{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T10:53:34Z","timestamp":1790333614304,"version":"4.1.0"},"reference-count":86,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,12,26]],"date-time":"2019-12-26T00:00:00Z","timestamp":1577318400000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","award":["734548"],"award-info":[{"award-number":["734548"]}],"id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>The European Commission (EC) Horizon 2020 (H2020)-funded ZIKAlliance Consortium designed a multicentre study including pregnant women (PW), children (CH) and natural history (NH) cohorts. Clinical sites were selected over a wide geographic range within Latin America and the Caribbean, taking into account the dynamic course of the ZIKV epidemic.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Recruitment to the PW cohort will take place in antenatal care clinics. PW will be enrolled regardless of symptoms and followed over the course of pregnancy, approximately every 4\u2009weeks. PW will be revisited at delivery (or after miscarriage\/abortion) to assess birth outcomes, including microcephaly and other congenital abnormalities according to the evolving definition of congenital Zika syndrome (CZS).<\/jats:p>\n                <jats:p>After birth, children will be followed for 2\u2009years in the CH cohort. Follow-up visits are scheduled at ages 1\u20133, 4\u20136, 12, and 24\u2009months to assess neurocognitive and developmental milestones. In addition, a NH cohort for the characterization of symptomatic rash\/fever illness was designed, including follow-up to capture persisting health problems.<\/jats:p>\n                <jats:p>Blood, urine, and other biological materials will be collected, and tested for ZIKV and other relevant arboviral diseases (dengue, chikungunya, yellow fever) using RT-PCR or serological methods. A virtual, decentralized biobank will be created. Reciprocal clinical monitoring has been established between partner sites.<\/jats:p>\n                <jats:p>Substudies of ZIKV seroprevalence, transmission clustering, disabilities and health economics, viral kinetics, the potential role of antibody enhancement, and co-infections will be linked to the cohort studies.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Discussion<\/jats:title>\n                <jats:p>Results of these large cohort studies will provide better risk estimates for birth defects and other developmental abnormalities associated with ZIKV infection including possible co-factors for the variability of risk estimates between other countries and regions. Additional outcomes include incidence and transmission estimates of ZIKV during and after pregnancy, characterization of short and long-term clinical course following infection and viral kinetics of ZIKV.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Study registrations<\/jats:title>\n                <jats:p><jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link> NCT03188731 (PW cohort), June 15, 2017; <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link> NCT03393286 (CH cohort), January 8, 2018; <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link> NCT03204409 (NH cohort), July 2, 2017.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12879-019-4685-9","type":"journal-article","created":{"date-parts":[[2019,12,26]],"date-time":"2019-12-26T17:02:34Z","timestamp":1577379754000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Study protocol for the multicentre cohorts of Zika virus infection in pregnant women, infants, and acute clinical cases in Latin America and the Caribbean: the ZIKAlliance consortium"],"prefix":"10.1186","volume":"19","author":[{"name":"the ZIKAlliance Clinical Study Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivian I.","family":"Avelino-Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Mayaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Tami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria C.","family":"Miranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin D.","family":"Rosenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Nacul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aluisio","family":"Segurado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moritz","family":"Pohl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Bethencourt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis A.","family":"Villar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle F. T.","family":"Viana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Rabello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Soria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia P.","family":"Salgado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Gotuzzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda G.","family":"Guzm\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro A.","family":"Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"L\u00f3pez-Gatell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Hegewisch-Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor H.","family":"Borja-Aburto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo M.","family":"Netto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola M.","family":"Saba Villarroel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Hoen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia","family":"Brasil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernesto