{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T17:54:01Z","timestamp":1781805241928,"version":"3.54.5"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,8,8]],"date-time":"2016-08-08T00:00:00Z","timestamp":1470614400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Neurol"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1186\/s12883-016-0653-9","type":"journal-article","created":{"date-parts":[[2016,8,8]],"date-time":"2016-08-08T12:30:53Z","timestamp":1470659453000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Bi-insular cortical involvement in anti-NMDA-receptor encephalitis \u2013 a case report"],"prefix":"10.1186","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2833-6337","authenticated-orcid":false,"given":"Harald","family":"Hegen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Uprimny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid","family":"Grams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Virgolini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Ramberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronny","family":"Beer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raimund","family":"Helbok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Pfausler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erich","family":"Schmutzhard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,8,8]]},"reference":[{"issue":"1","key":"653_CR1","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1002\/ana.21050","volume":"61","author":"J Dalmau","year":"2007","unstructured":"Dalmau J, Tuzun E, Wu HY, Masjuan J, Rossi JE, Voloschin A, Baehring JM, Shimazaki H, Koide R, King D, et al. Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Ann Neurol. 2007;61(1):25\u201336.","journal-title":"Ann Neurol"},{"issue":"1","key":"653_CR2","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/S1474-4422(10)70253-2","volume":"10","author":"J Dalmau","year":"2011","unstructured":"Dalmau J, Lancaster E, Martinez-Hernandez E, Rosenfeld MR, Balice-Gordon R. Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis. The Lancet Neurology. 2011;10(1):63\u201374.","journal-title":"The Lancet Neurology"},{"issue":"2","key":"653_CR3","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/S1474-4422(12)70310-1","volume":"12","author":"MJ Titulaer","year":"2013","unstructured":"Titulaer MJ, McCracken L, Gabilondo I, Armangue T, Glaser C, Iizuka T, Honig LS, Benseler SM, Kawachi I, Martinez-Hernandez E, et al. Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study. The Lancet Neurology. 2013;12(2):157\u201365.","journal-title":"The Lancet Neurology"},{"issue":"12","key":"653_CR4","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1016\/S1474-4422(08)70224-2","volume":"7","author":"J Dalmau","year":"2008","unstructured":"Dalmau J, Gleichman AJ, Hughes EG, Rossi JE, Peng X, Lai M, Dessain SK, Rosenfeld MR, Balice-Gordon R, Lynch DR. Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. The Lancet Neurology. 2008;7(12):1091\u20138.","journal-title":"The Lancet Neurology"},{"issue":"Pt 6","key":"653_CR5","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1093\/brain\/awq113","volume":"133","author":"SR Irani","year":"2010","unstructured":"Irani SR, Bera K, Waters P, Zuliani L, Maxwell S, Zandi MS, Friese MA, Galea I, Kullmann DM, Beeson D, et al. N-methyl-D-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes. Brain : a journal of neurology. 2010;133(Pt 6):1655\u201367.","journal-title":"Brain : a journal of neurology"},{"key":"653_CR6","doi-asserted-by":"crossref","unstructured":"Heine J, Pruss H, Bartsch T, Ploner CJ, Paul F, Finke C. Imaging of autoimmune encephalitis - relevance for clinical practice and Hippocampal function. Neuroscience. 2015.","DOI":"10.1016\/j.neuroscience.2015.05.037"},{"issue":"Pt 8","key":"653_CR7","doi-asserted-by":"publisher","first-page":"1764","DOI":"10.1093\/brain\/awh526","volume":"128","author":"BM Ances","year":"2005","unstructured":"Ances BM, Vitaliani R, Taylor RA, Liebeskind DS, Voloschin A, Houghton DJ, Galetta SL, Dichter M, Alavi A, Rosenfeld MR, et al. Treatment-responsive limbic encephalitis identified by neuropil antibodies: MRI and PET correlates. Brain : a journal of neurology. 2005;128(Pt 8):1764\u201377.","journal-title":"Brain : a journal of neurology"},{"issue":"11","key":"653_CR8","doi-asserted-by":"publisher","first-page":"2744","DOI":"10.1007\/s00415-013-7048-2","volume":"260","author":"A Baumgartner","year":"2013","unstructured":"Baumgartner A, Rauer S, Mader I, Meyer PT. Cerebral FDG-PET and MRI findings in autoimmune limbic encephalitis: correlation with autoantibody types. J Neurol. 2013;260(11):2744\u201353.","journal-title":"J Neurol"},{"issue":"4","key":"653_CR9","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1002\/ana.20614","volume":"58","author":"R Vitaliani","year":"2005","unstructured":"Vitaliani R, Mason W, Ances B, Zwerdling T, Jiang Z, Dalmau J. Paraneoplastic encephalitis, psychiatric symptoms, and hypoventilation in ovarian teratoma. Ann Neurol. 