{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:48:55Z","timestamp":1761562135641,"version":"3.37.3"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,8,5]],"date-time":"2016-08-05T00:00:00Z","timestamp":1470355200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2016,8,5]],"date-time":"2016-08-05T00:00:00Z","timestamp":1470355200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DK020541","K23 DK099438"],"award-info":[{"award-number":["DK020541","K23 DK099438"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["1 UL1 RR024160-01","1 UL1 RR024160-01"],"award-info":[{"award-number":["1 UL1 RR024160-01","1 UL1 RR024160-01"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Renal Research Institute","award":["Research Grant"],"award-info":[{"award-number":["Research Grant"]}]},{"DOI":"10.13039\/100001463","name":"american society of nephrology","doi-asserted-by":"publisher","award":["Carl W. Gottschalk Research Scholar Grant"],"award-info":[{"award-number":["Carl W. Gottschalk Research Scholar Grant"]}],"id":[{"id":"10.13039\/100001463","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Nephrol"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1186\/s12882-016-0331-6","type":"journal-article","created":{"date-parts":[[2016,8,5]],"date-time":"2016-08-05T09:57:30Z","timestamp":1470391050000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Effect of oral sodium bicarbonate on fibroblast growth factor-23 in patients with chronic kidney disease: a pilot study"],"prefix":"10.1186","volume":"17","author":[{"given":"Wei","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michal L.","family":"Melamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas H.","family":"Hostetter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn","family":"Bauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda C.","family":"Raff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony L.","family":"Almudevar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Lalonde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Messing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew K.","family":"Abramowitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,8,5]]},"reference":[{"issue":"1","key":"331_CR1","doi-asserted-by":"publisher","first-page":"E38","DOI":"10.1152\/ajpendo.00008.2006","volume":"291","author":"S Liu","year":"2006","unstructured":"Liu S, Zhou J, Tang W, Jiang X, Rowe DW, Quarles LD. Pathogenic role of Fgf23 in Hyp mice. Am J Physiol Endocrinol Metab. 2006;291(1):E38\u201349.","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"5","key":"331_CR2","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1172\/JCI18399","volume":"112","author":"M Riminucci","year":"2003","unstructured":"Riminucci M, Collins MT, Fedarko NS, Cherman N, Corsi A, White KE, et al. FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting. J Clin Invest. 2003;112(5):683\u201392.","journal-title":"J Clin Invest"},{"issue":"1","key":"331_CR3","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1152\/physrev.00002.2011","volume":"92","author":"A Martin","year":"2012","unstructured":"Martin A, David V, Quarles LD. Regulation and function of the FGF23\/klotho endocrine pathways. Physiol Rev. 2012;92(1):131\u201355.","journal-title":"Physiol Rev"},{"issue":"2","key":"331_CR4","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.bbrc.2003.12.102","volume":"314","author":"T Shimada","year":"2004","unstructured":"Shimada T, Urakawa I, Yamazaki Y, Hasegawa H, Hino R, Yoneya T, et al. FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa. Biochem Biophys Res Commun. 