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Spearman\u2019s correlation analysis between the score on the Modified Barthel Index and the investigated variables evidenced statistical significance for age (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and right- and left-hand grip strength (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.042 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.021, respectively). Statistical significance was not evidenced for the remainder of the variables, including age at onset of symptoms (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.634), age at loss of ambulation (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.664) and age at loss of hand function (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.118).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our analysis allows asserting that the participants exhibited slight dependence until age 35. The greatest losses occurred from ages 35 to 41, and starting at 50, practically all patients become completely dependent. These findings are relevant for determining the prognosis as well as suitable treatment, rehabilitation and assistive technology for these individuals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12883-019-1465-5","type":"journal-article","created":{"date-parts":[[2019,10,27]],"date-time":"2019-10-27T09:02:16Z","timestamp":1572166936000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Motor impairment in a rare form of spastic paraplegia (Spoan syndrome): a 10-year follow-up"],"prefix":"10.1186","volume":"19","author":[{"given":"Cl\u00e1udia R. C.","family":"Galv\u00e3o","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priscilla M. 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