T. A.","family":"Marques","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry","family":"Rockx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Koopmans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"de Lamballerie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8252-7444","authenticated-orcid":false,"given":"Thomas","family":"Jaenisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,12,26]]},"reference":[{"issue":"5","key":"4685_CR1","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/0035-9203(52)90042-4","volume":"46","author":"GW Dick","year":"1952","unstructured":"Dick GW, Kitchen SF, Haddow AJ. Zika virus. I. Isolations and serological specificity. Trans R Soc Trop Med Hyg. 1952;46(5):509\u201320.","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"1","key":"4685_CR2","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/0035-9203(53)90021-2","volume":"47","author":"GW Dick","year":"1953","unstructured":"Dick GW. Epidemiological notes on some viruses isolated in Uganda; yellow fever, Rift Valley fever, Bwamba fever, West Nile, Mengo, Semliki forest, Bunyamwera, Ntaya, Uganda S and Zika viruses. Trans R Soc Trop Med Hyg. 1953;47(1):13\u201348.","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"5","key":"4685_CR3","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/0035-9203(52)90043-6","volume":"46","author":"GW Dick","year":"1952","unstructured":"Dick GW. Zika virus. II. Pathogenicity and physical properties. Trans R Soc Trop Med Hyg. 1952;46(5):521\u201334.","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"7","key":"4685_CR4","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1056\/NEJMp1600297","volume":"374","author":"AS Fauci","year":"2016","unstructured":"Fauci AS, Morens DM. Zika virus in the Americas--yet another Arbovirus threat. N Engl J Med. 2016;374(7):601\u20134.","journal-title":"N Engl J Med"},{"issue":"6297","key":"4685_CR5","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1126\/science.aag0219","volume":"353","author":"N. M. Ferguson","year":"2016","unstructured":"Ferguson NM, Cucunuba ZM, Dorigatti I, Nedjati-Gilani GL, Donnelly CA, Basanez MG, Nouvellet P, Lessler J: EPIDEMIOLOGY. Countering the Zika epidemic in Latin America. Science 2016, 353(6297):353\u2013354.","journal-title":"Science"},{"issue":"16","key":"4685_CR6","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1056\/NEJMoa1605564","volume":"375","author":"B Parra","year":"2016","unstructured":"Parra B, Lizarazo J, Jimenez-Arango JA, Zea-Vera AF, Gonzalez-Manrique G, Vargas J, Angarita JA, Zuniga G, Lopez-Gonzalez R, Beltran CL, et al. Guillain-Barre syndrome associated with Zika virus infection in Colombia. N Engl J Med. 2016;375(16):1513\u201323.","journal-title":"N Engl J Med"},{"key":"4685_CR7","doi-asserted-by":"publisher","unstructured":"Pacheco O, Beltran M, Nelson CA, Valencia D, Tolosa N, Farr SL, Padilla AV, Tong VT, Cuevas EL, Espinosa-Bode A, et al. Zika virus disease in Colombia - preliminary report. N Engl J Med. 2016. https:\/\/doi.org\/10.1056\/NEJMoa1604037.","DOI":"10.1056\/NEJMoa1604037"},{"issue":"4","key":"4685_CR8","doi-asserted-by":"publisher","first-page":"e0004636","DOI":"10.1371\/journal.pntd.0004636","volume":"10","author":"P Brasil","year":"2016","unstructured":"Brasil P, Calvet GA, Siqueira AM, Wakimoto M, de Sequeira PC, Nobre A, Quintana Mde S, Mendonca MC, Lupi O, de Souza RV, et al. Zika virus outbreak in Rio de Janeiro, Brazil: clinical characterization, epidemiological and Virological aspects. PLoS Negl Trop Dis. 2016;10(4):e0004636.","journal-title":"PLoS Negl Trop Dis"},{"issue":"3","key":"4685_CR9","doi-asserted-by":"publisher","first-page":"59","DOI":"10.15585\/mmwr.mm6503e2","volume":"65","author":"L Schuler-Faccini","year":"2016","unstructured":"Schuler-Faccini L, Ribeiro EM, Feitosa IM, Horovitz DD, Cavalcanti DP, Pessoa A, Doriqui MJ, Neri JI, Neto JM, Wanderley HY, et al. Possible association between Zika virus infection and microcephaly - Brazil, 2015. MMWR Morb Mortal Wkly Rep. 2016;65(3):59\u201362.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"4","key":"4685_CR10","doi-asserted-by":"publisher","first-page":"601","DOI":"10.2105\/AJPH.2016.303113","volume":"106","author":"MG Teixeira","year":"2016","unstructured":"Teixeira MG, Costa Mda C, de Oliveira WK, Nunes ML, Rodrigues LC. The epidemic of Zika virus-related microcephaly in Brazil: detection, control, etiology, and future scenarios. Am J Public Health. 2016;106(4):601\u20135.","journal-title":"Am J Public Health"},{"issue":"16","key":"4685_CR11","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.1056\/NEJMp1602708","volume":"374","author":"N Broutet","year":"2016","unstructured":"Broutet N, Krauer F, Riesen M, Khalakdina A, Almiron M, Aldighieri S, Espinal M, Low N, Dye C. Zika virus as a cause of neurologic disorders. N Engl J Med. 2016;374(16):1506\u20139.","journal-title":"N Engl J Med"},{"issue":"10027","key":"4685_CR12","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1016\/S0140-6736(16)00562-6","volume":"387","author":"Van-Mai Cao-Lormeau","year":"2016","unstructured":"Cao-Lormeau VM, Blake A, Mons S, Lastere S, Roche C, Vanhomwegen J, Dub T, Baudouin L, Teissier A, Larre P, et al. Guillain-Barre syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet. 2016;387(10027):1531-9.","journal-title":"The Lancet"},{"key":"4685_CR13","unstructured":"World Health Organization, \u201cWHO Director-General summarizes the outcome of the Emergency Committee regarding clusters of microcephaly and Guillain-Barr\u00e9 syndrome\u201d (WHO, Geneva, 2016); http:\/\/bit.ly\/HealthEmergency. In."