2004;314(2):409\u201314.","journal-title":"Biochem Biophys Res Commun"},{"issue":"1\u20132","key":"331_CR5","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/S0006-8993(10)80031-9","volume":"583","author":"LJ Ryan","year":"1992","unstructured":"Ryan LJ, Sanders DJ, Clark KB. Auto- and cross-correlation analysis of subthalamic nucleus neuronal activity in neostriatal- and globus pallidal-lesioned rats. Brain Res. 1992;583(1\u20132):253\u201361.","journal-title":"Brain Res"},{"issue":"7","key":"331_CR6","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1038\/ki.2012.176","volume":"82","author":"M Wolf","year":"2012","unstructured":"Wolf M. Update on fibroblast growth factor 23 in chronic kidney disease. Kidney Int. 2012;82(7):737\u201347.","journal-title":"Kidney Int"},{"issue":"12","key":"331_CR7","first-page":"4003","volume":"117","author":"IZ Ben-Dov","year":"2007","unstructured":"Ben-Dov IZ, Galitzer H, Lavi-Moshayoff V, Goetz R, Kuro-o M, Mohammadi M, et al. The parathyroid is a target organ for FGF23 in rats. J Clin Invest. 2007;117(12):4003\u20138.","journal-title":"J Clin Invest"},{"issue":"6","key":"331_CR8","doi-asserted-by":"publisher","first-page":"2272","DOI":"10.1046\/j.1523-1755.2003.00328.x","volume":"64","author":"T Larsson","year":"2003","unstructured":"Larsson T, Nisbeth U, Ljunggren O, Juppner H, Jonsson KB. Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers. Kidney Int. 2003;64(6):2272\u20139.","journal-title":"Kidney Int"},{"issue":"23","key":"331_CR9","doi-asserted-by":"publisher","first-page":"2432","DOI":"10.1001\/jama.2011.826","volume":"305","author":"T Isakova","year":"2011","unstructured":"Isakova T, Xie H, Yang W, Xie D, Anderson AH, Scialla J, et al. Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease. JAMA. 2011;305(23):2432\u20139.","journal-title":"JAMA"},{"issue":"9","key":"331_CR10","doi-asserted-by":"publisher","first-page":"2600","DOI":"10.1681\/ASN.2006080936","volume":"18","author":"D Fliser","year":"2007","unstructured":"Fliser D, Kollerits B, Neyer U, Ankerst DP, Lhotta K, Lingenhel A, et al. Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) Study. J Am Soc Nephrol. 2007;18(9):2600\u20138.","journal-title":"J Am Soc Nephrol"},{"issue":"10","key":"331_CR11","doi-asserted-by":"publisher","first-page":"1913","DOI":"10.1681\/ASN.2010121224","volume":"22","author":"J Kendrick","year":"2011","unstructured":"Kendrick J, Cheung AK, Kaufman JS, Greene T, Roberts WL, Smits G, et al. FGF-23 associates with death, cardiovascular events, and initiation of chronic dialysis. J Am Soc Nephrol. 2011;22(10):1913\u201322.","journal-title":"J Am Soc Nephrol"},{"issue":"6","key":"331_CR12","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1056\/NEJMoa0706130","volume":"359","author":"OM Gutierrez","year":"2008","unstructured":"Gutierrez OM, Mannstadt M, Isakova T, Rauh-Hain JA, Tamez H, Shah A, et al. Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med. 2008;359(6):584\u201392.","journal-title":"N Engl J Med"},{"issue":"3","key":"331_CR13","doi-asserted-by":"publisher","first-page":"F431","DOI":"10.1152\/ajprenal.00199.2012","volume":"303","author":"NS Krieger","year":"2012","unstructured":"Krieger NS, Culbertson CD, Kyker-Snowman K, Bushinsky DA. Metabolic acidosis increases fibroblast growth factor 23 in neonatal mouse bone. Am J Physiol Renal Physiol. 2012;303(3):F431\u20136.","journal-title":"Am J Physiol Renal Physiol"},{"issue":"5","key":"331_CR14","doi-asserted-by":"publisher","first-page":"714","DOI":"10.2215\/CJN.08340812","volume":"8","author":"MK Abramowitz","year":"2013","unstructured":"Abramowitz MK, Melamed ML, Bauer C, Raff AC, Hostetter TH. Effects of oral sodium bicarbonate in patients with CKD. Clin J Am Soc Nephrol. 2013;8(5):714\u201320.","journal-title":"Clin J Am Soc Nephrol."