2005;58(4):594\u2013604.","journal-title":"Ann Neurol"},{"key":"653_CR10","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1186\/1471-2377-14-136","volume":"14","author":"F Wegner","year":"2014","unstructured":"Wegner F, Wilke F, Raab P, Tayeb SB, Boeck AL, Haense C, Trebst C, Voss E, Schrader C, Logemann F, et al. Anti-leucine rich glioma inactivated 1 protein and anti-N-methyl-D-aspartate receptor encephalitis show distinct patterns of brain glucose metabolism in 18\u00a0F-fluoro-2-deoxy-d-glucose positron emission tomography. BMC Neurol. 2014;14:136.","journal-title":"BMC Neurol"},{"issue":"1","key":"653_CR11","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1159\/000323751","volume":"3","author":"K Tojo","year":"2011","unstructured":"Tojo K, Nitta K, Ishii W, Sekijima Y, Morita H, Takahashi Y, Tanaka K, Ikeda S. A young Man with anti-NMDAR encephalitis following Guillain-barre syndrome. Case reports in neurology. 2011;3(1):7\u201313.","journal-title":"Case reports in neurology"},{"issue":"6","key":"653_CR12","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1212\/CPJ.0000000000000074","volume":"4","author":"WO Tobin","year":"2014","unstructured":"Tobin WO, Strand EA, Clark HM, Lowe VJ, Robertson CE, Pittock SJ. NMDA receptor encephalitis causing reversible caudate changes on MRI and PET imaging. Neurology Clinical practice. 2014;4(6):470\u20133.","journal-title":"Neurology Clinical practice"},{"issue":"1","key":"653_CR13","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s11060-006-9200-7","volume":"81","author":"R Koide","year":"2007","unstructured":"Koide R, Shimizu T, Koike K, Dalmau J. EFA6A-like antibodies in paraneoplastic encephalitis associated with immature ovarian teratoma: a case report. J Neuro-Oncol. 2007;81(1):71\u20134.","journal-title":"J Neuro-Oncol"},{"issue":"7","key":"653_CR14","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1136\/jnnp-2011-301969","volume":"83","author":"F Leypoldt","year":"2012","unstructured":"Leypoldt F, Buchert R, Kleiter I, Marienhagen J, Gelderblom M, Magnus T, Dalmau J, Gerloff C, Lewerenz J. Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease. J Neurol Neurosurg Psychiatry. 2012;83(7):681\u20136.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"3","key":"653_CR15","doi-asserted-by":"publisher","first-page":"e0122037","DOI":"10.1371\/journal.pone.0122037","volume":"10","author":"M Ramberger","year":"2015","unstructured":"Ramberger M, Peschl P, Schanda K, Irschick R, Hoftberger R, Deisenhammer F, Rostasy K, Berger T, Dalmau J, Reindl M. Comparison of diagnostic accuracy of microscopy and flow cytometry in evaluating N-methyl-D-aspartate receptor antibodies in serum using a live cell-based assay. PLoS One. 2015;10(3):e0122037.","journal-title":"PLoS One"},{"issue":"10","key":"653_CR16","doi-asserted-by":"publisher","first-page":"1686","DOI":"10.1007\/s00415-010-5604-6","volume":"257","author":"T Iizuka","year":"2010","unstructured":"Iizuka T, Yoshii S, Kan S, Hamada J, Dalmau J, Sakai F, Mochizuki H. Reversible brain atrophy in anti-NMDA receptor encephalitis: a long-term observational study. J Neurol. 2010;257(10):1686\u201391.","journal-title":"J Neurol"},{"issue":"9","key":"653_CR17","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1016\/j.biopsych.2015.02.024","volume":"79","author":"C Finke","year":"2016","unstructured":"Finke C, Kopp UA, Pajkert A, Behrens JR, Leypoldt F, Wuerfel JT, Ploner CJ, Pruss H, Paul F. Structural Hippocampal damage following anti-N-methyl-D-aspartate receptor encephalitis. Biol Psychiatry. 2016;79(9):727\u201334.","journal-title":"Biol Psychiatry"},{"issue":"2","key":"653_CR18","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1002\/ana.23932","volume":"74","author":"C Finke","year":"2013","unstructured":"Finke C, Kopp UA, Scheel M, Pech LM, Soemmer C, Schlichting J, Leypoldt F, Brandt AU, Wuerfel J, Probst C, et al. Functional and structural brain changes in anti-N-methyl-D-aspartate receptor encephalitis. Ann Neurol. 2013;74(2):284\u201396.","journal-title":"Ann Neurol"},{"issue":"5","key":"653_CR19","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1097\/RLU.0000000000001164","volume":"41","author":"J Yuan","year":"2016","unstructured":"Yuan J, Guan H, Zhou X, Niu N, Li F, Cui L, Cui R. Changing brain metabolism patterns in patients with ANMDARE: serial 18\u00a0F-FDG PET\/CT findings. Clin Nucl Med. 2016;41(5):366\u201370.","journal-title":"Clin Nucl Med"}],"container-title":["BMC Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12883-016-0653-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12883-016-0653-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12883-016-0653-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12883-016-0653-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T19:30:50Z","timestamp":1718739050000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcneurol.biomedcentral.com\/articles\/10.1186\/s12883-016-0653-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,8]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["653"],"URL":"https:\/\/doi.org\/10.1186\/s12883-016-0653-9","relation":{},"ISSN":["1471-2377"],"issn-type":[{"value":"1471-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,8]]},"article-number":"130"}}