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Patients with hematological diseases who suffered from <jats:italic>Aeromona<\/jats:italic>s bacteremia during January 2002 to December 2020 were enrolled in this study.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 63 patients who developed <jats:italic>Aeromonas<\/jats:italic> bacteremia were enrolled in the study, and 91.9% of patients were neutropenic at the onset of BSIs. The major complications were skin and soft tissue infection (SSTI) (22.2%), followed by gastroenteritis (19.0%) and pneumonia (14.3%). High carbapenem resistance rates (70.8% for imipenem, 71.4% for meropenem) were note among the cases. Furthermore, <jats:italic>Aeromonas<\/jats:italic> strains isolated from five individuals developed resistance to quinolone, \u03b2-lactams and tigecycline during the therapy. The 30-day mortality rate was 15.9%, while bacteremia with SSTI showed a much worse prognosis, with 50.0% (7\/14) of the patients dying within 30 days of initiating the therapy. In the multivariate analysis, SSTI (OR\u2009=\u200928.72; 95% CI, 1.50\u2013551.30; <jats:italic>P<\/jats:italic>\u2009=\u20090.026) and shock (OR\u2009=\u200947.58; 95% CI,1.06\u20132126.80; <jats:italic>P<\/jats:italic>\u2009=\u20090.046) were independent risk factors for mortality.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p><jats:italic>Aeromonas<\/jats:italic> bacteremia usually occurred in patients with neutropenic status, and patients with SSTIs were more likely to show a worse prognosis. Carbapenems should be avoided in patients with <jats:italic>Aeromonas<\/jats:italic> BSIs and SSTIs given high resistance rate.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12879-022-07277-7","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T10:14:58Z","timestamp":1648548898000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Clinical characteristics and risk factors of Aeromonas bloodstream infections in patients with hematological diseases"],"prefix":"10.1186","volume":"22","author":[{"given":"Chunhui","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingsong","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanqi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqing","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erlie","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shangzhu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingchang","family":"Mi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhou","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengkui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhijian","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingzhe","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sizhou","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,29]]},"reference":[{"issue":"1","key":"7277_CR1","first-page":"1","volume":"187","author":"DVD Kooij","year":"1988","unstructured":"Kooij DVD. 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The ethics committee approved the waiver of informed consent owing to the retrospective nature of the review.  All human data of patients\u2019 records were confirmed for collection in accordance with the relevant guidelines and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The consent to publishing images of the patients\/participants in an online, open-access journal was confirmed.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"303"}}