{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T17:04:12Z","timestamp":1794330252755,"version":"4.9.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T00:00:00Z","timestamp":1600819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T00:00:00Z","timestamp":1600819200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Nephrol"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Concurrent type 1 diabetes mellitus (T1DM) and idiopathic nephrotic syndrome is rare, and most previously reported cases were in children. We report the case of an adult woman who developed T1DM and minimal change nephrotic syndrome (MCNS) nearly simultaneously.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 24-year-old woman had first presented to another hospital with nausea, vomiting, and fatigue. She was diagnosed with diabetic ketoacidosis and T1DM on the basis of her hyperglycemia, ketoacidosis, and positive anti-glutamic acid decarboxylase antibody test result. Rapid infusion of normal saline and insulin administration alleviated hyperglycemia and ketoacidosis. Two weeks after admission, however, she developed nephrotic syndrome (NS) with rapidly decreasing urine volume. She was referred to our hospital with a diagnosis of acute kidney injury. Although she temporarily required dialysis and high doses of insulin, within 1\u2009month NS and acute kidney injury had been alleviated by oral prednisolone and low-density lipoprotein apheresis. Renal biopsy showed minor glomerular abnormalities without diabetic nephropathy, so we diagnosed her with MCNS. Seven weeks after the discharge, NS relapsed, and cyclosporine was added to prednisolone. However, NS relapsed twice within the next 4\u2009months, so we started her on rituximab. At 6\u2009months after initiating rituximab therapy, she remained in complete remission.<\/jats:p>\n                <jats:p>Her mother also had T1DM but not MCNS. The patient had HLA-DRB1*09:01\/09:01, DQB1*03:03\/03:03, and her mother had HLA-DRB1*04:05\/09:01, DQB1*03:03\/04:01.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Concurrent T1DM and MCNS is rare and their coexistence might be coincidental. Alternatively, they might have been caused by an underlying, unidentified genetic predisposition. Previous reports and our patient\u2019s findings suggest that specific HLA alleles and haplotypes or a Th1\/Th2 imbalance might be associated with T1DM and MCNS that occurred nearly simultaneously.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12882-020-02071-6","type":"journal-article","created":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T11:03:39Z","timestamp":1600859019000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Concurrent minimal change nephrotic syndrome and type 1 diabetes mellitus in an adult Japanese woman: a case report"],"prefix":"10.1186","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8185-618X","authenticated-orcid":false,"given":"Ryuzoh","family":"Nishizono","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Kogou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuri","family":"Ishizaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Minakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masao","family":"Kikuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko","family":"Inagaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shouichi","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,9,23]]},"reference":[{"issue":"7","key":"2071_CR1","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1111\/dme.13295","volume":"34","author":"Y Onda","year":"2017","unstructured":"Onda Y, Sugihara S, Ogata T, Yokoya S, Yokoyama T, Tajima N. Type 1 diabetes (T1D) study group. Incidence and prevalence of childhood-onset type 1 diabetes in Japan: the T1D study. Diabet Med. 2017;34(7):909\u201315.","journal-title":"Diabet Med"},{"issue":"1","key":"2071_CR2","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1007\/s00592-016-0909-2","volume":"54","author":"M Songini","year":"2017","unstructured":"Songini M, Mannu C, Targhetta C, Bruno G. Type 1 diabetes in Sardinia: facts and hypotheses in the context of worldwide epidemiological data. Acta Diabetol. 