{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:55:59Z","timestamp":1777514159104,"version":"3.51.4"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Beijing Municipal Natural Science Foundation Project","award":["No. 5202027"],"award-info":[{"award-number":["No. 5202027"]}]},{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"publisher","award":["No. 2018ZX10712001-12-2"],"award-info":[{"award-number":["No. 2018ZX10712001-12-2"]}],"id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>An outbreak of hemorrhagic fever with renal syndrome (HFRS), caused by a Hantavirus, affected nine adult males in the southwest area of Xi\u2019an in November 2020 was analyzed in this study.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Clinical and epidemiological data of HFRS patients in this outbreak were retrospectively analyzed. The whole genome of a hantavirus named 201120HV03xa (hv03xa for short) isolated from <jats:italic>Apodemus agrarius<\/jats:italic> captured in the construction site was sequenced and analyzed. In addition, nine HFRS patients were monitored for the IgG antibody against the HV N protein at 6 and 12\u00a0months, respectively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>In this study, inhalation of aerosolized excreta and contaminated food may be the main source of infection. Genome analysis and phylogenetic analysis showed that hv03xa is a reassortment strain of HTNV, having an S segment related to A16 of HTN 4, an M segment related to Q37 and Q10 of HTN 4, and an L segment related to prototype strain 76\u2013118 of HTN 7. Potential recombination was detected in the S segment of hv03xa strain. The anti-HV-IgG level of all the patients persist for at least one year after infection.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This report documented an HFRS outbreak in Xi\u2019an, China, which provided the basic data for epidemiological surveillance of endemic HTNV infection and facilitated to predict disease risk and implement prevention measures.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12879-022-07744-1","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T19:08:00Z","timestamp":1664478480000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Hemorrhagic fever with renal syndrome caused by destruction of residential area of rodent in a construction site: epidemiological investigation"],"prefix":"10.1186","volume":"22","author":[{"given":"Xiao","family":"Wei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biao","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hairui","family":"Si","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hailong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qunling","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changjun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangna","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,9,29]]},"reference":[{"issue":"11","key":"7744_CR1","doi-asserted-by":"crossref","first-page":"900","DOI":"10.3855\/jidc.9567","volume":"11","author":"E Puca","year":"2017","unstructured":"Puca E, Harxhi A, Pipero P, Qyra E, Stroni G, Muco E, Hysenaj Z, Rista E, Tosku G, Bino S. Pancreatitis in patients with hemorrhagic fever with renal syndrome: a five-year experience. J Infect Dev Ctries. 2017;11(11):900\u20133.","journal-title":"J Infect Dev Ctries"},{"issue":"4","key":"7744_CR2","volume":"9","author":"H Yu","year":"2014","unstructured":"Yu H, Jiang W, Du H, Xing Y, Bai G, Zhang Y, Li Y, Jiang H, Zhang Y, Wang J, et al. Involvement of the Akt\/NF-kappaB pathways in the HTNV-mediated increase of IL-6, CCL5, ICAM-1, and VCAM-1 in HUVECs. PLoS ONE. 2014;9(4): e93810.","journal-title":"PLoS ONE"},{"issue":"6","key":"7744_CR3","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1111\/j.1469-0691.2009.02848.x","volume":"15","author":"B Klempa","year":"2009","unstructured":"Klempa B. Hantaviruses and climate change. Clin Microbiol Infect. 