{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T23:17:23Z","timestamp":1784762243305,"version":"3.55.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T00:00:00Z","timestamp":1755907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T00:00:00Z","timestamp":1755907200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Nephrol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Atherosclerotic cardiovascular diseases are the leading causes of morbidity and mortality in patients undergoing peritoneal dialysis and hemodialysis due to end-stage renal disease. Dyslipidemia is a major contributing factor to the development of atherosclerotic cardiovascular diseases, and its prevention is recommended to reduce cardiovascular risk. Several studies have demonstrated the presence of dyslipidemia in patients with chronic kidney disease, and peritoneal dialysis patients have been observed to have a more atherogenic lipid profile compared to those receiving hemodialysis. One of the primary reasons for this is thought to be the absorption of glucose from peritoneal dialysis solutions. In this study, we aimed to assess dyslipidemia in peritoneal dialysis patients and investigate the relationship between glucose absorption from dialysis solutions and lipid profile alterations. A total of 73 patients followed up in the nephrology outpatient clinic were included. Patients\u2019 lipid profiles, the types of dialysis solutions used, and their compositions were statistically analyzed. A statistically significant inverse correlation was found between the amount of glucose absorbed during peritoneal dialysis and HDL cholesterol levels, which was observed both in the overall peritoneal dialysis patient group and in the subgroup undergoing automated peritoneal dialysis (APD). However, no statistically significant relationship was found between glucose absorption and other lipid parameters. Our findings suggest that the glucose content of peritoneal dialysis solutions alone does not play a major role in the development of dyslipidemia when considering all atherogenic lipid parameters. Therefore, dyslipidemia in peritoneal dialysis patients should be evaluated by considering all contributing factors, including treatment-related effects and, in particular, the structural and functional characteristics of the peritoneal membrane.<\/jats:p>","DOI":"10.1186\/s12882-025-04417-4","type":"journal-article","created":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T04:59:11Z","timestamp":1755925151000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effects of different peritoneal dialysis solutions on serum lipid levels and lipid profile in end-stage chronic kidney disease patients undergoing peritoneal dialysis"],"prefix":"10.1186","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2245-5941","authenticated-orcid":false,"given":"Gokhan","family":"Aydin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cevat","family":"Topal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamil","family":"Konur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oguzkan","family":"Ilmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,23]]},"reference":[{"key":"4417_CR1","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1038\/s41572-024-00589-9","volume":"11","author":"P Romagnani","year":"2025","unstructured":"Romagnani P, Agarwal R, Chan JCN, et al. Chronic kidney disease. Nat Rev Dis Primers. 2025;11:8. https:\/\/doi.org\/10.1038\/s41572-024-00589-9.","journal-title":"Nat Rev Dis Primers"},{"issue":"13","key":"4417_CR2","doi-asserted-by":"publisher","first-page":"1294","DOI":"10.1001\/jama.2019.14745","volume":"322","author":"TK Chen","year":"2019","unstructured":"Chen TK, Knicely DH, Grams ME. Chronic kidney disease diagnosis and management. Rev JAMA. 2019;322(13):1294\u2013304. https:\/\/doi.org\/10.1001\/jama.2019.14745.","journal-title":"Rev JAMA"},{"key":"4417_CR3","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2013.11.001","author":"AJ Collins","year":"2014","unstructured":"Collins AJ, Foley RN, Chavers B, Gilbertson D, Herzog C, Ishani A, Johansen K, Kasiske BL, Kutner N, Liu J, Peter S, Guo W, Hu H, Kats Y, Li A, Li S, Maloney S, Roberts J, Skeans T, Snyder M, Agodoa J, L. Am J kidney diseases: official J Natl Kidney Foundation. 2014;63(1 Suppl):A7. https:\/\/doi.org\/10.1053\/j.ajkd.2013.11.001. 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Diabetes. 2016;65(6):1462\u201371. https:\/\/doi.org\/10.2337\/db16-0152.","journal-title":"Diabetes"}],"container-title":["BMC Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-025-04417-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12882-025-04417-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-025-04417-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T11:28:01Z","timestamp":1781609281000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12882-025-04417-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,23]]},"references-count":24,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4417"],"URL":"https:\/\/doi.org\/10.1186\/s12882-025-04417-4","relation":{"references":[{"id-type":"doi","id":"10.1053\/j.ajkd.2013.11.001","asserted-by":"subject"}]},"ISSN":["1471-2369"],"issn-type":[{"value":"1471-2369","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,23]]},"assertion":[{"value":"5 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study permit was granted by the local ethics and thesis committee of our hospital and subsequently approved by the Ministry of Health of the Republic of Turkey. It was also documented by the Thesis Center of the Council of Higher Education of the Republic of Turkey (Reference No: 10578498, Thesis No: 818070; Study Location: Ministry of Health \/ Trabzon Numune Training and Research Hospital \/ Department of Internal Medicine). Official institutional permission was obtained for all data from the center where the study was conducted. All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. Written informed consent was obtained from all subjects prior to participation.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"483"}}