{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T15:24:45Z","timestamp":1783956285601,"version":"3.55.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T00:00:00Z","timestamp":1648512000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T00:00:00Z","timestamp":1648512000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Actinomycosis is an uncommon endogenous bacterial infection caused by <jats:italic>Actinomyces<\/jats:italic> species, characterized by the development of abscesses, tissue fibrosis, and fistulisation. It remains a diagnostic challenge, due to its similarities with diverse aetiologies\u2019 presentation, such as neoplasms, tuberculosis, or fungal infections. <jats:italic>Actinomyces bovis<\/jats:italic> is a microorganism rarely reported as a cause of human disease. Cutaneous involvement is sporadic. In this case, <jats:italic>Actinomyces bovis<\/jats:italic> was responsible for disseminated cutaneous disease in an immunosuppressed patient.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We report the case of a 69-year-old female with multiple skin masses, under immunosuppressive therapy due to ulcerative colitis. Imaging exams were compatible with multiple cutaneous abscesses in the cervicofacial region and limbs. <jats:italic>Actinomyces bovis<\/jats:italic> was isolated in culture after abscess drainage. Antimicrobial therapy with parenteral penicillin G and oral amoxicillin was administered for 6\u00a0months, with complete resolution of cutaneous lesions and no relapse of the infection.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Considering actinomycosis as a possible diagnosis in the presence of subacute\/chronic recurrent mass-like cutaneous lesions, especially in the setting of immunosuppression, may reduce the burden associated with delayed diagnosis and incorrect treatment and provide better outcomes and improvement of patient\u2019s quality of life.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12879-022-07282-w","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T11:04:06Z","timestamp":1648551846000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Disseminated cutaneous Actinomyces bovis infection in an immunocompromised host: case report and review of the literature"],"prefix":"10.1186","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3202-1688","authenticated-orcid":false,"given":"Fl\u00e1via","family":"Cunha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Lopes","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu\u00eds","family":"Trindade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00edtor","family":"Duque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,29]]},"reference":[{"key":"7282_CR1","first-page":"3071","volume-title":"Mandell, Douglas, and Bennett\u2019s principles and practice of infectious diseases-, 9th edition","author":"TA Russo","year":"2020","unstructured":"Russo TA. 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