},{"issue":"1","key":"4685_CR14","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1186\/s12879-016-1440-3","volume":"16","author":"T Jaenisch","year":"2016","unstructured":"Jaenisch T, Tam DT, Kieu NT, Van Ngoc T, Nam NT, Van Kinh N, Yacoub S, Chanpheaktra N, Kumar V, See LL, et al. Clinical evaluation of dengue and identification of risk factors for severe disease: protocol for a multicentre study in 8 countries. BMC Infect Dis. 2016;16(1):120.","journal-title":"BMC Infect Dis"},{"key":"4685_CR15","doi-asserted-by":"crossref","unstructured":"Messina JP, Kraemer MU, Brady OJ, Pigott DM, Shearer FM, Weiss DJ, Golding N, Ruktanonchai CW, Gething PW, Cohn E, et al. Mapping global environmental suitability for Zika virus. Elife. 2016;5:e15272.","DOI":"10.7554\/eLife.15272"},{"key":"4685_CR16","doi-asserted-by":"crossref","unstructured":"Netto EM, Moreira-Soto A, Pedroso C, Hoser C, Funk S, Kucharski AJ, Rockstroh A, Kummerer BM, Sampaio GS, Luz E, et al. High Zika Virus Seroprevalence in Salvador, Northeastern Brazil Limits the Potential for Further Outbreaks. MBio. 2017;8(6):e01390-17.","DOI":"10.1128\/mBio.01390-17"},{"issue":"11","key":"4685_CR17","doi-asserted-by":"publisher","first-page":"e0006055","DOI":"10.1371\/journal.pntd.0006055","volume":"11","author":"T Magalhaes","year":"2017","unstructured":"Magalhaes T, Braga C, Cordeiro MT, Oliveira ALS, Castanha PMS, Maciel APR, Amancio NML, Gouveia PN, Peixoto-da-Silva VJ Jr, Peixoto TFL, et al. Zika virus displacement by a chikungunya outbreak in Recife, Brazil. PLoS Negl Trop Dis. 2017;11(11):e0006055.","journal-title":"PLoS Negl Trop Dis"},{"issue":"3","key":"4685_CR18","doi-asserted-by":"publisher","first-page":"e0006239","DOI":"10.1371\/journal.pntd.0006239","volume":"12","author":"PM Saba Villarroel","year":"2018","unstructured":"Saba Villarroel PM, Nurtop E, Pastorino B, Roca Y, Drexler JF, Gallian P, Jaenisch T, Leparc-Goffart I, Priet S, Ninove L, et al. Zika virus epidemiology in Bolivia: a seroprevalence study in volunteer blood donors. PLoS Negl Trop Dis. 2018;12(3):e0006239.","journal-title":"PLoS Negl Trop Dis"},{"issue":"24","key":"4685_CR19","doi-asserted-by":"publisher","first-page":"2321","DOI":"10.1056\/NEJMoa1602412","volume":"375","author":"P Brasil","year":"2016","unstructured":"Brasil P, Pereira JP Jr, Moreira ME, Ribeiro Nogueira RM, Damasceno L, Wakimoto M, Rabello RS, Valderramos SG, Halai UA, Salles TS, et al. Zika virus infection in pregnant women in Rio de Janeiro. N Engl J Med. 2016;375(24):2321\u201334.","journal-title":"N Engl J Med"},{"issue":"10033","key":"4685_CR20","doi-asserted-by":"publisher","first-page":"2125","DOI":"10.1016\/S0140-6736(16)00651-6","volume":"387","author":"S Cauchemez","year":"2016","unstructured":"Cauchemez S, Besnard M, Bompard P, Dub T, Guillemette-Artur P, Eyrolle-Guignot D, Salje H, Van Kerkhove MD, Abadie V, Garel C, et al. Association between Zika virus and microcephaly in French Polynesia, 2013-15: a retrospective study. Lancet. 2016;387(10033):2125\u201332.","journal-title":"Lancet"},{"issue":"3","key":"4685_CR21","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/S1473-3099(17)30727-2","volume":"18","author":"TVB de Araujo","year":"2018","unstructured":"de Araujo TVB, Ximenes RAA, Miranda-Filho DB, Souza WV, Montarroyos UR, de Melo APL, Valongueiro S, de Albuquerque M, Braga C, Filho SPB, et al. Association between microcephaly, Zika virus infection, and other risk factors in Brazil: final report of a case-control study. Lancet Infect Dis. 2018;18(3):328\u201336.","journal-title":"Lancet Infect Dis"},{"issue":"10","key":"4685_CR22","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1056\/NEJMoa1600651","volume":"374","author":"J Mlakar","year":"2016","unstructured":"Mlakar J, Korva M, Tul N, Popovic M, Poljsak-Prijatelj M, Mraz J, Kolenc M, Resman Rus K, Vesnaver Vipotnik T, Fabjan Vodusek V, et al. Zika virus associated with microcephaly. N Engl J Med. 2016;374(10):951\u20138.","journal-title":"N Engl J Med"},{"issue":"10047","key":"4685_CR23","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1016\/S0140-6736(16)30883-2","volume":"388","author":"Roosecelis Brasil Martines","year":"2016","unstructured":"Martines RB, Bhatnagar J, de Oliveira Ramos AM, Davi HP, Iglezias SD, Kanamura CT, Keating MK, Hale G, Silva-Flannery L, Muehlenbachs A, et al. Pathology of congenital Zika syndrome in Brazil: a case series. Lancet. 2016;388(10047):898-904.","journal-title":"The Lancet"},{"issue":"9","key":"4685_CR24","doi-asserted-by":"publisher","first-page":"E1587","DOI":"10.1073\/pnas.1616097114","volume":"114","author":"MA Sheridan","year":"2017","unstructured":"Sheridan MA, Yunusov D, Balaraman V, Alexenko AP, Yabe S, Verjovski-Almeida S, Schust DJ, Franz AW, Sadovsky Y, Ezashi T, et al. Vulnerability of primitive human placental trophoblast to Zika virus. Proc Natl Acad Sci U S A. 2017;114(9):E1587\u201396.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7606","key":"4685_CR25","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1038\/nature18296","volume":"534","author":"FR Cugola","year":"2016","unstructured":"Cugola FR, Fernandes IR, Russo FB, Freitas BC, Dias JL, Guimaraes KP, Benazzato C, Almeida N, Pignatari GC, Romero S, et al. The Brazilian Zika virus strain causes birth defects in experimental models. Nature. 