{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T10:57:21Z","timestamp":1779188241552,"version":"3.51.4"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["Process n\u00ba 2018\/03700-7"],"award-info":[{"award-number":["Process n\u00ba 2018\/03700-7"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objectives<\/jats:title>\n                <jats:p>To identify risk-prone areas for the spread of tuberculosis, analyze spatial variation and temporal trends of the disease in these areas and identify their determinants in a high burden city.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>An ecological study was carried out in Ribeir\u00e3o Preto, S\u00e3o Paulo, Brazil. The population was composed of pulmonary tuberculosis cases reported in the Tuberculosis Patient Control System between 2006 and 2017. Seasonal Trend Decomposition using the Loess decomposition method was used. Spatial and spatiotemporal scanning statistics were applied to identify risk areas. Spatial Variation in Temporal Trends (SVTT) was used to detect risk-prone territories with changes in the temporal trend. Finally, Pearson's Chi-square test was performed to identify factors associated with the epidemiological situation in the municipality.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Between 2006 and 2017, 1760 cases of pulmonary tuberculosis were reported in the municipality. With spatial scanning, four groups of clusters were identified with relative risks (RR) from 0.19 to 0.52, 1.73, 2.07, and 2.68 to 2.72. With the space\u2013time scan, four clusters were also identified with RR of 0.13 (2008\u20132013), 1.94 (2010\u20132015), 2.34 (2006 to 2011), and 2.84 (2014\u20132017). With the SVTT, a cluster was identified with RR 0.11, an internal time trend of growth (+\u20090.09%\/year), and an external time trend of decrease (\u2212\u00a00.06%\/year). Finally, three risk factors and three protective factors that are associated with the epidemiological situation in the municipality were identified, being: race\/brown color (OR: 1.26), without education (OR: 1.71), retired (OR: 1.35), 15\u00a0years or more of study (OR: 0.73), not having HIV (OR: 0.55) and not having diabetes (OR: 0.35).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The importance of using spatial analysis tools in identifying areas that should be prioritized for TB control is highlighted, and greater attention is necessary for individuals who fit the profile indicated as \u201cat risk\u201d for the disease.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12879-022-07500-5","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T09:03:30Z","timestamp":1654160610000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Risk-prone territories for spreading tuberculosis, temporal trends and their determinants in a high burden city from S\u00e3o Paulo State, Brazil"],"prefix":"10.1186","volume":"22","author":[{"given":"Tha\u00eds Zamboni","family":"Berra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Carlos Vieira","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Henrique","family":"Arroyo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe Mendes","family":"Delpino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliane","family":"de Almeida Crispim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan Mathias","family":"Alves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe Lima","family":"dos Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda Bruzadelli Paulino","family":"da Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcio Souza","family":"dos Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luana Seles","family":"Alves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regina C\u00e9lia","family":"Fiorati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline Aparecida","family":"Monroe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dulce","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo Alexandre","family":"Arc\u00eancio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,6,2]]},"reference":[{"key":"7500_CR1","unstructured":"World Health Organization (WHO). Global Tuberculosis Report 2021. Geneva: World Health Organization; 2019. https:\/\/www.who.int\/publications\/i\/item\/9789240037021. Accessed 12 Mar 2022."