{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T16:26:19Z","timestamp":1764433579910,"version":"3.30.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T00:00:00Z","timestamp":1733097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T00:00:00Z","timestamp":1733097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Nephrol"],"DOI":"10.1186\/s12882-024-03890-7","type":"journal-article","created":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T13:09:44Z","timestamp":1733144984000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Sodium polystyrene sulfonate as an additional contributing factor to repeated gastric ulcers among other multiple factors in a patient undergoing hemodialysis: a case report"],"prefix":"10.1186","volume":"25","author":[{"given":"Yukiko","family":"Yasui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akio","family":"Nakashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kosuke","family":"Sasuga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Koike","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izumi","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshimi","family":"Ueda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goro","family":"Tokudome","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Ohkido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Yokoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,12,2]]},"reference":[{"issue":"3","key":"3890_CR1","first-page":"267","volume":"101","author":"KD Lillemoe","year":"1987","unstructured":"Lillemoe KD, Romolo JL, Hamilton SR, Pennington LR, Burdick JF, Williams GM. Intestinal Necrosis due to Sodium Polystyrene (Kayexalate) in Sorbitol Enemas: Clinical and Experimental Support for the Hypothesis. Surgery. 1987;101(3):267\u201372.","journal-title":"Surgery"},{"issue":"3","key":"3890_CR2","doi-asserted-by":"publisher","first-page":"264.e9","DOI":"10.1016\/j.amjmed.2012.08.016","volume":"126","author":"Ziv Harel","year":"2013","unstructured":"Harel Ziv, Harel Shai, Shah Prakesh S, Wald Ron, Perl Jeffrey, Bell Chaim M. Gastrointestinal Adverse Events with Sodium Polystyrene Sulfonate (Kayexalate) Use: A Systematic Review. The American Journal of Medicine. 2013;126(3):264.e9-24.","journal-title":"The American Journal of Medicine."},{"key":"3890_CR3","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1097\/00000478-199701000-00007","volume":"21","author":"A Rashid","year":"1997","unstructured":"Rashid A, Hamilton SR. Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol: an underrecognized condition. Am J Surg Pathol. 1997;21:60\u20139.","journal-title":"Am J Surg Pathol"},{"key":"3890_CR4","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/S0272-6386(12)80544-0","volume":"20","author":"B Gerstman","year":"1992","unstructured":"Gerstman B, Kirkman R, Platt R. Intestinal necrosis associated with postoperative orally administered sodium polystyrene sulfonate in sorbitol. Am J Kidney Dis. 1992;20:159\u201361.","journal-title":"Am J Kidney Dis"},{"key":"3890_CR5","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1159\/000111173","volume":"1","author":"M Pusztaszeri","year":"2007","unstructured":"Pusztaszeri M, Christodoulou M, Proietti S, Seelentag W. Kayexalate Intake (in Sorbitol) and Jejunal Diverticulitis, a Causative Role or an Innocent Bystander? Case Rep Gastroenterol. 2007;1:144\u201351.","journal-title":"Case Rep Gastroenterol"},{"key":"3890_CR6","doi-asserted-by":"publisher","first-page":"1518","DOI":"10.1093\/ndt\/gfz150","volume":"35","author":"P Laureati","year":"2020","unstructured":"Laureati P, Xu Y, Trevisan M, Schalin L, Mariani I, Bellocco R, et al. Initiation of sodium polystyrene sulphonate and the risk of gastrointestinal adverse events in advanced chronic kidney disease: a nationwide study. Nephrol Dail Transplant. 2020;35:1518\u201326.","journal-title":"Nephrol Dail Transplant"},{"key":"3890_CR7","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1053\/j.semdp.2014.02.007","volume":"31","author":"NC Panarelli","year":"2014","unstructured":"Panarelli NC. Druginduced injury in the gastrointestinal tract. Semin Diag Pathol. 2014;31:165\u201375.","journal-title":"Semin Diag Pathol"},{"key":"3890_CR8","first-page":"287","volume":"110","author":"J Hammer","year":"1998","unstructured":"Hammer J, Oesterreicher C, Hammer K, Koch U, Traindl O, Kovarik J. Chronic gastrointestinal symptoms in hemodialysis patients. Wien Klin Wochenschr. 1998;110:287\u201391.","journal-title":"Wien Klin Wochenschr"},{"key":"3890_CR9","doi-asserted-by":"publisher","first-page":"G998","DOI":"10.1152\/ajpgi.00529.2004","volume":"289","author":"JR Kovac","year":"2005","unstructured":"Kovac JR, Preiksaitis HG, Sims SM. Functional and molecular analysis of L-type calcium channels in human esophagus and lower esophageal sphincter smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2005;289:G998\u20131006.","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"3890_CR10","doi-asserted-by":"crossref","unstructured":"Hamada A, Ishii J, Doi K, Hamada N, Miyazaki C, Hamada T, et al. Increased Risk of Exacerbating Gastrointestinal Disease among Elderly Patients Following Treatment with Calcium Channel Blockers. J Clin Pharmacy Ther. 2008;33:619\u201324.","DOI":"10.1111\/j.1365-2710.2008.00958.x"},{"key":"3890_CR11","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/j.1365-2125.2007.02851.x","volume":"64","author":"J Hughes","year":"2007","unstructured":"Hughes J, Lockhart J, Joyce A. Do Calcium Antagonists Contribute to Gastro-Oesophageal Reflux Disease and Concomitant Noncardiac Chest Pain? Br J Clin Pharmacol. 2007;64:83\u20139.","journal-title":"Br J Clin Pharmacol"}],"container-title":["BMC Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-024-03890-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12882-024-03890-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-024-03890-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T14:05:08Z","timestamp":1733148308000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcnephrol.biomedcentral.com\/articles\/10.1186\/s12882-024-03890-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,2]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["3890"],"URL":"https:\/\/doi.org\/10.1186\/s12882-024-03890-7","relation":{},"ISSN":["1471-2369"],"issn-type":[{"value":"1471-2369","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,2]]},"assertion":[{"value":"20 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study is a case report and does not qualify as a clinical trial. Therefore, clinical trial registration is not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Informed consent was obtained from the patient for publication of this Case report and any accompanying images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"443"}}