{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:55:59Z","timestamp":1785354959033,"version":"3.55.0"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,11,23]],"date-time":"2019-11-23T00:00:00Z","timestamp":1574467200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,11,23]],"date-time":"2019-11-23T00:00:00Z","timestamp":1574467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Neurol"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n<jats:title>Background<\/jats:title>\n<jats:p>A huge spherical intracranial mass can sometimes be misdiagnosed, due to the lack of typical radiographic features. Thrombosed giant intracranial aneurysms (GIAs) are an uncommon but still a possible differential diagnosis that must be kept in mind to guarantee the best surgical approach and resection of the lesion. We describe an extremely rare case of a huge bifrontal mass mimicking a cystic echinococcosis, in which the surgery unveiled a completely thrombosed GIA of the left anterior cerebral artery (ACA).<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Case presentation<\/jats:title>\n<jats:p>A 61-year-old patient complained about intermittent weakness of the right leg, mild holocephalic headache, beginning cognitive deficits and lethargy. Magnetic resonance imaging (MRI) showed a huge partially calcified and bilobed frontal mass with peripheral edema. Based on a time-resolved angiography with interleaved Stochastic trajectories MRI (TWIST-MRI), a vascular origin of the lesion was considered unlikely. Therefore, the surgery was performed under the suspicion of a cystic echinococcosis but revealed a bilobed GIA of the left ACA with a parent vessel thrombosis. Although only a limited left frontal craniotomy was performed, a proximal control of the parent vessel could be ensured, and the aneurysm was successfully clipped. The patient showed postoperatively no new neurological deficits.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Completely thrombosed GIAs with parent vessel thrombosis are rare lesions that might be misdiagnosed if typical radiographic features are missing. Thus, in case of an intracranial spherical mass with signs of intralesional hemorrhage and mural calcifications, presence of a completely thrombosed GIA should be considered as a possible differential diagnosis.<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s12883-019-1529-6","type":"journal-article","created":{"date-parts":[[2019,11,23]],"date-time":"2019-11-23T18:02:52Z","timestamp":1574532172000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["A rare case of a completely thrombosed bilobed giant intracranial aneurysm of the anterior cerebral artery with spontaneous parent vessel thrombosis: case report"],"prefix":"10.1186","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2376-2211","authenticated-orcid":false,"given":"Mehdi","family":"Chihi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramazan","family":"Jabbarli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Gembruch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Teuber-Hanselmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marvin","family":"Darkwah Oppong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Pierscianek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Radbruch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Glas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Stettner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Sure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,11,23]]},"reference":[{"issue":"1","key":"1529_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00701-013-1933-4","volume":"156","author":"V Nurminen","year":"2014","unstructured":"Nurminen V, Lehecka M, Chakrabarty A, Kivisaari R, Lehto H, Niemel\u00e4 M, et al. Anatomy and morphology of giant aneurysms\u2014angiographic study of 125 consecutive cases. Acta Neurochir. 2014;156(1):1\u201310.","journal-title":"Acta Neurochir"},{"issue":"6","key":"1529_CR2","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/j.neuchi.2015.08.003","volume":"61","author":"M Lonjon","year":"2015","unstructured":"Lonjon M, Pennes F, Sedat J, Bataille B. Epidemiology, genetic, natural history and clinical presentation of giant cerebral aneurysms. Neurochirurgie. 2015;61(6):361\u20135.","journal-title":"Neurochirurgie"},{"issue":"1","key":"1529_CR3","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/s10143-012-0407-0","volume":"36","author":"MLT dos Santos","year":"2013","unstructured":"dos Santos MLT, Spotti AR, dos Santos RMT, Borges MA, Ferrari AF, Colli BO, et al. Giant intracranial aneurysms: morphology and clinical presentation. Neurosurg Rev. 2013;36(1):117\u201322.","journal-title":"Neurosurg Rev"},{"key":"1529_CR4","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.wneu.2018.07.072","volume":"118","author":"KK Das","year":"2018","unstructured":"Das KK, Singh G, Pandey S, Bhaisora KS, Jaiswal A, Behari S. Completely Thrombosed Giant intracranial aneurysm with spontaneous thrombosis of the parent artery: is it Nature's divine intervention and a self-cure? World Neurosurg. 