{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T13:01:45Z","timestamp":1783947705256,"version":"3.55.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T00:00:00Z","timestamp":1734480000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T00:00:00Z","timestamp":1734480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Research and Publication Office\u2019 of the College of Medicine and Health Sciences, University of Gondar","award":["NA"],"award-info":[{"award-number":["NA"]}]},{"name":"Research and Publication Office\u2019 of the College of Medicine and Health Sciences, University of Gondar","award":["NA"],"award-info":[{"award-number":["NA"]}]},{"name":"Research and Publication Office\u2019 of the College of Medicine and Health Sciences, University of Gondar","award":["NA"],"award-info":[{"award-number":["NA"]}]},{"name":"Research and Publication Office\u2019 of the College of Medicine and Health Sciences, University of Gondar","award":["NA"],"award-info":[{"award-number":["NA"]}]},{"name":"Research and Publication Office\u2019 of the College of Medicine and Health Sciences, University of Gondar","award":["NA"],"award-info":[{"award-number":["NA"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Nephrol"],"DOI":"10.1186\/s12882-024-03914-2","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T11:27:44Z","timestamp":1734521264000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Acute kidney injury and its associated factors among patients with acute decompensated heart failure admitted to the university of Gondar Hospital, Northwest Ethiopia: a hospital-based cross-sectional study"],"prefix":"10.1186","volume":"25","author":[{"given":"Yinebeb","family":"Mezgebu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shitaye","family":"Alemu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Abdulkadir","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Habtewold","family":"Shibru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Workagegnehu","family":"Hailu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,18]]},"reference":[{"issue":"27","key":"3914_CR1","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","volume":"37","author":"P Ponikowski","year":"2016","unstructured":"Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS, et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2016;37(27):2129\u2013m2200.","journal-title":"Eur Heart J"},{"key":"3914_CR2","unstructured":"Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJV, Ponikowski P, Poole-Wilson PA, et al. The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart. Eur J Heart Fail. 2008;10(10):933\u201389. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008."},{"key":"3914_CR3","doi-asserted-by":"crossref","unstructured":"Savarese G, Lund LH. Global Public Health Burd Heart Fail Eoidemiology. 2017;7\u201311.","DOI":"10.15420\/cfr.2016:25:2"},{"key":"3914_CR4","doi-asserted-by":"crossref","unstructured":"Ntusi NB, Mayosi BM. Epidemiology of Heart Failure in sub-Saharan Africa. Expert Rev Cardiovasc Ther. 32457;7(2):169\u201380.","DOI":"10.1586\/14779072.7.2.169"},{"issue":"17","key":"3914_CR5","doi-asserted-by":"publisher","first-page":"1688","DOI":"10.1016\/j.jacc.2007.07.030","volume":"50","author":"A Damasceno","year":"2007","unstructured":"Damasceno A, Cotter G, Dzudie A, Sliwa K, Mayosi BM. Heart Failure in Sub-Saharan Africa: Time for Action. J Am Coll Cardiol. 2007;50(17):1688\u201393.","journal-title":"J Am Coll Cardiol"},{"issue":"18","key":"3914_CR6","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1001\/archinternmed.2012.3310","volume":"172","author":"A Damasceno","year":"2012","unstructured":"Damasceno A, Mayosi BM, Sani M, Ogah OS, Mondo C, Ojji D, et al. The causes, treatment, and outcome of acute heart failure in 1006 Africans from 9 countries: Results of the sub-Saharan Africa survey of heart failure. Arch Intern Med. 2012;172(18):1386\u201394.","journal-title":"Arch Intern Med"},{"key":"3914_CR7","doi-asserted-by":"publisher","unstructured":"Dokainish H, Teo K, Zhu J, Roy A, Alhabib KF, Elsayed A et al. Heart Failure in Africa, Asia, the Middle East and South America: The INTER-CHF study. Int J Cardiol [Internet]. 