{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T09:57:34Z","timestamp":1698746254060},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T00:00:00Z","timestamp":1593993600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T00:00:00Z","timestamp":1593993600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1186\/s12879-020-05211-3","type":"journal-article","created":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T12:03:44Z","timestamp":1594037024000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Gastrointestinal symptoms in invasive pneumococcal disease: a cohort study"],"prefix":"10.1186","volume":"20","author":[{"given":"Hans Kristian","family":"Floeystad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob Dag","family":"Berild","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bjoern Jardar","family":"Brandsaeter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didrik Frimann","family":"Vestrheim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dag","family":"Berild","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Are Martin","family":"Holm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,6]]},"reference":[{"issue":"5","key":"5211_CR1","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1056\/NEJMoa1500245","volume":"373","author":"S Jain","year":"2015","unstructured":"Jain S, Self WH, Wunderink RG, Fakhran S, Balk R, Bramley AM, et al. Community-acquired pneumonia requiring hospitalization among U.S. adults. N Engl J Med. 2015;373(5):415\u201327.","journal-title":"N Engl J Med"},{"issue":"2","key":"5211_CR2","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1086\/648678","volume":"50","author":"N Johansson","year":"2010","unstructured":"Johansson N, Kalin M, Tiveljung-Lindell A, Giske CG, Hedlund J. Etiology of community-acquired pneumonia: increased microbiological yield with new diagnostic methods. Clin Infect Dis. 2010;50(2):202\u20139.","journal-title":"Clin Infect Dis"},{"issue":"Suppl 5","key":"5211_CR3","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1111\/1469-0691.12461","volume":"20","author":"JJ Drijkoningen","year":"2014","unstructured":"Drijkoningen JJ, Rohde GG. Pneumococcal infection in adults: burden of disease. Clin Microbiol Infect. 2014;20(Suppl 5):45\u201351.","journal-title":"Clin Microbiol Infect"},{"issue":"5","key":"5211_CR4","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1080\/23744235.2016.1271997","volume":"49","author":"HK Floeystad","year":"2017","unstructured":"Floeystad HK, Holm A, Sandvik L, Vestrheim DF, Brandsaeter B, Berild D. Increased long-term mortality after survival of invasive pneumococcal disease: a population-based study. Infect Dis. 2017;49(5):365\u201372.","journal-title":"Infect Dis"},{"issue":"2","key":"5211_CR5","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1086\/377534","volume":"37","author":"VL Yu","year":"2003","unstructured":"Yu VL, Chiou CC, Feldman C, Ortqvist A, Rello J, Morris AJ, et al. An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome. Clin Infect Dis. 2003;37(2):230\u20137.","journal-title":"Clin Infect Dis"},{"issue":"17","key":"5211_CR6","doi-asserted-by":"publisher","first-page":"1965","DOI":"10.1001\/archinte.1997.00440380069007","volume":"157","author":"C Watanakunakorn","year":"1997","unstructured":"Watanakunakorn C, Bailey TA. Adult bacteremic pneumococcal pneumonia in a community teaching hospital, 1992-1996. A detailed analysis of 108 cases. Arch Intern Med. 1997;157(17):1965\u201371.","journal-title":"Arch Intern Med"},{"issue":"8","key":"5211_CR7","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1155\/2004\/461392","volume":"11","author":"K Weiss","year":"2004","unstructured":"Weiss K, Low DE, Cortes L, Beaupre A, Gauthier R, Gregoire P, et al. Clinical characteristics at initial presentation and impact of dual therapy on the outcome of bacteremic Streptococcus pneumoniae pneumonia in adults. Can Respir J. 2004;11(8):589\u201393.","journal-title":"Can Respir J"},{"issue":"6","key":"5211_CR8","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1007\/s10096-002-0749-6","volume":"21","author":"A Bucher","year":"2002","unstructured":"Bucher A, Muller F. Spectrum of abdominal and pelvic infections caused by pneumococci in previously healthy adult women. Eur J Clin Microbiol Infect Dis. 2002;21(6):474\u20137.