{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T20:40:03Z","timestamp":1779223203197,"version":"3.51.4"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T00:00:00Z","timestamp":1612483200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T00:00:00Z","timestamp":1612483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Guangxi Appropriate Technology for Medical and Health Research and Development Project","award":["S201415-05"],"award-info":[{"award-number":["S201415-05"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81460203"],"award-info":[{"award-number":["81460203"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Neurol"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although several brain networks play important roles in cervical dystonia (CD) patients, regional homogeneity (ReHo) changes in CD patients have not been clarified. We investigated to explore ReHo in CD patients at rest and analyzed its correlations with symptom severity as measured by Tsui scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 19 CD patients and 21 gender-, age-, and education-matched healthy controls underwent fMRI scans at rest state. Data were analyzed by ReHo method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients showed increased ReHo in the right cerebellum crus I and decreased ReHo in the right superior medial prefrontal cortex (MPFC). Moreover, the right precentral gyrus, right insula, and bilateral middle cingulate gyrus also showed increased ReHo values. A significantly positive correlation was observed between ReHo value in the right cerebellum crus I and symptom severity (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our investigation suggested abnormal ReHo existed in brain regions of the \u201cpain matrix\u201d and salience network (the right insula and bilateral middle cingulate gyrus), the motor network (the right precentral gyrus), the cerebellum and MPFC and further highlighted the significance of these networks in the pathology of CD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12883-021-02079-x","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T02:05:25Z","timestamp":1612490725000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Abnormal regional homogeneity and its relationship with symptom severity in cervical dystonia: a rest state fMRI study"],"prefix":"10.1186","volume":"21","author":[{"given":"Shubao","family":"Wei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunhui","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuqiong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenyan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui Hui","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhong","family":"Qin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiwu","family":"Lei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Qin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caiyou","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4082-6136","authenticated-orcid":false,"given":"Shuguang","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,2,5]]},"reference":[{"issue":"2","key":"2079_CR1","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1002\/mds.870060206","volume":"6","author":"J Chan","year":"1991","unstructured":"Chan J, Brin MF, Fahn S. Idiopathic cervical dystonia: clinical characteristics. Mov Disord. 1991;6(2):119\u201326. https:\/\/doi.org\/10.1002\/mds.870060206.","journal-title":"Mov Disord"},{"key":"2079_CR2","doi-asserted-by":"publisher","first-page":"13","DOI":"10.3389\/fnsys.2010.00013","volume":"4","author":"Y Chao-Gan","year":"2010","unstructured":"Chao-Gan Y, Yu-Feng Z. DPARSF: a MATLAB toolbox for \"pipeline\" data analysis of resting-state fMRI. Front Syst Neurosci. 2010;4:13. https:\/\/doi.org\/10.3389\/fnsys.2010.00013.","journal-title":"Front Syst Neurosci"},{"key":"2079_CR3","doi-asserted-by":"publisher","unstructured":"Charles PD, Manack Adams A, Davis T, Bradley K, Schwartz M, Brin MF, Patel AT. Neck pain and cervical dystonia: treatment outcomes from CD PROBE (cervical dystonia patient registry for observation of OnabotulinumtoxinA efficacy). Pain Pract. 