{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T14:27:15Z","timestamp":1793888835079,"version":"4.8.0"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T00:00:00Z","timestamp":1735776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T00:00:00Z","timestamp":1735776000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Korea university grant","award":["K2310531"],"award-info":[{"award-number":["K2310531"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Nephrol"],"DOI":"10.1186\/s12882-024-03924-0","type":"journal-article","created":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T00:17:47Z","timestamp":1735863467000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Neutrophil-to-lymphocyte ratio as a predictor for early mortality in older patients requiring hemodialysis; insights for hemodialysis access planning"],"prefix":"10.1186","volume":"26","author":[{"given":"Hyo Kee","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heungman","family":"Jun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1108-8381","authenticated-orcid":false,"given":"Sun-Young","family":"Ko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,2]]},"reference":[{"key":"3924_CR1","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/S0140-6736(20)30045-3","volume":"395","author":"GBD Chronic Kidney Disease Collaboration","year":"2020","unstructured":"GBD Chronic Kidney Disease Collaboration. Global, regional, and national burden of chronic kidney disease, 1990\u20132017: a systematic analysis for the global burden of disease study 2017. Lancet. 2020;395:709\u201333.","journal-title":"Lancet"},{"key":"3924_CR2","doi-asserted-by":"publisher","first-page":"1975","DOI":"10.1016\/S0140-6736(14)61601-9","volume":"385","author":"T Liyanage","year":"2015","unstructured":"Liyanage T, Ninomiya T, Jha V, Neal B, Patrice HM, Okpechi I, Zhao MH, Lv J, Garg AX, Knight J, Rodgers A, Gallagher M, Kotwal S, Cass A, Perkovic V. Worldwide access to treatment for end-stage kidney disease: a systematic review. Lancet. 2015;385:1975\u201382.","journal-title":"Lancet"},{"key":"3924_CR3","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1053\/j.ajkd.2019.12.001","volume":"75","author":"CE Lok","year":"2020","unstructured":"Lok CE, Huber TS, Lee T, Shenoy S, Yevzlin AS, Abreo K, Allon M, Asif A, Astor BC, Glickman MH, Graham J, Moist LM, Rajan DK, Roberts C, Vachharajani TJ, Valentini RP. National Kidney Foundation. KDOQI clinical practice guideline for vascular access: 2019 update. Am J Kidney Dis. 2020;75:S1\u2013164.","journal-title":"Am J Kidney Dis"},{"key":"3924_CR4","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1681\/ASN.V74523","volume":"7","author":"HI Feldman","year":"1996","unstructured":"Feldman HI, Kobrin S, Wasserstein A. Hemodialysis vascular access morbidity. J Am Soc Nephrol. 1996;7:523\u201335.","journal-title":"J Am Soc Nephrol"},{"key":"3924_CR5","doi-asserted-by":"publisher","first-page":"5699","DOI":"10.1038\/s41598-021-85267-6","volume":"11","author":"YS Yap","year":"2021","unstructured":"Yap YS, Chi WC, Lin CH, Liu YC, Wu YW. Association of early failure of arteriovenous fistula with mortality in hemodialysis patients. Sci Rep. 2021;11:5699.","journal-title":"Sci Rep"},{"key":"3924_CR6","doi-asserted-by":"publisher","first-page":"e1004651","DOI":"10.1371\/journal.ppat.1004651","volume":"11","author":"P Kruger","year":"2015","unstructured":"Kruger P, Saffarzadeh M, Weber AN, Rieber N, Radsak M, von Bernuth H, Benarafa C, Roos D, Skokowa J, Hartl D. Neutrophils: between host defense, immune modulation, and tissue injury. PLOS Pathog. 2015;11:e1004651.","journal-title":"PLOS Pathog"},{"key":"3924_CR7","doi-asserted-by":"publisher","first-page":"9671604","DOI":"10.1155\/2017\/9671604","volume":"2017","author":"TS Teng","year":"2017","unstructured":"Teng TS, Ji AL, Ji XY, Li YZ. Neutrophils and immunity: from bactericidal action to being conquered. J Immunol Res. 2017;2017:9671604.","journal-title":"J Immunol Res"},{"key":"3924_CR8","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1007\/s11255-019-02166-6","volume":"51","author":"J Diaz-Martinez","year":"2019","unstructured":"Diaz-Martinez J, Campa A, Delgado-Enciso I, Hain D, George F, Huffman F, Baum M. The relationship of blood neutrophil-to-lymphocyte ratio with nutrition markers and health outcomes in hemodialysis patients. Int Urol Nephrol. 