},{"key":"7500_CR2","unstructured":"Brasil. Minist\u00e9rio da Sa\u00fade. Secretaria de Vigil\u00e2ncia em Sa\u00fade. Boletim Epidemiol\u00f3gico - Tuberculose 2021, 44p. https:\/\/www.gov.br\/saude\/pt-br\/media\/pdf\/2021\/marco\/24\/boletim-tuberculose-2021_24.03. Accessed 12 Mar 2022."},{"issue":"4","key":"7500_CR3","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.1177\/0962280213485312","volume":"25","author":"P Moraga","year":"2016","unstructured":"Moraga P, Kulldorff M. Detection of spatial variations in temporal trends with a quadratic function. Stat Methods Med Res. 2016;25(4):1422\u201337.","journal-title":"Stat Methods Med Res"},{"key":"7500_CR4","volume-title":"Epidemiologic research: principles and quantitative Methods","author":"DG Kleinbaum","year":"1982","unstructured":"Kleinbaum DG, Kupper LL, Morgenstern H. Epidemiologic research: principles and quantitative Methods. 1st ed. USA: Wiley; 1982.","edition":"1"},{"key":"7500_CR5","unstructured":"Instituto Brasileiro de Geografia e Estat\u00edstica. Mapas: bases e referenciais. Rio de Janeiro: IBGE; 2010. http:\/\/mapas.ibge.gov.br\/bases-ereferenciais\/bases-cartograficas\/cartas. Accessed 12 Mar 2022."},{"issue":"1","key":"7500_CR6","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1590\/S0034-89102007000800017","volume":"41","author":"VMN Galesi","year":"2007","unstructured":"Galesi VMN. Data on tuberculosis in the state of S\u00e3o Paulo, Brazil. Rev Sa\u00fade P\u00fablica. 2007;41(1):121.","journal-title":"Rev Sa\u00fade P\u00fablica"},{"key":"7500_CR7","first-page":"3","volume":"6","author":"R Cleveland","year":"1990","unstructured":"Cleveland R, Cleveland W, McRee JE. Seasonal-trend decomposition procedure based on LOESS. J Offic Stat. 1990;6:3\u201373.","journal-title":"J Offic Stat"},{"key":"7500_CR8","unstructured":"Hyndman R, Athanasopoulos G, Bergmeir C, Caceres G, Chhay L, O'Hara-Wild M et al. Package \u2018forecast\u2019: forecasting functions for time series and linear models. https:\/\/cran.r-project.org\/web\/packages\/forecast\/forecast.pdf. Accessed 27 Oct 2020."},{"issue":"8","key":"7500_CR9","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1002\/sim.4780140809","volume":"14","author":"M Kulldorff","year":"1995","unstructured":"Kulldorff M, Nagarwalla N. Spatial disease clusters: detection and inference. Stat Med. 1995;14(8):799\u2013810.","journal-title":"Stat Med"},{"key":"7500_CR10","unstructured":"Kulldorff M. SaTScan User Guide, 2018. https:\/\/www.satscan.org\/cgi-bin\/satscan\/register.pl\/SaTScan_Users_Guide.pdf?todo=process_userguide_download. Accessed 27 Oct 2020."},{"key":"7500_CR11","unstructured":"Jaisankar R, Kesavan J. A study on spatial variations in temporal trends of dengue incidences In Tamil Nadu, India. Int J Sci Technol Res. 2019;8(09)."},{"issue":"1","key":"7500_CR12","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.2041-210X.2009.00001.x","volume":"1","author":"AF Zuur","year":"2010","unstructured":"Zuur AF, Ieno EM, Elphick CS. A protocol for data exploration to avoid common statistical problems. Methods Ecol Evol. 2010;1(1):3\u201314.","journal-title":"Methods Ecol Evol"},{"issue":"8","key":"7500_CR13","doi-asserted-by":"publisher","first-page":"2248","DOI":"10.1080\/03610918.2017.1341526","volume":"47","author":"YS Wagh","year":"2018","unstructured":"Wagh YS, Kamalja KK. Zero-inflated models and estimation in zero-inflated Poisson distribution. Commun Stat Simul Comput. 2018;47(8):2248\u201365.","journal-title":"Commun Stat Simul Comput"},{"key":"7500_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5216\/ree.v22.58883","volume":"22","author":"TZ Berra","year":"2020","unstructured":"Berra TZ, Bruce ATI, Alves YM, Campoy LT, Arroyo LH, Crispim JA, et al. Related factors, time trend and spatial association of abandonment of treatment for tuberculosis in Ribeir\u00e3o Preto-SP. Rev Eletr Enferm. 