{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T18:55:19Z","timestamp":1781636119850,"version":"3.54.5"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"vor","delay-in-days":37,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Infect Dis"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Necrotizing fasciitis (NF) following minor trauma in healthy individuals is rare and poses a considerable diagnostic challenge. Due to its nonspecific early presentation, NF is associated with high rates of misdiagnosis and mortality, underscoring the critical need for early recognition and intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A previously healthy 37-year-old male developed rapidly progressive necrotizing fasciitis of the scrotum and right lower extremity following minor bicycle-related abrasions. Upon admission, the patient presented with a high-risk Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score of 8, and imaging studies demonstrated rapid spread of infection from the right inguinal region to the right lower extremity and perineum, with subsequent progression to septic shock and multiple organ dysfunction syndrome. Urgent multidisciplinary team (MDT) collaboration is critical. Through emergency fasciotomy and identification of Group A Streptococcus (GAS) infection, the diagnosis of NF was definitively established. Combined with high-dose penicillin G, and comprehensive supportive measures, he achieved complete recovery without sequelae at 6-month follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Type II NF related with GAS can even occurred in low-risk populations. Early diagnosis relies on LRINEC scoring combined with imaging. Time-critical MDT with immediate coordination for pathogen identificationis crucial for survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical trial number<\/jats:title>\n                    <jats:p>Not applicable.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12879-026-12889-4","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T09:38:10Z","timestamp":1771321090000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Case report: Necrotizing fasciitis involving the bilateral scrotum and right leg caused by Streptococcus pyogenes in a healthy male: a multidisciplinary diagnostic and therapeutic analysis"],"prefix":"10.1186","volume":"26","author":[{"given":"Xiaohua","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbo","family":"Xin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wuyunbilige","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,17]]},"reference":[{"key":"12889_CR1","doi-asserted-by":"publisher","first-page":"e52507","DOI":"10.2196\/52507","volume":"12","author":"RS Huang","year":"2023","unstructured":"Huang RS, Patil NS, Khan Y. Periorbital necrotizing fasciitis: case presentation. Interact J Med Res. 2023;12:e52507.","journal-title":"Interact J Med Res"},{"key":"12889_CR2","unstructured":"Zhu SB, Li DH, Shuntang L, et al. Analysis of clinical characteristics and treatment of patients with perianal necrotizing fasciitis. Chin J Burns Wounds. 2024:955\u201362."},{"key":"12889_CR3","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1159\/000490108","volume":"101","author":"SA Chernyadyev","year":"2018","unstructured":"Chernyadyev SA, Ufimtseva MA, Vishnevskaya IF, et al. Fournier\u2019s gangrene: literature review and clinical cases. Urol Int. 2018;101:91\u20137.","journal-title":"Urol Int"},{"key":"12889_CR4","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1055\/a-1319-1734","volume":"147","author":"A W\u00f6hler","year":"2022","unstructured":"W\u00f6hler A, Schwab R, G\u00fcsgen C, et al. [Diagnosis and treatment of severe fournier\u2019s gangrene: introduction of a surgical Approach, evaluation of risk Factors, Microbiological characteristics and review of the Literature]. Zentralbl Chir. 2022;147:480\u201391.","journal-title":"Zentralbl Chir"},{"key":"12889_CR5","doi-asserted-by":"publisher","first-page":"169","DOI":"10.3233\/CH-238119","volume":"86","author":"V Br\u00e9bant","year":"2024","unstructured":"Br\u00e9bant V, Eschenbacher E, Hitzenbichler F, Pemmerl S, Prantl L, Pawlik M. Pathogens and their resistance behavior in necrotizing fasciitis. Clin Hemorheol Microcirc. 2024;86:169\u201381.","journal-title":"Clin Hemorheol Microcirc"},{"key":"12889_CR6","first-page":"T11","volume":"66","author":"I P\u00e9rez-S\u00e1nchez","year":"2022","unstructured":"P\u00e9rez-S\u00e1nchez I, Mart\u00ednez-Gil L, Piqueras-Vidal PM, Pont-Guti\u00e9rez C, Cebri\u00e1n-G\u00f3mez R, Montoza-Nu\u00f1ez JM. [Translated article] necrotising fasciitis: management experience over the last two decades in our hospital. Rev Esp Cir Ortop Traumatol. 2022;66:T11\u20139.","journal-title":"Rev Esp Cir Ortop Traumatol"},{"key":"12889_CR7","doi-asserted-by":"publisher","first-page":"ofad117","DOI":"10.1093\/ofid\/ofad117","volume":"10","author":"PCK Tam","year":"2023","unstructured":"Tam PCK, Kennedy B, Ashokan A. Necrotizing soft tissue infections in South australia: A 15-Year review. Open Forum Infect Dis. 2023;10:ofad117.","journal-title":"Open Forum Infect Dis"},{"key":"12889_CR8","doi-asserted-by":"publisher","first-page":"6869","DOI":"10.2147\/IDR.S390008","volume":"15","author":"KF Zhang","year":"2022","unstructured":"Zhang KF, Shi CX, Chen SY, Wei W. Progress in multidisciplinary treatment of fournier\u2019s gangrene. Infect Drug Resist. 2022;15:6869\u201380.","journal-title":"Infect Drug Resist"},{"key":"12889_CR9","doi-asserted-by":"crossref","unstructured":"Wang J, Ma C, Li M, et al. 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The patient provided written informed consent for participation and publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The patient provided written informed consent for the publication of clinical details, images, and laboratory data. All authors consent to the submission of this manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"629"}}