{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T13:35:41Z","timestamp":1789133741725,"version":"build-2803163510"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T00:00:00Z","timestamp":1721347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T00:00:00Z","timestamp":1721347200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100019448","name":"Zigong Science and Technology Program of China","doi-asserted-by":"publisher","award":["2023YLWS05"],"award-info":[{"award-number":["2023YLWS05"]}],"id":[{"id":"10.13039\/501100019448","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Special Project for Scientific and Technological Research of Sichuan Provincial Administration of Traditional Chinese Medicine","award":["2023MS494"],"award-info":[{"award-number":["2023MS494"]}]},{"name":"Research project of Zigong City Science & Technology and Intellectual Property Right Bureau","award":["2022ZCYGY05"],"award-info":[{"award-number":["2022ZCYGY05"]}]},{"name":"Sichuan Medical Association Scientific Research Project","award":["S21019"],"award-info":[{"award-number":["S21019"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>K.<\/jats:italic>\n                      pneumoniae liver abscess (KPLA) mostly involves the right lobe. We present a case of\n                      <jats:italic>K. pneumoniae<\/jats:italic>\n                      caudate liver abscess with invasive liver abscess syndrome (ILAS) was rarely identified.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>\n                      A 53-year-old man with elevated glycated hemoglobin with chills, rigors and a fever of five days. The patient presented with tachycardia and fever. Physical examination revealed tenderness over the right abdomen was elicited. In particular, the inflammatory markers were markedly elevated, and computerized tomography (CT) showed pulmonary abscess, pulmonary embolism and caudate liver abscess. The patient\u2019s sequential organ failure assessment (SOFA) score was 10 points.\n                      <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                      was isolated from sputum, urine and blood. With the suspicion of liver abscesses, ILAS and sepsis. The patient was successfully treated with antibiotics. He returned to close to his premorbid function.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:italic>K. pneumoniae<\/jats:italic>\n                      caudate liver abscess was rare. This is the first detailed report of\n                      <jats:italic>K. pneumoniae<\/jats:italic>\n                      caudate liver abscess with invasive liver abscess syndrome. Patients with cryptogenic\n                      <jats:italic>K. pneumoniae<\/jats:italic>\n                      liver abscess are advised to undergo an examination of intestinal barrier function. The study indicates that in patients with\n                      <jats:italic>K. pneumoniae<\/jats:italic>\n                      liver abscess, a caudate liver abscess size of \u2264\u20099.86\u00a0cm\u00b2 may be characteristic of those suitable for conservative treatment of invasive liver abscess syndrome.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12879-024-09569-6","type":"journal-article","created":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T06:01:44Z","timestamp":1721368904000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Liver abscess in the caudate lobe caused by Klebsiella pneumoniae: a rare case report and literature review"],"prefix":"10.1186","volume":"24","author":[{"given":"Lingxia","family":"Cheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongzao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,19]]},"reference":[{"key":"9569_CR1","doi-asserted-by":"crossref","unstructured":"He S, Yu J, Wang H, Chen X, He Z, Chen Y. Percutaneous fine-needle aspiration for pyogenic liver abscess (3\u20136\u00a0cm): a two-center retrospective study. BMC Infect Dis. 2020;20(1).","DOI":"10.1186\/s12879-020-05239-5"},{"issue":"2","key":"9569_CR2","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1002\/jhbp.174","volume":"22","author":"JZ Lo","year":"2015","unstructured":"Lo JZ, Leow JJ, Ng PL, Lee HQ, Mohd Noor NA, Low JK, Junnarkar SP, Woon WW. Predictors of therapy failure in a series of 741 adult pyogenic liver abscesses. J Hepato-Biliary-Pancreat Sci. 2015;22(2):156\u201365.","journal-title":"J Hepato-Biliary-Pancreat Sci"},{"issue":"3","key":"9569_CR3","doi-asserted-by":"publisher","first-page":"683","DOI":"10.4269\/ajtmh.16-0228","volume":"95","author":"K Poovorawan","year":"2016","unstructured":"Poovorawan K, Pan-Ngum W, Soonthornworasiri N, Kulrat C, Kittitrakul C, Wilairatana P, Treeprasertsuk S, Kitsahawong B, Phaosawasdi K. Burden of liver abscess and survival risk score in Thailand: a Population-based study. Am J Trop Med Hyg. 2016;95(3):683\u20138.","journal-title":"Am J Trop Med Hyg"},{"issue":"4","key":"9569_CR4","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1111\/liv.14760","volume":"41","author":"D Yin","year":"2021","unstructured":"Yin D, Ji C, Zhang S, Wang