{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T00:17:51Z","timestamp":1771028271548,"version":"3.50.1"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T00:00:00Z","timestamp":1704672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T00:00:00Z","timestamp":1704672000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p><jats:italic>Yersinia enterocolitica<\/jats:italic> is a gram-negative zoonotic bacterial pathogen that is typically transmitted via the fecal-oral route. The most common clinical manifestation of a <jats:italic>Y. enterocolitica<\/jats:italic> infection is self-limited gastroenteritis. Although various extraintestinal manifestations of <jats:italic>Y. enterocolitica<\/jats:italic> infection have been reported, there are no reports of thyroid abscesses.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>An 89-year-old Japanese man with follicular adenoma of the left thyroid gland was admitted to our hospital with a 2-day history of fever and left neck pain. Laboratory tests revealed low levels of thyroid stimulating hormone and elevated levels of free thyroxine 4. Contrast-enhanced computed tomography showed low-attenuation areas with peripheral enhancement in the left thyroid gland. He was diagnosed with thyroid abscess and thyrotoxicosis, and treatment with intravenous piperacillin-tazobactam was initiated after collecting blood, drainage fluid, and stool samples. The isolated Gram-negative rod bacteria from blood and drainage fluid cultures was confirmed to be <jats:italic>Y. enterocolitica<\/jats:italic>. He was diagnosed with thyroid abscess and thyrotoxicosis due to be <jats:italic>Y. enterocolitica<\/jats:italic> subsp. <jats:italic>palearctica<\/jats:italic>. The piperacillin-tazobactam was replaced with levofloxacin.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>We report a novel case of a thyroid abscess associated with thyrotoxicosis caused by <jats:italic>Y. enterocolitica<\/jats:italic> subsp. <jats:italic>palearctica<\/jats:italic> in a patient with a follicular thyroid adenoma.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12879-024-08974-1","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T12:02:18Z","timestamp":1704715338000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Thyroid abscess associated with thyrotoxicosis caused by Yersinia enterocolitica subsp. palearctica in a patient with follicular adenoma of the thyroid gland"],"prefix":"10.1186","volume":"24","author":[{"given":"Takehiro","family":"Hashimoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takaaki","family":"Yahiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonoka","family":"Takakura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sakirul","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunori","family":"Kimitsuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazufumi","family":"Hiramatsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Nishizono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,1,8]]},"reference":[{"issue":"3","key":"8974_CR1","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1089\/fpd.2011.0938","volume":"9","author":"N Drummond","year":"2012","unstructured":"Drummond N, Murphy BP, Ringwood T, Prentice MB, Buckley JF, Fanning S. Yersinia enterocolitica: a brief review of the issues relating to the zoonotic pathogen, public health challenges, and the pork production chain. Foodborne Pathog Dis. 2012;9(3):179\u201389.","journal-title":"Foodborne Pathog Dis."},{"key":"8974_CR2","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1186\/1471-2334-10-122","volume":"10","author":"E Huovinen","year":"2010","unstructured":"Huovinen E, Sihvonen LM, Virtanen MJ, Haukka K, Siitonen A, Kuusi M. Symptoms and sources of Yersinia enterocolitica-infection: a case-control study. BMC Infect Dis. 2010;10:122.","journal-title":"BMC Infect Dis."},{"issue":"2","key":"8974_CR3","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1128\/CMR.10.2.257","volume":"10","author":"EJ Bottone","year":"1997","unstructured":"Bottone EJ. Yersinia enterocolitica: the charisma continues. Clin Microbiol Rev. 1997;10(2):257\u201376.","journal-title":"Clin Microbiol Rev."},{"issue":"8","key":"8974_CR4","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1016\/j.ijscr.2014.05.019","volume":"5","author":"SO Cawich","year":"2014","unstructured":"Cawich SO, Hassranah D, Naraynsingh V. Idiopathic thyroid abscess. Int J Surg Case Rep. 2014;5(8):484\u20136.","journal-title":"Int J Surg Case Rep."},{"key":"8974_CR5","doi-asserted-by":"publisher","first-page":"omx049","DOI":"10.1093\/omcr\/omx049","volume":"2017","author":"K Dv","year":"2017","unstructured":"Dv K, Gunasekaran K, Mishra AK, Iyyadurai R. Disseminated tuberculosis presenting as cold abscess of the thyroid gland-a case report. Oxf Med Case Rep. 2017;2017:omx049.","journal-title":"Oxf Med Case Rep."},{"key":"8974_CR6","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1186\/s12879-019-3808-7","volume":"19","author":"T Takehara","year":"2019","unstructured":"Takehara T, Tani T, Yajima K, Watanabe M, Otsuka Y, Koh H. First case report of thyroid abscess caused by helicobacter cinaedi presenting with thyroid storm. BMC Infect Dis. 2019;19:166.","journal-title":"BMC Infect Dis."