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Previous studies on\n                      <jats:italic>Cryptosporidium<\/jats:italic>\n                      in China have mainly focused on diarrhea sufferers, children, and immunodeficient individuals such as HIV\/AIDS patients. However, the epidemiological characteristics of\n                      <jats:italic>Cryptosporidium<\/jats:italic>\n                      in the population in rural areas remain unclear. Herein, we investigated the prevalence of, and risk factors for,\n                      <jats:italic>Cryptosporidium<\/jats:italic>\n                      in rural areas of Binyang County, Guangxi Zhuang Autonomous Region, China, and genetically characterized the\n                      <jats:italic>Cryptosporidium<\/jats:italic>\n                      isolates we obtained.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      From August to December 2016, two villages in Binyang County, Guangxi, were sampled using a random cluster sampling method. Fresh fecal samples were collected from all eligible residents (residence time\u2009&gt;\u20096\u2009months). Molecular characterization of\n                      <jats:italic>Cryptosporidium<\/jats:italic>\n                      was carried out based on its SSU rRNA, gp60, actin and hsp70 gene sequences. Fisher\u2019s exact test were conducted to assess the risk factors for\n                      <jats:italic>Cryptosporidium<\/jats:italic>\n                      infection.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 400 fecal samples were collected from 195 males (48.8%) and 205 females (51.2%). Two samples (0.5%) were positive for\n                      <jats:italic>Cryptosporidium<\/jats:italic>\n                      and were identified as\n                      <jats:italic>C. viatorum<\/jats:italic>\n                      and\n                      <jats:italic>C. occultus<\/jats:italic>\n                      respectively. Moreover, a new\n                      <jats:italic>C. viatorum<\/jats:italic>\n                      subtype XVaA3h was identified based on the sequence of the gp 60 gene.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      To our knowledge, this is the first report of\n                      <jats:italic>C. viatorum<\/jats:italic>\n                      and\n                      <jats:italic>C. occultus<\/jats:italic>\n                      infections in humans in China and of\n                      <jats:italic>C. viatorum<\/jats:italic>\n                      subtype XVaA3h. The findings provide important information on the prevalence of\n                      <jats:italic>Cryptosporidium<\/jats:italic>\n                      in the Chinese population, and expand the range of\n                      <jats:italic>Cryptosporidium<\/jats:italic>\n                      species known to infect people in China.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12879-019-4693-9","type":"journal-article","created":{"date-parts":[[2020,1,7]],"date-time":"2020-01-07T09:13:56Z","timestamp":1578388436000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["First report of Cryptosporidium viatorum and Cryptosporidium occultus in humans in China, and of the unique novel C. viatorum subtype XVaA3h"],"prefix":"10.1186","volume":"20","author":[{"given":"Ning","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhai","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongying","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujuan","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1974-0047","authenticated-orcid":false,"given":"Jianping","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,7]]},"reference":[{"key":"4693_CR1","doi-asserted-by":"publisher","first-page":"1701","DOI":"10.3389\/fmicb.2017.01701","volume":"8","author":"Y Feng","year":"2017","unstructured":"Feng Y, Xiao L. 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