2017;54(1):9\u201317.","journal-title":"Acta Diabetol"},{"issue":"4","key":"2071_CR3","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1007\/s10157-016-1319-z","volume":"21","author":"K Kikunaga","year":"2017","unstructured":"Kikunaga K, Ishikura K, Terano C, Sato M, Komaki F, Hamasaki Y, et al. Japanese pediatric survey holding information of NEphrotic syndrome study of the Japanese study Group of Renal Disease in children (JP-SHINE study). High incidence of idiopathic nephrotic syndrome in east Asian children: a nationwide survey in Japan. Clin Exp Nephrol. 2017;21(4):651\u20137.","journal-title":"Clin Exp Nephrol"},{"key":"2071_CR4","doi-asserted-by":"publisher","first-page":"39","DOI":"10.3389\/fped.2016.00039","volume":"4","author":"R Chanchlani","year":"2016","unstructured":"Chanchlani R, Parekh RS. Ethnic differences in childhood nephrotic syndrome. Front Pediatr. 2016;4:39.","journal-title":"Front Pediatr"},{"key":"2071_CR5","doi-asserted-by":"crossref","first-page":"2050313X1982773","DOI":"10.1177\/2050313X19827734","volume":"7","author":"NS Bawahab","year":"2019","unstructured":"Bawahab NS, Safdar OY, Nagadi SA, Saeedi AT, Mohammed Hussain RW. Nephrotic syndrome co-existing with type 1 diabetes in a 12-year-old boy: Case report and literature review. SAGE Open Med Case Rep. 2019;7:2050313X19827734.","journal-title":"SAGE Open Med Case Rep"},{"issue":"4","key":"2071_CR6","first-page":"25","volume":"2","author":"H Otukesh","year":"2016","unstructured":"Otukesh H, Torabi A, Hoseini R, Rahimabad PK, Mehrazma M. Co-existance of type 1 diabetes mellitus and nephrotic syndrome with membranous glomerulonephritis in a 6-year old boy: report of a case. Int J Children Adolesc. 2016;2(4):25\u20137.","journal-title":"Int J Children Adolesc"},{"issue":"6","key":"2071_CR7","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1590\/S0021-75572003000600016","volume":"79","author":"EA Rego Filho","year":"2003","unstructured":"Rego Filho EA, Mello SF, Omuro AM, Loli JO. Simultaneous onset of steroid-sensitive nephrotic syndrome and type 1 diabetes. J Pediatr. 2003;79(6):557\u201360.","journal-title":"J Pediatr"},{"issue":"5","key":"2071_CR8","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1007\/s00467-002-0837-y","volume":"17","author":"M Goldman","year":"2002","unstructured":"Goldman M, H\u00e9bert D, Geary DF. Management of steroid-sensitive nephrotic syndrome in children with type 1 diabetes. Pediatr Nephrol. 2002;17(5):351\u20134.","journal-title":"Pediatr Nephrol"},{"issue":"4","key":"2071_CR9","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1111\/j.1464-5491.1988.tb01010.x","volume":"5","author":"TL Dornan","year":"1988","unstructured":"Dornan TL, Jenkins S, Cotton RE, Tattersall RB, Burden RP, et al. The nephrotic syndrome at presentation of insulin-dependent diabetes mellitus; cause or coincidence? Diabet Med. 1988;5(4):387\u201390.","journal-title":"Diabet Med"},{"key":"2071_CR10","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/S0272-6386(97)90498-4","volume":"30","author":"LA Robinson","year":"1997","unstructured":"Robinson LA, Howel DN, Wigfall DR, Foreman JW. Appearance of immune complex glomerulonephritis following the onset of type 1 diabetes mellitus in a child. Am J Kidney Dis. 1997;30:713\u20136.","journal-title":"Am J Kidney Dis"},{"issue":"4","key":"2071_CR11","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1056\/NEJM196907242810401","volume":"281","author":"RE Urizar","year":"1969","unstructured":"Urizar RE, Schwartz A, Top F Jr, Vernier RL. The nephrotic syndrome in children with diabetes mellitus of recent onset. N Engl J Med. 1969;281(4):173\u201381.","journal-title":"N Engl J Med"},{"key":"2071_CR12","first-page":"80","volume":"85","author":"GC Robinson","year":"1961","unstructured":"Robinson GC, McConnell D. Simultaneous onset of diabetes mellitus and nephrotic syndrome. Can M A J. 1961;85:80\u20131.","journal-title":"Can M A J"},{"key":"2071_CR13","first-page":"991","volume":"39","author":"FC Goetz","year":"1960","unstructured":"Goetz FC, Hartmann JF, Lazarow A. Electron microscopy of the human glomerulus in early diabetes. J Clin Invest. 