{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:39:33Z","timestamp":1789756773274,"version":"4.0.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T00:00:00Z","timestamp":1650499200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T00:00:00Z","timestamp":1650499200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Bacillus cereus<\/jats:italic>\n                      is a Gram-positive bacterium that can be found in various natural and human-made environments. It is often involved in gastrointestinal infections and food poisoning; yet, it can rarely cause serious non-gastrointestinal tract infections.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>\n                      Here we describe a case of\n                      <jats:italic>B. cereus<\/jats:italic>\n                      cutaneous infection of a wound on the hand of a young woman from a rural area in Iran. On admission, she had no systemic symptoms other than a cutaneous lesion. The identification of the causative agent was performed using sequencing of the 16S rRNA gene of the bacteria isolated from the wound. The isolated microorganism was identified as\n                      <jats:italic>B. cereus<\/jats:italic>\n                      . Targeted antibiotic therapy with ciprofloxacin was successful.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion and conclusion<\/jats:title>\n                    <jats:p>\n                      Although non-intestinal infections caused by\n                      <jats:italic>B. cereus<\/jats:italic>\n                      are rare, it should be taken into consideration that this organism might also cause infections in other parts of the body.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12879-022-07372-9","type":"journal-article","created":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T05:06:04Z","timestamp":1650517564000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Cutaneous infection due to Bacillus cereus: a case report"],"prefix":"10.1186","volume":"22","author":[{"given":"Mohammad","family":"Esmkhani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3701-3126","authenticated-orcid":false,"given":"Saeed","family":"Shams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,4,21]]},"reference":[{"issue":"3","key":"7372_CR1","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1080\/09583150801942334","volume":"18","author":"I Swiecicka","year":"2008","unstructured":"Swiecicka I. Natural occurrence of Bacillus thuringiensis and Bacillus cereus in eukaryotic organisms: a case for symbiosis. Biocontrol Sci Technol. 2008;18(3):221\u201339.","journal-title":"Biocontrol Sci Technol"},{"issue":"4","key":"7372_CR2","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1111\/j.1462-2920.2007.01495.x","volume":"10","author":"MH Guinebreti\u00e8re","year":"2008","unstructured":"Guinebreti\u00e8re MH, Thompson FL, Sorokin A, Normand P, Dawyndt P, Ehling-Schulz M, Svensson B, Sanchis V, Nguyen-The C, Heyndrickx M. Ecological diversification in the Bacillus cereus group. Environ Microbiol. 2008;10(4):851\u201365.","journal-title":"Environ Microbiol"},{"issue":"2","key":"7372_CR3","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1111\/j.1574-6968.1997.tb12776.x","volume":"157","author":"PE Granum","year":"1997","unstructured":"Granum PE, Lund T. Bacillus cereus and its food poisoning toxins. FEMS Microbiol Lett. 1997;157(2):223\u20138.","journal-title":"FEMS Microbiol Lett"},{"issue":"4","key":"7372_CR4","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1111\/j.1574-6976.2008.00112.x","volume":"32","author":"LP Stenfors Arnesen","year":"2008","unstructured":"Stenfors Arnesen LP, Fagerlund A, Granum PE. From soil to gut: Bacillus cereus and its food poisoning toxins. FEMS Microbiol Rev. 2008;32(4):579\u2013606.","journal-title":"FEMS Microbiol Rev"},{"issue":"11","key":"7372_CR5","doi-asserted-by":"publisher","first-page":"e03032","DOI":"10.1128\/AEM.03032-19","volume":"86","author":"JM Drewnowska","year":"2020","unstructured":"Drewnowska JM, Stefanska N, Czerniecka M, Zambrowski G, Swiecicka I. Potential enterotoxicity of phylogenetically diverse Bacillus cereus sensu lato soil isolates from different geographical locations. Appl Environ Microbiol. 2020;86(11):e03032-e13019.","journal-title":"Appl Environ Microbiol"},{"issue":"2","key":"7372_CR6","first-page":"115","volume":"52","author":"NBA Pedemonte","year":"2020","unstructured":"Pedemonte NBA, Rocchetti NS, Villalba J, Tenenbaum DL, Settecase CJ, Bagilet DH, Colombo LG, Gregorini ER. Bacillus cereus bacteremia in a patient with an abdominal stab wound. Rev Argent Microbiol. 