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According to the rules of our institution, all patients are systematically informed for data collection and research purposes. According to our institutional review board, the included patients were specifically informed. In addition, all patients were enrolled in the registry of the French PH Network. This registry was set up in agreement with French Bioethics laws (Commission Nationale de l\u2019Informatique et des Libert\u00e9s; 842063). All patients provided written informed consent\/assent prior to genetic analysis.","order":1,"name":"Ethics","label":"Ethical approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"423"}}