1960;39:991.","journal-title":"J Clin Invest"},{"issue":"22","key":"2071_CR14","doi-asserted-by":"publisher","first-page":"2143","DOI":"10.1056\/NEJMoa0904452","volume":"361","author":"MD Pescovitz","year":"2009","unstructured":"Pescovitz MD, Greenbaum CJ, Krause-Steinrauf H, Becker DJ, Gitelman SE, Goland R, et al. Rituximab, B-lymphocyte depletion, and preservation of beta-cell function. N Engl J Med. 2009;361(22):2143\u201352.","journal-title":"N Engl J Med"},{"key":"2071_CR15","doi-asserted-by":"publisher","unstructured":"Kurozumi A, Okada Y, Arao T, Miyazaki Y, Yoshikawa M, Torimoto K, et al. Pancreas-protective effect of rituximab for acute-onset type 1 diabetes in the honeymoon period: a case report. Endocrinol Diabetes Metab Case Rep. 2016;160020. https:\/\/doi.org\/10.1530\/EDM-16-0020.","DOI":"10.1530\/EDM-16-0020"},{"key":"2071_CR16","doi-asserted-by":"publisher","first-page":"1692","DOI":"10.1056\/NEJMoa012864","volume":"346","author":"KC Herold","year":"2002","unstructured":"Herold KC, Hagopian W, Auger JA, et al. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N Engl J Med. 2002;346:1692\u20138.","journal-title":"N Engl J Med"},{"key":"2071_CR17","doi-asserted-by":"publisher","first-page":"2598","DOI":"10.1056\/NEJMoa043980","volume":"352","author":"B Keymeulen","year":"2005","unstructured":"Keymeulen B, Vandemeulebroucke E, Ziegler AG, et al. Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med. 2005;352:2598\u2013608.","journal-title":"N Engl J Med"},{"key":"2071_CR18","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1016\/S0140-6736(11)60886-6","volume":"378","author":"T Orban","year":"2011","unstructured":"Orban T, Bundy B, Becker DJ, et al. Type 1 diabetes TrialNet Abatacept study group co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial. Lancet. 2011;378:412\u20139.","journal-title":"Lancet"},{"issue":"2","key":"2071_CR19","doi-asserted-by":"publisher","first-page":"453","DOI":"10.2337\/dc13-0626","volume":"37","author":"MD Pescovitz","year":"2014","unstructured":"Pescovitz MD, Greenbaum CJ, Bundy B, Becker DJ, Gitelman SE, Goland R, et al. B-lymphocyte depletion with rituximab and \u03b2-cell function: two-year results. Diabetes Care. 2014;37(2):453\u20139.","journal-title":"Diabetes Care"},{"key":"2071_CR20","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.clim.2009.04.007","volume":"132","author":"KC Herold","year":"2009","unstructured":"Herold KC, Gitelman S, Greenbaum C, et al. Immune tolerance network ITN007AI study group treatment of patients with new onset type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years. Clin Immunol. 2009;132:166\u201373.","journal-title":"Clin Immunol"},{"key":"2071_CR21","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1007\/s00125-009-1644-9","volume":"53","author":"B Keymeulen","year":"2010","unstructured":"Keymeulen B, Walter M, Mathieu C, et al. Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass. Diabetologia. 2010;53:614\u201323.","journal-title":"Diabetologia."},{"issue":"4","key":"2071_CR22","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.2337\/dc13-0604","volume":"37","author":"T Orban","year":"2014","unstructured":"Orban T, Bundy B, Becker DJ, et al. Type 1 diabetes TrialNet Abatacept study group. Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: follow-up one year after cessation of treatment. Diabetes Care. 2014;37(4):1069\u201375.","journal-title":"Diabetes Care"},{"issue":"4","key":"2071_CR23","first-page":"312","volume":"53","author":"C Nakahara","year":"2000","unstructured":"Nakahara C, Kamoda T, Kinugasa H, et al. Simultaneous onset of nephrotic syndrome and insulin-dependent diabetes mellitus in a case with hypereosinophilia syndrome. Clin Nephrol. 