2020;22:1\u201310.","journal-title":"Rev Eletr Enferm"},{"key":"7500_CR15","unstructured":"Ribeir\u00e3o Preto. Secretaria Municipal de Sa\u00fade, Departamento de Vigil\u00e2ncia em Sa\u00fade e Planejamento. Fatores de risco relacionados \u00e0 sa\u00fade da popula\u00e7\u00e3o residente na zona urbana de Ribeir\u00e3o Preto (SP) 2008\u20132011. Ribeir\u00e3o Preto (SP). http:\/\/www.ribeiraopreto.sp.gov.br\/ssaude\/vigilancia\/vigep\/fatores-risco.pdf. Accessed 27 Oct 2020."},{"key":"7500_CR16","unstructured":"BRASIL. Minist\u00e9rio da Sa\u00fade. Secretaria de Vigil\u00e2ncia em Sa\u00fade. Departamento de Vigil\u00e2ncia das Doen\u00e7as Transmiss\u00edveis. Rede de Teste R\u00e1pido para Tuberculose no Brasil: primeiro ano da implanta\u00e7\u00e3o. Bras\u00edlia: Minist\u00e9rio da Sa\u00fade, 2015. https:\/\/portalarquivos.saude.gov.br\/images\/pdf\/2016\/janeiro\/19\/rtr-tb-15jan16-isbn-web.pdf. Accessed 27 Oct 2020."},{"issue":"2","key":"7500_CR17","first-page":"67","volume":"8","author":"TM Lima","year":"2017","unstructured":"Lima TM, Belotti NCU, Nardi SMT, Pedro HSP. GeneXpert MTB\/RIF assay for diagnosis of tuberculosis. Rev Pan-Amaz Saude. 2017;8(2):67\u201378.","journal-title":"Rev Pan-Amaz Saude"},{"key":"7500_CR18","doi-asserted-by":"publisher","first-page":"PA2779","DOI":"10.1183\/13993003.00209-2016","volume":"48","author":"W Shah","year":"2016","unstructured":"Shah W. To determine diagnostic accuracy of gene xpert and sputum Ziehl-Neelsen staining taking sputum culture as gold standard. Eur Respir J. 2016;48:PA2779.","journal-title":"Eur Respir J"},{"issue":"1","key":"7500_CR19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0169798","volume":"12","author":"P Pandey","year":"2017","unstructured":"Pandey P, Pant ND, Rijal KR, Shrestha B, Kattel S, Banjara MR, et al. Diagnostic accuracy of GeneXpert MTB\/RIF assay in comparison to conventional drug susceptibility testing method for the diagnosis of multidrug-resistant tuberculosis. PLoS ONE. 2017;12(1): e0169798.","journal-title":"PLoS ONE"},{"issue":"3","key":"7500_CR20","doi-asserted-by":"publisher","first-page":"01","DOI":"10.5380\/ce.v21i3.45339","volume":"21","author":"SM Macedo","year":"2016","unstructured":"Macedo SM, Andrade RPS, Souza CRBA, Andrade ASS, Villa TCS, Pinto ESG. Estrat\u00e9gias para capacita\u00e7\u00e3o ao cuidado em tuberculose. Cogitare Enferm. 2016;21(3):01\u20138.","journal-title":"Cogitare Enferm"},{"issue":"1","key":"7500_CR21","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1186\/s12889-021-11834-1","volume":"21","author":"J Prado-Junior","year":"2021","unstructured":"Prado-Junior J, Medronho RA. Spatial analysis of tuberculosis cure in primary care in Rio de Janeiro, Brazil. BMC Public Health. 2021;21(1):1841.","journal-title":"BMC Public Health"},{"issue":"8","key":"7500_CR22","doi-asserted-by":"publisher","first-page":"2939","DOI":"10.1590\/1413-81232020258.25692018","volume":"25","author":"BA Santos","year":"2020","unstructured":"Santos BA, Cruz RPS, Lima SVMA, Santos AD, Duque AM, Ara\u00fajo KCGM, et al. Tuberculosis among children and adolescents: an epidemiological and spatial analysis in the state of Sergipe, Brazil, 2001\u20132017. Cien Saude Colet. 2020;25(8):2939\u201348.","journal-title":"Cien Saude Colet"},{"issue":"3","key":"7500_CR23","doi-asserted-by":"publisher","DOI":"10.1590\/s1679-49742021000300006","volume":"30","author":"MS Mendes","year":"2021","unstructured":"Mendes MS, Oliveira ALS, Pimentel LMLM, Fiqueiredo TMRM, Schindler HC. Spatial analysis of tuberculosis in children under 15 years of age and socioeconomic risk: an ecological study in Para\u00edba, Brazil, 2007\u20132016. Epidemiol Serv Saude. 2021;30(3): e20201038.","journal-title":"Epidemiol Serv Saude"},{"issue":"2","key":"7500_CR24","doi-asserted-by":"publisher","DOI":"10.1590\/0034-7167-2020-0564","volume":"74","author":"HLP Andrade","year":"2021","unstructured":"Andrade HLP, Ramos ACV, Crispim JA, Santos Neto M, Arroyo LH, Arc\u00eancio RA. Spatial analysis of risk areas for the development of tuberculosis and treatment outcomes. Rev Bras Enferm. 2021;74(2): e20200564.","journal-title":"Rev Bras Enferm"},{"issue":"2","key":"7500_CR25","doi-asserted-by":"publisher","DOI":"10.1590\/1806-3713\/e20180393","volume":"45","author":"CDF Souza","year":"2019","unstructured":"Souza CDF, Paiva JPS, Silva LF, Leal TC, Magalh\u00e3es MAFM. Trends in tuberculosis mortality in Brazil (1990\u20132015): joinpoint analysis. J Bras Pneumol. 