2016. https:\/\/doi.org\/10.1111\/papr.12408.","DOI":"10.1111\/papr.12408"},{"issue":"2","key":"2079_CR4","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.clineuro.2007.09.020","volume":"110","author":"PM de Vries","year":"2008","unstructured":"de Vries PM, Johnson KA, de Jong BM, Gieteling EW, Bohning DE, George MS, Leenders KL. Changed patterns of cerebral activation related to clinically normal hand movement in cervical dystonia. Clin Neurol Neurosurg. 2008;110(2):120\u20138. https:\/\/doi.org\/10.1016\/j.clineuro.2007.09.020.","journal-title":"Clin Neurol Neurosurg"},{"issue":"5","key":"2079_CR5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062877","volume":"8","author":"CC Delnooz","year":"2013","unstructured":"Delnooz CC, Pasman JW, Beckmann CF, van de Warrenburg BP. Task-free functional MRI in cervical dystonia reveals multi-network changes that partially normalize with botulinum toxin. PLoS One. 2013;8(5):e62877. https:\/\/doi.org\/10.1371\/journal.pone.0062877.","journal-title":"PLoS One"},{"issue":"1","key":"2079_CR6","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1007\/s00429-013-0671-y","volume":"220","author":"CC Delnooz","year":"2015","unstructured":"Delnooz CC, Pasman JW, Beckmann CF, van de Warrenburg BP. Altered striatal and pallidal connectivity in cervical dystonia. Brain Struct Funct. 2015;220(1):513\u201323. https:\/\/doi.org\/10.1007\/s00429-013-0671-y.","journal-title":"Brain Struct Funct"},{"issue":"8","key":"2079_CR7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0162191","volume":"11","author":"C Delorme","year":"2016","unstructured":"Delorme C, Roze E, Grabli D, Mayer JM, Degos B, Vidailhet M, Worbe Y. Explicit Agency in Patients with cervical dystonia: altered recognition of temporal discrepancies between motor actions and their feedback. PLoS One. 2016;11(8):e0162191. https:\/\/doi.org\/10.1371\/journal.pone.0162191.","journal-title":"PLoS One"},{"issue":"4","key":"2079_CR8","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1016\/j.neuroimage.2009.03.057","volume":"47","author":"B Draganski","year":"2009","unstructured":"Draganski B, Schneider SA, Fiorio M, Kloppel S, Gambarin M, Tinazzi M, et al. Genotype-phenotype interactions in primary dystonias revealed by differential changes in brain structure. Neuroimage. 2009;47(4):1141\u20137. https:\/\/doi.org\/10.1016\/j.neuroimage.2009.03.057.","journal-title":"Neuroimage"},{"issue":"9","key":"2079_CR9","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.1212\/01.WNL.0000094240.93745.83","volume":"61","author":"B Draganski","year":"2003","unstructured":"Draganski B, Thun-Hohenstein C, Bogdahn U, Winkler J, May A. \"motor circuit\" gray matter changes in idiopathic cervical dystonia. Neurology. 2003;61(9):1228\u201331.","journal-title":"Neurology"},{"issue":"11","key":"2079_CR10","doi-asserted-by":"publisher","first-page":"1538","DOI":"10.1002\/mds.21619","volume":"22","author":"K Egger","year":"2007","unstructured":"Egger K, Mueller J, Schocke M, Brenneis C, Rinnerthaler M, Seppi K, et al. Voxel based morphometry reveals specific gray matter changes in primary dystonia. Mov Disord. 2007;22(11):1538\u201342. https:\/\/doi.org\/10.1002\/mds.21619.","journal-title":"Mov Disord"},{"issue":"3","key":"2079_CR11","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1007\/s00702-015-1488-z","volume":"123","author":"P Filip","year":"2016","unstructured":"Filip P, Sumec R, Balaz M, Bares M. The clinical phenomenology and associations of trick maneuvers in cervical dystonia. J Neural Transm (Vienna). 