"Hedayat","family":"Dorzaban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7034-1236","authenticated-orcid":false,"given":"Marzieh","family":"Jamalidoust","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9371-7518","authenticated-orcid":false,"given":"Mazyar","family":"Ziyaeyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,12,3]]},"reference":[{"issue":"S1","key":"4661_CR1","doi-asserted-by":"publisher","first-page":"S164","DOI":"10.1002\/hep.21052","volume":"43","author":"A Martin","year":"2006","unstructured":"Martin A, Lemon SM. 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