2019;45(2): e20180393.","journal-title":"J Bras Pneumol"},{"issue":"5","key":"7500_CR26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0252375","volume":"16","author":"TZ Berra","year":"2021","unstructured":"Berra TZ, Gomes D, Ramos ACV, Alves YM, Bruce ATI, Arroyo LH, et al. Effectiveness and trend forecasting of tuberculosis diagnosis after the introduction of GeneXpert in a city in south-eastern Brazil. PLoS ONE. 2021;16(5): e0252375.","journal-title":"PLoS ONE"},{"issue":"5","key":"7500_CR27","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1590\/S0037-86822012000500013","volume":"45","author":"DL Roza","year":"2012","unstructured":"Roza DL, Caccia-Bava MCGG, Martinez EZ. Spatio-temporal patterns of tuberculosis incidence in Ribeir\u00e3o Preto, State of S\u00e3o Paulo, southeast Brazil, and their relationship with social vulnerability: a Bayesian analysis. Rev Soc Bras Med Trop. 2012;45(5):607\u201315.","journal-title":"Rev Soc Bras Med Trop"},{"issue":"1","key":"7500_CR28","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1093\/eurpub\/ckaa161","volume":"31","author":"JA Santos","year":"2021","unstructured":"Santos JA, Santos DT, Arc\u00eancio RA, Nunes C. Space\u2013time clustering and temporal trends of hospitalizations due to pulmonary tuberculosis: potential strategy for assessing health care policies. Eur J Public Health. 2021;31(1):57\u201362.","journal-title":"Eur J Public Health"},{"key":"7500_CR29","doi-asserted-by":"publisher","first-page":"96","DOI":"10.11606\/s1518-8787.2021055003431","volume":"55","author":"CL Giacomet","year":"2021","unstructured":"Giacomet CL, Santos MS, Berra TZ, Alves YM, Alves LS, Costa FBP, et al. Temporal trend of tuberculosis incidence and its spatial distribution in Macap\u00e1-Amap\u00e1. Rev Saude Publica. 2021;55:96.","journal-title":"Rev Saude Publica"},{"issue":"6","key":"7500_CR30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0252712","volume":"16","author":"RA Arc\u00eancio","year":"2021","unstructured":"Arc\u00eancio RA, Berra TZ, Terena NFM, Rocha MP, Alecrim TFA, Kihara FMS, et al. Spatial clustering and temporal trend analysis of international migrants diagnosed with tuberculosis in Brazil. PLoS ONE. 2021;16(6): e0252712.","journal-title":"PLoS ONE"},{"issue":"3","key":"7500_CR31","volume":"27","author":"JN Santos","year":"2018","unstructured":"Santos JN, Sales CMM, Maciel EL. Factors associated with cure when treating tuberculosis in the state of Rio de Janeiro, Brazil, 2011\u20132014. Epidemiol Serv Saude. 2018;27(3): e2017464.","journal-title":"Epidemiol Serv Saude"},{"key":"7500_CR32","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1186\/s12889-018-5623-2","volume":"18","author":"MAM Arcoverde","year":"2018","unstructured":"Arcoverde MAM, Berra TZ, Alves LS, Santos DT, Belchior AS, Ramos ACV, et al. How do social-economic differences in urban areas affect tuberculosis mortality in a city in the tri-border region of Brazil, Paraguay and Argentina. BMC Public Health. 2018;18:795.","journal-title":"BMC Public Health"},{"key":"7500_CR33","doi-asserted-by":"publisher","first-page":"51","DOI":"10.7476\/9788575413586","volume-title":"Ra\u00e7a como quest\u00e3o: hist\u00f3ria, ci\u00eancia e identidades no Brasil","author":"MC Maio","year":"2010","unstructured":"Maio MC. Ra\u00e7a, doen\u00e7a e sa\u00fade p\u00fablica no Brasil: um debate sobre o pensamento higienista do s\u00e9culo XIX. In: Maio MC, Santos RV, editors. Ra\u00e7a como quest\u00e3o: hist\u00f3ria, ci\u00eancia e identidades no Brasil. Rio de Janeiro: Fiocruz; 2010. p. 51\u201382."},{"key":"7500_CR34","unstructured":"World Health Organization (WHO). A conceptual framework for action on the social determinants of health. Geneva: World Health Organization; 2010. https:\/\/www.who.int\/sdhconference\/resources\/ConceptualframeworkforactiononSDH_eng.pdf. Accessed 12 Mar 2022."},{"key":"7500_CR35","doi-asserted-by":"crossref","unstructured":"Rodrigues MW, Mello AGNC. Tuberculose e escolaridade: Uma revis\u00e3o da literatura. Rev Int Apoyo Inclusi\u00f3n, Logopedia, Sociedad y Multiculturalidad. 