2016;534(7606):267\u201371.","journal-title":"Nature"},{"issue":"1","key":"4685_CR26","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.stem.2016.04.017","volume":"19","author":"C Li","year":"2016","unstructured":"Li C, Xu D, Ye Q, Hong S, Jiang Y, Liu X, Zhang N, Shi L, Qin CF, Xu Z. Zika virus disrupts neural progenitor development and leads to microcephaly in mice. Cell Stem Cell. 2016;19(1):120\u20136.","journal-title":"Cell Stem Cell"},{"key":"4685_CR27","doi-asserted-by":"publisher","first-page":"12204","DOI":"10.1038\/ncomms12204","volume":"7","author":"DM Dudley","year":"2016","unstructured":"Dudley DM, Aliota MT, Mohr EL, Weiler AM, Lehrer-Brey G, Weisgrau KL, Mohns MS, Breitbach ME, Rasheed MN, Newman CM, et al. A rhesus macaque model of Asian-lineage Zika virus infection. Nat Commun. 2016;7:12204.","journal-title":"Nat Commun"},{"issue":"8","key":"4685_CR28","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1089\/dna.2016.3404","volume":"35","author":"D Olagnier","year":"2016","unstructured":"Olagnier D, Muscolini M, Coyne CB, Diamond MS, Hiscott J. Mechanisms of Zika virus infection and Neuropathogenesis. DNA Cell Biol. 2016;35(8):367\u201372.","journal-title":"DNA Cell Biol"},{"issue":"3","key":"4685_CR29","doi-asserted-by":"publisher","first-page":"191","DOI":"10.2471\/BLT.16.178608","volume":"95","author":"T Jaenisch","year":"2017","unstructured":"Jaenisch T, Rosenberger KD, Brito C, Brady O, Brasil P, Marques ET. Risk of microcephaly after Zika virus infection in Brazil, 2015 to 2016. Bull World Health Organ. 2017;95(3):191\u20138.","journal-title":"Bull World Health Organ"},{"issue":"1","key":"4685_CR30","doi-asserted-by":"publisher","first-page":"e1002203","DOI":"10.1371\/journal.pmed.1002203","volume":"14","author":"F Krauer","year":"2017","unstructured":"Krauer F, Riesen M, Reveiz L, Oladapo OT, Martinez-Vega R, Porgo TV, Haefliger A, Broutet NJ, Low N, Group WHOZCW. Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barre syndrome: systematic review. PLoS Med. 2017;14(1):e1002203.","journal-title":"PLoS Med"},{"key":"4685_CR31","unstructured":"World Health Organization. Zika virus infection: update on the evidence for a causal link to congenital brain abnormalities and Guillain-Barr\u00e9 syndrome. Update of WHO Statement published on 31 March 2016. In.; 2016."},{"issue":"3","key":"4685_CR32","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1001\/jamapediatrics.2016.3982","volume":"171","author":"CA Moore","year":"2017","unstructured":"Moore CA, Staples JE, Dobyns WB, Pessoa A, Ventura CV, Fonseca EB, Ribeiro EM, Ventura LO, Neto NN, Arena JF, et al. Characterizing the pattern of anomalies in congenital Zika syndrome for pediatric clinicians. JAMA Pediatr. 2017;171(3):288\u201395.","journal-title":"JAMA Pediatr"},{"issue":"3","key":"4685_CR33","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003580","volume":"9","author":"NB Cleton","year":"2015","unstructured":"Cleton NB, Godeke GJ, Reimerink J, Beersma MF, Doorn HR, Franco L, Goeijenbier M, Jimenez-Clavero MA, Johnson BW, Niedrig M, et al. Spot the difference-development of a syndrome based protein microarray for specific serological detection of multiple flavivirus infections in travelers. PLoS Negl Trop Dis. 2015;9(3):e0003580.","journal-title":"PLoS Negl Trop Dis"},{"key":"4685_CR34","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.ebiom.2017.01.008","volume":"16","author":"SJ Wong","year":"2017","unstructured":"Wong SJ, Furuya A, Zou J, Xie X, Dupuis AP 2nd, Kramer LD, Shi PY. A multiplex microsphere immunoassay for Zika virus diagnosis. EBioMedicine. 2017;16:136\u201340.","journal-title":"EBioMedicine"},{"issue":"6","key":"4685_CR35","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1093\/cid\/ciw324","volume":"63","author":"M Culjat","year":"2016","unstructured":"Culjat M, Darling SE, Nerurkar VR, Ching N, Kumar M, Min SK, Wong R, Grant L, Melish ME. Clinical and imaging findings in an infant with Zika Embryopathy. Clin Infect Dis. 2016;63(6):805\u201311.","journal-title":"Clin Infect Dis"},{"issue":"6","key":"4685_CR36","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1007\/s00381-016-3074-6","volume":"32","author":"S Cavalheiro","year":"2016","unstructured":"Cavalheiro S, Lopez A, Serra S, Da Cunha A, da Costa MD, Moron A, Lederman HM. Microcephaly and Zika virus: neonatal neuroradiological aspects. Childs Nerv Syst. 2016;32(6):1057\u201360.","journal-title":"Childs Nerv Syst"},{"issue":"49","key":"4685_CR37","doi-asserted-by":"publisher","first-page":"1409","DOI":"10.15585\/mmwr.mm6549e1","volume":"65","author":"EL Cuevas","year":"2016","unstructured":"Cuevas EL, Tong VT, Rozo N, Valencia D, Pacheco O, Gilboa SM, Mercado M, Renquist CM, Gonzalez M, Ailes EC, et al. Preliminary report of microcephaly potentially associated with Zika virus infection during pregnancy - Colombia, January-November 2016. MMWR Morb Mortal Wkly Rep. 2016;65(49):1409\u201313.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"10015","key":"4685_CR38","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/S0140-6736(16)00006-4","volume":"387","author":"CV Ventura","year":"2016","unstructured":"Ventura CV, Maia M, Bravo-Filho V, Gois AL, Belfort R Jr. Zika virus in Brazil and macular atrophy in a child with microcephaly. Lancet. 2016;387(10015):228.","journal-title":"Lancet"},{"issue":"10037","key":"4685_CR39","doi-asserted-by":"publisher","first-page":"2502","DOI":"10.1016\/S0140-6736(16)30776-0","volume":"387","author":"CV Ventura","year":"2016","unstructured":"Ventura CV, Maia M, Dias N, Ventura LO, Belfort R Jr. Zika: neurological and ocular findings in infant without microcephaly. Lancet. 2016;387(10037):2502.","journal-title":"Lancet"},{"key":"4685_CR40","doi-asserted-by":"crossref","unstructured":"Mehrjardi MZ. \u00b7 Carteaux, G., \u00b7 Poretti, a.,\u00b7, Taheri MS, \u00b7 Bermudez, S., \u00b7 Werner, H., \u00b7 Hygino da Cruz Jr, L.C.: Neuroimaging findings of postnatally acquired Zika virus infection: a pictorial essay. Jpn J Radiol. 