{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T18:21:09Z","timestamp":1791570069718,"version":"4.3.4"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T00:00:00Z","timestamp":1621987200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T00:00:00Z","timestamp":1621987200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p><jats:italic>Mycoplasma genitalium<\/jats:italic> (MG) is an emerging sexually transmitted infection (STI) for whose management remains controversial. We aimed to assess the prevalence and risk factors of MG infection in patients attending an STI clinic in Reunion Island.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Between January 2017 and December 2018, all patients attending the Saint-Pierre STI clinic in Reunion Island were screened for MG, <jats:italic>Chlamydia trachomatis<\/jats:italic> (CT) and <jats:italic>Neisseria gonorrhoeae<\/jats:italic> (NG). Urogenital, pharyngeal and\/or anal samples were collected based on sexual behaviour and analysed by triplex PCR. Risk factors were identified using a Poisson regression for binary outcome.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Among 2069 screened subjects, the overall prevalence of MG was 4.88% [95% Confidence Interval (CI) 3.98\u20135.93]. The prevalence of urogenital MG was 4.38%, with women being more affected than men (5.33% vs 3.22%, prevalence ratio (PR) 1.66, <jats:italic>p\u2009=\u20090.02<\/jats:italic>). The prevalence of anal MG was 3.06% and that of pharyngeal MG was 0.61%, with men being more affected in both cases. Infection with MG was independently associated with multiple partners (6\u201310 partners: adjusted prevalence ratio-aPR 2.55, <jats:italic>p\u2009&lt;\u20090.048<\/jats:italic>; &gt;\u200910 partners: aPR 4.33, <jats:italic>p\u2009&lt;\u20090.004<\/jats:italic>), previous history of STI (aPR 1.89, <jats:italic>p\u2009=\u20090.026<\/jats:italic>), non-use of condoms (aPR 2.56, <jats:italic>p\u2009&lt;\u20090.003<\/jats:italic>) and co-infection with CT (aPR 2.56, <jats:italic>p\u2009&lt;\u20090.017<\/jats:italic>).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Compared to other countries, the prevalence of MG is high in Reunion Island, especially in women aged under 25\u2009years, and co-infection with CT is common. Routine MG screening and treatment should be performed in at-risk women and co-infection with MG should be considered when deciding on treatment for CT, particularly in regions where azithromycin is still in use.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12879-021-06193-6","type":"journal-article","created":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T20:03:20Z","timestamp":1622059400000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Prevalence and risk factors of Mycoplasma genitalium infection in patients attending a sexually transmitted infection clinic in Reunion Island: a cross-sectional study (2017\u20132018)"],"prefix":"10.1186","volume":"21","author":[{"given":"Roxane","family":"Begnis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Bouscaren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loic","family":"Raffray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile Saint Pastou","family":"Terrier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanny","family":"Andry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malik","family":"Boukerrou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yatrika","family":"Koumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Pierre","family":"Moiton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Gerardin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3962-8869","authenticated-orcid":false,"given":"Antoine","family":"Bertolotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,5,26]]},"reference":[{"key":"6193_CR1","first-page":"738","volume":"41","author":"N Ndeikoundam","year":"2016","unstructured":"Ndeikoundam N, Viriot D, Fournet N, De Barbeyrac B, Goubard A, Dupin N, et al. Les infections sexuellement transmissibles bact\u00e9riennes en France: situation en 2015 et \u00e9volutions r\u00e9centes. Bull Epidemiol Hebd. 2016;41:738\u201344.","journal-title":"Bull Epidemiol Hebd"},{"issue":"3","key":"6193_CR2","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1093\/cid\/civ312","volume":"61","author":"R Lis","year":"2015","unstructured":"Lis R, Rowhani-Rahbar A, Manhart LE. Mycoplasma genitalium infection and female reproductive tract disease: a meta-analysis. Clin Infect Dis. 2015;61(3):418\u201326. https:\/\/doi.org\/10.1093\/cid\/civ312.","journal-title":"Clin Infect Dis"},{"issue":"9","key":"6193_CR3","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.medmal.2012.05.006","volume":"42","author":"C Cazanave","year":"2012","unstructured":"Cazanave C, Manhart LE, B\u00e9b\u00e9ar C. Mycoplasma genitalium, an emerging sexually transmitted pathogen. 