{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T20:07:40Z","timestamp":1760731660142,"version":"3.38.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:00:00Z","timestamp":1741046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:00:00Z","timestamp":1741046400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"crossref","award":["223499\/Z\/21\/Z"],"award-info":[{"award-number":["223499\/Z\/21\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"crossref"}]},{"name":"UKRI Strength in Places Fund","award":["SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1"],"award-info":[{"award-number":["SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1","SIPF00007\/1"]}]},{"name":"Medical Research Council","award":["MC_UU_00022\/2","MC_UU_00022\/2"],"award-info":[{"award-number":["MC_UU_00022\/2","MC_UU_00022\/2"]}]},{"DOI":"10.13039\/100014589","name":"Chief Scientist Office, Scottish Government Health and Social Care Directorate","doi-asserted-by":"crossref","award":["SPHSU17","SPHSU17"],"award-info":[{"award-number":["SPHSU17","SPHSU17"]}],"id":[{"id":"10.13039\/100014589","id-type":"DOI","asserted-by":"crossref"}]},{"name":"British Heart Foundation Centre for Research Excellence","award":["RE\/18\/6\/34217"],"award-info":[{"award-number":["RE\/18\/6\/34217"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Nephrol"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>NICE guidelines recommend GPs use the kidney failure risk equation (KFRE) to identify people with chronic kidney disease (CKD) at higher risk of kidney failure. Albuminuria results are required to calculate KFRE.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Aim<\/jats:title>\n            <jats:p>Analyse the implementation of KFRE into clinical practice and investigate if albuminuria testing varied amongst patients with CKD, particularly for underserved groups.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Design and setting<\/jats:title>\n            <jats:p>Retrospective cohort study of 23,063 adults in Glasgow from 2013 to 2022.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Method<\/jats:title>\n            <jats:p>We evaluated albuminuria testing rates and the predictive performance of KFRE in estimating 5-year kidney failure risk amongst people with CKD. Logistic regression models quantified associations between demographic\/clinical variables and albuminuria testing. Amongst people who developed kidney failure, we retrospectively assessed the impact of KFRE on the timing of meeting criteria for referral to renal services.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Albuminuria testing was performed in 44.5% of 10,874 adults with CKD. Females (adjusted odds ratio (aOR) 0.86: 95% CI 0.79\u20130.93) and those with hypertension (aOR 0.69: 95% CI 0.63\u20130.77) were less likely to have albuminuria testing. Those aged 40\u201350 years (aOR 1.83: 95% CI 1.15\u20132.91), with diabetes (aOR 2.35: 95% CI 2.14\u20132.58) and living in the least socioeconomically deprived areas (aOR 1.11: 95% CI 1.00-1.23) were more likely to have albuminuria testing. Of 1,352 individuals with incident kidney failure, incorporating KFRE into referral guidelines helped identify high-risk patients early.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>KFRE could be calculated for less than half of people due to lack of albuminuria testing. Focus should be given to improving albuminuria testing and inequities identified to allow wider implementation of KFRE.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s12882-025-04043-0","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T17:03:49Z","timestamp":1741107829000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of the kidney failure risk equation implementation in routine clinical practice and health inequalities in chronic kidney disease care: a retrospective cohort study"],"prefix":"10.1186","volume":"26","author":[{"given":"Heather","family":"Walker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shabana","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandosh","family":"Padmanabhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill P.","family":"Pell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim","family":"Lewsey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Mackay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Dundas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jocelyn M.","family":"Friday","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tran Q. 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The other authors have no potential conflicts of interest to declare.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Delegated research ethics approval was granted for linkage to National Health Service (NHS) patient data by the Local Privacy and Advisory Committee at NHS Greater Glasgow and Clyde. Cohorts and de-identified linked data were prepared by the West of Scotland Safe Haven Research Database at NHS Greater Glasgow and Clyde (IRAS Project ID 321198, REC reference 22\/WS\/1063, West of Scotland REC 4, .).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The other authors have no potential conflicts of interest to declare.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"For the purpose of open access, the author(s) has applied a Creative Commons Attribution (CC BY) licence to any Author Accepted Manuscript version arising from this submission.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Rights retention statement"}}],"article-number":"113"}}