2009;15(6):518\u201323.","journal-title":"Clin Microbiol Infect"},{"issue":"3","key":"7744_CR4","volume":"9","author":"HY Tian","year":"2015","unstructured":"Tian HY, Yu PB, Luis AD, Bi P, Cazelles B, Laine M, Huang SQ, Ma CF, Zhou S, Wei J, et al. Changes in rodent abundance and weather conditions potentially drive hemorrhagic fever with renal syndrome outbreaks in Xi\u2019an, China, 2005\u20132012. PLoS Negl Trop Dis. 2015;9(3): e0003530.","journal-title":"PLoS Negl Trop Dis"},{"issue":"1","key":"7744_CR5","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1186\/s12879-019-4122-0","volume":"19","author":"X Yang","year":"2019","unstructured":"Yang X, Wang C, Wu L, Jiang X, Zhang S, Jing F. Hemorrhagic fever with renal syndrome with secondary hemophagocytic lymphohistiocytosis in West China: a case report. BMC Infect Dis. 2019;19(1):492.","journal-title":"BMC Infect Dis"},{"key":"7744_CR6","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1186\/1471-2334-14-384","volume":"14","author":"S Zhang","year":"2014","unstructured":"Zhang S, Wang S, Yin W, Liang M, Li J, Zhang Q, Feng Z, Li D. Epidemic characteristics of hemorrhagic fever with renal syndrome in China, 2006\u20132012. BMC Infect Dis. 2014;14:384.","journal-title":"BMC Infect Dis"},{"issue":"Pt 10","key":"7744_CR7","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1099\/vir.0.043364-0","volume":"93","author":"C Ma","year":"2012","unstructured":"Ma C, Yu P, Nawaz M, Zuo S, Jin T, Li Y, Li J, Li H, Xu J. Hantaviruses in rodents and humans, Xi\u2019an, PR China. J Gen Virol. 2012;93(Pt 10):2227\u201336.","journal-title":"J Gen Virol"},{"issue":"2","key":"7744_CR8","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1017\/S0950268814001009","volume":"143","author":"PB Yu","year":"2015","unstructured":"Yu PB, Tian HY, Ma CF, Ma CA, Wei J, Lu XL, Wang Z, Zhou S, Li S, Dong JH, et al. Hantavirus infection in rodents and haemorrhagic fever with renal syndrome in Shaanxi province, China, 1984\u20132012. Epidemiol Infect. 2015;143(2):405\u201311.","journal-title":"Epidemiol Infect"},{"issue":"4","key":"7744_CR9","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1080\/21645515.2016.1253645","volume":"13","author":"Z Li","year":"2017","unstructured":"Li Z, Zeng H, Wang Y, Zhang Y, Cheng L, Zhang F, Lei Y, Jin B, Ma Y, Chen L. The assessment of Hantaan virus-specific antibody responses after the immunization program for hemorrhagic fever with renal syndrome in northwest China. Hum Vaccin Immunother. 2017;13(4):802\u20137.","journal-title":"Hum Vaccin Immunother"},{"key":"7744_CR10","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1186\/1471-2334-14-191","volume":"14","author":"H Du","year":"2014","unstructured":"Du H, Wang PZ, Li J, Bai L, Li H, Yu HT, Jiang W, Zhang Y, Wang JN, Bai XF. Clinical characteristics and outcomes in critical patients with hemorrhagic fever with renal syndrome. BMC Infect Dis. 2014;14:191.","journal-title":"BMC Infect Dis"},{"issue":"22","key":"7744_CR11","doi-asserted-by":"crossref","first-page":"5795","DOI":"10.12998\/wjcc.v8.i22.5795","volume":"8","author":"FQ Qiu","year":"2020","unstructured":"Qiu FQ, Li CC, Zhou JY. Hemorrhagic fever with renal syndrome complicated with aortic dissection: a case report. World J Clin Cases. 2020;8(22):5795\u2013801.","journal-title":"World J Clin Cases"},{"issue":"2","key":"7744_CR12","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1128\/CMR.00062-09","volume":"23","author":"CB Jonsson","year":"2010","unstructured":"Jonsson CB, Figueiredo LT, Vapalahti O. A global perspective on hantavirus ecology, epidemiology, and disease. Clin Microbiol Rev. 2010;23(2):412\u201341.","journal-title":"Clin Microbiol Rev"},{"issue":"3","key":"7744_CR13","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.micinf.2005.09.010","volume":"8","author":"J Klingstr\u00f6m","year":"2006","unstructured":"Klingstr\u00f6m J, Hardestam J, Lundkvist \u00c5. Dobrava, but not Saaremaa, hantavirus is lethal and induces nitric oxide production in suckling mice. Microbes Infect. 2006;8(3):728\u201337.","journal-title":"Microbes Infect"},{"issue":"Pt 11","key":"7744_CR14","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1099\/0022-1317-77-11-2677","volume":"77","author":"A Plyusnin","year":"1996","unstructured":"Plyusnin A, Vapalahti O, Vaheri A. Hantaviruses: genome structure, expression and evolution. J Gen Virol. 