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The aim of this study is to investigate the association between current and past <jats:italic>H. pylori<\/jats:italic> infections and elevated levels of microalbuminuria in type 2 diabetic patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Two hundred patients with type 2 diabetes mellitus were tested for the presence of <jats:italic>H. pylori<\/jats:italic> infection. They were divided into three groups: 52 had a current <jats:italic>H. pylori<\/jats:italic> infection, 38 had a past <jats:italic>H. pylori<\/jats:italic> infection, and 110 had no <jats:italic>H. pylori<\/jats:italic> infection. All study participants underwent assessments of plasma glucose levels, glycated hemoglobin (HbA1c), albuminuria levels, inflammatory markers such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), as well as other relevant investigations.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The prevalence of <jats:italic>H. pylori<\/jats:italic> infection (current and past) was detected in 90 out of 200 diabetic patients (45%). There was no statistically significant difference between the three groups in terms of age, diabetes duration, family history of DM, family history of hypertension, residence, or dyspeptic symptoms, indicating that current or past infection with <jats:italic>H. pylori<\/jats:italic> has no association with these variables. The current <jats:italic>H. pylori<\/jats:italic> infection group showed the highest levels of inflammatory markers, ESR and CRP, which were significantly different from those in the non-infected group (<jats:italic>p<\/jats:italic>\u2009=\u20090.013 and <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, respectively). The median (IQR) of albuminuria levels in the current <jats:italic>H. pylori<\/jats:italic> infection group, the past <jats:italic>H. pylori<\/jats:italic> infection group, and the non-infected group were 125 (4.8\u2013290), 7.6 (2.4\u2013271), and 5.1 (1.2\u2013173), respectively. The current <jats:italic>H. pylori<\/jats:italic> infection group showed the highest albuminuria level, which was significantly different from that of the non-infected group (<jats:italic>p<\/jats:italic>\u2009=\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>There might be an association between microalbuminuria levels, general inflammatory markers (ESR and CRP), and current H. pylori infection in type 2 diabetic patients.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12879-024-09918-5","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T17:01:51Z","timestamp":1727802111000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A comparative study between current and past Helicobacter pylori infection in terms of microalbuminuria in patients with type 2 diabetes"],"prefix":"10.1186","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6434-9071","authenticated-orcid":false,"given":"Hosam M.","family":"Ahmad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hussein S.","family":"Al-Fishawy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inass","family":"Shaltout","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emad A. 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