2018;118:132\u20138.","journal-title":"World Neurosurg"},{"key":"1529_CR5","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1093\/neurosurgery\/26.CN_suppl_1.12","volume":"26","author":"CG Drake","year":"1979","unstructured":"Drake CG. Giant intracranial aneurysms: experience with surgical treatment in 174 patients. Clin Neurosurg. 1979;26:12\u201395.","journal-title":"Clin Neurosurg"},{"issue":"9378","key":"1529_CR6","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/S0140-6736(03)13860-3","volume":"362","author":"DO Wiebers","year":"2003","unstructured":"Wiebers DO, Investigators ISoUIA. Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment. Lancet. 2003;362(9378):103\u201310.","journal-title":"Lancet"},{"issue":"3","key":"1529_CR7","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/S0720-048X(03)00090-1","volume":"46","author":"IS Choi","year":"2003","unstructured":"Choi IS, David C. Giant intracranial aneurysms: development, clinical presentation and treatment. Eur J Radiol. 2003;46(3):178\u201394.","journal-title":"Eur J Radiol"},{"issue":"3","key":"1529_CR8","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1007\/BF00451765","volume":"29","author":"O Schubiger","year":"1987","unstructured":"Schubiger O, Valavanis A, Wichmann W. Growth-mechanism of giant intracranial aneurysms; demonstration by CT and MR imaging. Neuroradiology. 1987;29(3):266\u201371.","journal-title":"Neuroradiology"},{"issue":"4","key":"1529_CR9","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1016\/S0967-5868(03)00092-4","volume":"10","author":"MM-H Teng","year":"2003","unstructured":"Teng MM-H, Qadri SN, Luo C-B, Lirng J-F, Chen S-S, Chang C-Y. MR imaging of giant intracranial aneurysm. J Clin Neurosci. 2003;10(4):460\u20134.","journal-title":"J Clin Neurosci"},{"issue":"2","key":"1529_CR10","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/s00701-004-0403-4","volume":"147","author":"P Perrini","year":"2005","unstructured":"Perrini P, Bortolotti C, Wang H, Fraser K, Lanzino G. Thrombosed giant intracavernous aneurysm with subsequent spontaneous ipsilateral carotid artery occlusion. Acta Neurochir. 2005;147(2):215\u20137.","journal-title":"Acta Neurochir"},{"issue":"2","key":"1529_CR11","doi-asserted-by":"publisher","first-page":"287","DOI":"10.3171\/jns.1982.56.2.0287","volume":"56","author":"IR Whittle","year":"1982","unstructured":"Whittle IR, Williams DB, Halmagyi GM, Besser M. Spontaneous thrombosis of a giant intracranial aneurysm and ipsilateral internal carotid artery: case report. J Neurosurg. 1982;56(2):287\u20139.","journal-title":"J Neurosurg"},{"key":"1529_CR12","doi-asserted-by":"publisher","first-page":"955.e1","DOI":"10.1016\/j.wneu.2017.04.172","volume":"103","author":"S Trungu","year":"2017","unstructured":"Trungu S, Bruzzaniti P, Forcato S, Cimatti M, Raco A. Completely thrombosed distal middle cerebral artery aneurysm mimicking a cavernous angioma: case report and review of the literature. World Neurosurg. 2017;103:955.e1\u20134.","journal-title":"World Neurosurg"}],"container-title":["BMC Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12883-019-1529-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12883-019-1529-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12883-019-1529-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,22]],"date-time":"2020-11-22T00:06:51Z","timestamp":1606003611000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcneurol.biomedcentral.com\/articles\/10.1186\/s12883-019-1529-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,23]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["1529"],"URL":"https:\/\/doi.org\/10.1186\/s12883-019-1529-6","relation":{},"ISSN":["1471-2377"],"issn-type":[{"value":"1471-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,23]]},"assertion":[{"value":"8 August 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 November 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The case report has been carried out in accordance with The Code of Ethics of the World Medical Association (Declaration of Helsinki).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"A written informed consent was obtained from the patient.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The work reported in the present manuscript was not supported financially and no conflicts of interest for any of the authors needs to be mentioned.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"297"}}