1996;77(Pt 11):2677\u201387.","journal-title":"J Gen Virol"},{"issue":"9","key":"7744_CR15","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1093\/infdis\/190.9.1711","volume":"190","author":"HW Lee","year":"2004","unstructured":"Lee HW, Lee PW, Johnson KM. Isolation of the etiologic agent of Korean hemorrhagic fever. J Infect Dis. 2004;190(9):1711\u201321.","journal-title":"J Infect Dis"},{"issue":"6","key":"7744_CR16","volume":"10","author":"JA Kim","year":"2016","unstructured":"Kim JA, Kim WK, No JS, Lee SH, Lee SY, Kim JH, Kho JH, Lee D, Song DH, Gu SH, et al. Genetic diversity and reassortment of hantaan virus tripartite RNA genomes in nature, the Republic of Korea. PLoS Negl Trop Dis. 2016;10(6): e0004650.","journal-title":"PLoS Negl Trop Dis"},{"issue":"2","key":"7744_CR17","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1006\/viro.2000.0630","volume":"278","author":"H Wang","year":"2000","unstructured":"Wang H, Yoshimatsu K, Ebihara H, Ogino M, Araki K, Kariwa H, Wang Z, Luo Z, Li D, Hang C, et al. Genetic diversity of hantaviruses isolated in china and characterization of novel hantaviruses isolated from Niviventer confucianus and Rattus rattus. Virology. 2000;278(2):332\u201345.","journal-title":"Virology"},{"issue":"2","key":"7744_CR18","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1099\/0022-1317-49-2-149","volume":"49","author":"PJ Padula","year":"2000","unstructured":"Padula PJ, Rossi CM, Valle MOD, Martinez PV, Colavecchia SB, Edelstein A, Miguel SDL, Rabinovich RD, Segura EL. Development and evaluation of a solid-phase enzyme immunoassay based on Andes hantavirus recombinant nucleoprotein. J Med Microbiol. 2000;49(2):149\u201355.","journal-title":"J Med Microbiol"},{"issue":"12","key":"7744_CR19","volume":"13","author":"BTD Nunes","year":"2019","unstructured":"Nunes BTD, de Mendonca MHR, Simith DB, Moraes AF, Cardoso CC, Prazeres ITE, de Aquino AA, Santos A, Queiroz ALN, Rodrigues DSG, et al. Development of RT-qPCR and semi-nested RT-PCR assays for molecular diagnosis of hantavirus pulmonary syndrome. PLoS Negl Trop Dis. 2019;13(12): e0007884.","journal-title":"PLoS Negl Trop Dis"},{"issue":"2","key":"7744_CR20","doi-asserted-by":"crossref","first-page":"389","DOI":"10.4269\/ajtmh.16-0683","volume":"96","author":"DH Song","year":"2017","unstructured":"Song DH, Kim WK, Gu SH, Lee D, Kim JA, No JS, Lee SH, Wiley MR, Palacios G, Song JW, et al. Sequence-independent, single-primer amplification next-generation sequencing of Hantaan virus cell culture-based isolates. Am J Trop Med Hyg. 2017;96(2):389\u201394.","journal-title":"Am J Trop Med Hyg"},{"key":"7744_CR21","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.virusres.2018.11.015","volume":"260","author":"S Hagele","year":"2019","unstructured":"Hagele S, Muller A, Nusshag C, Reiser J, Zeier M, Krautkramer E. Virus- and cell type-specific effects in orthohantavirus infection. Virus Res. 2019;260:102\u201313.","journal-title":"Virus Res"},{"issue":"2","key":"7744_CR22","doi-asserted-by":"crossref","first-page":"427","DOI":"10.7589\/0090-3558-47.2.427","volume":"47","author":"J Ryou","year":"2011","unstructured":"Ryou J, Lee HI, Yoo YJ, Noh YT, Yun SM, Kim SY, Shin EH, Han MG, Ju YR. Prevalence of hantavirus infection in wild rodents from five provinces in Korea, 2007. J Wildl Dis. 2011;47(2):427\u201332.","journal-title":"J Wildl Dis"},{"key":"7744_CR23","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/978-1-59745-066-9_21","volume":"444","author":"XY Zhong","year":"2008","unstructured":"Zhong XY, Holzgreve W, Huang DJ. Isolation of cell-free RNA from maternal plasma. Methods Mol Biol. 2008;444:269\u201373.","journal-title":"Methods Mol Biol"},{"issue":"5","key":"7744_CR24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0216471","volume":"14","author":"D Bolognini","year":"2019","unstructured":"Bolognini D, Bartalucci N, Mingrino A, Vannucchi AM, Magi A. NanoR: a user-friendly R package to analyze and compare nanopore sequencing data. PLoS ONE. 2019;14(5): e0216471.","journal-title":"PLoS ONE"},{"key":"7744_CR25","doi-asserted-by":"crossref","DOI":"10.1016\/j.dib.2020.106602","volume":"33","author":"A Knyazev","year":"2020","unstructured":"Knyazev A, Glushkevich A, Fesenko I. Direct RNA sequencing dataset of SMG1 KO mutant Physcomitrella (Physcomitrium patens). Data Brief. 