2016;123(3):269\u201375. https:\/\/doi.org\/10.1007\/s00702-015-1488-z.","journal-title":"J Neural Transm (Vienna)"},{"issue":"1\u20133","key":"2079_CR12","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.jad.2011.06.048","volume":"135","author":"WB Guo","year":"2011","unstructured":"Guo WB, Liu F, Xue ZM, Yu Y, Ma CQ, Tan CL, et al. Abnormal neural activities in first-episode, treatment-naive, short-illness-duration, and treatment-response patients with major depressive disorder: a resting-state fMRI study. J Affect Disord. 2011a;135(1\u20133):326\u201331. https:\/\/doi.org\/10.1016\/j.jad.2011.06.048.","journal-title":"J Affect Disord"},{"issue":"5","key":"2079_CR13","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.1016\/j.pnpbp.2011.02.006","volume":"35","author":"WB Guo","year":"2011","unstructured":"Guo WB, Sun XL, Liu L, Xu Q, Wu RR, Liu ZN, et al. Disrupted regional homogeneity in treatment-resistant depression: a resting-state fMRI study. Prog Neuro-Psychopharmacol Biol Psychiatry. 2011b;35(5):1297\u2013302. https:\/\/doi.org\/10.1016\/j.pnpbp.2011.02.006.","journal-title":"Prog Neuro-Psychopharmacol Biol Psychiatry"},{"issue":"Pt 5","key":"2079_CR14","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1093\/brain\/awh133","volume":"127","author":"KY Haaland","year":"2004","unstructured":"Haaland KY, Prestopnik JL, Knight RT, Lee RR. Hemispheric asymmetries for kinematic and positional aspects of reaching. Brain. 2004;127(Pt 5):1145\u201358. https:\/\/doi.org\/10.1093\/brain\/awh133.","journal-title":"Brain"},{"issue":"1","key":"2079_CR15","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.nec.2013.08.006","volume":"25","author":"AO Hebb","year":"2014","unstructured":"Hebb AO, Zhang JJ, Mahoor MH, Tsiokos C, Matlack C, Chizeck HJ, Pouratian N. Creating the feedback loop: closed-loop neurostimulation. Neurosurg Clin N Am. 2014;25(1):187\u2013204. https:\/\/doi.org\/10.1016\/j.nec.2013.08.006.","journal-title":"Neurosurg Clin N Am"},{"issue":"2","key":"2079_CR16","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1007\/s00429-007-0150-4","volume":"212","author":"WB Hoover","year":"2007","unstructured":"Hoover WB, Vertes RP. Anatomical analysis of afferent projections to the medial prefrontal cortex in the rat. Brain Struct Funct. 2007;212(2):149\u201379. https:\/\/doi.org\/10.1007\/s00429-007-0150-4.","journal-title":"Brain Struct Funct"},{"issue":"7","key":"2079_CR17","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1212\/WNL.41.7.1088","volume":"41","author":"J Jankovic","year":"1991","unstructured":"Jankovic J, Leder S, Warner D, Schwartz K. Cervical dystonia: clinical findings and associated movement disorders. Neurology. 1991;41(7):1088\u201391.","journal-title":"Neurology"},{"key":"2079_CR18","doi-asserted-by":"publisher","first-page":"7349894","DOI":"10.1155\/2019\/7349894","volume":"2019","author":"W Jiang","year":"2019","unstructured":"Jiang W, Lei Y, Wei J, Yang L, Wei S, Yin Q, et al. Alterations of Interhemispheric functional connectivity and degree centrality in cervical dystonia: a resting-state fMRI study. Neural Plast. 2019;2019:7349894. https:\/\/doi.org\/10.1155\/2019\/7349894.","journal-title":"Neural Plast"},{"issue":"7","key":"2079_CR19","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1002\/mds.25567","volume":"28","author":"HA Jinnah","year":"2013","unstructured":"Jinnah HA, Berardelli A, Comella C, Defazio G, Delong MR, Factor S, et al. The focal dystonias: current views and challenges for future research. Mov Disord. 2013;28(7):926\u201343. https:\/\/doi.org\/10.1002\/mds.25567.","journal-title":"Mov Disord"},{"issue":"10","key":"2079_CR20","doi-asserted-by":"publisher","first-page":"1740","DOI":"10.1212\/01.wnl.0000246112.19504.61","volume":"67","author":"HA Jinnah","year":"2006","unstructured":"Jinnah HA, Hess EJ. A new twist on the anatomy of dystonia: the basal ganglia and the cerebellum? Neurology. 2006;67(10):1740\u20131. https:\/\/doi.org\/10.1212\/01.wnl.0000246112.19504.61.","journal-title":"Neurology"},{"issue":"10","key":"2079_CR21","doi-asserted-by":"publisher","first-page":"2485","DOI":"10.1093\/cercor\/bhp135","volume":"19","author":"FM Krienen","year":"2009","unstructured":"Krienen FM, Buckner RL. Segregated fronto-cerebellar circuits revealed by intrinsic functional connectivity. Cereb Cortex. 