2016;204:133\u201341. https:\/\/doi.org\/10.1016\/j.ijcard.2015.11.183","DOI":"10.1016\/j.ijcard.2015.11.183"},{"issue":"3","key":"3914_CR8","doi-asserted-by":"publisher","first-page":"91","DOI":"10.2459\/JCM.0000000000000617","volume":"19","author":"TA Tsega","year":"2018","unstructured":"Tsega TA, Demissei BG. A systematic review of epidemiology, treatment and prognosis of heart failure in adults in Ethiopia. J Cardiovasc Med. 2018;19(3):91\u20137.","journal-title":"J Cardiovasc Med"},{"issue":"1","key":"3914_CR9","first-page":"50","volume":"30","author":"A Bane","year":"2016","unstructured":"Bane A, Bayisa T, Adamu F, Abdissa SG. Medical Admissions and Outcomes at Saint Paul\u2019s Hospital, Addis Ababa, Ethiopia: A retrospective study. Ethiop J Heal Dev. 2016;30(1):50\u20136.","journal-title":"Ethiop J Heal Dev"},{"issue":"9","key":"3914_CR10","first-page":"A602","volume":"20","author":"Y Tefera","year":"2017","unstructured":"Tefera Y, Abebe T, Abegaz T, Ab M. The Changing Trend of Cardiovascular Disease And Its Clinical Characteristics In Ethiopia:Hospital-Based Observational Study. Vasc Health Risk Manag. 2017;20(9):A602.","journal-title":"Vasc Health Risk Manag"},{"key":"3914_CR11","doi-asserted-by":"publisher","unstructured":"Schefold JC, Filippatos G, Hasenfuss G, Anker SD, Von Haehling S. Heart failure and kidney dysfunction: Epidemiology, mechanisms and management. Nat Rev Nephrol [Internet]. 2016;12(10):610\u201323. https:\/\/doi.org\/10.1038\/nrneph.2016.113","DOI":"10.1038\/nrneph.2016.113"},{"key":"3914_CR12","unstructured":"Jurgen Floege RJ, Johnson JF. Comprehensive Clinical Nephrology. Fourth edi. Saunders Elsevier; 2010. p. 797."},{"issue":"2","key":"3914_CR13","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1159\/000442300","volume":"6","author":"W Vandenberghe","year":"2015","unstructured":"Vandenberghe W, Gevaert S, Kellum JA, Bagshaw SM, Peperstraete H, Herck I, et al. Acute kidney injury in cardiorenal syndrome type 1 patients: A systematic review and meta-analysis. CardioRenal Med. 2015;6(2):116\u201328.","journal-title":"CardioRenal Med"},{"issue":"2","key":"3914_CR14","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.ahj.2004.08.005","volume":"149","author":"KF Adams","year":"2005","unstructured":"Adams KF, Fonarow GC, Emerman CL, LeJemtel TH, Costanzo MR, Abraham WT, et al. Characteristics and outcomes of patients hospitalized for heart failure in the United States: Rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE). Am Heart J. 2005;149(2):209\u201316.","journal-title":"Am Heart J"},{"key":"3914_CR15","doi-asserted-by":"publisher","unstructured":"Jeele MOO, Hussein AA, Mohamud MA, Adani AA, Mohamud MFY. Spectrum and prevalence of renal dysfunction among heart failure patients attending tertiary care hospital: first report from Somalia. Egypt J Intern Med [Internet]. 2023;35(1). https:\/\/doi.org\/10.1186\/s43162-023-00253-w","DOI":"10.1186\/s43162-023-00253-w"},{"issue":"1","key":"3914_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12872-019-01318-x","volume":"20","author":"M Tirfe","year":"2020","unstructured":"Tirfe M, Nedi T, Mekonnen D, Berha AB. Treatment outcome and its predictors among patients of acute heart failure at a tertiary care hospital in Ethiopia: A prospective observational study. BMC Cardiovasc Disord. 2020;20(1):1\u201310.","journal-title":"BMC Cardiovasc Disord"},{"key":"3914_CR17","doi-asserted-by":"publisher","unstructured":"Forman DE, Butler J, Wang Y, Abraham WT, O\u2019Connor CM, Gottlieb SS et al. Incidence, Predictors at Admission, and Impact of Worsening Renal Function among Patients Hospitalized with Heart Failure. J Am Coll Cardiol [Internet]. 