2017;35:341\u20139.","DOI":"10.1007\/s11604-017-0641-z"},{"issue":"47","key":"4685_CR41","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.15585\/mmwr.mm6547e2","volume":"65","author":"V van der Linden","year":"2016","unstructured":"van der Linden V, Pessoa A, Dobyns W, Barkovich AJ, Junior HV, Filho EL, Ribeiro EM, Leal MC, Coimbra PP, Aragao MF, et al. Description of 13 infants born during October 2015-January 2016 with congenital Zika virus infection without microcephaly at birth - Brazil. MMWR Morb Mortal Wkly Rep. 2016;65(47):1343\u20138.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"4685_CR42","volume-title":"Ages & stages questionnaires, third edition (ASQ-3): a parent completed child monitoring system","author":"J Squires","year":"2009","unstructured":"Squires J, Bricker D. Ages & stages questionnaires, third edition (ASQ-3): a parent completed child monitoring system. Baltimore: Paul H. Brookes Publishing Co.; 2009."},{"key":"4685_CR43","volume-title":"Bayley scales of infant and toddler development 3rd edition (Bayley-III)","author":"N Bayley","year":"2006","unstructured":"Bayley N. Bayley scales of infant and toddler development 3rd edition (Bayley-III). San Antonio: The Psychological Corporation; 2006."},{"issue":"16","key":"4685_CR44","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1056\/NEJMc1608612","volume":"376","author":"WK de Oliveira","year":"2017","unstructured":"de Oliveira WK, Carmo EH, Henriques CM, Coelho G, Vazquez E, Cortez-Escalante J, Molina J, Aldighieri S, Espinal MA, Dye C. Zika virus infection and associated neurologic disorders in Brazil. N Engl J Med. 2017;376(16):1591\u20133.","journal-title":"N Engl J Med"},{"key":"4685_CR45","unstructured":"Centers for Disease Control and Prevention Zika virus disease and Zika virus infection 2016 case definition. 2016. Available at: https:\/\/wwwn.cdc.gov\/nndss\/conditions\/zika\/case-definition\/2016\/06\/."},{"issue":"24","key":"4685_CR46","doi-asserted-by":"publisher","first-page":"2536","DOI":"10.1056\/NEJMoa0805715","volume":"360","author":"MR Duffy","year":"2009","unstructured":"Duffy MR, Chen TH, Hancock WT, Powers AM, Kool JL, Lanciotti RS, Pretrick M, Marfel M, Holzbauer S, Dubray C, et al. Zika virus outbreak on Yap Island, Federated States of Micronesia. N Engl J Med. 2009;360(24):2536\u201343.","journal-title":"N Engl J Med"},{"issue":"8","key":"4685_CR47","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.3201\/eid1408.080287","volume":"14","author":"RS Lanciotti","year":"2008","unstructured":"Lanciotti RS, Kosoy OL, Laven JJ, Velez JO, Lambert AJ, Johnson AJ, Stanfield SM, Duffy MR. Genetic and serologic properties of Zika virus associated with an epidemic, yap state, Micronesia, 2007. Emerg Infect Dis. 2008;14(8):1232\u20139.","journal-title":"Emerg Infect Dis"},{"issue":"6","key":"4685_CR48","first-page":"1085","volume":"20","author":"VM Cao-Lormeau","year":"2014","unstructured":"Cao-Lormeau VM, Roche C, Teissier A, Robin E, Berry AL, Mallet HP, Sall AA, Musso D. Zika virus, French polynesia, south pacific, 2013. Emerg Infect Dis. 2014;20(6):1085\u20136.","journal-title":"Emerg Infect Dis"},{"issue":"3","key":"4685_CR49","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1007\/s00430-015-0445-7","volume":"205","author":"Dennis Tappe","year":"2015","unstructured":"Tappe D, Perez-Giron JV, Zammarchi L, Rissland J, Ferreira DF, Jaenisch T, Gomez-Medina S, Gunther S, Bartoloni A, Munoz-Fontela C, et al. Cytokine kinetics of Zika virus-infected patients from acute to reconvalescent phase. Med Microbiol Immunol. 2016;205(3):269\u201373.","journal-title":"Medical Microbiology and Immunology"},{"key":"4685_CR50","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1186\/s12916-016-0601-y","volume":"14","author":"J-M Anaya","year":"2016","unstructured":"Anaya J-M, Ramirez-Santana C, Salgado-Castaneda I, Chang C, Ansari A, Gershwin ME. Zika virus and neurologic autoimmunity: the putative role of gangliosides. BMC Med. 2016;14:49.","journal-title":"BMC Med"},{"key":"4685_CR51","doi-asserted-by":"publisher","first-page":"9","DOI":"10.2807\/1560-7917.ES2014.19.9.20720","volume":"19","author":"E Oehler","year":"2014","unstructured":"Oehler E, Watrin L, Larre P, Leparc-Goffart I, Lastere S, valour F, Baudouin L, Mallet H, Musso D, Ghawche F. Zika virus infection complicated by Guillain-Barre syndrome--case report, French Polynesia, December 2013. Euro Surveill. 2014;19:9.","journal-title":"Euro Surveill"},{"issue":"10026","key":"4685_CR52","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1016\/S0140-6736(16)00644-9","volume":"387","author":"S Mecharles","year":"2016","unstructured":"Mecharles S, Herrmann C, Poullain P, Tran TH, Deschamps N, Mathon G, Landais A, Breurec S, Lannuzel A. Acute myelitis due to Zika virus infection. Lancet. 2016;387(10026):1481.","journal-title":"Lancet"},{"issue":"16","key":"4685_CR53","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1056\/NEJMc1602964","volume":"374","author":"G Carteaux","year":"2016","unstructured":"Carteaux G, Maquart M, Bedet A, Contou D, Brugieres P, Fourati S, Cleret de Langavant L, de Broucker T, Brun-Buisson C, Leparc-Goffart I, et al. Zika virus associated with Meningoencephalitis. N Engl J Med. 2016;374(16):1595\u20136.","journal-title":"N Engl J Med"},{"key":"4685_CR54","unstructured":"World Health Organization. (2016). Zika virus disease: interim case definitions. World Health Organization. Available at: https:\/\/apps.who.int\/iris\/handle\/10665\/204381."