2020;52(2):115\u20137.","journal-title":"Rev Argent Microbiol"},{"issue":"10","key":"7372_CR7","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1086\/320154","volume":"32","author":"AH Gaur","year":"2001","unstructured":"Gaur AH, Patrick CC, McCullers JA, Flynn PM, Pearson TA, Razzouk BI, Thompson SJ, Shenep JL. Bacillus cereus bacteremia and meningitis in immunocompromised children. Clin Infect Dis. 2001;32(10):1456\u201362.","journal-title":"Clin Infect Dis"},{"key":"7372_CR8","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/6380929","author":"FD Aygun","year":"2016","unstructured":"Aygun FD, Aygun F, Cam H. Successful treatment of Bacillus cereus bacteremia in a patient with propionic acidemia. Case Rep Pediatr. 2016. https:\/\/doi.org\/10.1155\/2016\/6380929.","journal-title":"Case Rep Pediatr"},{"issue":"2","key":"7372_CR9","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1067\/mjd.2002.121349","volume":"47","author":"S Boulinguez","year":"2002","unstructured":"Boulinguez S, Viraben R. Cutaneous Bacillus cereus infection in an immunocompetent patient. J Am Acad Dermatol. 2002;47(2):324\u20135.","journal-title":"J Am Acad Dermatol"},{"issue":"5","key":"7372_CR10","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1002\/pdi.1950","volume":"32","author":"F Michelotti","year":"2015","unstructured":"Michelotti F, Bodansky HJ. Bacillus cereus causing widespread necrotising skin infection in a diabetic person. Pract Diabetes. 2015;32(5):169\u2013170a.","journal-title":"Pract Diabetes"},{"issue":"8638","key":"7372_CR11","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1016\/S0140-6736(89)91621-8","volume":"333","author":"K Henrickson","year":"1989","unstructured":"Henrickson K, Flynn P, Shenep J, Pui C-H. Primary cutaneous Bacillus cereus infection in neutropenic children. Lancet. 1989;333(8638):601\u20133.","journal-title":"Lancet"},{"issue":"1","key":"7372_CR12","doi-asserted-by":"publisher","first-page":"71","DOI":"10.3109\/00365549109023377","volume":"23","author":"A \u00c5kesson","year":"1991","unstructured":"\u00c5kesson A, Hedstr\u00f6um S\u00c5, Ripa T. Bacillus cereus: a significant pathogen in postoperative and post-traumatic wounds on orthopaedic wards. 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J Infect. 2005;50(1):22\u201330.","journal-title":"J Infect"},{"issue":"2","key":"7372_CR15","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1128\/CMR.00073-09","volume":"23","author":"EJ Bottone","year":"2010","unstructured":"Bottone EJ. Bacillus cereus, a volatile human pathogen. Clin Microbiol Rev. 2010;23(2):382\u201398.","journal-title":"Clin Microbiol Rev"},{"issue":"11","key":"7372_CR16","doi-asserted-by":"publisher","first-page":"4423","DOI":"10.1128\/iai.63.11.4423-4428.1995","volume":"63","author":"DJ Beecher","year":"1995","unstructured":"Beecher DJ, Schoeni JL, Wong A. Enterotoxic activity of hemolysin BL from Bacillus cereus. Infect Immun. 1995;63(11):4423\u20138.","journal-title":"Infect Immun"},{"issue":"2","key":"7372_CR17","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1308\/003588407X155761","volume":"89","author":"A Parikh","year":"2007","unstructured":"Parikh A, Hamilton S, Sivarajan V, Withey S, Butler P. Diagnostic fine-needle aspiration in postoperative wound infections is more accurate at predicting causative organisms than wound swabs. Ann R Coll Surg Engl. 2007;89(2):166\u20137.","journal-title":"Ann R Coll Surg Engl"},{"issue":"1","key":"7372_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12866-018-1372-8","volume":"19","author":"HRM Dos Santos","year":"2019","unstructured":"Dos Santos HRM, Argolo CS, Arg\u00f4lo-Filho RC, Loguercio LL. A 16S rDNA PCR-based theoretical to actual delta approach on culturable mock communities revealed severe losses of diversity information. BMC Microbiol. 2019;19(1):1\u201314.","journal-title":"BMC Microbiol"},{"key":"7372_CR19","unstructured":"Clinical and Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing; 30th ed. CLSI supplement M45-A. 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Ann Clin Microbiol Antimicrob. 2015;14(1):1\u20137.","journal-title":"Ann Clin Microbiol Antimicrob"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-022-07372-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12879-022-07372-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-022-07372-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T17:05:09Z","timestamp":1650560709000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-022-07372-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,21]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["7372"],"URL":"https:\/\/doi.org\/10.1186\/s12879-022-07372-9","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,21]]},"assertion":[{"value":"4 October 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 April 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was reviewed and approved by the Medical Ethics Committee of Qom University of Medical Sciences (code: IR.MUQ.REC.1400.117).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report. A copy of the written consent is available for review by the Editor of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"393"}}