2000;53(4):312\u20134.","journal-title":"Clin Nephrol"},{"issue":"8","key":"2071_CR24","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1515\/JPEM.2006.19.8.1045","volume":"19","author":"PI Agras","year":"2006","unstructured":"Agras PI, Kinik ST, Cengiz N, Baskin E. Type 1 diabetes mellitus associated with nephrotic syndrome. J Pediatr Endocrinol Metab. 2006;19(8):1045\u20138.","journal-title":"J Pediatr Endocrinol Metab"},{"key":"2071_CR25","doi-asserted-by":"publisher","unstructured":"Kari JA, El-Desoky SM, Mokhtar G, Jalalah SM. Simultaneous onset of steroid resistant nephrotic syndrome and IDDM in two young children. BMJ Case Rep. 2010:bcr0420102916. https:\/\/doi.org\/10.1136\/bcr.04.2010.2916.","DOI":"10.1136\/bcr.04.2010.2916"},{"key":"2071_CR26","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1159\/000184310","volume":"46","author":"R Peces","year":"1987","unstructured":"Peces R, Riera JR, Lopez Larrea C, Alvarez J. Steroid-responsive relapsing nephrotic syndrome associated with early diabetic glomerulopathy in a child. Nephron. 1987;46:78\u201382.","journal-title":"Nephron."},{"issue":"3","key":"2071_CR27","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1159\/000013479","volume":"19","author":"S Kagiyama","year":"1999","unstructured":"Kagiyama S, Tsuruta H, Tominaga M, Morishita K, Doi Y, Onoyma K. Minimal-change nephrotic syndrome and acute renal failure in a patient with aged onset insulin-dependent diabetes mellitus and autoimmune thyroiditis. Am J Nephrol. 1999;19(3):369\u201372.","journal-title":"Am J Nephrol"},{"key":"2071_CR28","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1196\/annals.1337.014","volume":"1037","author":"E Kawasaki","year":"2004","unstructured":"Kawasaki E, Eguchi K. Is type 1 diabetes in the Japanese population the same as among Caucasians? Ann N Y Acad Sci. 2004;1037:96\u2013103.","journal-title":"Ann N Y Acad Sci"},{"issue":"2","key":"2071_CR29","doi-asserted-by":"publisher","first-page":"545","DOI":"10.2337\/diabetes.51.2.545","volume":"51","author":"Y Kawabata","year":"2002","unstructured":"Kawabata Y, Ikegami H, Kawaguchi Y, Fujisawa T, Shintani M, Ono M, et al. Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and -DQ haplotypes to susceptibility to type 1 diabetes. Diabetes. 2002;51(2):545\u201351.","journal-title":"Diabetes."},{"issue":"8","key":"2071_CR30","doi-asserted-by":"publisher","first-page":"2189","DOI":"10.1681\/ASN.2017080859","volume":"29","author":"X Jia","year":"2018","unstructured":"Jia X, Horinouchi T, Hitomi Y, Shono A, Khor S, Omae Y, et al. Strong association of the HLA-DR\/DQ locus with childhood steroid-sensitive nephrotic syndrome in the Japanese population. J Am Soc Nephrol. 2018;29(8):2189\u201399.","journal-title":"J Am Soc Nephrol"},{"key":"2071_CR31","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1038\/ki.1991.232","volume":"40","author":"A Koyama","year":"1991","unstructured":"Koyama A, Fujisaki M, Kobayashi M, Igarashi M, Narita M. A glomerular permeability factor produced by human T cell hybridomas. Kidney Int. 1991;40:453\u201360.","journal-title":"Kidney Int"},{"key":"2071_CR32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00011-013-0672-6","volume":"63","author":"F Pereira Wde","year":"2014","unstructured":"Pereira Wde F, Brito-Melo GE, Guimaraes FT, Carvalho TG, et al. The role of the immune system in idiopathic nephrotic syndrome. A review of clinical and experimental studies. Inflamm Res. 2014;63:1\u201312.","journal-title":"Inflamm Res"},{"key":"2071_CR33","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1007\/s00467-006-0026-5","volume":"21","author":"CE Araya","year":"2006","unstructured":"Araya CE, Wasserfall CH, Brusko TM, Mu W, Segal MS, Johnson RJ, Garin EH. A case of unfulfilled expectations. Cytokines in idiopathic minimal lesion nephrotic syndrome. Pediatr Nephrol. 2006;21:603\u201310.","journal-title":"Pediatr Nephrol"},{"key":"2071_CR34","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1007\/s10157-010-0330-z","volume":"14","author":"T Kanai","year":"2010","unstructured":"Kanai T, Shiraishi H, Yamagata T, Ito T, Odaka J, Saito T, Aoyagi J, Momoi MY. Th2 cells predominate in idiopathic steroid-sensitive nephrotic syndrome. Clin Exp Nephrol. 