},{"issue":"7","key":"4685_CR55","doi-asserted-by":"publisher","first-page":"1684","DOI":"10.1111\/trf.13681","volume":"56","author":"ML Barjas-Castro","year":"2016","unstructured":"Barjas-Castro ML, Angerami RN, Cunha MS, Suzuki A, Nogueira JS, Rocco IM, Maeda AY, Vasami FG, Katz G, Boin IF, et al. Probable transfusion-transmitted Zika virus in Brazil. Transfusion. 2016;56(7):1684\u20138.","journal-title":"Transfusion"},{"issue":"14","key":"4685_CR56","doi-asserted-by":"publisher","first-page":"20761","DOI":"10.2807\/1560-7917.ES2014.19.14.20761","volume":"19","author":"D Musso","year":"2014","unstructured":"Musso D, Nhan T, Robin E, Roche C, Bierlaire D, Zisou K, Shan Yan A, Cao-Lormeau VM, Broult J. Potential for Zika virus transmission through blood transfusion demonstrated during an outbreak in French Polynesia, November 2013 to February 2014. Euro Surveill. 2014;19(14):20761.","journal-title":"Eurosurveillance"},{"issue":"7","key":"4685_CR57","doi-asserted-by":"publisher","first-page":"1907","DOI":"10.1111\/trf.13677","volume":"56","author":"MC Lanteri","year":"2016","unstructured":"Lanteri MC, Kleinman SH, Glynn SA, Musso D, Keith Hoots W, Custer BS, Sabino EC, Busch MP. Zika virus: a new threat to the safety of the blood supply with worldwide impact and implications. Transfusion. 2016;56(7):1907\u201314.","journal-title":"Transfusion"},{"issue":"8","key":"4685_CR58","doi-asserted-by":"publisher","first-page":"215","DOI":"10.15585\/mmwr.mm6508e2","volume":"65","author":"SL Hills","year":"2016","unstructured":"Hills SL, Russell K, Hennessey M, Williams C, Oster AM, Fischer M, Mead P. Transmission of Zika virus through sexual contact with travelers to areas of ongoing transmission - continental United States, 2016. MMWR Morb Mortal Wkly Rep. 2016;65(8):215\u20136.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"5","key":"4685_CR59","doi-asserted-by":"publisher","first-page":"880","DOI":"10.3201\/eid1705.101939","volume":"17","author":"BD Foy","year":"2011","unstructured":"Foy BD, Kobylinski KC, Chilson Foy JL, Blitvich BJ, Travassos da Rosa A, Haddow AD, Lanciotti RS, Tesh RB. Probable non-vector-borne transmission of Zika virus, Colorado, USA. Emerg Infect Dis. 2011;17(5):880\u20132.","journal-title":"Emerg Infect Dis"},{"key":"4685_CR60","doi-asserted-by":"publisher","first-page":"i720","DOI":"10.1136\/bmj.i720","volume":"352","author":"M McCarthy","year":"2016","unstructured":"McCarthy M. Zika virus was transmitted by sexual contact in Texas, health officials report. BMJ. 2016;352:i720.","journal-title":"BMJ"},{"key":"4685_CR61","doi-asserted-by":"crossref","unstructured":"Venturi G, Zammarchi L, Fortuna C, Remoli ME, Benedetti E, Fiorentini C, Trotta M, Rizzo C, Mantella A, Rezza G, et al. An autochthonous case of Zika due to possible sexual transmission, Florence, Italy, 2014. Euro Surveill. 2016;21(8):30148.","DOI":"10.2807\/1560-7917.ES.2016.21.8.30148"},{"key":"4685_CR62","doi-asserted-by":"crossref","unstructured":"Freour T, Mirallie S, Hubert B, Splingart C, Barriere P, Maquart M, Leparc-Goffart I. Sexual transmission of Zika virus in an entirely asymptomatic couple returning from a Zika epidemic area, France, April 2016. Euro Surveill. 2016;21(23):30254.","DOI":"10.2807\/1560-7917.ES.2016.21.23.30254"},{"key":"4685_CR63","doi-asserted-by":"crossref","unstructured":"Frank C, Cadar D, Schlaphof A, Neddersen N, Gunther S, Schmidt-Chanasit J, Tappe D. Sexual transmission of Zika virus in Germany, April 2016. Euro Surveill. 2016;21(23):30252.","DOI":"10.2807\/1560-7917.ES.2016.21.23.30252"},{"issue":"10037","key":"4685_CR64","doi-asserted-by":"publisher","first-page":"2501","DOI":"10.1016\/S0140-6736(16)30775-9","volume":"387","author":"JM Turmel","year":"2016","unstructured":"Turmel JM, Abgueguen P, Hubert B, Vandamme YM, Maquart M, Le Guillou-Guillemette H, Leparc-Goffart I. Late sexual transmission of Zika virus related to persistence in the semen. Lancet. 2016;387(10037):2501.","journal-title":"Lancet"},{"issue":"28","key":"4685_CR65","doi-asserted-by":"publisher","first-page":"716","DOI":"10.15585\/mmwr.mm6528e2","volume":"65","author":"A Davidson","year":"2016","unstructured":"Davidson A, Slavinski S, Komoto K, Rakeman J, Weiss D. Suspected female-to-male sexual transmission of Zika virus - New York City, 2016. MMWR Morb Mortal Wkly Rep. 2016;65(28):716\u20137.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"19","key":"4685_CR66","doi-asserted-by":"publisher","first-page":"1907","DOI":"10.1056\/NEJMc1610613","volume":"375","author":"S Swaminathan","year":"2016","unstructured":"Swaminathan S, Schlaberg R, Lewis J, Hanson KE, Couturier MR. Fatal Zika virus infection with secondary nonsexual transmission. N Engl J Med. 2016;375(19):1907\u20139.","journal-title":"N Engl J Med"},{"issue":"9","key":"4685_CR67","first-page":"1264","volume":"63","author":"S Matheron","year":"2016","unstructured":"Matheron S, d'Ortenzio E, Leparc-Goffart I, Hubert B, de Lamballerie X, Yazdanpanah Y. Long-lasting persistence of Zika virus in semen. Clin Infect Dis. 2016;63(9):1264.","journal-title":"Clin Infect Dis"},{"issue":"4","key":"4685_CR68","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1097\/AOG.0000000000001625","volume":"128","author":"D Meaney-Delman","year":"2016","unstructured":"Meaney-Delman D, Oduyebo T, Polen KN, White JL, Bingham AM, Slavinski SA, Heberlein-Larson L, St George K, Rakeman JL, Hills S, et al. Prolonged detection of Zika virus RNA in pregnant women. Obstet Gynecol. 