J, Lu Z, Song X, Jiang H, Lau WY, Liu L. Clinical characteristics and management of 1572 patients with pyogenic liver abscess: a 12-year retrospective study. Liver Int. 2021;41(4):810\u20138.","journal-title":"Liver Int"},{"issue":"5","key":"9569_CR5","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1086\/590932","volume":"47","author":"SS Lee","year":"2008","unstructured":"Lee SS, Chen YS, Tsai HC, Wann SR, Lin HH, Huang CK, Liu YC. Predictors of septic metastatic infection and mortality among patients with Klebsiella pneumoniae liver abscess. Clin Infect Dis. 2008;47(5):642\u201350.","journal-title":"Clin Infect Dis"},{"issue":"11","key":"9569_CR6","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1016\/S1473-3099(12)70205-0","volume":"12","author":"LK Siu","year":"2012","unstructured":"Siu LK, Yeh KM, Lin JC, Fung CP, Chang FY. Klebsiella pneumoniae liver abscess: a new invasive syndrome. Lancet Infect Dis. 2012;12(11):881\u20137.","journal-title":"Lancet Infect Dis"},{"issue":"1","key":"9569_CR7","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1186\/s12879-021-06325-y","volume":"21","author":"S Li","year":"2021","unstructured":"Li S, Yu S, Peng M, Qin J, Xu C, Qian J, He M, Zhou P. Clinical features and development of Sepsis in Klebsiella pneumoniae infected liver abscess patients: a retrospective analysis of 135 cases. BMC Infect Dis. 2021;21(1):597.","journal-title":"BMC Infect Dis"},{"issue":"5","key":"9569_CR8","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1080\/00365521.2017.1288757","volume":"52","author":"H Cho","year":"2017","unstructured":"Cho H, Lee ES, Lee YS, Kim YJ, Sohn CH, Ahn S, Seo DW, Lee JH, Kim WY, Lim KS. Predictors of septic shock in initially stable patients with pyogenic liver abscess. Scand J Gastroenterol. 2017;52(5):589\u201394.","journal-title":"Scand J Gastroenterol"},{"issue":"5","key":"9569_CR9","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1177\/0284185113477400","volume":"54","author":"SU Shin","year":"2013","unstructured":"Shin SU, Park CM, Lee Y, Kim EC, Kim SJ, Goo JM. Clinical and radiological features of invasive Klebsiella pneumoniae liver abscess syndrome. Acta Radiol. 2013;54(5):557\u201363.","journal-title":"Acta Radiol"},{"key":"9569_CR10","doi-asserted-by":"crossref","unstructured":"Lee JJ, Hong SB, Lee NK, Park YJ, Kim SH, Park SW, Byon I, Kim S. Characteristics of computed tomography for identifying patients at high risk of endogenous endophthalmitis due to klebsiella pneumoniae-related pyogenic liver abscess. J Clin Med. 2022;11(15).","DOI":"10.3390\/jcm11154376"},{"key":"9569_CR11","doi-asserted-by":"publisher","first-page":"24","DOI":"10.3389\/fcimb.2017.00024","volume":"7","author":"Y Guo","year":"2017","unstructured":"Guo Y, Wang S, Zhan L, Jin Y, Duan J, Hao Z, Lv J, Qi X, Chen L, Kreiswirth BN, et al. Microbiological and clinical characteristics of Hypermucoviscous Klebsiella pneumoniae isolates associated with invasive infections in China. Front Cell Infect Microbiol. 2017;7:24.","journal-title":"Front Cell Infect Microbiol"},{"issue":"2","key":"9569_CR12","doi-asserted-by":"publisher","first-page":"221","DOI":"10.3201\/eid2402.170957","volume":"24","author":"B Rossi","year":"2018","unstructured":"Rossi B, Gasperini ML, Leflon-Guibout V, Gioanni A, de Lastours V, Rossi G, Dokmak S, Ronot M, Roux O, Nicolas-Chanoine M-H, et al. HypervirulentKlebsiella pneumoniaein cryptogenic liver abscesses, Paris, France. Emerg Infect Dis. 2018;24(2):221\u20139.","journal-title":"Emerg Infect Dis"},{"issue":"11","key":"9569_CR13","doi-asserted-by":"publisher","first-page":"1654","DOI":"10.1086\/425616","volume":"39","author":"J Rahimian","year":"2004","unstructured":"Rahimian J, Wilson T, Oram V, Holzman RS. Pyogenic liver abscess: recent trends in etiology and mortality. Clin Infect dis. 2004;39(11):1654\u20139.","journal-title":"Clin Infect dis"},{"issue":"5","key":"9569_CR14","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/S1473-3099(13)70068-9","volume":"13","author":"DX Shen","year":"2013","unstructured":"Shen DX, Wang J, Li DD. Klebsiella pneumoniae liver abscesses. Lancet Infect dis. 2013;13(5):390\u20131.","journal-title":"Lancet Infect dis"},{"key":"9569_CR15","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1186\/s12879-015-0899-7","volume":"15","author":"TT Qu","year":"2015","unstructured":"Qu TT, Zhou JC, Jiang Y, Shi KR, Li B, Shen P, Wei ZQ, Yu YS. Clinical and microbiological characteristics of Klebsiella pneumoniae liver abscess in East China. BMC Infect Dis. 2015;15:161.","journal-title":"BMC Infect Dis"},{"issue":"1","key":"9569_CR16","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1186\/s13256-018-1924-4","volume":"12","author":"PNS Premathilake","year":"2018","unstructured":"Premathilake PNS, Kularatne WKS, Jayathilake JPK, Senadhira SDN. Klebsiella pneumoniae liver abscess: a case report. J Med Case Rep. 2018;12(1):367.","journal-title":"J Med Case Rep"},{"key":"9569_CR17","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1186\/s13756-019-0615-2","volume":"8","author":"S Zhang","year":"2019","unstructured":"Zhang S, Zhang X, Wu Q, Zheng X, Dong G, Fang R, Zhang Y, Cao J, Zhou T. Clinical, microbiological, and molecular epidemiological characteristics of Klebsiella pneumoniae-induced pyogenic liver abscess in southeastern China. Antimicrob Resist Infect Control. 