2009;19(10):2485\u201397. https:\/\/doi.org\/10.1093\/cercor\/bhp135.","journal-title":"Cereb Cortex"},{"issue":"1","key":"2079_CR22","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.pneurobio.2010.10.005","volume":"93","author":"V Legrain","year":"2011","unstructured":"Legrain V, Iannetti GD, Plaghki L, Mouraux A. The pain matrix reloaded: a salience detection system for the body. Prog Neurobiol. 2011;93(1):111\u201324. https:\/\/doi.org\/10.1016\/j.pneurobio.2010.10.005.","journal-title":"Prog Neurobiol"},{"issue":"3","key":"2079_CR23","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1002\/ana.23951","volume":"74","author":"S Little","year":"2013","unstructured":"Little S, Pogosyan A, Neal S, Zavala B, Zrinzo L, Hariz M, et al. Adaptive deep brain stimulation in advanced Parkinson disease. Ann Neurol. 2013;74(3):449\u201357. https:\/\/doi.org\/10.1002\/ana.23951.","journal-title":"Ann Neurol"},{"issue":"1","key":"2079_CR24","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1097\/01.wnr.0000195666.22714.35","volume":"17","author":"H Liu","year":"2006","unstructured":"Liu H, Liu Z, Liang M, Hao Y, Tan L, Kuang F, et al. Decreased regional homogeneity in schizophrenia: a resting state functional magnetic resonance imaging study. Neuroreport. 2006;17(1):19\u201322.","journal-title":"Neuroreport"},{"key":"2079_CR25","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.neuroscience.2016.09.045","volume":"339","author":"J Martin-Cortecero","year":"2016","unstructured":"Martin-Cortecero J, Nunez A. Sensory responses in the medial prefrontal cortex of anesthetized rats. Implications for sensory processing. Neuroscience. 2016;339:109\u201323. https:\/\/doi.org\/10.1016\/j.neuroscience.2016.09.045.","journal-title":"Neuroscience"},{"key":"2079_CR26","unstructured":"MATLAB. 2012b.\u00a0https:\/\/www.mathworks.com."},{"issue":"2","key":"2079_CR27","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1002\/mdc3.12238","volume":"3","author":"ES Molho","year":"2016","unstructured":"Molho ES, Stacy M, Gillard P, Charles D, Adler CH, Jankovic J, et al. Impact of cervical dystonia on work productivity: an analysis from a patient registry. Mov Disord Clin Pract. 2016;3(2):130\u20138. https:\/\/doi.org\/10.1002\/mdc3.12238.","journal-title":"Mov Disord Clin Pract"},{"key":"2079_CR28","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/s0079-6123(04)48013-3","volume":"148","author":"MF Nitschke","year":"2005","unstructured":"Nitschke MF, Arp T, Stavrou G, Erdmann C, Heide W. The cerebellum in the cerebro-cerebellar network for the control of eye and hand movements--an fMRI study. Prog Brain Res. 2005;148:151\u201364. https:\/\/doi.org\/10.1016\/s0079-6123(04)48013-3.","journal-title":"Prog Brain Res"},{"issue":"8","key":"2079_CR29","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1002\/mds.21495","volume":"22","author":"M Obermann","year":"2007","unstructured":"Obermann M, Yaldizli O, De Greiff A, Lachenmayer ML, Buhl AR, Tumczak F, et al. Morphometric changes of sensorimotor structures in focal dystonia. Mov Disord. 2007;22(8):1117\u201323. https:\/\/doi.org\/10.1002\/mds.21495.","journal-title":"Mov Disord"},{"key":"2079_CR30","doi-asserted-by":"publisher","unstructured":"Pan P, Wei S, Ou Y, Jiang W, Li W, Lei Y, et al. Reduced Global-Brain Functional Connectivity and Its Relationship With Symptomatic Severity in Cervical Dystonia. Front Neurol. 2020;10. https:\/\/doi.org\/10.3389\/fneur.2019.01358.","DOI":"10.3389\/fneur.2019.01358"},{"issue":"5","key":"2079_CR31","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/S0987-7053(00)00227-6","volume":"30","author":"R Peyron","year":"2000","unstructured":"Peyron R, Laurent B, Garcia-Larrea L. Functional imaging of brain responses to pain. A review and meta-analysis (2000). Neurophysiol Clin. 2000;30(5):263\u201388.","journal-title":"Neurophysiol Clin"},{"issue":"17","key":"2079_CR32","doi-asserted-by":"publisher","first-page":"7825","DOI":"10.1523\/JNEUROSCI.22-17-07825.2002","volume":"22","author":"CE Pizoli","year":"2002","unstructured":"Pizoli CE, Jinnah HA, Billingsley ML, Hess EJ. Abnormal cerebellar signaling induces dystonia in mice. J Neurosci. 