},{"issue":"4","key":"331_CR15","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1053\/j.ajkd.2010.02.337","volume":"55","author":"AS Levey","year":"2010","unstructured":"Levey AS, Stevens LA. Estimating GFR using the CKD Epidemiology Collaboration (CKD-EPI) creatinine equation: more accurate GFR estimates, lower CKD prevalence estimates, and better risk predictions. Am J Kidney Dis. 2010;55(4):622\u20137.","journal-title":"Am J Kidney Dis"},{"issue":"2","key":"331_CR16","doi-asserted-by":"publisher","first-page":"c94","DOI":"10.1159\/000086347","volume":"101","author":"H Nishi","year":"2005","unstructured":"Nishi H, Nii-Kono T, Nakanishi S, Yamazaki Y, Yamashita T, Fukumoto S, et al. Intravenous calcitriol therapy increases serum concentrations of fibroblast growth factor-23 in dialysis patients with secondary hyperparathyroidism. Nephron Clin Pract. 2005;101(2):c94\u20139.","journal-title":"Nephron Clin Pract"},{"issue":"6","key":"331_CR17","doi-asserted-by":"publisher","first-page":"2263","DOI":"10.1093\/ndt\/gfr668","volume":"27","author":"D Hansen","year":"2012","unstructured":"Hansen D, Rasmussen K, Pedersen SM, Rasmussen LM, Brandi L. Changes in fibroblast growth factor 23 during treatment of secondary hyperparathyroidism with alfacalcidol or paricalcitol. Nephrol Dial Transplant. 2012;27(6):2263\u20139.","journal-title":"Nephrol Dial Transplant"},{"issue":"10","key":"331_CR18","doi-asserted-by":"publisher","first-page":"2423","DOI":"10.1681\/ASN.2014030230","volume":"26","author":"CB Leibrock","year":"2015","unstructured":"Leibrock CB, Alesutan I, Voelkl J, Pakladok T, Michael D, Schleicher E, et al. NH4Cl treatment prevents tissue calcification in klotho deficiency. J Am Soc Nephrol. 2015;26(10):2423\u201333.","journal-title":"J Am Soc Nephrol."},{"issue":"11","key":"331_CR19","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1038\/nrneph.2013.111","volume":"9","author":"M Kuro-o","year":"2013","unstructured":"Kuro-o M. Klotho, phosphate and FGF-23 in ageing and disturbed mineral metabolism. Nat Rev Nephrol. 2013;9(11):650\u201360.","journal-title":"Nat Rev Nephrol"},{"issue":"6655","key":"331_CR20","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1038\/36285","volume":"390","author":"M Kuro-o","year":"1997","unstructured":"Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature. 1997;390(6655):45\u201351.","journal-title":"Nature"},{"issue":"4","key":"331_CR21","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1053\/j.ajkd.2013.01.017","volume":"62","author":"M Dobre","year":"2013","unstructured":"Dobre M, Yang W, Chen J, Drawz P, Hamm LL, Horwitz E, et al. Association of serum bicarbonate with risk of renal and cardiovascular outcomes in CKD: a report from the Chronic Renal Insufficiency Cohort (CRIC) study. Am J Kidney Dis. 2013;62(4):670\u20138.","journal-title":"Am J Kidney Dis"},{"key":"331_CR22","doi-asserted-by":"publisher","unstructured":"Dobre M, Yang W, Pan Q, Appel L, Bellovich K, Chen J, et al. Persistent high serum bicarbonate and the risk of heart failure in patients with chronic kidney disease (CKD): A report from the Chronic Renal Insufficiency Cohort (CRIC) study. J Am Heart Assoc. 2015;4(4). doi:\n                    10.1161\/JAHA\n                    \n                  .","DOI":"10.1161\/JAHA"},{"issue":"11","key":"331_CR23","doi-asserted-by":"publisher","first-page":"4393","DOI":"10.1172\/JCI46122","volume":"121","author":"C Faul","year":"2011","unstructured":"Faul C, Amaral AP, Oskouei B, Hu MC, Sloan A, Isakova T, et al. FGF23 induces left ventricular hypertrophy. J Clin Invest. 2011;121(11):4393\u2013408.","journal-title":"J Clin Invest"},{"issue":"6","key":"331_CR24","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.1016\/j.cmet.2015.09.002","volume":"22","author":"A Grabner","year":"2015","unstructured":"Grabner A, Amaral AP, Schramm K, Singh S, Sloan A, Yanucil C, et al. Activation of cardiac fibroblast growth factor receptor 4 causes left ventricular hypertrophy. Cell Metab. 