{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T23:31:43Z","timestamp":1781652703448,"version":"3.54.5"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T00:00:00Z","timestamp":1732233600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T00:00:00Z","timestamp":1732233600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"DOI":"10.1186\/s12879-024-10236-z","type":"journal-article","created":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T10:54:30Z","timestamp":1732272870000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Fecal carriage of extended-spectrum \u03b2-lactamase-producing, and carbapenem-resistant gram-negative bacteria among hemodialysis patients in a palestinian tertiary care hospital"],"prefix":"10.1186","volume":"24","author":[{"given":"Abdullah","family":"Janem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawod","family":"Jawabreh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqoot","family":"Anabseh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Jawabreh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaher","family":"Nazzal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adham Abu","family":"Taha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Qadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,22]]},"reference":[{"key":"10236_CR1","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1086\/675592","volume":"35","author":"E Lautenbach","year":"2014","unstructured":"Lautenbach E, Perencevich EN. Addressing the emergence and impact of multidrug-resistant gram-negative organisms: a critical focus for the next decade. Infect Control Hosp Epidemiol. 2014;35:333\u20135.","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10236_CR2","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1002\/phar.1636","volume":"35","author":"KS Kaye","year":"2015","unstructured":"Kaye KS, Pogue JM. Infections caused by resistant gram-negative Bacteria: Epidemiology and Management. Pharmacotherapy. 2015;35:949\u201362.","journal-title":"Pharmacotherapy"},{"key":"10236_CR3","doi-asserted-by":"publisher","first-page":"3022","DOI":"10.1038\/s41598-024-53596-x","volume":"14","author":"BM Aiesh","year":"2024","unstructured":"Aiesh BM, et al. Epidemiology and clinical characteristics of patients with healthcare-acquired multidrug-resistant Gram-negative bacilli: a retrospective study from a tertiary care hospital. Sci Rep. 2024;14:3022.","journal-title":"Sci Rep"},{"key":"10236_CR4","doi-asserted-by":"crossref","unstructured":"Qadi M, Alhato S, Khayyat R, Elmanama AA. Colistin Resistance among Enterobacteriaceae Isolated from Clinical Samples in Gaza Strip. Canadian Journal of Infectious Diseases and Medical Microbiology 2021, 6634684.","DOI":"10.1155\/2021\/6634684"},{"key":"10236_CR5","unstructured":"CDC. The biggest antibiotic-resistant threats in the U.S. Centers Disease Control Prev 2022.https:\/\/www.cdc.gov\/drugresistance\/biggest-threats.html."},{"key":"10236_CR6","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.mib.2019.10.008","volume":"51","author":"MI Hutchings","year":"2019","unstructured":"Hutchings MI, Truman AW, Wilkinson B. Antibiotics: past, present and future. Curr Opin Microbiol. 2019;51:72\u201380.","journal-title":"Curr Opin Microbiol"},{"issue":"Suppl 1","key":"10236_CR7","doi-asserted-by":"publisher","first-page":"S9","DOI":"10.1016\/j.cmi.2016.01.001","volume":"22","author":"F-P Hu","year":"2016","unstructured":"Hu F-P, et al. Resistance trends among clinical isolates in China reported from CHINET surveillance of bacterial resistance, 2005\u20132014. Clin Microbiol Infect. 2016;22(Suppl 1):S9\u201314.","journal-title":"Clin Microbiol Infect"},{"key":"10236_CR8","doi-asserted-by":"crossref","unstructured":"Qadi M et al. Colistin and Antimicrobial Resistance among Gram-negative Bacteria isolated from Poultry in West Bank, Palestine. Palestinian Med Pharm J 9, (2024).","DOI":"10.59049\/2790-0231.1129"},{"key":"10236_CR9","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.2215\/CJN.00950208","volume":"3","author":"S Kato","year":"2008","unstructured":"Kato S, et al. Aspects of immune dysfunction in end-stage renal disease. Clin J Am Soc Nephrol. 