2002;22(17):7825\u201333.","journal-title":"J Neurosci"},{"issue":"2","key":"2079_CR33","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.brainresrev.2007.11.006","volume":"58","author":"M Pong","year":"2008","unstructured":"Pong M, Horn KM, Gibson AR. Pathways for control of face and neck musculature by the basal ganglia and cerebellum. Brain Res Rev. 2008;58(2):249\u201364. https:\/\/doi.org\/10.1016\/j.brainresrev.2007.11.006.","journal-title":"Brain Res Rev"},{"key":"2079_CR34","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1186\/1471-2202-14-123","volume":"14","author":"T Prell","year":"2013","unstructured":"Prell T, Peschel T, Kohler B, Bokemeyer MH, Dengler R, Gunther A, Grosskreutz J. Structural brain abnormalities in cervical dystonia. BMC Neurosci. 2013;14:123. https:\/\/doi.org\/10.1186\/1471-2202-14-123.","journal-title":"BMC Neurosci"},{"key":"2079_CR35","doi-asserted-by":"publisher","unstructured":"Ramdhani RA, Simonyan K. Primary dystonia: conceptualizing the disorder through a structural brain imaging lens. Tremor Other Hyperkinet Mov (N Y). 2013;3. https:\/\/doi.org\/10.7916\/d8h70dj7.","DOI":"10.7916\/d8h70dj7"},{"issue":"9","key":"2079_CR36","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1136\/jnnp-2013-306971","volume":"85","author":"VF Ramos","year":"2014","unstructured":"Ramos VF, Karp BI, Hallett M. Tricks in dystonia: ordering the complexity. J Neurol Neurosurg Psychiatry. 2014;85(9):987\u201393. https:\/\/doi.org\/10.1136\/jnnp-2013-306971.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"2","key":"2079_CR37","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.ijpsycho.2015.05.012","volume":"97","author":"Y Song","year":"2015","unstructured":"Song Y, Su Q, Jiang M, Liu F, Yao D, Dai Y, et al. Abnormal regional homogeneity and its correlations with personality in first-episode, treatment-naive somatization disorder. Int J Psychophysiol. 2015;97(2):108\u201312. https:\/\/doi.org\/10.1016\/j.ijpsycho.2015.05.012.","journal-title":"Int J Psychophysiol"},{"issue":"5","key":"2079_CR38","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1016\/j.neubiorev.2008.08.013","volume":"33","author":"CM Stinear","year":"2009","unstructured":"Stinear CM, Coxon JP, Byblow WD. Primary motor cortex and movement prevention: where stop meets go. Neurosci Biobehav Rev. 2009;33(5):662\u201373. https:\/\/doi.org\/10.1016\/j.neubiorev.2008.08.013.","journal-title":"Neurosci Biobehav Rev"},{"issue":"7","key":"2079_CR39","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0099273","volume":"9","author":"Q Su","year":"2014","unstructured":"Su Q, Yao D, Jiang M, Liu F, Jiang J, Xu C, et al. Dissociation of regional activity in default mode network in medication-naive, first-episode somatization disorder. PLoS One. 2014;9(7):e99273. https:\/\/doi.org\/10.1371\/journal.pone.0099273.","journal-title":"PLoS One"},{"issue":"9","key":"2079_CR40","doi-asserted-by":"publisher","first-page":"2731","DOI":"10.1002\/hbm.20705","volume":"30","author":"KS Taylor","year":"2009","unstructured":"Taylor KS, Seminowicz DA, Davis KD. Two systems of resting state connectivity between the insula and cingulate cortex. Hum Brain Mapp. 2009;30(9):2731\u201345. https:\/\/doi.org\/10.1002\/hbm.20705.","journal-title":"Hum Brain Mapp"},{"key":"2079_CR41","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.parkreldis.2019.06.009","volume":"65","author":"M Tinazzi","year":"2019","unstructured":"Tinazzi M, Squintani GM, Bhatia KP, Segatti A, Donato F, Valeriani M, Erro R. Pain in cervical dystonia: evidence of abnormal inhibitory control. Parkinsonism Relat Disord. 