},{"key":"8974_CR7","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1186\/s13256-023-04119-1","volume":"17","author":"Z Seyedjavadeyn","year":"2023","unstructured":"Seyedjavadeyn Z, Miratashi Yazdi SA, Samimiat A, Vahedi M. Thyrotoxicosis as a rare presentation in acute suppurative thyroiditis: a case report. J Med Case Rep. 2023;17:428.","journal-title":"J Med Case Rep."},{"key":"8974_CR8","doi-asserted-by":"publisher","first-page":"e251","DOI":"10.4158\/EP161244.CR","volume":"3","author":"VT San Martin","year":"2017","unstructured":"San Martin VT, Kausel AM, Albu JB. Haemophilus influenzae as a rare cause of acute suppurative thyroiditis with thyrotoxicosis and thyroid abscess formation in a patient with pre-existent multinodular goiter. AACE Clin Case Rep. 2017;3:e251\u20134.","journal-title":"AACE Clin Case Rep."},{"key":"8974_CR9","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1089\/thy.2006.16.307","volume":"16","author":"SA McLaughlin","year":"2006","unstructured":"McLaughlin SA, Smith SL, Meek SE. Acute suppurative thyroiditis caused by Pasteurella multocida and associated with thyrotoxicosis. Thyroid. 2006;16:307\u201310.","journal-title":"Thyroid."},{"issue":"3","key":"8974_CR10","doi-asserted-by":"publisher","first-page":"1810","DOI":"10.1128\/AEM.69.3.1810-1816.2003","volume":"69","author":"P Thoerner","year":"2003","unstructured":"Thoerner P, Bin Kingombe CI, B\u00f6gli-Stuber K, Bissig-Choisat B, Wassenaar TM, Frey J, et al. PCR detection of virulence genes in Yersinia enterocolitica and Yersinia pseudotuberculosis and investigation of virulence gene distribution. Appl Environ Microbiol. 2003;69(3):1810\u20136.","journal-title":"Appl Environ Microbiol."},{"issue":"3\u20134","key":"8974_CR11","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.ijmm.2013.10.007","volume":"304","author":"D Garzetti","year":"2014","unstructured":"Garzetti D, Susen R, Fruth A, Tietze E, Heesemann J, Rakin A. A molecular scheme for Yersinia enterocolitica patho-serotyping derived from genome-wide analysis. Int J Med Microbiol. 2014;304(3\u20134):275\u201383.","journal-title":"Int J Med Microbiol."},{"issue":"1","key":"8974_CR12","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.eimc.2011.07.017","volume":"30","author":"A F\u00e0brega","year":"2012","unstructured":"F\u00e0brega A, Vila J. Yersinia enterocolitica: pathogenesis, virulence and antimicrobial resistance. Enferm Infecc Microbiol Clin. 2012;30(1):24\u201332.","journal-title":"Enferm Infecc Microbiol Clin."},{"issue":"1","key":"8974_CR13","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1186\/s12879-020-05161-w","volume":"20","author":"MK AlYousef","year":"2020","unstructured":"AlYousef MK, Al-Sayed AA, Al Afif A, Alamoudi U, LeBlanc JM, LeBlanc R. A pain in the neck: Salmonella spp. as an unusual cause of a thyroid abscess. A case report and review of the literature. BMC Infect Dis. 2020;20(1):436.","journal-title":"BMC Infect Dis."},{"issue":"1","key":"8974_CR14","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1186\/s12902-019-0458-0","volume":"19","author":"H Falhammar","year":"2019","unstructured":"Falhammar H, Wallin G, Calissendorff J. Acute suppurative thyroiditis with thyroid abscess in adults: clinical presentation, treatment and outcomes. BMC Endocr Disord. 2019;19(1):130.","journal-title":"BMC Endocr Disord."},{"key":"8974_CR15","first-page":"51","volume":"26","author":"N Ghaemi","year":"2014","unstructured":"Ghaemi N, Sayedi J, Bagheri S. Acute suppurative thyroiditis with thyroid abscess: a case report and review of the literature. Iran J Otorhinolaryngol. 2014;26:51\u20135.","journal-title":"Iran J Otorhinolaryngol."},{"key":"8974_CR16","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.amjmed.2006.03.016","volume":"119","author":"K Lethert","year":"2006","unstructured":"Lethert K, Bowerman J, Pont A, Earle K, Garcia-Kennedy R. Methicillin-resistant Staphylococcus aureus suppurative thyroiditis with thyrotoxicosis. Am J Med. 2006;119:e1\u20132.","journal-title":"Am J Med."},{"issue":"4","key":"8974_CR17","doi-asserted-by":"publisher","first-page":"682","DOI":"10.2174\/1871530320666200621180515","volume":"21","author":"M Zangiabadian","year":"2021","unstructured":"Zangiabadian M, Mirsaeidi M, Pooyafar MH, Goudarzi M, Nasiri MJ. Associations of Yersinia Enterocolitica infection with autoimmune thyroid diseases: a systematic review and Meta-analysis. Endocr Metab Immune Disord Drug Targets. 2021;21(4):682\u20137.","journal-title":"Endocr Metab Immune Disord Drug Targets."}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-024-08974-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12879-024-08974-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-024-08974-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T12:02:23Z","timestamp":1704715343000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-024-08974-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,8]]},"references-count":17,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["8974"],"URL":"https:\/\/doi.org\/10.1186\/s12879-024-08974-1","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,8]]},"assertion":[{"value":"4 October 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 January 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The need for approval was waived off by the Institutional Review Board of Oita University Hospital. Written informed consent was obtained from the patient.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient to publish this case report and any accompanying images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"59"}}