{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T11:24:10Z","timestamp":1771068250525,"version":"3.50.1"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T00:00:00Z","timestamp":1693180800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T00:00:00Z","timestamp":1693180800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Zhejiang TCM Science and Technology Program of China","award":["2022ZB292"],"award-info":[{"award-number":["2022ZB292"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p><jats:italic>Talaromycosis<\/jats:italic> is a common invasive fungal disease in patients with HIV. However, its association with bone destruction is unusual in AIDS patients with talaromycosis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case Presentation<\/jats:title>\n                <jats:p>This report covers the case of a 38-year-old male AIDS patient coinfected with <jats:italic>Talaromyces marneffei<\/jats:italic> and <jats:italic>Salmonella<\/jats:italic>. The case, which involved bone destruction, was identified via metagenomic next-generation sequencing (mNGS). Following treatment with a combination of amphotericin B and piperacillin-tazobactam, the patient\u2019s elbow motion noticeably improved. Imaging findings revealed that the progression of bony destruction had halted.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Bone damage due to <jats:italic>Talaromyces marneffei<\/jats:italic> infection is infrequent in HIV-positive patients. Therefore, healthcare professionals must be vigilant for potential bone lesions associated with this type of infection. Prompt diagnosis and antimicrobial treatment are crucial.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12879-023-08554-9","type":"journal-article","created":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T09:04:40Z","timestamp":1693213480000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Osteoarticular infection caused by Talaromyces Marneffei and Salmonella in a person living with HIV: a case report"],"prefix":"10.1186","volume":"23","author":[{"given":"Lele","family":"Yu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binhai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinchuan","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hu","family":"Wan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,8,28]]},"reference":[{"issue":"5\u20136","key":"8554_CR1","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s11046-014-9737-5","volume":"177","author":"F Zhou","year":"2014","unstructured":"Zhou F, Bi X, Zou X, Xu Z, Zhang T. Retrospective analysis of 15 cases of penicilliosis marneffei in a southern China hospital. Mycopathologia. 2014;177(5\u20136):271\u20139. https:\/\/doi.org\/10.1007\/s11046-014-9737-5.","journal-title":"Mycopathologia"},{"issue":"4","key":"8554_CR2","doi-asserted-by":"publisher","first-page":"637","DOI":"10.4269\/ajtmh.1984.33.637","volume":"33","author":"P Jayanetra","year":"1984","unstructured":"Jayanetra P, Nitiyanant P, Ajello L, Padhye AA, Lolekha S, Atichartakarn V, et al. Penicilliosis marneffei in Thailand: report of five human cases. Am J Trop Med Hyg. 1984;33(4):637\u201344. https:\/\/doi.org\/10.4269\/ajtmh.1984.33.637.","journal-title":"Am J Trop Med Hyg"},{"key":"8554_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ijid.2013.12.019","volume":"23","author":"GN Liu","year":"2014","unstructured":"Liu GN, Huang JS, Zhong XN, Zhang JQ, Zou ZX, Yang ML, et al. Penicillium marneffei infection within an osteolytic lesion in an HIV-negative patient. Int J Infect Dis. 2014;23:1\u20133. https:\/\/doi.org\/10.1016\/j.ijid.2013.12.019.","journal-title":"Int J Infect Dis"},{"issue":"1","key":"8554_CR4","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/1742-6405-9-24","volume":"9","author":"M Larsson","year":"2012","unstructured":"Larsson M, Nguyen LH, Wertheim HF, Dao TT, Taylor W, Horby P, et al. Clinical characteristics and outcome of Penicillium marneffei infection among HIV-infected patients in northern Vietnam. AIDS Res Therapy. 2012;9(1):24. https:\/\/doi.org\/10.1186\/1742-6405-9-24.","journal-title":"AIDS Res Therapy"},{"issue":"5\u20136","key":"8554_CR5","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1007\/s11046-016-0107-3","volume":"182","author":"Y Ouyang","year":"2017","unstructured":"Ouyang Y, Cai S, Liang H, Cao C. Administration of Voriconazole in disseminated Talaromyces (Penicillium) Marneffei infection: a retrospective study. Mycopathologia. 2017;182(5\u20136):569\u201375. https:\/\/doi.org\/10.1007\/s11046-016-0107-3.","journal-title":"Mycopathologia"},{"key":"8554_CR6","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12879-015-0782-6","volume":"15","author":"Y Qiu","year":"2015","unstructured":"Qiu Y, Zhang J, Liu G, Zhong X, Deng J, He Z, et al. Retrospective analysis of 14 cases of disseminated Penicillium marneffei infection with osteolytic lesions. BMC Infect Dis. 2015;15:47. https:\/\/doi.org\/10.1186\/s12879-015-0782-6.","journal-title":"BMC Infect Dis"},{"issue":"10","key":"8554_CR7","first-page":"11491","volume":"13","author":"Y Bai","year":"2021","unstructured":"Bai Y, Xi D, Chen Q, Shi Z, Wen B, Zhang Q, et al. Characteristics of Talaromyces marneffei with bone destruction in Guangxi Province, China: a retrospective study. Am J Translational Res. 2021;13(10):11491\u2013500.","journal-title":"Am J Translational Res"},{"key":"8554_CR8","doi-asserted-by":"publisher","unstructured":"Tsang CC, Teng JLL, Lau SKP, Woo PCY. Rapid genomic diagnosis of fungal infections in the age of Next-Generation sequencing. J Fungi. 2021;7(8). https:\/\/doi.org\/10.3390\/jof7080636.","DOI":"10.3390\/jof7080636"},{"key":"8554_CR9","doi-asserted-by":"publisher","first-page":"987692","DOI":"10.3389\/fcimb.2022.987692","volume":"12","author":"L Liu","year":"2022","unstructured":"Liu L, Sun B, Ying W, Liu D, Wang Y, Sun J, et al. Rapid diagnosis of Talaromyces marneffei infection by metagenomic next-generation sequencing technology in a chinese cohort of inborn errors of immunity. Front Cell Infect Microbiol. 2022;12:987692. https:\/\/doi.org\/10.3389\/fcimb.2022.987692.","journal-title":"Front Cell Infect Microbiol"},{"issue":"1","key":"8554_CR10","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1186\/s12879-021-06551-4","volume":"21","author":"Q Chen","year":"2021","unstructured":"Chen Q, Qiu Y, Zeng W, Wei X, Zhang J. Metagenomic next-generation sequencing for the early diagnosis of talaromycosis in HIV-uninfected patients: five cases report. BMC Infect Dis. 2021;21(1):865. https:\/\/doi.org\/10.1186\/s12879-021-06551-4.","journal-title":"BMC Infect Dis"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-023-08554-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12879-023-08554-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-023-08554-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T20:06:30Z","timestamp":1700510790000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-023-08554-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,28]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["8554"],"URL":"https:\/\/doi.org\/10.1186\/s12879-023-08554-9","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,28]]},"assertion":[{"value":"16 February 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 August 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent for participation in this study was provided by the participant.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the individual, for the publication of any potentially identifiable images or data included in this article.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"560"}}