2019;51:1239\u201347.","journal-title":"Int Urol Nephrol"},{"key":"3924_CR9","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1586\/14779072.2016.1154788","volume":"14","author":"ME Afari","year":"2016","unstructured":"Afari ME, Bhat T. Neutrophil to lymphocyte ratio (NLR) and cardiovascular diseases: an update. Expert Rev Cardiovasc Ther. 2016;14:573\u20137.","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"3924_CR10","doi-asserted-by":"publisher","first-page":"2530","DOI":"10.1007\/s00268-018-4510-4","volume":"42","author":"JH Choi","year":"2018","unstructured":"Choi JH, Suh YS, Choi Y, Han J, Kim TH, Park SH, Kong SH, Lee HJ, Yang HK. Comprehensive analysis of the neutrophil-to-lymphocyte ratio for preoperative prognostic prediction nomogram in gastric cancer. World J Surg. 2018;42:2530\u201341.","journal-title":"World J Surg"},{"key":"3924_CR11","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1681\/ASN.2016030317","volume":"28","author":"SJ Bernelot Moens","year":"2017","unstructured":"Bernelot Moens SJ, Verweij SL, van der Valk FM, van Capelleveen JC, Kroon J, Versloot M, Verberne HJ, Marquering HA, Duivenvoorden R, Vogt L, Stroes ES. Arterial and cellular inflammation in patients with CKD. J Am Soc Nephrol. 2017;28:1278\u201385.","journal-title":"J Am Soc Nephrol"},{"key":"3924_CR12","doi-asserted-by":"publisher","first-page":"F1501","DOI":"10.1152\/ajprenal.00195.2018","volume":"315","author":"Y Sato","year":"2018","unstructured":"Sato Y, Yanagita M. Immune cells and inflammation in AKI to chronic kidney disease progression. Am J Physiol Ren Physiol. 2018;315:F1501\u201312.","journal-title":"Am J Physiol Ren Physiol"},{"key":"3924_CR13","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.3389\/fphar.2019.01192","volume":"10","author":"V Andrade-Oliveira","year":"2019","unstructured":"Andrade-Oliveira V, Foresto-Neto O, Watanabe IK, Zatz R, C\u00e2mara NO. Inflammation in renal diseases: new and old players. Front Pharmacol. 2019;10:1192.","journal-title":"Front Pharmacol"},{"key":"3924_CR14","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1159\/000448058","volume":"44","author":"HJ Kim","year":"2016","unstructured":"Kim HJ, Lee H, Kim DK, Oh KH, Kim YS, Ahn C, Han JS, Min SK, Min SI, Kim HC, Joo KW. Recurrent vascular access dysfunction as a novel marker of cardiovascular outcome and mortality in hemodialysis patients. Am J Nephrol. 2016;44:71\u201380.","journal-title":"Am J Nephrol"},{"key":"3924_CR15","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.ijcard.2017.02.095","volume":"238","author":"L Ma","year":"2017","unstructured":"Ma L, Zhao S. Risk factors for mortality in patients undergoing hemodialysis: a systematic review and meta-analysis. Int J Cardiol. 2017;238:151\u20138.","journal-title":"Int J Cardiol"}],"container-title":["BMC Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-024-03924-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12882-024-03924-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-024-03924-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T01:05:10Z","timestamp":1735866310000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcnephrol.biomedcentral.com\/articles\/10.1186\/s12882-024-03924-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,2]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3924"],"URL":"https:\/\/doi.org\/10.1186\/s12882-024-03924-0","relation":{},"ISSN":["1471-2369"],"issn-type":[{"value":"1471-2369","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,2]]},"assertion":[{"value":"14 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The three institutions involved in this study received institutional review board approval to conduct the research (Korea University ANAM Hospital 2023AN0159, Korea University GURO Hospital 2023GR0523, and Korea University ANSAN Hospital 2023AS0099). The need for consent to participate was waived by the Institutional Review Board (IRB).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Consent to publish identifying images or details of participants was obtained where applicable. All authors have consented to the publication of this manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}}],"article-number":"2"}}