2008;3:1526\u201333.","journal-title":"Clin J Am Soc Nephrol"},{"key":"10236_CR10","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1586\/eri.10.47","volume":"8","author":"AJ Kallen","year":"2010","unstructured":"Kallen AJ, Arduino MJ, Patel PR. Preventing infections in patients undergoing hemodialysis. Expert Rev Anti Infect Ther. 2010;8:643\u201355.","journal-title":"Expert Rev Anti Infect Ther"},{"key":"10236_CR11","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1038\/ki.2012.345","volume":"83","author":"ND Vaziri","year":"2013","unstructured":"Vaziri ND, et al. Chronic kidney disease alters intestinal microbial flora. Kidney Int. 2013;83:308\u201315.","journal-title":"Kidney Int"},{"key":"10236_CR12","doi-asserted-by":"crossref","unstructured":"Johansen KL, et al. Epidemiology of Kidney Disease in the United States. Am J Kidney Dis. 2021;77:A7\u20138. US Renal Data System 2020 Annual Data Report:.","DOI":"10.1053\/j.ajkd.2021.01.002"},{"key":"10236_CR13","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1093\/ndt\/gfv007","volume":"30","author":"JL Vogelzang","year":"2015","unstructured":"Vogelzang JL, et al. Mortality from infections and malignancies in patients treated with renal replacement therapy: data from the ERA-EDTA registry. Nephrol Dial Transpl. 2015;30:1028\u201337.","journal-title":"Nephrol Dial Transpl"},{"key":"10236_CR14","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.jinf.2012.06.005","volume":"65","author":"D Bleumin","year":"2012","unstructured":"Bleumin D, et al. Carbapenem-resistant Klebsiella pneumoniae is associated with poor outcome in hemodialysis patients. J Infect. 2012;65:318\u201325.","journal-title":"J Infect"},{"key":"10236_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3109\/1040841X.2013.875515","volume":"42","author":"LM Biehl","year":"2016","unstructured":"Biehl LM, Schmidt-Hieber M, Liss B, Cornely OA, Vehreschild MJGT. Colonization and infection with extended spectrum beta-lactamase producing Enterobacteriaceae in high-risk patients - review of the literature from a clinical perspective. Crit Rev Microbiol. 2016;42:1\u201316.","journal-title":"Crit Rev Microbiol"},{"key":"10236_CR16","doi-asserted-by":"publisher","first-page":"45","DOI":"10.5694\/j.1326-5377.2009.tb02266.x","volume":"190","author":"JT Denholm","year":"2009","unstructured":"Denholm JT, Huysmans M, Spelman D. Community acquisition of ESBL-producing Escherichia coli: a growing concern. Med J Aust. 2009;190:45\u20136.","journal-title":"Med J Aust"},{"key":"10236_CR17","doi-asserted-by":"publisher","first-page":"e61","DOI":"10.1016\/j.ajic.2014.01.024","volume":"42","author":"Z Zhao","year":"2014","unstructured":"Zhao Z, et al. Fecal carriage of carbapenem-resistant Enterobacteriaceae in a Chinese university hospital. Am J Infect Control. 2014;42:e61\u201364.","journal-title":"Am J Infect Control"},{"key":"10236_CR18","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.jhin.2020.10.026","volume":"107","author":"L Salazar-Ospina","year":"2021","unstructured":"Salazar-Ospina L, Vanegas JM, Jim\u00e9nez JN. High intermittent colonization by diverse clones of \u03b2-lactam-resistant Gram-negative bacilli suggests an excessive antibiotic use and different sources of transmission in haemodialysis patients. J Hosp Infect. 2021;107:76\u201386.","journal-title":"J Hosp Infect"},{"key":"10236_CR19","doi-asserted-by":"crossref","unstructured":"Hosseinzadeh-sohi N, Najar-Peerayeh S, Bakhshi B. Intestinal carriage of extended-spectrum \u03b2-lactamase and carbapenemase-producing Enterobacteriaceae in Hemodialysis patients. Jundishapur J Microbiol 15, (2022).","DOI":"10.5812\/jjm-118946"},{"key":"10236_CR20","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1086\/590661","volume":"29","author":"D Calfee","year":"2008","unstructured":"Calfee D, Jenkins SG. Use of active surveillance cultures to detect asymptomatic colonization with carbapenem-resistant Klebsiella pneumoniae in intensive care unit patients. Infect Control Hosp Epidemiol. 2008;29:966\u20138.","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10236_CR21","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1016\/j.ajic.2015.12.005","volume":"44","author":"J Tischendorf","year":"2016","unstructured":"Tischendorf J, de Avila RA, Safdar N. Risk of infection following colonization with carbapenem-resistant enterobactericeae: a systematic review. Am J Infect Control. 