2019;8:166.","journal-title":"Antimicrob Resist Infect Control"},{"issue":"1","key":"9569_CR18","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1186\/s12879-020-05239-5","volume":"20","author":"S He","year":"2020","unstructured":"He S, Yu J, Wang H, Chen X, He Z, Chen Y. Percutaneous fine-needle aspiration for pyogenic liver abscess (3\u20136\u00a0cm): a two-center retrospective study. BMC Infect Dis. 2020;20(1):516.","journal-title":"BMC Infect Dis"},{"issue":"1","key":"9569_CR19","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1186\/s12879-020-05142-z","volume":"20","author":"Y Ren","year":"2020","unstructured":"Ren Y, Wang H, Chang Z, Liu Z. Clinical and computed tomography features of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae liver abscess. BMC Infect Dis. 2020;20(1):416.","journal-title":"BMC Infect Dis"},{"issue":"2","key":"9569_CR20","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1177\/0897190019882867","volume":"34","author":"ME Bradley","year":"2021","unstructured":"Bradley ME, Scoular SK. Metastatic Klebsiella pneumoniae invasive liver abscess syndrome in Denver, Colorado. J Pharm Pract. 2021;34(2):332\u20136.","journal-title":"J Pharm Pract"},{"issue":"1","key":"9569_CR21","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s00423-023-02837-0","volume":"408","author":"I Justo","year":"2023","unstructured":"Justo I, Vega V, Marcacuzco A, Caso \u00d3, Garc\u00eda-Conde M, Manrique A, Calvo J, Garc\u00eda-Sesma \u00c1, San Juan R, Fern\u00e1ndez-Ruiz M, et al. Risk factors indicating the need for surgical therapy in patients with pyogenic liver abscesses. Langenbecks Archives Surg. 2023;408(1):97.","journal-title":"Langenbecks Archives Surg"},{"issue":"12","key":"9569_CR22","doi-asserted-by":"publisher","first-page":"861","DOI":"10.4103\/ijccm.IJCCM_279_17","volume":"21","author":"D Khurana","year":"2017","unstructured":"Khurana D, Deoke SA. Thrombocytopenia in critically ill patients: clinical and laboratorial behavior and its correlation with short-term outcome during hospitalization. Indian J Crit Care Med. 2017;21(12):861\u20134.","journal-title":"Indian J Crit Care Med"},{"key":"9569_CR23","doi-asserted-by":"publisher","first-page":"1669","DOI":"10.2147\/IDR.S174913","volume":"11","author":"CH Lee","year":"2018","unstructured":"Lee CH, Chuah SK, Tai WC, Chen IL. Platelet reactivity in diabetic patients with invasive Klebsiella pneumoniae liver abscess syndrome. Infect Drug Resist. 2018;11:1669\u201376.","journal-title":"Infect Drug Resist"},{"issue":"12","key":"9569_CR24","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1016\/S1726-4901(09)70001-2","volume":"71","author":"JC Lin","year":"2008","unstructured":"Lin JC, Chang FY. Pyogenic liver abscess associated with septic pulmonary embolism. J Chin Med Association. 2008;71(12):603\u20134.","journal-title":"J Chin Med Association"},{"issue":"38","key":"9569_CR25","doi-asserted-by":"publisher","first-page":"e12326","DOI":"10.1097\/MD.0000000000012326","volume":"97","author":"WJ Wang","year":"2018","unstructured":"Wang WJ, Tao Z, Wu HL. Etiology and clinical manifestations of bacterial liver abscess: a study of 102 cases. Med (Baltim). 2018;97(38):e12326.","journal-title":"Med (Baltim)"},{"issue":"20","key":"9569_CR26","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1024\/1661-8157\/a002155","volume":"104","author":"E Biskup","year":"2015","unstructured":"Biskup E, Yang XY. Pyogenic hepatic abscess\u2013less is more. A review for General internists. Praxis (Bern 1994). 2015;104(20):1091\u20135.","journal-title":"Praxis (Bern 1994)"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-024-09569-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12879-024-09569-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-024-09569-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T06:02:47Z","timestamp":1721368967000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-024-09569-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,19]]},"references-count":26,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["9569"],"URL":"https:\/\/doi.org\/10.1186\/s12879-024-09569-6","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-4138146\/v1","asserted-by":"object"}]},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,19]]},"assertion":[{"value":"20 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"N\/A.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Patient provided informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The patient gave written, informed consent for the publication of any personal or medical information in this case report. Data from the clinical workout were used in this case report, which was conducted and presented in an anonymous manner.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"708"}}