{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T16:06:25Z","timestamp":1773849985950,"version":"3.50.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T00:00:00Z","timestamp":1727395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T00:00:00Z","timestamp":1727395200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"DOI":"10.1186\/s12879-024-09981-y","type":"journal-article","created":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T09:02:35Z","timestamp":1727427755000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Recurrent pulmonary nocardiosis due to Nocardia Otitidiscaviarum in a patient with isolated CD4 lymphocytopenia: a case report"],"prefix":"10.1186","volume":"24","author":[{"given":"Tejasvi","family":"Kanagiri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9524-5278","authenticated-orcid":false,"given":"Durga Shankar","family":"Meena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naresh Kumar","family":"Midha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarika","family":"Kombade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taruna","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,9,27]]},"reference":[{"issue":"18","key":"9981_CR1","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.1056\/NEJMoa2202348","volume":"388","author":"A Lisco","year":"2023","unstructured":"Lisco A, Ortega-Villa AM, Mystakelis H, Anderson MV, Mateja A, Laidlaw E, et al. Reappraisal of idiopathic CD4 Lymphocytopenia at 30 years. N Engl J Med. 2023;388(18):1680\u201391. https:\/\/doi.org\/10.1056\/NEJMoa2202348.","journal-title":"N Engl J Med"},{"issue":"3","key":"9981_CR2","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1111\/j.1574-695X.2008.00490.x","volume":"54","author":"L Luo","year":"2008","unstructured":"Luo L, Li T. Idiopathic CD4 lymphocytopenia and opportunistic infection\u2013an update. FEMS Immunol Med Microbiol. 2008;54(3):283\u20139. https:\/\/doi.org\/10.1111\/j.1574-695X.2008.00490.x.","journal-title":"FEMS Immunol Med Microbiol"},{"issue":"1","key":"9981_CR3","doi-asserted-by":"publisher","first-page":"14272","DOI":"10.1038\/s41598-020-71214-4","volume":"10","author":"I Margalit","year":"2020","unstructured":"Margalit I, Goldberg E, Ben Ari Y, Ben-Zvi H, Shostak Y, Krause I, et al. Clinical correlates of nocardiosis. Sci Rep. 2020;10(1):14272. https:\/\/doi.org\/10.1038\/s41598-020-71214-4.","journal-title":"Sci Rep"},{"issue":"6","key":"9981_CR4","doi-asserted-by":"publisher","first-page":"e13753","DOI":"10.1111\/tid.13753","volume":"23","author":"ZA Yetmar","year":"2021","unstructured":"Yetmar ZA, Wilson JW, Beam E. Recurrent nocardiosis in solid organ transplant recipients: an evaluation of secondary prophylaxis. Transpl Infect Dis. 2021;23(6):e13753. https:\/\/doi.org\/10.1111\/tid.13753.","journal-title":"Transpl Infect Dis"},{"issue":"9","key":"9981_CR5","first-page":"930","volume":"38","author":"F G\u00f6ktay","year":"2011","unstructured":"G\u00f6ktay F, Mansur AT, Er\u015fahin M, Adaleti R, G\u00fcne\u015f P. Idiopathic CD4\u2009+\u2009T lymphocytopenia with epidermodysplasia verruciformis-like skin eruption, Nocardia farcinica brain abscesses and pulmonary tuberculosis: a case report with fatal outcome. J Dermatol. 2011;38(9):930\u20133.","journal-title":"J Dermatol"},{"issue":"2","key":"9981_CR6","doi-asserted-by":"publisher","first-page":"e00283","DOI":"10.1002\/rcr2.283","volume":"6","author":"V Jayaschandran","year":"2017","unstructured":"Jayaschandran V, Gjorgova-Gjeorgjievski S, Siddique H. Pulmonary nocardiosis in a patient with idiopathic CD4 T-lymphocytopenia. Respirol Case Rep. 2017;6(2):e00283. https:\/\/doi.org\/10.1002\/rcr2.283.","journal-title":"Respirol Case Rep"},{"issue":"1","key":"9981_CR7","first-page":"455","volume":"11","author":"K Tajima","year":"2018","unstructured":"Tajima K, Terada T, Okuyama S, Akaneya D, Hori R, Abe S, et al. Nocardia otitidiscaviarum meningitis in a diffuse large B-cell lymphoma patient with CD4-positive lymphocytopenia and persistent oligoclonal CD8-positive lymphocytes in the peripheral blood. Int J Clin Exp Pathol. 