2016;44:539\u201343.","journal-title":"Am J Infect Control"},{"key":"10236_CR22","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.cmi.2020.10.016","volume":"27","author":"ZR Palacios-Baena","year":"2021","unstructured":"Palacios-Baena ZR, et al. Risk factors for carbapenem-resistant Gram-negative bacterial infections: a systematic review. Clin Microbiol Infect. 2021;27:228\u201335.","journal-title":"Clin Microbiol Infect"},{"key":"10236_CR23","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s12882-023-03064-x","volume":"24","author":"A Taher","year":"2023","unstructured":"Taher A, et al. Growing a peritoneal dialysis program in Palestine from zero to 178 patients in 5 years: a single-center experience. BMC Nephrol. 2023;24:21.","journal-title":"BMC Nephrol"},{"key":"10236_CR24","unstructured":"Kumar S, Vyas A. Utilization of MacConkey-Meropenem screening Agar for the detection of Carbapenem Resistanant Enterobacteriaceae in a tertiary care hospital. in (2018)."},{"key":"10236_CR25","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1111\/j.1469-0691.2006.01667.x","volume":"13","author":"G Wilson","year":"2007","unstructured":"Wilson G, McCabe D. The use of antibiotic-containing agars for the isolation of extended-spectrum beta-lactamase-producing organisms in intensive care units. Clin Microbiol Infect. 2007;13:451\u20133.","journal-title":"Clin Microbiol Infect"},{"key":"10236_CR26","doi-asserted-by":"crossref","unstructured":"Odeh Z, Abatli S, Qadi M, Radiology Department. A Potential Source of Multidrug-Resistant Microorganisms: A Cross-Sectional Study at Tertiary Hospital, Palestine. Can J Infect Dis Med Microbiol 2023, 4441338.","DOI":"10.1155\/2023\/4441338"},{"key":"10236_CR27","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1017\/ice.2017.178","volume":"38","author":"W-P Tseng","year":"2017","unstructured":"Tseng W-P, et al. Predicting Multidrug-Resistant Gram-negative bacterial colonization and Associated Infection on Hospital Admission. Infect Control Hosp Epidemiol. 2017;38:1216\u201325.","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10236_CR28","doi-asserted-by":"publisher","first-page":"e74323","DOI":"10.1371\/journal.pone.0074323","volume":"8","author":"R Leistner","year":"2013","unstructured":"Leistner R, et al. Risk factors Associated with the community-acquired colonization of extended-spectrum beta-lactamase (ESBL) positive Escherichia Coli. An exploratory case-control study. PLoS ONE. 2013;8:e74323.","journal-title":"PLoS ONE"},{"key":"10236_CR29","doi-asserted-by":"publisher","first-page":"e287","DOI":"10.1093\/pubmed\/fdz095","volume":"42","author":"S Garry","year":"2020","unstructured":"Garry S, Checchi F. Armed conflict and public health: into the 21st century. J Public Health (Oxf). 2020;42:e287\u201398.","journal-title":"J Public Health (Oxf)"},{"key":"10236_CR30","unstructured":"Kattan R et al. Emergence of Klebsiella pneumoniae carbapenemase (blaKPC-2) in members of the enterobacteriaceae family in Palestine. Int Arabic J Antimicrob Agents 2, 2012."},{"key":"10236_CR31","doi-asserted-by":"publisher","first-page":"S28","DOI":"10.1093\/infdis\/jiw282","volume":"215","author":"LK Logan","year":"2017","unstructured":"Logan LK, Weinstein RA. The epidemiology of Carbapenem-Resistant Enterobacteriaceae: the impact and evolution of a global menace. J Infect Dis. 2017;215:S28\u201336.","journal-title":"J Infect Dis"},{"key":"10236_CR32","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/s11908-015-0510-9","volume":"18","author":"K Chiotos","year":"2016","unstructured":"Chiotos K, Han JH, Tamma PD. Carbapenem-Resistant Enterobacteriaceae infections in Children. Curr Infect Dis Rep. 2016;18:2.","journal-title":"Curr Infect Dis Rep"},{"key":"10236_CR33","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1111\/1469-0691.12747","volume":"20","author":"M Giannella","year":"2014","unstructured":"Giannella M, et al. Risk factors for carbapenem-resistant Klebsiella pneumoniae bloodstream infection among rectal carriers: a prospective observational multicentre study. Clin Microbiol Infect. 2014;20:1357\u201362.","journal-title":"Clin Microbiol Infect"},{"key":"10236_CR34","doi-asserted-by":"publisher","first-page":"752","DOI":"10.2215\/CJN.04651107","volume":"3","author":"A Pop-Vicas","year":"2008","unstructured":"Pop-Vicas A, Strom J, Stanley K, D\u2019Agata EM. C. Multidrug-resistant gram-negative bacteria among patients who require chronic hemodialysis. Clin J Am Soc Nephrol. 