2016;128(4):724\u201330.","journal-title":"Obstet Gynecol"},{"issue":"22","key":"4685_CR69","doi-asserted-by":"publisher","first-page":"2142","DOI":"10.1056\/NEJMoa1601824","volume":"374","author":"RW Driggers","year":"2016","unstructured":"Driggers RW, Ho CY, Korhonen EM, Kuivanen S, Jaaskelainen AJ, Smura T, Rosenberg A, Hill DA, DeBiasi RL, Vezina G, et al. Zika virus infection with prolonged maternal Viremia and fetal brain abnormalities. N Engl J Med. 2016;374(22):2142\u201351.","journal-title":"N Engl J Med"},{"issue":"8","key":"4685_CR70","doi-asserted-by":"publisher","first-page":"574","DOI":"10.2471\/BLT.16.171207","volume":"94","author":"RN Charrel","year":"2016","unstructured":"Charrel RN, Leparc-Goffart I, Pas S, de Lamballerie X, Koopmans M, Reusken C. Background review for diagnostic test development for Zika virus infection. Bull World Health Organ. 2016;94(8):574\u2013584D.","journal-title":"Bull World Health Organ"},{"key":"4685_CR71","doi-asserted-by":"crossref","unstructured":"Mogling R, Zeller H, Revez J, Koopmans M, group Zrl, Reusken C: Status, quality and specific needs of Zika virus (ZIKV) diagnostic capacity and capability in National Reference Laboratories for arboviruses in 30 EU\/EEA countries, May 2016. Euro Surveill. 2017;22(36):30609.","DOI":"10.2807\/1560-7917.ES.2017.22.36.30609"},{"issue":"12","key":"4685_CR72","doi-asserted-by":"publisher","first-page":"880","DOI":"10.2471\/BLT.16.175950","volume":"94","author":"VM Corman","year":"2016","unstructured":"Corman VM, Rasche A, Baronti C, Aldabbagh S, Cadar D, Reusken CB, Pas SD, Goorhuis A, Schinkel J, Molenkamp R, et al. Assay optimization for molecular detection of Zika virus. Bull World Health Organ. 2016;94(12):880\u201392.","journal-title":"Bull World Health Organ"},{"issue":"11","key":"4685_CR73","doi-asserted-by":"publisher","first-page":"3219","DOI":"10.1128\/JCM.00987-17","volume":"55","author":"R Charrel","year":"2017","unstructured":"Charrel R, Mogling R, Pas S, Papa A, Baronti C, Koopmans M, Zeller H, Leparc-Goffart I, Reusken CB. Variable sensitivity in molecular detection of Zika virus in European expert laboratories: external quality assessment, November 2016. J Clin Microbiol. 2017;55(11):3219\u201326.","journal-title":"J Clin Microbiol"},{"issue":"5","key":"4685_CR74","doi-asserted-by":"publisher","first-page":"888","DOI":"10.3201\/eid2405.171747","volume":"24","author":"C Fischer","year":"2018","unstructured":"Fischer C, Pedroso C, Mendrone A, Bispo de Filipis AM, Vallinoto ACR, Ribeiro B, Durignon EL, Marques ETA, Campos GS, Viana IFT, Levi JE, Scarpelli LE, Nogueira M, de Souza Bastos M, Souza NCS, Khouri R, Lira SMC, Komninakis SV, Baronti C, Charrel RN, K\u00fcmmerer BM, Drosten C, Brites C, de Lamballerie X, Niedrig M, Netto EM, Drexler JF. External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil. Emerg Infect Dis. 2018;24(5):888\u201392.","journal-title":"Emerg Infect Dis"},{"issue":"8","key":"4685_CR75","doi-asserted-by":"publisher","first-page":"2462","DOI":"10.1128\/JCM.00442-17","volume":"55","author":"AG L'Huillier","year":"2017","unstructured":"L'Huillier AG, Hamid-Allie A, Kristjanson E, Papageorgiou L, Hung S, Wong CF, Stein DR, Olsha R, Goneau LW, Dimitrova K, et al. Evaluation of Euroimmun anti-Zika virus IgM and IgG enzyme-linked Immunosorbent assays for Zika virus serologic testing. J Clin Microbiol. 2017;55(8):2462\u201371.","journal-title":"J Clin Microbiol"},{"issue":"2","key":"4685_CR76","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","volume":"42","author":"PA Harris","year":"2009","unstructured":"Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377\u201381.","journal-title":"J Biomed Inform"},{"key":"4685_CR77","volume-title":"Frequencia de microdefalia ao nascimento no Brasil. Periodo 1982\u20132013","author":"ECLAMC","year":"2015","unstructured":"ECLAMC. Frequencia de microdefalia ao nascimento no Brasil. Periodo 1982\u20132013. Buenos Aires: Estudio Colaborativo Latino Americano de Malforaciones Congenitales; 2015."},{"issue":"1","key":"4685_CR78","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1001\/jama.2016.19006","volume":"317","author":"MA Honein","year":"2017","unstructured":"Honein MA, Dawson AL, Petersen EE, Jones AM, Lee EH, Yazdy MM, Ahmad N, Macdonald J, Evert N, Bingham A, et al. Birth defects among fetuses and infants of US women with evidence of possible Zika virus infection during pregnancy. JAMA. 2017;317(1):59\u201368.","journal-title":"JAMA"},{"issue":"13","key":"4685_CR79","doi-asserted-by":"publisher","first-page":"366","DOI":"10.15585\/mmwr.mm6613e1","volume":"66","author":"MR Reynolds","year":"2017","unstructured":"Reynolds MR, Jones AM, Petersen EE, Lee EH, Rice ME, Bingham A, Ellington SR, Evert N, Reagan-Steiner S, Oduyebo T, et al. Vital signs: update on Zika virus-associated birth defects and evaluation of all U.S. infants with congenital Zika virus exposure - U.S. Zika pregnancy registry, 2016. MMWR Morb Mortal Wkly Rep. 2017;66(13):366\u201373.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"23","key":"4685_CR80","doi-asserted-by":"publisher","first-page":"615","DOI":"10.15585\/mmwr.mm6623e1","volume":"66","author":"CK Shapiro-Mendoza","year":"2017","unstructured":"Shapiro-Mendoza CK, Rice ME, Galang RR, Fulton AC, VanMaldeghem K, Prado MV, Ellis E, Anesi MS, Simeone RM, Petersen EE, et al. Pregnancy outcomes after maternal Zika virus infection during pregnancy - U.S. territories, January 1, 2016-April 25, 2017. MMWR Morb Mortal Wkly Rep. 2017;66(23):615\u201321.