2018;4(2).","DOI":"10.17561\/riai.v4.n2.1"},{"issue":"2","key":"7500_CR36","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1038\/nrmicro.2017.128","volume":"16","author":"LCK Bell","year":"2018","unstructured":"Bell LCK, Noursadeghi M. Pathogenesis of HIV-1 and Mycobacterium tuberculosis co-infection. Nat Rev Microbiol. 2018;16(2):80\u201390.","journal-title":"Nat Rev Microbiol"},{"issue":"7","key":"7500_CR37","doi-asserted-by":"publisher","first-page":"e463","DOI":"10.1016\/S2352-3018(19)30154-7","volume":"6","author":"G Meintjes","year":"2019","unstructured":"Meintjes G, Brust JCM, Nuttall J, Maartens G. Management of active tuberculosis in adults with HIV. Lancet HIV. 2019;6(7):e463\u201374.","journal-title":"Lancet HIV"},{"key":"7500_CR38","doi-asserted-by":"crossref","unstructured":"Tornheim JA, Dooley KE. Tuberculosis associated with HIV infection. Microbiol Spectr. 2017;5(1)","DOI":"10.1128\/microbiolspec.TNMI7-0028-2016"},{"issue":"2","key":"7500_CR39","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1590\/s1806-37562017000000443","volume":"44","author":"DR Silva","year":"2018","unstructured":"Silva DR, Mu\u00f1oz-Torrico M, Duarte R, Galv\u00e3o T, Bonini EH, Arbex FF, et al. Fatores de risco para tuberculose: diabetes, tabagismo, \u00e1lcool e uso de outras drogas. J Bras Pneumol. 2018;44(2):145\u201352.","journal-title":"J Bras Pneumol"},{"key":"7500_CR40","first-page":"82","volume":"50","author":"SM Pereira","year":"2016","unstructured":"Pereira SM, Ara\u00fajo GS, Santos CAST, Oliveira MG, Barreto ML. Associa\u00e7\u00e3o entre diabetes e tuberculose: estudo caso controle. Rev Sa\u00fade P\u00fablica. 2016;50:82.","journal-title":"Rev Sa\u00fade P\u00fablica"},{"issue":"5","key":"7500_CR41","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/S1473-3099(13)70015-X","volume":"13","author":"BJ Marais","year":"2013","unstructured":"Marais BJ, L\u00f6nnroth K, Lawn SD, Migliori GB, Mwaba P, Glaziou P, et al. Tuberculosis comorbidity with communicable and non-communicable diseases: integrating health services and control efforts. Lancet Infect Dis. 2013;13(5):436\u201348.","journal-title":"Lancet Infect Dis"},{"key":"7500_CR42","doi-asserted-by":"publisher","first-page":"6196532","DOI":"10.1155\/2019\/6196532","volume":"2019","author":"B Ayelign","year":"2019","unstructured":"Ayelign B, Negash M, Genetu M, Wondmagegn T, Shibabaw T. Immunological impacts of diabetes on the susceptibility of Mycobacterium tuberculosis. J Immunol Res. 2019;2019:6196532.","journal-title":"J Immunol Res"},{"issue":"6","key":"7500_CR43","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1128\/microbiolspec.TNMI7-0023-2016","volume":"4","author":"BI Restrepo","year":"2016","unstructured":"Restrepo BI. Diabetes and tuberculosis. Microbiol Spectr. 2016;4(6):10.","journal-title":"Microbiol Spectr"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-022-07500-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12879-022-07500-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-022-07500-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T09:05:01Z","timestamp":1654160701000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-022-07500-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,2]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["7500"],"URL":"https:\/\/doi.org\/10.1186\/s12879-022-07500-5","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,2]]},"assertion":[{"value":"31 May 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 May 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"In compliance with Resolution 499\/2012 of the National Health Council, the study was approved by the Research Ethics Committee of Nursing College of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, under the Certificate of Ethical Appraisal number 87696318.3.0000.5393 issued on April 30, 2019. Consent to participate was not applicable because we worked with secondary data of cases diagnosed with tuberculosis and reported on TBWeb (tuberculosis case notification system used in the state of S\u00e3o Paulo). We declare that all applied methods were carried out following all guidelines and precepts for their validity.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"515"}}