2020;33: 106602.","journal-title":"Data Brief"},{"issue":"7","key":"7744_CR26","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1093\/molbev\/msw054","volume":"33","author":"S Kumar","year":"2016","unstructured":"Kumar S, Stecher G, Tamura K. MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets. Mol Biol Evol. 2016;33(7):1870\u20134.","journal-title":"Mol Biol Evol"},{"issue":"1","key":"7744_CR27","doi-asserted-by":"crossref","first-page":"vev003","DOI":"10.1093\/ve\/vev003","volume":"1","author":"DP Martin","year":"2015","unstructured":"Martin DP, Murrell B, Golden M, Khoosal A, Muhire B. RDP4: Detection and analysis of recombination patterns in virus genomes. Virus Evol. 2015;1(1):vev003.","journal-title":"Virus Evol"},{"issue":"6","key":"7744_CR28","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1093\/bioinformatics\/16.6.562","volume":"16","author":"D Martin","year":"2000","unstructured":"Martin D, Rybicki E. RDP: detection of recombination amongst aligned sequences. Bioinformatics. 2000;16(6):562\u20133.","journal-title":"Bioinformatics"},{"issue":"2","key":"7744_CR29","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1006\/viro.1999.0056","volume":"265","author":"M Padidam","year":"1999","unstructured":"Padidam M, Sawyer S, Fauquet CM. Possible emergence of new geminiviruses by frequent recombination. Virology. 1999;265(2):218\u201325.","journal-title":"Virology"},{"issue":"2","key":"7744_CR30","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1093\/bioinformatics\/bth490","volume":"21","author":"DP Martin","year":"2005","unstructured":"Martin DP, Williamson C, Posada D. RDP2: recombination detection and analysis from sequence alignments. Bioinformatics. 2005;21(2):260\u20132.","journal-title":"Bioinformatics"},{"issue":"5\u20136","key":"7744_CR31","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s00239-011-9473-0","volume":"73","author":"RA Bay","year":"2011","unstructured":"Bay RA, Bielawski JP. Recombination detection under evolutionary scenarios relevant to functional divergence. J Mol Evol. 2011;73(5\u20136):273\u201386.","journal-title":"J Mol Evol"},{"issue":"7","key":"7744_CR32","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1093\/bioinformatics\/16.7.573","volume":"16","author":"MJ Gibbs","year":"2000","unstructured":"Gibbs MJ, Armstrong JS, Gibbs AJ. Sister-scanning: a Monte Carlo procedure for assessing signals in recombinant sequences. Bioinformatics. 2000;16(7):573\u201382.","journal-title":"Bioinformatics"},{"issue":"2","key":"7744_CR33","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1534\/genetics.106.068874","volume":"176","author":"MF Boni","year":"2007","unstructured":"Boni MF, Posada D, Feldman MW. An exact nonparametric method for inferring mosaic structure in sequence triplets. Genetics. 2007;176(2):1035\u201347.","journal-title":"Genetics"},{"issue":"Pt 11","key":"7744_CR34","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1099\/vir.0.056374-0","volume":"94","author":"Z Zhou","year":"2013","unstructured":"Zhou Z, Deng F, Han N, Wang H, Sun S, Zhang Y, Hu Z, Rayner S. Reassortment and migration analysis of Crimean-Congo haemorrhagic fever virus. J Gen Virol. 2013;94(Pt 11):2536\u201348.","journal-title":"J Gen Virol"},{"issue":"4690","key":"7744_CR35","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1126\/science.2858126","volume":"227","author":"CS Schmaljohn","year":"1985","unstructured":"Schmaljohn CS, Hasty SE, Dalrymple JM, LeDuc JW, Lee HW, von Bonsdorff CH, Brummer-Korvenkontio M, Vaheri A, Tsai TF, Regnery HL, et al. Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome. Science. 