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"14","key":"5211_CR9","doi-asserted-by":"publisher","first-page":"1742","DOI":"10.1001\/archinte.161.14.1742","volume":"161","author":"O Capdevila","year":"2001","unstructured":"Capdevila O, Pallares R, Grau I, Tubau F, Linares J, Ariza J, et al. Pneumococcal peritonitis in adult patients: report of 64 cases with special reference to emergence of antibiotic resistance. Arch Intern Med. 2001;161(14):1742\u20138.","journal-title":"Arch Intern Med"},{"issue":"2","key":"5211_CR10","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1086\/514670","volume":"27","author":"C Hemsley","year":"1998","unstructured":"Hemsley C, Eykyn SJ. Pneumococcal peritonitis in previously healthy adults: case report and review. Clin Infect Dis. 1998;27(2):376\u20139.","journal-title":"Clin Infect Dis."},{"issue":"1","key":"5211_CR11","doi-asserted-by":"publisher","first-page":"4","DOI":"10.3346\/jkms.2013.28.1.4","volume":"28","author":"JY Song","year":"2013","unstructured":"Song JY, Nahm MH, Moseley MA. Clinical implications of pneumococcal serotypes: invasive disease potential, clinical presentations, and antibiotic resistance. J Korean Med Sci. 2013;28(1):4\u201315.","journal-title":"J Korean Med Sci"},{"issue":"3","key":"5211_CR12","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1053\/jinf.2000.0653","volume":"40","author":"I Balakrishnan","year":"2000","unstructured":"Balakrishnan I, Crook P, Morris R, Gillespie SH. Early predictors of mortality in pneumococcal bacteraemia. J Infect. 2000;40(3):256\u201361.","journal-title":"J Infect."},{"issue":"6467","key":"5211_CR13","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1136\/bmj.290.6467.505","volume":"290","author":"WR Gransden","year":"1985","unstructured":"Gransden WR, Eykyn SJ, Phillips I. Pneumococcal bacteraemia: 325 episodes diagnosed at St Thomas's hospital. Br Med J (Clin Res Ed). 1985;290(6467):505\u20138.","journal-title":"Br Med J (Clin Res Ed)"},{"issue":"6","key":"5211_CR14","doi-asserted-by":"publisher","first-page":"e005224","DOI":"10.1136\/bmjopen-2014-005224","volume":"4","author":"HC Cruickshank","year":"2014","unstructured":"Cruickshank HC, Jefferies JM, Clarke SC. Lifestyle risk factors for invasive pneumococcal disease: a systematic review. BMJ Open. 2014;4(6):e005224.","journal-title":"BMJ Open"},{"issue":"10","key":"5211_CR15","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1136\/thoraxjnl-2015-206780","volume":"70","author":"A Torres","year":"2015","unstructured":"Torres A, Blasi F, Dartois N, Akova M. Which individuals are at increased risk of pneumococcal disease and why? Impact of COPD, asthma, smoking, diabetes, and\/or chronic heart disease on community-acquired pneumonia and invasive pneumococcal disease. Thorax. 2015;70(10):984\u20139.","journal-title":"Thorax."},{"issue":"1","key":"5211_CR16","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.jinf.2012.02.017","volume":"65","author":"AJ van Hoek","year":"2012","unstructured":"van Hoek AJ, Andrews N, Waight PA, Stowe J, Gates P, George R, et al. The effect of underlying clinical conditions on the risk of developing invasive pneumococcal disease in England. J Infect. 2012;65(1):17\u201324.","journal-title":"J Infect"},{"issue":"10","key":"5211_CR17","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1111\/aas.13236","volume":"62","author":"P Ursin Rein","year":"2018","unstructured":"Ursin Rein P, Jacobsen D, Ormaasen V, Dunlop O. Pneumococcal sepsis requiring mechanical ventilation: cohort study in 38 patients with rapid progression to septic shock. Acta Anaesthesiol Scand. 2018;62(10):1428\u201335.","journal-title":"Acta Anaesthesiol Scand"},{"issue":"3","key":"5211_CR18","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3109\/23744235.2015.1104719","volume":"48","author":"J Edman-Waller","year":"2016","unstructured":"Edman-Waller J, Ljungstrom L, Jacobsson G, Andersson R, Werner M. Systemic symptoms predict presence or development of severe sepsis and septic shock. Infect Dis. 2016;48(3):209\u201314.","journal-title":"Infect Dis"},{"issue":"23","key":"5211_CR19","doi-asserted-by":"publisher","first-page":"2235","DOI":"10.1056\/NEJMoa1703058","volume":"376","author":"CW Seymour","year":"2017","unstructured":"Seymour CW, Gesten F, Prescott HC, Friedrich ME, Iwashyna TJ, Phillips GS, et al. Time to treatment and mortality during mandated