2015;22(6):1020\u201332.","journal-title":"Cell Metab"},{"issue":"5","key":"331_CR25","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.pcad.2006.02.001","volume":"48","author":"AH Gradman","year":"2006","unstructured":"Gradman AH, Alfayoumi F. From left ventricular hypertrophy to congestive heart failure: management of hypertensive heart disease. Prog Cardiovasc Dis. 2006;48(5):326\u201341.","journal-title":"Prog Cardiovasc Dis"},{"issue":"1","key":"331_CR26","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/ajcn\/41.1.52","volume":"41","author":"JJ Castenmiller","year":"1985","unstructured":"Castenmiller JJ, Mensink RP, van der Heijden L, Kouwenhoven T, Hautvast JG, de Leeuw PW, et al. The effect of dietary sodium on urinary calcium and potassium excretion in normotensive men with different calcium intakes. Am J Clin Nutr. 1985;41(1):52\u201360.","journal-title":"Am J Clin Nutr"},{"issue":"7","key":"331_CR27","first-page":"595","volume":"42","author":"C Shortt","year":"1988","unstructured":"Shortt C, Madden A, Flynn A, Morrissey PA. Influence of dietary sodium intake on urinary calcium excretion in selected Irish individuals. Eur J Clin Nutr. 1988;42(7):595\u2013603.","journal-title":"Eur J Clin Nutr"},{"issue":"3","key":"331_CR28","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1038\/ki.1982.168","volume":"22","author":"FP Muldowney","year":"1982","unstructured":"Muldowney FP, Freaney R, Moloney MF. Importance of dietary sodium in the hypercalciuria syndrome. Kidney Int. 1982;22(3):292\u20136.","journal-title":"Kidney Int"},{"issue":"4","key":"331_CR29","doi-asserted-by":"publisher","first-page":"F882","DOI":"10.1152\/ajprenal.00360.2010","volume":"299","author":"V Lavi-Moshayoff","year":"2010","unstructured":"Lavi-Moshayoff V, Wasserman G, Meir T, Silver J, Naveh-Many T. PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop. Am J Physiol Renal Physiol. 2010;299(4):F882\u20139.","journal-title":"Am J Physiol Renal Physiol"},{"issue":"5","key":"331_CR30","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1038\/ki.2011.107","volume":"80","author":"I Lopez","year":"2011","unstructured":"Lopez I, Rodriguez-Ortiz ME, Almaden Y, Guerrero F, de Oca AM, Pineda C, et al. Direct and indirect effects of parathyroid hormone on circulating levels of fibroblast growth factor 23 in vivo. Kidney Int. 2011;80(5):475\u201382.","journal-title":"Kidney Int"},{"issue":"6","key":"331_CR31","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1002\/emmm.201303716","volume":"6","author":"O Andrukhova","year":"2014","unstructured":"Andrukhova O, Slavic S, Smorodchenko A, Zeitz U, Shalhoub V, Lanske B, et al. FGF23 regulates renal sodium handling and blood pressure. EMBO Mol Med. 2014;6(6):744\u201359.","journal-title":"EMBO Mol Med"},{"issue":"9","key":"331_CR32","doi-asserted-by":"publisher","first-page":"2075","DOI":"10.1681\/ASN.2008111205","volume":"20","author":"I de Brito-Ashurst","year":"2009","unstructured":"de Brito-Ashurst I, Varagunam M, Raftery MJ, Yaqoob MM. Bicarbonate supplementation slows progression of CKD and improves nutritional status. J Am Soc Nephrol. 2009;20(9):2075\u201384.","journal-title":"J Am Soc Nephrol."},{"issue":"4","key":"331_CR33","doi-asserted-by":"publisher","first-page":"581","DOI":"10.2215\/CJN.07640711","volume":"7","author":"B Di Iorio","year":"2012","unstructured":"Di Iorio B, Di Micco L, Torraca S, Sirico ML, Russo L, Pota A, et al. Acute effects of very-low-protein diet on FGF23 levels: a randomized study. Clin J Am Soc Nephrol. 2012;7(4):581\u20137.","journal-title":"Clin J Am Soc Nephrol."},{"issue":"8","key":"331_CR34","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.1359\/jbmr.060507","volume":"21","author":"SM Burnett","year":"2006","unstructured":"Burnett SM, Gunawardene SC, Bringhurst FR, Juppner H, Lee H, Finkelstein JS. Regulation of C-terminal and intact FGF-23 by dietary phosphate in men and women. J Bone Miner Res Off J Am Soc Bone Miner Res. 2006;21(8):1187\u201396.","journal-title":"J Bone Miner Res Off J Am Soc Bone Miner Res."