2004;43(1):61\u20137. https:\/\/doi.org\/10.1016\/j.jacc.2003.07.031","DOI":"10.1016\/j.jacc.2003.07.031"},{"issue":"7","key":"3914_CR18","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1093\/eurheartj\/eht386","volume":"35","author":"K Damman","year":"2014","unstructured":"Damman K, Valente MAE, Voors AA, O\u2019Connor CM, Van Veldhuisen DJ, Hillege HL. Renal impairment, worsening renal function, and outcome in patients with heart failure: An updated meta-analysis. Eur Heart J. 2014;35(7):455\u201369.","journal-title":"Eur Heart J"},{"key":"3914_CR19","doi-asserted-by":"publisher","unstructured":"Gudsoorkar PS, Thakar CV. Acute Kidney Injury, Heart Failure, and Health Outcomes. Cardiol Clin [Internet]. 2019;37(3):297\u2013305. https:\/\/doi.org\/10.1016\/j.ccl.2019.04.005","DOI":"10.1016\/j.ccl.2019.04.005"},{"key":"3914_CR20","doi-asserted-by":"publisher","unstructured":"Ronco C, Bellasi A, Di Lullo L. Implication of Acute Kidney Injury in Heart Failure. Heart Fail Clin [Internet]. 2019;15(4):463\u201376. https:\/\/doi.org\/10.1016\/j.hfc.2019.05.002","DOI":"10.1016\/j.hfc.2019.05.002"},{"key":"3914_CR21","doi-asserted-by":"publisher","unstructured":"Correa A, Patel A, Chauhan K, Shah H, Saha A, Dave M et al. National Trends and Outcomes in Dialysis-Requiring Acute Kidney Injury in Heart Failure: 2002\u20132013. J Card Fail [Internet]. 2018;24(7):442\u201350. https:\/\/doi.org\/10.1016\/j.cardfail.2018.05.001","DOI":"10.1016\/j.cardfail.2018.05.001"},{"key":"3914_CR22","doi-asserted-by":"crossref","unstructured":"Voors AA, Davison BA, Felker GM, Ponikowski P, Unemori E, Cotter G et al. Early drop in systolic blood pressure and worsening renal function in acute heart failure: renal results of Pre-RELAX-AHF. Eur J Hear Fail. 2011;961\u20137.","DOI":"10.1093\/eurjhf\/hfr060"},{"issue":"10","key":"3914_CR23","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1093\/eurheartj\/ehi859","volume":"27","author":"MR Cowie","year":"2006","unstructured":"Cowie MR, Komajda M, Murray-Thomas T, Underwood J, Ticho B. Prevalence and impact of worsening renal function in patients hospitalized with decompensated heart failure: Results of the prospective outcomes study in heart failure (POSH). Eur Heart J. 2006;27(10):1216\u201322.","journal-title":"Eur Heart J"},{"issue":"1","key":"3914_CR24","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1159\/000099012","volume":"27","author":"H Chittineni","year":"2007","unstructured":"Chittineni H, Miyawaki N, Gulipelli S, Fishbane S. Risk for acute renal failure in patients hospitalized for decompensated congestive heart failure. Am J Nephrol. 2007;27(1):55\u201362.","journal-title":"Am J Nephrol"},{"issue":"5","key":"3914_CR25","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1016\/j.cardfail.2014.12.015","volume":"21","author":"G Berra","year":"2015","unstructured":"Berra G, Garin N, Stirnemann J, Jannot AS, Martin PY, Perrier A, et al. Outcome in acute heart failure: Prognostic value of acute kidney injury and worsening renal function. J Card Fail. 2015;21(5):382\u201390.","journal-title":"J Card Fail"},{"issue":"3","key":"3914_CR26","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1253\/circj.CJ-12-0994","volume":"77","author":"A Shirakabe","year":"2013","unstructured":"Shirakabe A, Hata N, Kobayashi N, Shinada T, Tomita K, Tsurumi M, et al. Prognostic impact of acute kidney injury in patients with acute decompensated heart failure. Circ J. 2013;77(3):687\u201396.","journal-title":"Circ J"},{"issue":"1","key":"3914_CR27","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/kisup.2012.3","volume":"2","author":"ISN","year":"2012","unstructured":"ISN. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int. 2012;2(1):3.","journal-title":"Kidney Int"},{"issue":"36","key":"3914_CR28","doi-asserted-by":"publisher","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","volume":"42","author":"TA McDonagh","year":"2021","unstructured":"McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, B\u00f6hm M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2021;42(36):3599\u2013726.","journal-title":"Eur Heart J"},{"key":"3914_CR29","doi-asserted-by":"publisher","unstructured":"Patel UD, Greiner MA, Fonarow GC, Phatak H, Hernandez AF, Curtis LH. Associations between worsening renal function and 30-day outcomes among Medicare beneficiaries hospitalized with heart failure. Am Heart J [Internet]. 2010;160(1):132\u2013138.e1. https:\/\/doi.org\/10.1016\/j.ahj.2010.03.033","DOI":"10.1016\/j.ahj.2010.03.033"},{"issue":"7","key":"3914_CR30","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1002\/ejhf.103","volume":"16","author":"MU Sani","year":"2014","unstructured":"Sani MU, Davison BA, Cotter G, Sliwa K, Edwards C, Liu L, et al. Renal dysfunction in African patients with acute heart failure. Eur J Heart Fail. 2014;16(7):718\u201328.","journal-title":"Eur J Heart Fail"},{"key":"3914_CR31","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1159\/000349969","volume":"182i","author":"M Haase","year":"2013","unstructured":"Haase M, M\u00fcller C, Damman K, Murray PT, Kellum JA, Ronco C, et al. Pathogenesis of cardiorenal syndrome type 1 in acute decompensated heart failure: Workgroup statements from the eleventh consensus conference of the acute dialysis quality initiative (ADQI). Contrib Nephrol. 2013;182i:99\u2013116.","journal-title":"Contrib Nephrol"},{"issue":"2","key":"3914_CR32","first-page":"146","volume":"20","author":"RS Chahal","year":"2020","unstructured":"Chahal RS, Chukwu CA, Kalra PR, Kalra PA. Heart failure and acute renal dysfunction in the cardiorenal syndrome. Clin Med J R Coll Physicians Lond. 2020;20(2):146\u201350.","journal-title":"Clin Med J R Coll Physicians Lond"},{"issue":"2","key":"3914_CR33","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/j.ahj.2003.08.012","volume":"147","author":"J Butler","year":"2004","unstructured":"Butler J, Forman DE, Abraham WT, Gottlieb SS, Loh E, Massie BM, et al. Relationship between heart failure treatment and development of worsening renal function among hospitalized patients. Am Heart J. 2004;147(2):331\u20138.","journal-title":"Am Heart J"},{"issue":"3","key":"3914_CR34","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1093\/ckj\/sfaa177","volume":"14","author":"J Gameiro","year":"2021","unstructured":"Gameiro J, Marques F, Lopes JA. Long-term consequences of acute kidney injury: A narrative review. Clin Kidney J. 2021;14(3):789\u2013804.","journal-title":"Clin Kidney J"},{"issue":"3","key":"3914_CR35","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1159\/000337714","volume":"2","author":"Z Eren","year":"2012","unstructured":"Eren Z, Ozveren O, Buvukoner E, Kaspar E, Degertekin M, Kantarci G. A Single-Centre Study of Acute Cardiorenal Syndrome: Incidence, Risk Factors and Consequences. Cardiorenal Med. 2012;2(3):168\u201376.","journal-title":"Cardiorenal Med"}],"container-title":["BMC Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-024-03914-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12882-024-03914-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-024-03914-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T12:02:27Z","timestamp":1734523347000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcnephrol.biomedcentral.com\/articles\/10.1186\/s12882-024-03914-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,18]]},"references-count":35,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["3914"],"URL":"https:\/\/doi.org\/10.1186\/s12882-024-03914-2","relation":{},"ISSN":["1471-2369"],"issn-type":[{"value":"1471-2369","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,18]]},"assertion":[{"value":"12 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval was obtained from the University of Gondar, School of Medicine Ethics Committee (Ref No.71207\/2021 Date: 04\/07\/2021). Written informed consent was obtained from each participant.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"461"}}