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The purpose of this study was to determine the Bacteriological safety and antibiotic resistance patterns of\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      and Enterobacteriaceae isolated from street foods.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A laboratory-based cross-sectional study was used from December 2022 to February 2023 on street foods of Addis Ababa, Hawassa, Dire Dawa, and Jimma towns of Ethiopia. 525 street foods and 175 water samples were taken from 175 street food vending stalls. Proportional allocation to the total town population and stratified sampling techniques were used to select vending stalls. Samples were analyzed for the presence of bacteria following the standard microbiological methods used for the isolation, enumeration, and identification of bacteria. Pour plate technique was used to transfer the suspension to MacConkey agar, Mannitol Salt Agar, and Salmonella Shigella Agar. The antibiotic susceptibility test was performed using the Kirby-Bauer disk diffusion method. SPSS software was used to analyze the data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result<\/jats:title>\n                    <jats:p>\n                      Out of 525 food samples, 279 (53%) were contaminated by bacteria. From 175 water samples, 95 (54.3%) were contaminated with\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                      . From both samples in total, eleven bacterial species were isolated.\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      was the most frequently isolated species.\n                      <jats:italic>Shigella<\/jats:italic>\n                      ,\n                      <jats:italic>Klebsiella<\/jats:italic>\n                      , and\n                      <jats:italic>Salmonella group A<\/jats:italic>\n                      have statistically significant with the type of food. Erythromycin (54%), Streptomycin (17%), and Amoxicillin (14%) were the most resistant antibiotics. Least resistance was observed to Ciprofloxacin (5%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Street foods of the selected towns were highly contaminated with various antibiotic-resistant organisms. Hence, the relevant authorities ought to ensure the proper handling of street food by enforcing safety measures. Additionally, they should initiate a widespread awareness campaign promoting the prudent use of antibiotics among both street food vendors and the broader population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12879-024-09266-4","type":"journal-article","created":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T05:02:24Z","timestamp":1712034144000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Antibiotic resistance patterns of Staphylococcus aureus and Enterobacteriaceae isolated from street foods in selected towns of Ethiopia"],"prefix":"10.1186","volume":"24","author":[{"given":"Mathewos","family":"Moges","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernst Kristian","family":"Rodland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tesfaye","family":"Legesse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambelu","family":"Argaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,2]]},"reference":[{"issue":"11","key":"9266_CR1","doi-asserted-by":"publisher","first-page":"3049","DOI":"10.20546\/ijcmas.2018.711.350","volume":"7","author":"AAM Sabuj","year":"2018","unstructured":"Sabuj AAM, Haque ZF, Barua N, Islam MA, Saha S. 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