1985;227(4690):1041\u20134.","journal-title":"Science"},{"issue":"7","key":"7744_CR36","doi-asserted-by":"crossref","first-page":"652","DOI":"10.3390\/v11070652","volume":"11","author":"J Clement","year":"2019","unstructured":"Clement J, LeDuc JW, Lloyd G, Reynes JM, McElhinney L, Van Ranst M, Lee HW. Wild rats, laboratory rats, pet rats: global Seoul hantavirus disease revisited. Viruses. 2019;11(7):652.","journal-title":"Viruses"},{"key":"7744_CR37","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1111\/1469-0691.12291","volume":"21S","author":"T Avsic-Zupanc","year":"2019","unstructured":"Avsic-Zupanc T, Saksida A, Korva M. Hantavirus infections. Clin Microbiol Infect. 2019;21S:e6\u201316.","journal-title":"Clin Microbiol Infect"},{"key":"7744_CR38","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1743-422X-2-12","volume":"2","author":"A Plyusnina","year":"2005","unstructured":"Plyusnina A, Plyusnin A. Recombinant Tula hantavirus shows reduced fitness but is able to survive in the presence of a parental virus: analysis of consecutive passages in a cell culture. Virol J. 2005;2:12.","journal-title":"Virol J"},{"issue":"8","key":"7744_CR39","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/nrmicro2614","volume":"9","author":"E Simon-Loriere","year":"2011","unstructured":"Simon-Loriere E, Holmes EC. Why do RNA viruses recombine? Nat Rev Microbiol. 2011;9(8):617\u201326.","journal-title":"Nat Rev Microbiol"},{"issue":"3","key":"7744_CR40","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1023\/A:1008199800011","volume":"21","author":"JW Song","year":"2000","unstructured":"Song JW, Baek LJ, Kim SH, Kho EY, Kim JH, Yanagihara R, Song KJ. Genetic diversity of Apodemus agrarius-borne hantaan virus in Korea. Virus Genes. 2000;21(3):227\u201332.","journal-title":"Virus Genes"},{"issue":"8937","key":"7744_CR41","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1016\/S0140-6736(94)90430-8","volume":"344","author":"JW Song","year":"1994","unstructured":"Song JW, Baek LJ, Gajdusek DC, Yanagihara R, Gavrilovskaya I, Luft BJ, Mackow ER, Hjelle B. Isolation of pathogenic hantavirus from white-footed mouse (Peromyscus leucopus). Lancet. 1994;344(8937):1637.","journal-title":"Lancet"}],"updated-by":[{"DOI":"10.1186\/s12879-022-07767-8","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T00:00:00Z","timestamp":1669766400000}}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-022-07744-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12879-022-07744-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-022-07744-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,5]],"date-time":"2022-12-05T14:46:58Z","timestamp":1670251618000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-022-07744-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,29]]},"references-count":41,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["7744"],"URL":"https:\/\/doi.org\/10.1186\/s12879-022-07744-1","relation":{"correction":[{"id-type":"doi","id":"10.1186\/s12879-022-07767-8","asserted-by":"object"}]},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,29]]},"assertion":[{"value":"19 May 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 September 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 September 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 November 2022","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1186\/s12879-022-07767-8","URL":"https:\/\/doi.org\/10.1186\/s12879-022-07767-8","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All participants signed an informed consent form prior to entering the study. The study conformed to the ethical guidelines of the 1975 Declaration of Helsinki. All human experimental protocols in this study were approved by the Ethics Committee of the PLA 63750 Hospital. All human experimental procedures were carried out in accordance with relevant guidelines and regulations. All animal experimental protocols in this study were approved by the Ethics Committee of the PLA 63750 Hospital. All animal experimental procedures were carried out in accordance with relevant guidelines and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"761"}}