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Int J STD AIDS. 2019;30(10):938\u201350. https:\/\/doi.org\/10.1177\/0956462419825948.","journal-title":"Int J STD AIDS"},{"issue":"9","key":"6193_CR6","doi-asserted-by":"publisher","first-page":"1389","DOI":"10.1093\/cid\/civ644","volume":"61","author":"A Lau","year":"2015","unstructured":"Lau A, Bradshaw CS, Lewis D, Fairley CK, Chen MY, Kong FYS, et al. The efficacy of azithromycin for the treatment of urogenital Mycoplasma genitalium: a systematic review and meta-analysis. Clin Infect Dis. 2015;61(9):1389\u201399. https:\/\/doi.org\/10.1093\/cid\/civ644.","journal-title":"Clin Infect Dis"},{"issue":"10","key":"6193_CR7","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1111\/jdv.13849","volume":"30","author":"JS Jensen","year":"2016","unstructured":"Jensen JS, Cusini M, Gomberg M, Moi H. 2016 European guideline on Mycoplasma genitalium infections. J Eur Acad Dermatol Venereol. 2016;30(10):1650\u20136. https:\/\/doi.org\/10.1111\/jdv.13849.","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"3","key":"6193_CR8","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1136\/sti.2006.022970","volume":"83","author":"B Andersen","year":"2007","unstructured":"Andersen B, Sokolowski I, \u00d8stergaard L, M\u00f8ller JK, Olesen F, Jensen JS. Mycoplasma genitalium: prevalence and behavioural risk factors in the general population. Sex Transm Infect. 2007;83(3):237\u201341. https:\/\/doi.org\/10.1136\/sti.2006.022970.","journal-title":"Sex Transm Infect"},{"issue":"1","key":"6193_CR9","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s12879-020-4831-4","volume":"20","author":"K Jansen","year":"2020","unstructured":"Jansen K, Steffen G, Potthoff A, Schuppe AK, Beer D, Jessen H, et al. 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Occurrence of Mycoplasma genitalium in the peritoneal fluid of fertile and infertile women with detailed analysis among infertile women. Microb Pathog. 2019;129:183\u20136. https:\/\/doi.org\/10.1016\/j.micpath.2019.02.006.","journal-title":"Microb Pathog"},{"issue":"12","key":"6193_CR12","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1086\/593188","volume":"47","author":"JS Jensen","year":"2008","unstructured":"Jensen JS, Bradshaw CS, Tabrizi SN, Fairley CK, Hamasuna R. Azithromycin treatment failure in Mycoplasma genitalium\u2013positive patients with nongonococcal urethritis is associated with induced macrolide resistance. Clin Infect Dis. 2008;47(12):1546\u201353. https:\/\/doi.org\/10.1086\/593188.","journal-title":"Clin Infect Dis"},{"key":"6193_CR13","first-page":"1","volume-title":"Rapport Annuel d\u2019activit\u00e9s","author":"C B\u00e9b\u00e9ar","year":"2018","unstructured":"B\u00e9b\u00e9ar C, Ber\u00e7ot B, Dupin N. 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Available from: URL: https:\/\/www.cnr-ist.fr\/ressources\/editeur\/rapport_CNR_IST_2018.pdf."}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-021-06193-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12879-021-06193-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-021-06193-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T20:05:58Z","timestamp":1622059558000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06193-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,26]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["6193"],"URL":"https:\/\/doi.org\/10.1186\/s12879-021-06193-6","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,26]]},"assertion":[{"value":"15 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 May 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Oral informed consent was obtained from all participants and written informed consent was obtained from a parent or guardian for participants under 18\u2009years old. The ethical character of oral consent alone for this study on totally anonymous collected data was approved by the Ethic Committee for research of the CHU R\u00e9union. In accordance with French regulations, this study did not require a <i>Comit\u00e9 de Protection des Personnes<\/i> (article R1121\u20131, decree n\u00b02017\u2013884 of 9 May 2018 - art.2), but was registered with the National Institute of Health Data under the number MR 0614041119. This study was conducted according to the Declaration of Helsinki and the reference methodology MR-004 of the National Commission for Information Technology and Liberties (CNIL).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"482"}}