2019;65:252\u20135. https:\/\/doi.org\/10.1016\/j.parkreldis.2019.06.009.","journal-title":"Parkinsonism Relat Disord"},{"issue":"10","key":"2079_CR42","doi-asserted-by":"publisher","first-page":"2060","DOI":"10.1007\/s00415-012-6454-1","volume":"259","author":"M Tinazzi","year":"2012","unstructured":"Tinazzi M, Valeriani M, Squintani G, Corra F, Recchia S, Defazio G, Berardelli A. Nociceptive pathway function is normal in cervical dystonia: a study using laser-evoked potentials. J Neurol. 2012;259(10):2060\u20136. https:\/\/doi.org\/10.1007\/s00415-012-6454-1.","journal-title":"J Neurol"},{"issue":"8501","key":"2079_CR43","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/S0140-6736(86)92070-2","volume":"2","author":"JK Tsui","year":"1986","unstructured":"Tsui JK, Eisen A, Stoessl AJ, Calne S, Calne DB. Double-blind study of botulinum toxin in spasmodic torticollis. Lancet. 1986;2(8501):245\u20137.","journal-title":"Lancet"},{"key":"2079_CR44","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.jad.2015.12.052","volume":"193","author":"S Wei","year":"2016","unstructured":"Wei S, Su Q, Jiang M, Liu F, Yao D, Dai Y, et al. Abnormal default-mode network homogeneity and its correlations with personality in drug-naive somatization disorder at rest. J Affect Disord. 2016;193:81\u20138. https:\/\/doi.org\/10.1016\/j.jad.2015.12.052.","journal-title":"J Affect Disord"},{"key":"2079_CR45","doi-asserted-by":"publisher","unstructured":"Wolpert DM, Goodbody SJ, Husain M. Maintaining internal representations: the role of the human superior parietal lobe. Nat Neurosci. 1998;1(6):529\u201333. https:\/\/doi.org\/10.1038\/2245.","DOI":"10.1038\/2245"},{"issue":"1","key":"2079_CR46","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/j.neuroimage.2003.12.030","volume":"22","author":"Y Zang","year":"2004","unstructured":"Zang Y, Jiang T, Lu Y, He Y, Tian L. Regional homogeneity approach to fMRI data analysis. Neuroimage. 2004;22(1):394\u2013400. https:\/\/doi.org\/10.1016\/j.neuroimage.2003.12.030.","journal-title":"Neuroimage"},{"issue":"3","key":"2079_CR47","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1016\/j.neuroimage.2011.02.045","volume":"56","author":"E Zoons","year":"2011","unstructured":"Zoons E, Booij J, Nederveen AJ, Dijk JM, Tijssen MA. Structural, functional and molecular imaging of the brain in primary focal dystonia--a review. Neuroimage. 2011;56(3):1011\u201320. https:\/\/doi.org\/10.1016\/j.neuroimage.2011.02.045.","journal-title":"Neuroimage"}],"container-title":["BMC Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12883-021-02079-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12883-021-02079-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12883-021-02079-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T02:06:23Z","timestamp":1612490783000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcneurol.biomedcentral.com\/articles\/10.1186\/s12883-021-02079-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,5]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["2079"],"URL":"https:\/\/doi.org\/10.1186\/s12883-021-02079-x","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-40820\/v1","asserted-by":"object"},{"id-type":"doi","id":"10.21203\/rs.3.rs-40820\/v3","asserted-by":"object"},{"id-type":"doi","id":"10.21203\/rs.3.rs-40820\/v2","asserted-by":"object"}]},"ISSN":["1471-2377"],"issn-type":[{"value":"1471-2377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,5]]},"assertion":[{"value":"2 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 February 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The ethics committee of the First Affiliated Hospital, Guangxi Medical University approved our study. All participants were given information regarding study procedures and subsequently provided written informed consent.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"None.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"55"}}