2018;11(1):455\u201361.","journal-title":"Int J Clin Exp Pathol"},{"key":"9981_CR8","doi-asserted-by":"publisher","first-page":"79","DOI":"10.2147\/ITT.S214139","volume":"9","author":"S Vijayakumar","year":"2020","unstructured":"Vijayakumar S, Viswanathan S, Aghoram R. Idiopathic CD4 Lymphocytopenia: current insights. Immunotargets Ther. 2020;9:79\u201393. https:\/\/doi.org\/10.2147\/ITT.S214139.","journal-title":"Immunotargets Ther"},{"issue":"6","key":"9981_CR9","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1159\/000508717","volume":"29","author":"SD Duggal","year":"2020","unstructured":"Duggal SD, Chugh TD. Nocardiosis: a neglected disease. Med Princ Pract. 2020;29(6):514\u201323. https:\/\/doi.org\/10.1159\/000508717.","journal-title":"Med Princ Pract"},{"issue":"4","key":"9981_CR10","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1159\/000525509","volume":"31","author":"DS Meena","year":"2022","unstructured":"Meena DS, Kumar D, Bohra GK, Midha N, Garg MK. Clinical characteristics and treatment outcome of Central Nervous System Nocardiosis: a systematic review of reported cases. Med Princ Pract. 2022;31(4):333\u201341. https:\/\/doi.org\/10.1159\/000525509.","journal-title":"Med Princ Pract"},{"issue":"3","key":"9981_CR11","doi-asserted-by":"publisher","first-page":"e35","DOI":"10.1093\/jpids\/pit038","volume":"3","author":"JM Wessler","year":"2014","unstructured":"Wessler JM, Adams DJ, Kunz AN, Babcock JG, Hartman KR. Recurrent Nocardia Sepsis in a patient with Sickle Cell Anemia receiving continuous deferoxamine. J Pediatr Infect Dis Soc. 2014;3(3):e35\u20137. https:\/\/doi.org\/10.1093\/jpids\/pit038.","journal-title":"J Pediatr Infect Dis Soc"},{"issue":"8","key":"9981_CR12","doi-asserted-by":"publisher","first-page":"e17250","DOI":"10.7759\/cureus.17250","volume":"13","author":"P Yadav","year":"2021","unstructured":"Yadav P, Kumar D, Meena DS, Bohra GK, Jain V, Garg P, et al. Clinical features, radiological findings, and treatment outcomes in patients with pulmonary nocardiosis: a retrospective analysis. Cureus. 2021;13(8):e17250. https:\/\/doi.org\/10.7759\/cureus.17250.","journal-title":"Cureus"},{"key":"9981_CR13","doi-asserted-by":"publisher","unstructured":"Adjamian N, Kikam A, Wessell KR, Casselman J, Toller-Artis E, Olasokan O, et al. Nocardia Brain Abscess and CD4(+) Lymphocytopenia in a previously healthy individual. Case Rep Immunol. 2015;374956. https:\/\/doi.org\/10.1155\/2015\/374956.","DOI":"10.1155\/2015\/374956"},{"issue":"8","key":"9981_CR14","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1007\/s10875-020-00866-8","volume":"40","author":"E Lafont","year":"2020","unstructured":"Lafont E, Marciano BE, Mahlaoui N, Neven B, Bustamante J, Rodriguez-Nava V, et al. Nocardiosis Associated with primary immunodeficiencies (Nocar-DIP): an International Retrospective Study and Literature Review. J Clin Immunol. 2020;40(8):1144\u201355. https:\/\/doi.org\/10.1007\/s10875-020-00866-8.","journal-title":"J Clin Immunol"},{"issue":"1","key":"9981_CR15","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s12941-022-00511-9","volume":"21","author":"M Barry","year":"2022","unstructured":"Barry M, AlShehri S, Alguhani A, Barry M, Alhijji A, Binkhamis K, et al. A fatal case of disseminated nocardiosis due to Nocardia otitidiscaviarum resistant to trimethoprim-sulfamethoxazole: case report and literature review. Ann Clin Microbiol Antimicrob. 2022;21(1):17. https:\/\/doi.org\/10.1186\/s12941-022-00511-9.","journal-title":"Ann Clin Microbiol Antimicrob"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-024-09981-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12879-024-09981-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-024-09981-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T21:02:04Z","timestamp":1727470924000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-024-09981-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,27]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["9981"],"URL":"https:\/\/doi.org\/10.1186\/s12879-024-09981-y","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,27]]},"assertion":[{"value":"31 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent has been taken from the patient.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The patient has given written consent for his personal and clinical details. The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given their consent for their images and other clinical information to be reported in the journal. The patient understand that her name and initials will not be published and due efforts will be made to conceal her identity.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1033"}}