emergency Care for Sepsis. N Engl J Med. 2017;376(23):2235\u201344.","journal-title":"N Engl J Med"},{"issue":"18","key":"5211_CR20","doi-asserted-by":"publisher","first-page":"1849","DOI":"10.1056\/NEJMoa040845","volume":"351","author":"D van de Beek","year":"2004","unstructured":"van de Beek D, de Gans J, Spanjaard L, Weisfelt M, Reitsma JB, Vermeulen M. Clinical features and prognostic factors in adults with bacterial meningitis. N Engl J Med. 2004;351(18):1849\u201359.","journal-title":"N Engl J Med"},{"issue":"3","key":"5211_CR21","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1128\/CMR.00070-09","volume":"23","author":"MC Brouwer","year":"2010","unstructured":"Brouwer MC, Tunkel AR, van de Beek D. Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis. Clin Microbiol Rev. 2010;23(3):467\u201392.","journal-title":"Clin Microbiol Rev"},{"issue":"1","key":"5211_CR22","doi-asserted-by":"publisher","first-page":"33","DOI":"10.2217\/fmb.11.146","volume":"7","author":"ND Ritchie","year":"2012","unstructured":"Ritchie ND, Mitchell TJ, Evans TJ. What is different about serotype 1 pneumococci? Future Microbiol. 2012;7(1):33\u201346.","journal-title":"Future Microbiol"},{"key":"5211_CR23","doi-asserted-by":"publisher","first-page":"759","DOI":"10.7326\/0003-4819-60-5-759","volume":"60","author":"R Austrian","year":"1964","unstructured":"Austrian R, Gold J. Pneumococcal bacteremia with especial reference to BACTEREMIC pneumococcal pneumonia. Ann Intern Med. 1964;60:759\u201376.","journal-title":"Ann Intern Med"},{"issue":"5","key":"5211_CR24","doi-asserted-by":"publisher","first-page":"e1000081","DOI":"10.1371\/journal.pmed.1000081","volume":"6","author":"ZB Harboe","year":"2009","unstructured":"Harboe ZB, Thomsen RW, Riis A, Valentiner-Branth P, Christensen JJ, Lambertsen L, et al. Pneumococcal serotypes and mortality following invasive pneumococcal disease: a population-based cohort study. PLoS Med. 2009;6(5):e1000081.","journal-title":"PLoS Med"},{"issue":"6","key":"5211_CR25","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1086\/655828","volume":"51","author":"DM Weinberger","year":"2010","unstructured":"Weinberger DM, Harboe ZB, Sanders EA, Ndiritu M, Klugman KP, Ruckinger S, et al. Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis. Clin Infect Dis. 2010;51(6):692\u20139.","journal-title":"Clin Infect Dis"},{"issue":"2","key":"5211_CR26","doi-asserted-by":"publisher","first-page":"e29-e","DOI":"10.4081\/idr.2012.e29","volume":"4","author":"F Cobo","year":"2012","unstructured":"Cobo F, Cabezas-Fern\u00e1ndez MT, Cabeza-Barrera MI. Streptococcus pneumoniae bacteremia: clinical and microbiological epidemiology in a health area of Southern Spain. Infect Dis Rep. 2012;4(2):e29-e.","journal-title":"Infect Dis Rep"},{"issue":"5","key":"5211_CR27","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1016\/j.genm.2010.09.005","volume":"7","author":"AP Pietropaoli","year":"2010","unstructured":"Pietropaoli AP, Glance LG, Oakes D, Fisher SG. Gender differences in mortality in patients with severe sepsis or septic shock. Gend Med. 2010;7(5):422\u201337.","journal-title":"Gend Med"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-020-05211-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12879-020-05211-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-020-05211-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,7]],"date-time":"2020-07-07T06:54:11Z","timestamp":1594104851000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-020-05211-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,6]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["5211"],"URL":"https:\/\/doi.org\/10.1186\/s12879-020-05211-3","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,6]]},"assertion":[{"value":"1 March 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 June 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 July 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Ethics approval was received from the Regional Ethic Committee in Oslo, South-Eastern Norway, before the study started in 1993. As there was no Regional Ethic Committee register of projects at the time, there is no reference number. The study was re-approved by the director of the Regional Ethic Committee in South-Eastern Norway in 2015, Knut W. Ruyter.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"479"}}