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Differentiating between wound contamination and true fungal infection remains a clinical challenge, with limited guidance on the use of prophylactic antifungal therapy in this setting. This article presents a rare case of an immunocompetent patient who sustained a degloving hand injury and radius fracture from a bread kneading machine, with subsequent deep tissue cultures growing\n                    <jats:italic>Saccharomyces cerevisiae<\/jats:italic>\n                    . The case underscores the potential risk of fungal infection in occupational injuries involving dough and emphasizes the importance of early identification and consideration of prophylactic antifungal treatment in similar scenarios.\n                  <\/jats:p>","DOI":"10.1186\/s12879-026-12764-2","type":"journal-article","created":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T17:14:49Z","timestamp":1771089289000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Saccharomyces cerevisiae isolated in a degloving baker\u2019s machine injury, a contamination or infection \u2013 a case report"],"prefix":"10.1186","volume":"26","author":[{"given":"Heloi","family":"Stefani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel Hanawa","family":"Morisaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boanerge Ojeda","family":"Ch.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhu Babu","family":"Adusumilli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angel Lorenzo","family":"Porras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maha","family":"Albukhari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Folusakin","family":"Ayoade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,14]]},"reference":[{"issue":"11","key":"12764_CR1","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1086\/429916","volume":"40","author":"P Mu\u00f1oz","year":"2005","unstructured":"Mu\u00f1oz P, Bouza E, Cuenca-Estrella M, et al. Saccharomyces cerevisiae fungemia: an emerging infectious disease. Clin Infect Dis. 2005;40(11):1625\u201334. https:\/\/doi.org\/10.1086\/429916. Epub 2005 Apr 25. PMID: 15889360.","journal-title":"Clin Infect Dis"},{"issue":"9","key":"12764_CR2","doi-asserted-by":"publisher","first-page":"430","DOI":"10.5005\/jp-journals-10071-23239","volume":"23","author":"P Gupta","year":"2019","unstructured":"Gupta P, Singh YP, Taneja A. A friend or foe in ICU (A case report with Solution). Indian J Crit Care Med. 2019;23(9):430\u20131. https:\/\/doi.org\/10.5005\/jp-journals-10071-23239. PMID: 31645830; PMCID: PMC6775723. Saccharomyces.","journal-title":"Indian J Crit Care Med"},{"key":"12764_CR3","doi-asserted-by":"publisher","unstructured":"Aucott JN, Fayen J, Grossnicklas H, Morrissey A, Lederman MM, Salata RA. Invasive infection with Saccharomyces cerevisiae: report of three cases and review. 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IDCases. 2016;5:1\u20133. https:\/\/doi.org\/10.1016\/j.idcr.2016.05.002. PMID: 27347482; PMCID: PMC4909721.","journal-title":"IDCases"},{"key":"12764_CR6","doi-asserted-by":"crossref","unstructured":"P\u00e9rez-Cantero A, Thomson P, Paredes K, Guarro J, Capilla J. Antifungal susceptibility of Saccharomyces cerevisiae and therapy in a murine model of disseminated infection. Rev Iberoam Micol. 2019 Jan-Mar;36(1):37\u201340. doi: 10.1016\/j.riam.2018.04.004. Epub 2019 Feb 11. PMID: 30765275.","DOI":"10.1016\/j.riam.2018.04.004"},{"issue":"2","key":"12764_CR7","doi-asserted-by":"publisher","first-page":"168","DOI":"10.3390\/jof9020168","volume":"9","author":"S Toepfer","year":"2023","unstructured":"Toepfer S, Lackner M, Keniya MV, Monk BC. Functional expression of Recombinant Candida auris proteins in Saccharomyces cerevisiae enables Azole susceptibility evaluation and drug discovery. J Fungi (Basel). 2023;9(2):168. https:\/\/doi.org\/10.3390\/jof9020168. 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Informed consent was obtained from the patient to be included in the study. Every effort has been made to anonymize the case.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent has been obtained from the patient to publish this paper.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"605"}}