{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T19:04:41Z","timestamp":1793819081365,"version":"4.6.1"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T00:00:00Z","timestamp":1759795200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T00:00:00Z","timestamp":1759795200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Nephrol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Renal involvement in the diffuse large B-cell lymphoma (DLBCL) is rare and usually occurs as part of systemic disease. Muscle infiltration is even less common and can mimic inflammatory or obstructive conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>\n                      We present a 58-year-old male with right flank pain, myalgia, oliguria, and weight loss. Initial evaluation suggested obstructive nephropathy due to ureteral stones, but renal function did not improve after stone removal. Urine cytology revealed atypical lymphoid cells positive for PAX-5.\n                      <jats:sup>18<\/jats:sup>\n                      F-Flourodeoxyglucose Positron Emission Tomography- Magnetic Resonance Imaging (\n                      <jats:sup>18<\/jats:sup>\n                      F-FDG-PET-MRI) showed pathological\n                      <jats:sup>18<\/jats:sup>\n                      F-FDG uptake in the kidneys, multiple muscles, and lymph nodes. Renal biopsy confirmed DLBCL. The patient was treated with daratumumab, rituximab, etoposide, cyclophosphamide, doxorubicin, vincristine, and prednisone, achieving hematologic remission, but remained dialysis-dependent.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case highlights an unusual presentation of secondary renal DLBCL with diffuse muscle involvement, mimicking obstructive acute kidney injury (AKI). The disease should be considered in atypical AKI presentations. Despite systemic treatment response, renal prognosis may be poor in advanced disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12882-025-04503-7","type":"journal-article","created":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T13:22:53Z","timestamp":1759843373000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A case of renal diffuse large B-cell lymphoma concurrent with disseminated muscle involvement"],"prefix":"10.1186","volume":"26","author":[{"given":"Taha Enes","family":"Cetin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Remzi Goktug","family":"Yahyaoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irem","family":"Saribiyik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onur","family":"Ertunc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omer Faruk","family":"Akcay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasemin","family":"Erten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,7]]},"reference":[{"issue":"3","key":"4503_CR1","doi-asserted-by":"publisher","first-page":"548","DOI":"10.3390\/biomedicines13030548","volume":"13","author":"M Witkowska","year":"2025","unstructured":"Witkowska M, et al. Primary renal lymphoma: report of 32 Cases\u2014A retrospective multicenter PLRG analysis. Biomedicines. 2025;13(3):548.","journal-title":"Biomedicines"},{"issue":"4","key":"4503_CR2","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1080\/10428194.2019.1697811","volume":"61","author":"M Kohn","year":"2020","unstructured":"Kohn M, et al. Lymphomas with kidney involvement: the French multicenter retrospective LyKID study. Leuk Lymphoma. 2020;61(4):887\u201395.","journal-title":"Leuk Lymphoma"},{"issue":"1","key":"4503_CR3","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1007\/s00256-024-04680-w","volume":"54","author":"E di Gaeta","year":"2025","unstructured":"di Gaeta E, et al. Extranodal natural killer\/T cell lymphoma of the skeletal muscle. Skeletal Radiol. 2025;54(1):141\u20136.","journal-title":"Skeletal Radiol"},{"issue":"20","key":"4503_CR4","doi-asserted-by":"publisher","first-page":"2655","DOI":"10.2169\/internalmedicine.54.3368","volume":"54","author":"M Hagihara","year":"2015","unstructured":"Hagihara M, et al. Primary renal lymphoma: a case report and literature review. Intern Med. 2015;54(20):2655\u20139.","journal-title":"Intern Med"},{"issue":"5","key":"4503_CR5","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s13244-011-0116-1","volume":"2","author":"L Pallwein-Prettner","year":"2011","unstructured":"Pallwein-Prettner L, et al. Assessment and characterisation of common renal masses with CT and MRI. Insights Imaging. 2011;2(5):543\u201356.","journal-title":"Insights Imaging"},{"issue":"6","key":"4503_CR6","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.2214\/AJR.09.3904","volume":"195","author":"CW Chun","year":"2010","unstructured":"Chun CW, et al. MRI features of skeletal muscle lymphoma. AJR Am J Roentgenol. 2010;195(6):1355\u201360.","journal-title":"AJR Am J Roentgenol"},{"issue":"29","key":"4503_CR7","doi-asserted-by":"publisher","first-page":"7113","DOI":"10.12998\/wjcc.v11.i29.7113","volume":"11","author":"SB Lee","year":"2023","unstructured":"Lee SB, Yoon YM, Hong R. Primary renal lymphoma presenting as renal failure: A case report and review of literature from 1989. World J Clin Cases. 2023;11(29):7113\u201326.","journal-title":"World J Clin Cases"},{"issue":"6","key":"4503_CR8","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1590\/S1677-5538.IBJU.2014.06.08","volume":"40","author":"HS Mirheydar","year":"2014","unstructured":"Mirheydar HS, et al. What is the incidence of kidney stones after chemotherapy in patients with lymphoproliferative or myeloproliferative disorders? Int Braz J Urol. 2014;40(6):772\u201380.","journal-title":"Int Braz J Urol"},{"issue":"8","key":"4503_CR9","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1016\/j.mayocp.2015.04.025","volume":"90","author":"SM Ansell","year":"2015","unstructured":"Ansell SM. Non-Hodgkin lymphoma: diagnosis and treatment. Mayo Clin Proc. 2015;90(8):1152\u201363.","journal-title":"Mayo Clin Proc"},{"issue":"4","key":"4503_CR10","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.3324\/haematol.2018.211904","volume":"105","author":"A Vidal-Crespo","year":"2020","unstructured":"Vidal-Crespo A, et al. Daratumumab displays in vitro and in vivo anti-tumor activity in models of B-cell non-Hodgkin lymphoma and improves responses to standard chemo-immunotherapy regimens. Haematologica. 2020;105(4):1032\u201341.","journal-title":"Haematologica"}],"container-title":["BMC Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-025-04503-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12882-025-04503-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12882-025-04503-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T13:22:53Z","timestamp":1759843373000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcnephrol.biomedcentral.com\/articles\/10.1186\/s12882-025-04503-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,7]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4503"],"URL":"https:\/\/doi.org\/10.1186\/s12882-025-04503-7","relation":{},"ISSN":["1471-2369"],"issn-type":[{"value":"1471-2369","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,7]]},"assertion":[{"value":"28 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 October 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The present work was conducted in accordance with the Declaration of Helsinki and informed consent was obtained from the patient.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Informed consent was obtained from the patient for publication of this case report.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"555"}}