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"11","key":"4685_CR81","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1056\/NEJMoa1709481","volume":"378","author":"B Hoen","year":"2018","unstructured":"Hoen B, Schaub B, Funk AL, Ardillon V, Boullard M, Cabie A, Callier C, Carles G, Cassadou S, Cesaire R, et al. Pregnancy outcomes after ZIKV infection in French territories in the Americas. N Engl J Med. 2018;378(11):985\u201394.","journal-title":"N Engl J Med"},{"issue":"12","key":"4685_CR82","doi-asserted-by":"publisher","first-page":"e2320","DOI":"10.1371\/journal.pntd.0002320","volume":"7","author":"Thomas Jaenisch","year":"2013","unstructured":"Jaenisch T, Idams, Sakuntabhai A, Denfree, Wilder-Smith A, DengueTools: Dengue research funded by the European Commission-scientific strategies of three European dengue research consortia. PLoS Negl Trop Dis. 2013;7(12):e2320.","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"12","key":"4685_CR83","doi-asserted-by":"publisher","first-page":"e911","DOI":"10.1016\/S2214-109X(16)30255-8","volume":"4","author":"MD Van Kerkhove","year":"2016","unstructured":"Van Kerkhove MD, Reveiz L, Souza JP, Jaenisch T, Carson G, Broutet N. Working group on ZHR: harmonisation of Zika virus research protocols to address key public health concerns. Lancet Glob Health. 2016;4(12):e911\u20132.","journal-title":"Lancet Glob Health"},{"key":"4685_CR84","unstructured":"International Committee of Medical Journal Editors- ICMJE. Defining the role of authors and contributors. Available at: http:\/\/www.icmje.org\/recommendations\/browse\/roles-and-responsibilities\/defining-the-role-of-authors-and-contributors.html."},{"issue":"1","key":"4685_CR85","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1186\/s12916-018-1158-8","volume":"16","author":"KM O'Reilly","year":"2018","unstructured":"O'Reilly KM, Lowe R, Edmunds WJ, Mayaud P, Kucharski A, Eggo RM, Funk S, Bhatia D, Khan K, Kraemer MUG, et al. Projecting the end of the Zika virus epidemic in Latin America: a modelling analysis. BMC Med. 2018;16(1):180.","journal-title":"BMC Med"},{"issue":"10068","key":"4685_CR86","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/S0140-6736(16)32621-6","volume":"389","author":"AM Henao-Restrepo","year":"2017","unstructured":"Henao-Restrepo AM, Camacho A, Longini IM, Watson CH, Edmunds WJ, Egger M, Carroll MW, Dean NE, Diatta I, Doumbia M, et al. Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ca Suffit!). Lancet. 2017;389(10068):505\u201318.","journal-title":"Lancet"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-019-4685-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12879-019-4685-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-019-4685-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,25]],"date-time":"2020-12-25T00:05:30Z","timestamp":1608854730000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-019-4685-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":86,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["4685"],"URL":"https:\/\/doi.org\/10.1186\/s12879-019-4685-9","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"27 April 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 December 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All participants have signed, or will sign, an informed consent form upon participation. The study was approved by the Ethics Review Board at each participating institution:-Comite de Etica em Pesquisa, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; reference number 2.877.160\/CAAE 67410117.3.2002.5149.-Comite de Etica em Pesquisa, Hospital Sofia Feldman, Belo Horizonte, Brazil; reference number 2.549.675\/CAAE 67410117.3.3001.5132.-Comissao Nacional de Etica em Pesquisa (CONEP), Ministry of Health of Brazil; reference number 2.493.696\/CAAE 67410117.3.1001.5262.-Comite de Etica em Pesquisa, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil; reference numbers 2.195.948 \/CAAE 63567917.6.0000.0065; 2.262.420\/CAAE 74853517.0.0000.0065; 1.938.335\/CAAE 54699416.0.0000.0065.-Comite de Etica em Pesquisa, Centro de Pesquisas Aggeu Magalhaes, Fundacao Oswaldo Cruz, Recife, Brazil; reference numbers 2.777.436\/CAAE 80243817.5.0000.5190; 2.737.404\/CAAE 67410117.3.2001.5190.-Tribunal de Etica, Colegio Medico Santa Cruz, Santa Cruz, Bolivia; reference numbers 018\/2017; 019\/2017.-Comite de Etica, Hospital Clinica Kennedy Teoton, Guayaquil, Equador; reference number HCK-CEISH-17-0026.-Comite Institucional de Etica em Insvestigacion, Universidad Peruana Cayetano Heredia, Lima, Peru; reference numbers 101582\/766\u201322-17; 101582\/R-234-25-18.-Comite de Etica en Investigacion Cientifica de la Universidad Industrial de Santander, Bucaramanga, Colombia; reference number 4110.-Comission de Pesquisa y Bioetica, Universidad de Carabobo, Valencia, Venezuela; reference numbers CPBBUC-020-2017-DIC-AS; CPBBUC-008-2018-DIC-SB.-Research Ethics Committee, Instituto Nacional de Salud Publica, Cuernavaca, Mexico; reference numbers 17CEI00420160708\/13CEI1700736; 18CI17007029\/CI-620-2018; CB18\u2013133; CI-369-2017; CB17\u2013143.-National Comission of Scientific Research, Instituto Mexicano del Seguro Social, Mexico City, Mexico; reference number R-2016-785-076; R-2018-785\u201442.-Comite de Etica de la Investigacion, Instituto de Medicina Tropical \u201cPedro Kouri\u201d, La Habana, Cuba; reference numbers 25\u201318; 59\u201316; 40\u201316.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"This manuscript contains no individual person\u2019s data.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1081"}}