{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:29:14Z","timestamp":1762900154278,"version":"3.37.3"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T00:00:00Z","timestamp":1625529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T00:00:00Z","timestamp":1625529600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Private Universit\u00e4t Witten\/Herdecke gGmbH"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Nephrol"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>The ongoing coronavirus pandemic has major impacts on both patients and healthcare systems worldwide, thus creating new realities. Patients on maintenance dialysis listed for renal transplantation are a vulnerable subgroup with many comorbidities and recurring contacts with the healthcare system. Due to the COVID-19 pandemic transplant numbers have dropped considerably, further increasing waiting times in this high-risk population. On the other hand, knowledge of the severity of SARS-CoV-2 infection in immunocompromised patients, development and persistence of neutralising antibodies in such patients is just emerging. It is unclear how best to address the dilemma of postponing the life-saving transplantation.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We present a case report of a successful kidney transplantation only 65\u2009days after the recipient was hospitalized for treatment of COVID-19 pneumonia. In a follow up of 9\u2009months, we observed no signs of recurrent disease and transplant function is excellent. Monitoring SARS-CoV-2 antibody response demonstrates stable IgG levels.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This reassuring case provides guidance to transplant centers how to proceed with kidney transplantation safely during the pandemic. Careful consideration of risks and benefits of the organ offer, full recovery from COVID-19 symptoms and the presence of a positive SARS-CoV-2 IgG antibody test, qualifies for kidney transplantation.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12882-021-02448-1","type":"journal-article","created":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T09:03:11Z","timestamp":1625562191000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Renal transplantation after recovery from COVID-19 - a case report with implications for transplant programs in the face of the ongoing corona-pandemic"],"prefix":"10.1186","volume":"22","author":[{"given":"Katharina","family":"Tuschen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"Anders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amin","family":"Elfanish","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verena","family":"Schildgen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Schildgen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Ulrich","family":"Becker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7984-9597","authenticated-orcid":false,"given":"Alexander","family":"Weidemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,7,6]]},"reference":[{"key":"2448_CR1","doi-asserted-by":"publisher","first-page":"e95","DOI":"10.1016\/S0140-6736(20)31040-0","volume":"395","author":"A Loupy","year":"2020","unstructured":"Loupy A, et al. Organ procurement and transplantation during the COVID-19 pandemic. Lancet. 2020;395:e95\u20136. https:\/\/doi.org\/10.1016\/S0140-6736(20)31040-0.","journal-title":"Lancet"},{"issue":"10","key":"2448_CR2","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1111\/tri.13703","volume":"33","author":"G Varotti","year":"2020","unstructured":"Varotti G, Dodi F, Garibotto G, Fontana I. Successful kidney transplantation after COVID-19. Transpl Int. 2020;33(10):1333. https:\/\/doi.org\/10.1111\/tri.13703.","journal-title":"Transpl Int"},{"key":"2448_CR3","doi-asserted-by":"publisher","first-page":"1615","DOI":"10.1016\/j.kint.2020.09.004","volume":"98","author":"N Singh","year":"2020","unstructured":"Singh N, et al. Successful simultaneous pancreas and kidney transplant in a patient post-COVID-19 infection. Kidney Int. 2020;98:1615. https:\/\/doi.org\/10.1016\/j.kint.2020.09.004.","journal-title":"Kidney Int"},{"key":"2448_CR4","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.ijid.2020.03.003","volume":"93","author":"D Chen","year":"2020","unstructured":"Chen D, et al. Recurrence of positive SARS-CoV-2 RNA in COVID-19: A case report. Int J Infect Dis. 2020;93:297\u20139. https:\/\/doi.org\/10.1016\/j.ijid.2020.03.003.","journal-title":"Int J Infect Dis"},{"key":"2448_CR5","doi-asserted-by":"publisher","first-page":"2366","DOI":"10.1002\/jmv.26056","volume":"92","author":"VT Hoang","year":"2020","unstructured":"Hoang VT, Dao TL, Gautret P. Recurrence of positive SARS-CoV-2 in patients recovered from COVID-19. J Med Virol. 2020;92:2366. https:\/\/doi.org\/10.1002\/jmv.26056.","journal-title":"J Med Virol"},{"key":"2448_CR6","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1007\/s15010-020-01444-1","volume":"48","author":"D Loconsole","year":"2020","unstructured":"Loconsole D, et al. Recurrence of COVID-19 after recovery: a case report from Italy. Infection. 2020;48:965. https:\/\/doi.org\/10.1007\/s15010-020-01444-1.","journal-title":"Infection"},{"key":"2448_CR7","doi-asserted-by":"publisher","first-page":"1755","DOI":"10.1002\/jmv.25855","volume":"92","author":"AT Xiao","year":"2020","unstructured":"Xiao AT, Tong YX, Zhang S. False negative of RT-PCR and prolonged nucleic acid conversion in COVID-19: rather than recurrence. J Med Virol. 2020;92:1755. https:\/\/doi.org\/10.1002\/jmv.25855.","journal-title":"J Med Virol"},{"key":"2448_CR8","doi-asserted-by":"publisher","first-page":"2230","DOI":"10.1093\/cid\/ciaa398","volume":"71","author":"J Yuan","year":"2020","unstructured":"Yuan J, et al. PCR assays turned positive in 25 discharged COVID-19 patients. Clin Infect Dis. 2020;71:2230. https:\/\/doi.org\/10.1093\/cid\/ciaa398.","journal-title":"Clin Infect Dis"},{"key":"2448_CR9","doi-asserted-by":"publisher","first-page":"e14","DOI":"10.1016\/j.jinf.2020.03.001","volume":"80","author":"G Ye","year":"2020","unstructured":"Ye G, et al. Clinical characteristics of severe acute respiratory syndrome coronavirus 2 reactivation. J Inf Secur. 2020;80:e14\u20137. https:\/\/doi.org\/10.1016\/j.jinf.2020.03.001.","journal-title":"J Inf Secur"},{"key":"2448_CR10","doi-asserted-by":"publisher","unstructured":"To KK, et al. COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing. Clin Infect Dis. 2020. https:\/\/doi.org\/10.1093\/cid\/ciaa1275.","DOI":"10.1093\/cid\/ciaa1275"},{"key":"2448_CR11","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1111\/ajt.16330","volume":"21","author":"C Rouphael","year":"2021","unstructured":"Rouphael C, et al. Successful orthotopic liver transplantation in a patient with a positive SARS-CoV2 test and acute liver failure secondary to acetaminophen overdose. Am J Transplant. 2021;21:1312. https:\/\/doi.org\/10.1111\/ajt.16330.","journal-title":"Am J Transplant"},{"key":"2448_CR12","doi-asserted-by":"publisher","unstructured":"Murad H, et al. Repeat SARS-CoV-2 testing after recovery. Is a pretransplant PCR necessary? 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Am J Transplant. 2020;20:2997. https:\/\/doi.org\/10.1111\/ajt.16117.","journal-title":"Am J Transplant"}],"container-title":["BMC Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-021-02448-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12882-021-02448-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-021-02448-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T09:15:01Z","timestamp":1625562901000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcnephrol.biomedcentral.com\/articles\/10.1186\/s12882-021-02448-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,6]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["2448"],"URL":"https:\/\/doi.org\/10.1186\/s12882-021-02448-1","relation":{},"ISSN":["1471-2369"],"issn-type":[{"type":"electronic","value":"1471-2369"}],"subject":[],"published":{"date-parts":[[2021,7,6]]},"assertion":[{"value":"18 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 June 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 July 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Obtained in written form for clinical details.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"251"}}