2008;3:752\u20138.","journal-title":"Clin J Am Soc Nephrol"},{"key":"10236_CR35","doi-asserted-by":"publisher","first-page":"680","DOI":"10.3390\/antibiotics10060680","volume":"10","author":"\u00c1 Rodr\u00edguez-Villodres","year":"2021","unstructured":"Rodr\u00edguez-Villodres \u00c1, et al. Prevalence and risk factors for Multidrug-resistant organisms colonization in Long-Term Care facilities around the World: a review. Antibiot (Basel). 2021;10:680.","journal-title":"Antibiot (Basel)"},{"key":"10236_CR36","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1016\/j.jhin.2008.02.003","volume":"68","author":"CT Moor","year":"2008","unstructured":"Moor CT, et al. Extended-spectrum beta-lactamase (ESBL)-producing enterobacteria: factors associated with infection in the community setting, Auckland, New Zealand. J Hosp Infect. 2008;68:355\u201362.","journal-title":"J Hosp Infect"},{"key":"10236_CR37","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1038\/s44161-022-00049-1","volume":"1","author":"Z Mallat","year":"2022","unstructured":"Mallat Z, Binder CJ. The why and how of adaptive immune responses in ischemic cardiovascular disease. Nat Cardiovasc Res. 2022;1:431\u201344.","journal-title":"Nat Cardiovasc Res"},{"key":"10236_CR38","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1016\/j.cmi.2019.02.026","volume":"25","author":"JA Otter","year":"2019","unstructured":"Otter JA, et al. Individual- and community-level risk factors for ESBL Enterobacteriaceae colonization identified by universal admission screening in London. Clin Microbiol Infect. 2019;25:1259\u201365.","journal-title":"Clin Microbiol Infect"},{"key":"10236_CR39","doi-asserted-by":"publisher","first-page":"1269","DOI":"10.1016\/j.ajic.2016.03.034","volume":"44","author":"GM Snyder","year":"2016","unstructured":"Snyder GM, et al. Factors associated with the receipt of antimicrobials among chronic hemodialysis patients. Am J Infect Control. 2016;44:1269\u201374.","journal-title":"Am J Infect Control"},{"key":"10236_CR40","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1186\/s12879-024-09726-x","volume":"24","author":"MAT Ibaideya","year":"2024","unstructured":"Ibaideya MAT, Taha AA, Qadi M. Phenotypic and molecular characterization of multidrug-resistant Enterobacterales isolated from clinical samples in Palestine: a focus on extended-spectrum \u03b2-lactamase- and carbapenemase-producing isolates. BMC Infect Dis. 2024;24:812.","journal-title":"BMC Infect Dis"}],"container-title":["BMC Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-024-10236-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12879-024-10236-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12879-024-10236-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T11:03:41Z","timestamp":1732273421000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-024-10236-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,22]]},"references-count":40,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["10236"],"URL":"https:\/\/doi.org\/10.1186\/s12879-024-10236-z","relation":{},"ISSN":["1471-2334"],"issn-type":[{"value":"1471-2334","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,22]]},"assertion":[{"value":"17 July 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was conducted with the full approval of the Institutional Review Board (IRB) at An-Najah National University (Ref: Med. Sept. 2023\/2). The IRB reviewed all aspects of the study protocol, including procedures for accessing and utilizing patient clinical information. All collected data were employed exclusively for this clinical research project and were maintained with strict confidentiality. Patient data and hospital details were anonymized through a coding system, allowing access to the information only for authorized research staff to maintain confidentiality. Written informed consent was obtained from each participant before their inclusion in the study. The research methodology followed all relevant ethical guidelines and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All authors approved the manuscript and gave their consent for submission and publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1334"}}