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Western Kenya has similar climatic and occupational characteristics as many of those areas. The study objectives were to characterize prevalence and predictors of CKDu, such as, HIV, a known cause of CKD, in a sugarcane growing region of Kenya; and to estimate prevalence of CKDu across occupational categories and evaluate if physically demanding work or sugarcane work are associated with reduced eGFR.\n<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>The Disadvantaged Populations eGFR Epidemiology Study (DEGREE) protocol was followed in a cross-sectional study conducted in Kisumu County, Western Kenya. Multivariate logistic regression was performed to identify predictors of reduced eGFR.\n<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Among 782 adults the prevalence of eGFR\u2009&lt;\u200990 was 9.85%. Among the 612 participants without diabetes, hypertension, and heavy proteinuria the prevalence of eGFR\u2009&lt;\u200990 was 8.99% (95%CI 6.8%, 11.5%) and 0.33% (95%CI 0.04%, 1.2%) had eGFR\u2009&lt;\u200960. Among the 508 participants without known risk factors for reduced eGFR (including HIV), the prevalence of eGFR\u2009&lt;\u200990 was 5.12% (95%CI 3.4%, 7.4%); none had eGFR\u2009&lt;\u200960. Significant risk factors for reduced eGFR were sublocation, age, body mass index, and HIV. No association was found between reduced eGFR and work in the sugarcane industry, as a cane cutter, or in physically demanding occupations.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>CKDu is not a common public health problem in this population, and possibly this region. We recommend that future studies should consider HIV to be a known cause of reduced eGFR. Factors other than equatorial climate and work in agriculture may be important determinants of CKDu epidemics.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12882-023-03213-2","type":"journal-article","created":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T05:03:33Z","timestamp":1686027813000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prevalence and predictors of chronic kidney disease of undetermined causes (CKDu) in Western Kenya\u2019s \u201csugar belt\u201d: a cross-sectional study"],"prefix":"10.1186","volume":"24","author":[{"given":"Michelle","family":"H. Hathaway","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crystal","family":"L. 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