},{"issue":"3","key":"331_CR35","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1210\/jc.2004-1039","volume":"90","author":"SL Ferrari","year":"2005","unstructured":"Ferrari SL, Bonjour JP, Rizzoli R. Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men. J Clin Endocrinol Metab. 2005;90(3):1519\u201324.","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"331_CR36","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1053\/j.ajkd.2014.10.014","volume":"65","author":"GA Block","year":"2015","unstructured":"Block GA, Fishbane S, Rodriguez M, Smits G, Shemesh S, Pergola PE, et al. A 12-week, double-blind, placebo-controlled trial of ferric citrate for the treatment of iron deficiency anemia and reduction of serum phosphate in patients with CKD Stages 3\u20135. Am J Kidney Dis. 2015;65(5):728\u201336.","journal-title":"Am J Kidney Dis."},{"issue":"11","key":"331_CR37","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1038\/ki.2009.24","volume":"75","author":"M Ohnishi","year":"2009","unstructured":"Ohnishi M, Nakatani T, Lanske B, Razzaque MS. Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase. Kidney Int. 2009;75(11):1166\u201372.","journal-title":"Kidney Int"},{"issue":"6","key":"331_CR38","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1007\/s00774-007-0779-3","volume":"25","author":"N Ito","year":"2007","unstructured":"Ito N, Fukumoto S, Takeuchi Y, Takeda S, Suzuki H, Yamashita T, et al. Effect of acute changes of serum phosphate on fibroblast growth factor (FGF)23 levels in humans. J Bone Miner Metab. 2007;25(6):419\u201322.","journal-title":"J Bone Miner Metab"},{"issue":"2 Suppl 1","key":"331_CR39","first-page":"S1","volume":"39","author":"KF National","year":"2002","unstructured":"National KF. K\/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002;39(2 Suppl 1):S1\u2013266.","journal-title":"Am J Kidney Dis."},{"issue":"3","key":"331_CR40","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1038\/ki.2010.129","volume":"78","author":"A Mahajan","year":"2010","unstructured":"Mahajan A, Simoni J, Sheather SJ, Broglio KR, Rajab MH, Wesson DE. Daily oral sodium bicarbonate preserves glomerular filtration rate by slowing its decline in early hypertensive nephropathy. Kidney Int. 2010;78(3):303\u20139.","journal-title":"Kidney Int"},{"issue":"2","key":"331_CR41","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1053\/j.ajkd.2013.06.017","volume":"63","author":"W Chen","year":"2014","unstructured":"Chen W, Abramowitz MK. Treatment of metabolic acidosis in patients with CKD. Am J Kidney Dis. 2014;63(2):311\u20137.","journal-title":"Am J Kidney Dis."}],"container-title":["BMC Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-016-0331-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12882-016-0331-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-016-0331-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-016-0331-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T14:39:36Z","timestamp":1589467176000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcnephrol.biomedcentral.com\/articles\/10.1186\/s12882-016-0331-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,5]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["331"],"URL":"https:\/\/doi.org\/10.1186\/s12882-016-0331-6","relation":{},"ISSN":["1471-2369"],"issn-type":[{"type":"electronic","value":"1471-2369"}],"subject":[],"published":{"date-parts":[[2016,8,5]]},"assertion":[{"value":"4 April 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 August 2016","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2016","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"114"}}