2010;14:578\u201383.","journal-title":"Clin Exp Nephrol"},{"issue":"3","key":"2071_CR35","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1128\/CDLI.6.3.306-310.1999","volume":"6","author":"ST Azar","year":"1999","unstructured":"Azar ST, Tamim H, Beyhum HN, Habbal MZ, Almawi WY. Type 1 (insulin-dependent) diabetes is a Th1- and Th2-mediated autoimmune disease. Clin Diagn Lab Immunol. 1999;6(3):306\u201310.","journal-title":"Clin Diagn Lab Immunol"},{"key":"2071_CR36","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1136\/adc.56.7.517","volume":"56","author":"SR Meadow","year":"1981","unstructured":"Meadow SR, Sarsfield JK, Scott DG, Rajah SM. Steroid-responsive nephrotic syndrome and allergy: immunological studies. Arch Dis Child. 1981;56:517\u201324.","journal-title":"Arch Dis Child"},{"issue":"Suppl 2","key":"2071_CR37","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1159\/000182585","volume":"38","author":"WJ Riley","year":"1992","unstructured":"Riley WJ. Autoimmune polyglandular syndromes. Horn Res. 1992;38(Suppl 2):9\u201315.","journal-title":"Horn Res"},{"key":"2071_CR38","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1210\/jcem.84.5.5699","volume":"84","author":"WY Almawi","year":"1999","unstructured":"Almawi WY, Tamim H, Azar ST. T helper type 1 and 2 cytokines mediate the onset and progression of type 1 (insulin-dependent) diabetes. J Clin Endocrinol Metab. 1999;84:1497\u2013502.","journal-title":"J Clin Endocrinol Metab"},{"key":"2071_CR39","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1007\/s00467-017-3677-5","volume":"33","author":"M Colucci","year":"2018","unstructured":"Colucci M, Corpetti G, Emma F, Vivarelli M. Immunology of idiopathic nephrotic syndrome. Pediatr Nephrol. 2018;33:573\u201384.","journal-title":"Pediatr Nephrol"},{"issue":"1","key":"2071_CR40","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1210\/en.2006-0686","volume":"148","author":"A Viardot","year":"2007","unstructured":"Viardot A, Grey ST, Mackay F, Chisholm D. Potential antiinflammatory role of insulin via the preferential polarization of effector T cells toward a T helper 2 phenotype. Endocrinology. 2007;148(1):346\u201353.","journal-title":"Endocrinology"},{"issue":"7","key":"2071_CR41","doi-asserted-by":"publisher","first-page":"859","DOI":"10.2337\/diab.44.7.859","volume":"44","author":"P Gladstone","year":"1995","unstructured":"Gladstone P, Nepom GT. The prevention of IDDM. Injecting insulin into the cytokine network. Diabetes. 1995;44(7):859\u201362.","journal-title":"Diabetes."},{"issue":"4","key":"2071_CR42","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1055\/s-2007-978736","volume":"31","author":"A Kretowski","year":"1999","unstructured":"Kretowski A, My\u015bliwiec J, Szelachowska M, Kinalski M, Kinalska I. Insulin increases in vitro production of Th2 profile cytokines in peripheral blood cultures in subjects at high risk of diabetes type 1 and patients with newly diagnosed IDDM. Horm Metab Res. 1999;31(4):289\u201392.","journal-title":"Horm Metab Res"}],"container-title":["BMC Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-020-02071-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12882-020-02071-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-020-02071-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T23:26:45Z","timestamp":1632353205000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcnephrol.biomedcentral.com\/articles\/10.1186\/s12882-020-02071-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,23]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["2071"],"URL":"https:\/\/doi.org\/10.1186\/s12882-020-02071-6","relation":{},"ISSN":["1471-2369"],"issn-type":[{"value":"1471-2369","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,23]]},"assertion":[{"value":"19 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 September 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 September 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and accompanying images.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"410"}}